Search results :

Bupivacaine

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Codes: N01BB01, N01BB10

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13
Gastrointestinal disorder Gastrointestinal disorder 7.37% - 42.3% 13.8% - 39.6% x
Hypotension Hypotension 19.6% - 31% x x x x x x x x x x x x x
Hypotensive x x x x x
Nausea Nausea 2.11% - 40.2% 1.06% - 37.5% x x x x x x x x x x x x x
Nervous system disorder Nervous system disorder 0% - 20.6% 0% - 31.2% x
Anaemia Anaemia 8.17% - 12% x x
Foetal distress syndrome Foetal distress syndrome 5% - 9.63% x
Vomiting Vomiting 2.11% - 27.8% 4.26% - 17.7% x x x x x x x x x x x x x
Procedural pain Postoperative pain 7.27% - 18% x
Procedural pain x
Delayed delivery Delayed delivery 6.29% - 6.84% x
Dizziness Dizziness 0% - 11.3% 0% - 26% x x x x x x x x x x x x x
Syncope 0% - 2.06% 0% x x x x x x x x x
Lightheadedness x x x x
Back pain Back pain 4.19% - 5.7% x x x x x x x x x x x
Headache Headache 0% - 7% 0% - 8.33% x x x x x x x x x x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue 0% - 8.25% 0% - 7.29% x
Pain Pain 3.54% - 8% x
Pruritus Pruritus 0% - 9% 0% - 1.04% x x x x x x x x x
Electrocardiogram abnormal Electrocardiogram abnormal 3.14% - 3.75% x
Body temperature increased Body temperature increased 0% - 17% 0% - 3.19% x x x x x x x x x x
Diplopia Diplopia 2.55% - 3.09% x x x
Abdominal distension Enlargement abdomen 2.65% - 2.95% x
Chills Rigors 2.65% - 2.95% x
Shivering x x
Chills x x x x x x x x
Constipation Constipation 2.06% - 7% 1.04% - 2.13% x x
Pruritus generalised Pruritus generalised 0% - 5.15% 0% - 6.25% x
Hypoaesthesia Hypoaesthesia 1.5% - 3.31% x x
Numbness x x
Flatulence Flatulence 2.36% - 2.43% x
Haemorrhage in pregnancy Haemorrhage in pregnancy 1.77% - 2.65% x
Dyspepsia Dyspepsia 1.96% - 2.43% x
Bradycardia Bradycardia 1.6% - 2.21% x x x x x x x x x x x x
Wound secretion Wound discharge increased 1.38% - 2.87% x
Alanine aminotransferase increased Alanine aminotransferase increased 1.05% - 3.09% 0% - 3.12% x
Tachycardia Tachycardia 1.55% - 3.9% x x x x x x x x x
Abdominal pain Abdominal pain 1.32% - 2.16% x
Gastrointestinal pain Abdominal pain 1.32% - 2.16% x
Body temperature decreased Body temperature decreased 1.32% - 2.16% x
Hypothermia Body temperature decreased 1.32% - 2.16% x
Anal haemorrhage Anal haemorrhage 0% - 3.16% 0% - 4.26% x
Aspartate aminotransferase increased Aspartate aminotransferase increased 0% - 3.09% 0% - 2.08% x
Urine abnormality Urine abnormality 1.32% - 1.77% x
Urine analysis abnormal Urine abnormality 1.32% - 1.77% x
Haematuria Haematuria 1.1% - 1.96% x
Hypertension Hypertension 0.982% - 1.77% x x x x x x x
Lethargy Lethargy 1.3% x
Somnolence Somnolence 0% - 5.15% 0% - 1.04% x x
Drowsiness x x x x x x x x x x x x
Anxiety Anxiety 0.982% - 1.32% x x x x x x x x x x
Apprehension x x
Diarrhoea Diarrhoea 0.982% - 1.32% x
Purpura Purpura 0.883% - 1.38% x
Vascular purpura Purpura 0.883% - 1.38% x
Dyschezia Dyschezia 0% - 2.11% 0% - 5.32% x
Infection Infection 0% - 2.06% 0% - 1.04% x
Fungal infection Fungal infection 0% - 2.06% 0% - 1.04% x
Shock Syncope 0% - 2.06% 0% x x x x x x x x x
Shock x x x x x x x
Syncope Syncope 0% - 2.06% 0% x x x x x x x x x
Loss of consciousness Syncope 0% - 2.06% 0% x x x x x x x x x
Loss of consciousness x x x x x x x x x x x x
Malnutrition Malnutrition 0% - 2.06% 0% - 2.08% x
Decreased appetite Decreased appetite 0% - 2.06% 0% - 2.08% x
Blood creatinine increased Blood creatinine increased 0% - 2.06% 0% x
Infestation Infestation NOS 0% - 2.06% 0% - 1.04% x
Post procedural swelling Post procedural swelling 0% - 2.06% 0% x
Feeling hot Feeling hot 0% - 2.06% 0% x
Sensation of heat x x
Breast pain Breast pain 0.883% - 0.982% x
Cough Cough 0.662% - 1.18% x
Leukocytosis Leukocytosis 0.662% - 1.18% x
Urinary tract infection Urinary tract infection 0.662% - 0.982% x
Urine flow decreased Urine flow decreased 0.662% - 0.982% x
Urinary incontinence Urinary incontinence 0.221% - 1.18% x x x x x x x x x
Rectal discharge Rectal discharge 0% - 1.05% 0% - 3.19% x
Paraesthesia Paraesthesia postmarketing, 0.442% - 1.77% x x x x x x x x x x x x
Anaphylactic shock Anaphylactic shock postmarketing x x
Anaphylactoid reaction x x
Asthenia Asthenia postmarketing x x x x x x
Toxicity to various agents Drug toxicity postmarketing x
Flushing Flushing postmarketing x
Horner's syndrome Horner's syndrome postmarketing x
Miosis Miosis postmarketing x
Priapism Priapism postmarketing x
Convulsion Convulsion postmarketing x x x x x x x x x x x
Hyperhidrosis Sweating postmarketing x
Hyperhidrosis x
Sweating increased x x x x x x x x
Injury Trauma postmarketing x x
Sensory disturbance Sensory disturbance postmarketing x
Cauda equina syndrome Cauda equina syndrome postmarketing x x x x
Paralysis Paralysis postmarketing x x x x x x x x x
Acidosis Acidosis x x x x x x x x x
Angioedema Angioedema x x x x x x x x
Apnoea Apnoea x x x x x x x x
Arachnoiditis Arachnoiditis x x x x x x x
Arrhythmia Arrhythmia x
Arthralgia Arthralgia x
Musculoskeletal discomfort Arthralgia x
Mental disorder Mental disorder x
Bone disorder Bone disorder x
Bronchospasm Bronchospasm x
Cardiac output decreased Cardiac output decreased x x x x x x x x
Cardiovascular disorder Cardiovascular disorder x
Neck pain Neck pain x
Confusional state Confusional state x x x x
Feeling abnormal Confusional state x x x x
Dysphagia Dysphagia x x
Drug hypersensitivity Drug hypersensitivity x
Dysarthria Dysarthria x
Slurred speech x x
Osteoarthritis Dysarthria x
Dyspnoea Dyspnoea x
Oedema Oedema x x x x x x
Extravasation Extravasation x x
Cardiac arrest Cardiac arrest x x x x x x x x x x x
Atrioventricular block Block heart x x x x x x x x x
Cardiac disorder Cardiac disorder x
Hypercapnia Hypercapnia x
Carbon dioxide increased Hypercapnia x
Hyperkalaemia Hyperkalaemia x x
Hypersensitivity Hypersensitivity x x x x x x
Hypocalcaemia Hypocalcaemia x x
Orthostatic hypotension Orthostatic hypotension x
Laryngeal oedema Laryngeal oedema x x x x x x x x
Laryngospasm Laryngospasm x
Meningism Meningism x x x x x x
Meningitis Meningitis x x x x x x x
Meningitis aseptic Meningitis aseptic x x
Nervousness Nervousness x x x x x
Tension Nervousness x x x x x
Sensory loss Numbness x x
Pallor Pallor x
Palpitations Palpitations x
Paraplegia Paraplegia x x x x
Monoplegia Paraplegia x x x x
Diplegia Paraplegia x x x x
Paresis Paresis x x x
Neuropathy peripheral Neuropathy peripheral x
Neuropathy x x x
Supraventricular extrasystoles Supraventricular extrasystoles x
Prurigo Prurigo x
Pulmonary oedema Pulmonary oedema x
Hyperacusis Hyperacusis x
Respiratory failure Respiratory insufficiency x
Respiratory failure x
Respiratory paralysis Respiratory paralysis x x x x x x x x
Sneezing Sneezing x x x x x x x x
Muscle spasms Muscle spasms x x
Tinnitus Tinnitus x x x x x x x x x x x x
Tremor Tremor x x x x x x x x x x x
Erythema Erythema x x x x x x x x x
Urticaria Urticaria x x x x x x x x x x x x x
Ventricular fibrillation Ventricular fibrillation x x x x x x
Ventricular tachycardia Ventricular tachycardia x x x x x x x
Urinary retention Urinary retention x x x x x x x x x x x
Sinus bradycardia Sinus bradycardia x
Ventricular arrhythmia Ventricular arrhythmia x x x x x x x x
Agitation Agitation x x x x x x x x x
Excitement x x x x x x x x x
Oedema peripheral Oedema peripheral x
Hypokinesia Hypokinesia x
Cranial nerve paralysis Cranial nerve paralysis x x x x x x
Musculoskeletal stiffness Neck stiffness x x
Stiffness x
Nuchal rigidity Neck stiffness x x
Depressed level of consciousness CNS depression NOS x x
Swelling face Swelling face x
Ventricular extrasystoles Ventricular extrasystoles x
Muscular weakness Muscular weakness x x
Paraesthesia oral Circumoral paresthesia x
Skin discolouration Skin discolouration x
Respiratory arrest Respiratory arrest x x x x x x x x x x
Anterior spinal artery syndrome Anterior spinal artery syndrome x
Muscle twitching Muscle twitching x x
Cardiac fibrillation Cardiac fibrillation x x
Cold sweat Cold sweat x
Dizziness postural Dizziness postural x
Neurological symptom Neurologic reaction x
Neurotoxicity Neurotoxicity x x
CNS toxicity x x
Respiratory depression Respiratory depression x x x x x x
Pulmonary function test decreased Respiratory depression x x x x x x
Muscle contractions involuntary Muscle contractions involuntary x
Euphoric mood Euphoric mood x x
Vasoconstriction Vasoconstriction peripheral x x
Peripheral nerve injury Peripheral nerve injury x
Extradural abscess Extradural abscess x
Blood bilirubin increased Blood bilirubin increased x
Extrasystoles Extrasystoles x
Anaphylactoid reaction Anaphylactoid reaction x x
Chondrolysis Chondrolysis x
Vision blurred Vision blurred x x x x x x x x x x x x x
Depressed mood Depressed mood x
Dysaesthesia Dysaesthesia x
Spinal anaesthesia Total spinal block x x x x x x
Blood pressure increased Blood pressure increased x
Hypoaesthesia oral Numbness of tongue x x x
Hypoesthesia tongue x x x
Oxygen saturation decreased Oxygen saturation decreased x
Injury associated with device Needle injury x
Anaemia postoperative Anaemia postoperative x
Insomnia Insomnia x
Haemorrhagic anaemia Haemorrhagic anaemia x
Ileus Ileus x
Procedural hypotension Procedural hypotension x
Procedural hypertension Procedural hypertension x
Incision site oedema Incision site oedema x
Procedural nausea Procedural nausea x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

BUPIVACAINE

Side effects:79
Source:FDA Structured Product Label

BUPIVACAINE HYDROCHLORIDE / MARCAINE SPINAL 7.5 MG/ML

Side effects:47
Source:Health Canada

BUPIVACAINE

Side effects:47
Source:FDA Structured Product Label

BUPIVACAINE

Side effects:48
Source:FDA Structured Product Label

Bupivacaine

Side effects:46
Source:FDA Structured Product Label

Bupivacaine

Side effects:46
Source:FDA Structured Product Label

Bupivacaine

Side effects:48
Source:FDA Structured Product Label

BUPIVACAINE HYDROCHLORIDE / SENSORCAINE 0.25%

Side effects:54
Source:Health Canada

Levobupivacaine Injection / CHIROCAINE

Side effects:94
Source:medicines.org.au

Color scheme:

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    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label