Methadone

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9
Abdominal cramps def x x x x x x x x
Abdominal pain def x x x x x x x
Amenorrhoea def x x x x x x x
Anorexia def x x x x x x x x x
Anxiety def x x x x x x x x
Arrhythmia def x x x x x x x x
Asthenia def x x x x x x x
Confusional state def x x x x x x x x x
Constipation def x x x x x x x x x
Libido decreased def x x x x x x x
Diarrhoea def x x x x x x x x
Dizziness def x x x x x x x x x
Drug abuse def x
Dyspnoea def x
Oedema def x x x x x x x
Rash def x x x x x x x x x
Body temperature increased def x x x x x x x x
Flushing def x x x x x x x x x
Glossitis def x x x x x x x
Hallucination def x x x x x
Headache def x x x x x x x
Cardiac arrest def x x x x x x x x x
Cardiac failure def x x x x x x x x x
Hepatitis def x x x x x x x x x
Chronic hepatitis def x x x x x x x x x
Hypokalaemia def x x x x x x x x x
Hypotension def x x x x x x x x x
Irritability def x x x x x x x x
Cramp muscle def x x x x x x x x
Mydriasis def x x x x x x x x
Nausea def x x x x x x x x x
Palpitations def x x x x x x x x x
Phlebitis def x x x x x x x x x
Pruritus def x x x x x x x x x
Pulmonary oedema def x x x x x x x
Seizures def x x x x x x x x x
Shock def x x x x x x x x x
Sneezing def x x x x x x x x
Muscle spasms def x x x x x x x x x
Sweating def x x x x x x x x x
Swelling def x
Syncope def x x x x x x x x x
Tachycardia def x x x x x x x x x
Thrombocytopenia def x x x x x x x x x
Torsade de pointes def x x x x x x x x x
Tremor def x x x x x x x x
Erythema def x
Urticaria def x x x x x x x x x
Ventricular fibrillation def x x x x x x x x x
Ventricular tachycardia def x x x x x x x x x
Vomiting def x x x x x x x x x
Weight increased def x x x x x x x x x
Weight decreased def x x x x x x x x
Dry mouth def x x x x x x x
Yawning def x x x x x x x x
Urinary retention def x x x x x x x
Agitation def x x x x x x x x x
Hypomagnesaemia def x x x x x x x x x
Electrocardiogram QT prolonged def x x x x
Urinary hesitation x x x x x x x
Respiratory arrest x x x x x x x x x
Lightheadedness x x x x x x x x x
Muscle twitching def x x x x x x x x
Cardiac fibrillation x x x x x x x x x
Disorientation x x x x x x x x x
Dysphoria x x x x x x x x x
Ache def x x x x x x x x
Respiratory depression x x x x x x x x x
Euphoric mood def x x x x x x x x x
Dependence physiological def x
Extrasystoles def x x x x x x x x
Analgesia x
Lacrimation def x x x x x x x x
Withdrawn x x x x x x x x
Bowel spasm x x x x x x x x
Bradycardia def x x x x x x x x
Visual disturbance x x x x x x x x
Sedation x x x x x x x x x
Anguish def x x x x x x x x x
Sweating increased x x x x x x x x
Coldness x x x x x x x x
Cardiomyopathy def x x x x x x x x x
Insomnia def x x x x x x x x x
Rhinorrhoea def x x x x x x x x
Death x x x x x x x x x
Drug dependence def x
Weakness def x x x x x x x x x
Indication Labels
Addiction def x x x x x x x x x
Dependence def x
Dependence on opiates x
Pain def x x x x
Substance abuse def x x x x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: N07BC02

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. click product name to read prescribing information / Methadone Hydrochloride Injection : 62 side effects (FDA MedWatch)
  2. METHADONE HYDROCHLORIDE / METHADOSE : 65 side effects (Drugs@FDA)
  3. METHADONE HYDROCHLORIDE / METHADONE HYDROCHLORIDE : 68 side effects (Drugs@FDA)
  4. METHADONE : 79 side effects (FDA XML label)
  5. methadone : 79 side effects (FDA XML label)
  6. METHADONE : 78 side effects (FDA XML label)
  7. Methadone : 79 side effects (FDA XML label)
  8. METHADONE HYDROCHLORIDE / DOLOPHINE HYDROCHLORIDE : 79 side effects (Drugs@FDA)
  9. METHADONE : 84 side effects (FDA XML label)