Travoprost
Side effects
Options:
Show MedDRA Preferred Terms
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
|
10
|
11
|
Hyperaemia
|
8.3% - 37.3%
|
|
x
|
|
|
|
|
|
|
x
|
x
|
|
x
|
Iris hyperpigmentation
|
common, 29.5%
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Eye disorder
|
very common
|
|
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
Ocular hyperaemia
|
very common
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Eye pruritus
|
common
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Eye pain
|
common
|
|
|
x
|
x
|
|
|
|
|
|
x
|
x
|
x
|
Eye irritation
|
common
|
|
x
|
|
|
|
|
|
|
|
|
x
|
x
|
Ocular discomfort
|
common
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Discomfort
|
2% - 4.8%
|
2.5%
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Pruritus
|
0.7% - 5.6%
|
1.3%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Skin hyperpigmentation
|
uncommon, common
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Skin discolouration
|
rare, common
|
|
x
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Pain
|
0.3% - 3.5%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Dry eye
|
common, 0.5% - 3.4%
|
2.5%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Sensation of foreign body
|
0.5% - 2.1%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Keratitis
|
uncommon, 0.7% - 1.5%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Lacrimation
|
0.7% - 2.1%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Headache
|
uncommon — 0.3% - 1.4%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Vision blurred
|
uncommon, 0.7% - 2%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Blepharitis
|
uncommon
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Conjunctivitis
|
uncommon
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dermatitis atopic
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Dermatitis contact
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Drug hypersensitivity
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
Seasonal allergy
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Cardiac disorder
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Herpes simplex
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Ophthalmic herpes simplex
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Hypercholesterolaemia
|
uncommon
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
Hypersensitivity
|
uncommon
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Hypotension
|
uncommon
|
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Immune system disorder
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Influenza
|
uncommon
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
|
|
x
|
Macular degeneration
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Metrorrhagia
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Mydriasis
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Nasal congestion
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Nervous system disorder
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Scotoma
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Shoulder pain
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Photophobia
|
uncommon, 0.4% - 2.8%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Cataract
|
uncommon
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
Periorbital oedema
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Peptic ulcer reactivated
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Lacrimation increased
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Unspecified disorder of skin and subcutaneous tissue
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Malaise
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
Visual acuity reduced
|
uncommon
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hair texture abnormal
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Heart rate irregular
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Erythema of eyelid
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Punctate keratitis
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Corneal erosion
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Eye discharge
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Corneal pigmentation
|
uncommon
|
|
x
|
|
|
|
|
|
|
|
|
|
x
|
Growth of eyelashes
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Blood pressure increased
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
Meibomianitis
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Throat irritation
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Eyelids pruritus
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Corneal epithelium defect
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Eyelid margin crusting
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Anterior chamber inflammation
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Pigment dispersion syndrome
|
uncommon
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Dysphonia
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Dark circles under eyes
|
uncommon
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
Iritis
|
uncommon, 0.1% - 0.7%
|
|
x
|
|
|
|
|
|
|
|
|
|
x
|
Asthenia
|
rare, uncommon
|
|
x
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Asthma
|
rare, uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Constipation
|
rare, uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Cough
|
rare, uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Dizziness
|
rare, uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Dysgeusia
|
rare, uncommon
|
|
x
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Dyspnoea
|
rare, uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Endophthalmitis
|
rare, uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Rash
|
rare, uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Gastrointestinal disorder
|
rare, uncommon
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hypertension
|
rare, uncommon
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hypertrichosis
|
rare, uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Palpitations
|
rare, uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Dry mouth
|
rare, uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Madarosis
|
rare, uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Bradycardia
|
rare, uncommon
|
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hair colour changes
|
rare, uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Anterior chamber pigmentation
|
rare, uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Oropharyngeal pain
|
rare, uncommon
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Corneal staining
|
0.1%
|
1.3%
|
x
|
|
|
|
|
x
|
x
|
x
|
|
|
x
|
Asthenopia
|
rare
|
|
|
x
|
x
|
|
|
|
|
|
x
|
x
|
x
|
Infection
|
rare
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Iridocyclitis
|
rare
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Uveitis
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Angiopathy
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Conjunctival oedema
|
rare
|
|
x
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Eczema eyelids
|
rare
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Nasal dryness
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Infestation NOS
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Eye allergy
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Hypoaesthesia eye
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Nasal discomfort
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Conjunctival follicles
|
rare
|
|
x
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Eyelid irritation
|
rare
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Eyelash discolouration
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Eyelash thickening
|
rare
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Abdominal pain
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Angina pectoris
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Anxiety
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
Arthralgia
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Arthritis
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Back pain
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Mental disorder
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Bone disorder
|
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
Bronchitis
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Chest pain
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
Conjunctival disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Conjunctivitis allergic
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Connective tissue disorder
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Depression
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
x
|
Diarrhoea
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Dyspepsia
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Dysuria
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Ectropion
|
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
Oedema
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
Eyelid disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Fatigue
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
Inflammation
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
Keratoconjunctivitis sicca
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Mediastinal disorder
|
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
Musculoskeletal pain
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Nausea
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Pharyngitis
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
Prostatic disorder
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Retinal detachment
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Retinal haemorrhage
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Rhinitis
|
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
|
Sinusitis
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Subconjunctival hemorrhage
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Tachycardia
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Tinnitus
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Erythema
|
|
|
x
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Urinary incontinence
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
Urinary tract infection
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Urinary tract disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Vertigo
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Vitreous detachment
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Photopsia
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Accidental injury
|
|
|
|
|
|
x
|
x
|
|
|
x
|
|
|
|
Retinal pigmentation
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Eyelid oedema
|
|
|
|
|
|
|
|
|
|
|
x
|
|
x
|
Prostatic specific antigen increased
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Scab
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Myalgia
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
Hair growth abnormal
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Tenderness
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Eye swelling
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Macular oedema
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Blood pressure systolic increased
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Blood pressure diastolic decreased
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
Choroidal nevus
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
Halo vision
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Sunken eyes
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Scleral hyperaemia
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Anterior chamber flare
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Anterior chamber cell
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Abnormal sensation in eye
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Asthma aggravated
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
Ear and labyrinth disorders
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Foreign body sensation in eyes
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Eyelid pain
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Conjunctival hyperaemia
|
|
|
|
x
|
x
|
x
|
x
|
|
x
|
|
|
|
x
|
Visual impairment
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
Abnormal vision
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 32 |
Source: | Medsafe |
---|
Side effects: | 35 |
Source: | Health Canada |
---|
Side effects: | 35 |
Source: | Health Canada |
---|
Side effects: | 38 |
Source: | FDA |
---|
Side effects: | 38 |
Source: | FDA |
---|
Side effects: | 39 |
Source: | FDA Structured Product Label |
---|
Side effects: | 40 |
Source: | FDA Structured Product Label |
---|
Side effects: | 41 |
Source: | FDA |
---|
Side effects: | 98 |
Source: | EMA |
---|
Side effects: | 103 |
Source: | EMA |
---|
Side effects: | 135 |
Source: | Medsafe |
---|
Color scheme:
standard – alternative
|
|
100%
|
|
|
75%
|
|
|
50%
|
|
|
10%
|
|
|
frequent (1% to 100%)
|
|
|
infrequent (0.1% to 1%)
|
|
|
rare (<0.1%)
|
|
|
postmarketing
|
|
|
0%
|
|
|
no frequency information
|
|
|
not found on label
|