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Crizotinib

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Codes: None found

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3
Diarrhoea 0% - 60% x x x
Constipation 0% - 42% x x x
Lymphopenia 9% - 60% x
Eye disorder 0% - 59.9% x x x
Nausea 1% - 55% x x x
Disorder sight 0% - 60% x x x
Fatigue 26% - 27% x x x
Decreased appetite 2.33% - 27.3% x x x
Vomiting 0% - 47% x x x
Oedema 0% - 39% x x x
Malnutrition 2.33% - 27.3% x x
Dysgeusia 0% - 26% x x x
Neutropenia 2% - 49% x x
Leukopenia 9% x x
Rash 0% - 9% x x x
Transaminases increased 1% - 8% x x x
Blood alkaline phosphatase increased 8% x x
Hypokalaemia 1% - 18% x
Hypophosphataemia 3% - 28% x x
Unspecified disorder of skin and subcutaneous tissue 0% - 8.72% x x
Pneumonia 4.1% x x x
Dyspepsia 0% - 8% x x x
Renal cyst 0% - 4.07% x x x
Pulmonary embolism 1.2% - 6% x
Syncope 0% - 3% x x
Electrocardiogram QT prolonged 0% - 5% x x x
Electrocardiogram QT corrected interval prolonged 2.9% x
Mediastinal disorder 0.581% - 4.07% x x x
Urinary tract disorder 0% - 4.07% x x
Interstitial lung disease 0.581% - 4.07% x x x
Dyspnoea 1.2% - 2.3% x
Dizziness 0% - 22% x x x
Upper respiratory tract infection 0% - 26% x
Weight decreased 0% - 10% x
Hepatic failure 1% x x x
Gastrointestinal perforation 1% x
Abscess x
Anaemia x
Arrhythmia x
Infection x x
Diplopia x x
Localised oedema x x
Body temperature increased x
Vitreous floaters x x x
Gastrointestinal disorder x x x
Cardiac disorder x x x
Hypoaesthesia x x x
Nervous system disorder x x x
Neuralgia x x x
Paraesthesia x x x
Neuropathy peripheral x x x
Acute respiratory distress syndrome x x x
Sinus bradycardia x x
Burning sensation x
Photopsia x x x
Photophobia x x
Oedema peripheral x x
Hepatic function abnormal x x
Periorbital oedema x x
Peripheral sensory neuropathy x x x
Generalised oedema x x
Gamma-glutamyltransferase increased x x
Muscular weakness x x x
Phosphatase alkaline increased x
Aspartate aminotransferase increased x x
Alanine aminotransferase increased x x
Polyneuropathy x x x
Haemoglobin decreased x
Fatal outcomes x
Visual acuity reduced x x
Dizziness postural x x
Hepatotoxicity x x x
Skin burning sensation x x
Disease progression x
Sepsis x
Hepatobiliary disease x x
Congenital renal cyst x x
Vision blurred x x x
Dysaesthesia x x x
Bradycardia 0% - 5% x x x
Neuropathy x x x
Face oedema x x
Visual disturbance x x
Gait disturbance x x x
Balance disorder x x
Febrile neutropenia x x
Infestation NOS x
Blood and lymphatic system disorders x x
Local swelling x x
Neutrophil count decreased x x
Drug-induced liver injury x
Respiratory failure x
Visual impairment x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

CRIZOTINIB

Side effects:60
Source:FDA Structured Product Label

Chemical Structure: / XALKORI (crizotinib)

Side effects:66
Source:medicines.org.au

crizotinib / crizotinib

Side effects:79
Source:EMA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label