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Side effects

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MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Haemorrhage Haemorrhage common, 1.13% - 1.37% x x
Haemoglobin Haemorrhage common, 1.13% - 1.37% x x
Anaemia Anaemia common, 2.58% - 3.01% x x
Epistaxis Epistaxis uncommon — 1.55% - 3.58% 1.09% x x
Haemorrhagic anaemia Haemorrhagic anaemia 2.58% - 3.01% x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage uncommon, common x x
Haematemesis Haematemesis uncommon, common x x
Melaena Melaena uncommon, common x x
Nausea Nausea common, 2.58% - 2.69% x x
Conjunctival haemorrhage Conjunctival haemorrhage rare, common x x
Eye haemorrhage Eye haemorrhage rare, common x x
Contusion Contusion common, 1.4% - 2.22% 2.18% x x
Haematuria Haematuria uncommon — 1.43% - 2.1% 1.09% x x
Blood urine x
Haematoma Haematoma common, 1.13% - 1.97% 1.21% x x
Menorrhagia Menorrhagia 1.42% x
Urethral haemorrhage Urethral haemorrhage common, 1.13% - 1.37% x x
Gingival bleeding Gingival bleeding rare — 0.972% - 1.43% 0.363% x x
Rectal haemorrhage Rectal haemorrhage rare — 0.972% x x
Wound haemorrhage Wound haemorrhage uncommon, 0.912% - 1.02% x x
Catheter site haemorrhage Catheter site haemorrhage uncommon, 0.912% - 1.02% x x
Post procedural haematoma Post procedural haematoma uncommon, 0.912% - 1.02% x x
Vessel puncture site haematoma Vessel puncture site haematoma uncommon, 0.912% - 1.02% x x
Alanine aminotransferase increased Alanine aminotransferase increased uncommon, 0.844% - 1.2% x x
Transaminases increased Transaminases increased uncommon, 0.844% - 1.2% x x
Alanine aminotransferase abnormal Alanine aminotransferase abnormal uncommon, 0.844% - 1.2% x x
Aspartate aminotransferase increased Aspartate aminotransferase increased uncommon, 0.793% - 1.17% x x
Post procedural haemorrhage Post procedural haemorrhage uncommon, 0.912% - 1.02% x x
Gamma-glutamyltransferase increased Gamma-glutamyltransferase increased uncommon, 0.641% - 1.1% x x
Haemoptysis Haemoptysis rare, 1.2% x x
Anaphylactic shock Anaphylactic shock uncommon x x
Dermatitis Rash uncommon x x
Rash Rash uncommon x x
Haematochezia Haematochezia uncommon x x
Subdural haematoma Subdural haematoma uncommon x
Hypotension Hypotension uncommon x x
Mouth haemorrhage Mouth haemorrhage uncommon x
Subarachnoid haemorrhage Subarachnoid haemorrhage uncommon x
Thrombocytopenia Thrombocytopenia uncommon x x
Traumatic haemorrhage Traumatic haemorrhage uncommon x
Procedural haemorrhage Intraoperative hemorrhage uncommon x x
Liver function test abnormal Liver function test abnormal uncommon x x
Intra-abdominal haemorrhage Intra-abdominal haemorrhage uncommon x
Haemorrhoidal haemorrhage Haemorrhoidal haemorrhage uncommon x x
Blood bilirubin increased Blood bilirubin increased uncommon x x
Wound secretion Wound secretion uncommon x x
Allergic oedema Allergic oedema uncommon x x
Blood alkaline phosphatase increased Blood alkaline phosphatase increased uncommon x x
Spinal haematoma Spinal haematoma uncommon x
Occult blood positive Occult blood positive uncommon x x
Application site haemorrhage Application site haemorrhage uncommon x
Urogenital haemorrhage Urogenital haemorrhage uncommon x
Incision site haemorrhage Incision site haemorrhage uncommon x x
Incision site haematoma Incision site haematoma uncommon x x
Procedural hypotension Procedural hypotension uncommon x x
Cerebral haemorrhage Cerebral haemorrhage uncommon x
Haemorrhagic stroke x
Vaginal haemorrhage Vaginal haemorrhage uncommon x x
Spinal cord haemorrhage Intraspinal bleeding uncommon x
Hypersensitivity Hypersensitivity rare, uncommon x x
Muscle haemorrhage Muscle haemorrhage rare x x
Retroperitoneal haemorrhage Retroperitoneal haemorrhage rare x
Respiratory tract haemorrhage Respiratory tract haemorrhage rare x
Pharyngeal haemorrhage Pharyngeal haemorrhage rare x
Pulmonary alveolar haemorrhage Pulmonary alveolar haemorrhage rare x
Laryngeal haemorrhage Laryngeal haemorrhage rare x
Breast disorder Breast disorder x x
Compartment syndrome Compartment syndrome x
Connective tissue disorder Connective tissue disorder x x
Diabetes mellitus Diabetes mellitus x
Drug hypersensitivity Drug hypersensitivity x
Ecchymosis Ecchymosis x
Eye disorder Eye disorder x x
Gastrointestinal disorder Gastrointestinal disorder x x
Immune system disorder Immune system disorder x
Mediastinal disorder Mediastinal disorder x x
Metrorrhagia Metrorrhagia x
Nervous system disorder Nervous system disorder x
Petechiae Petechiae x
Retinal haemorrhage Retinal haemorrhage x
Dizziness Syncope x
Shock Syncope x
Syncope Syncope x
Loss of consciousness Syncope x
Urethral disorder Urinary tract disorder x x
Urinary tract disorder Urinary tract disorder x x
Angiopathy Angiopathy x x
Haemorrhage intracranial Haemorrhage intracranial x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x
Blood urine Blood urine x
Blood urine present Blood urine x
Blood urine present x
Menometrorrhagia Menometrorrhagia x
Hepatobiliary disease Hepatobiliary disease x x
Anal haemorrhage Anal haemorrhage x
Periorbital haematoma Periorbital haematoma x
Injection site haematoma Injection site haematoma x
Traumatic haematoma Traumatic haematoma x
Haemorrhagic stroke Haemorrhagic stroke x
Skin haemorrhage Skin haemorrhage x
Genital haemorrhage Genital haemorrhage x


Information about indications was extracted from the indications and usage sections of the labels.

apixaban / apixaban

Side effects:71


Side effects:76
Source:FDA Structured Product Label

Color scheme:


    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    no frequency information
    not found on label