Search results :

Buprenorphine

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Codes: N02AE01, N07BC01

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11
Headache Headache 3% - 36.4% 5% - 22.4% x x x x x x x x x x x
Insomnia Insomnia 3% - 28.2% 2% - 15.9% x x x x x x x x x x
Pain Pain 11.7% - 26.3% 6.54% - 18.7% x x x x x
Withdrawal syndrome Withdrawal syndrome 18.4% - 25.2% 37.4% x x x x x x x x
Infection Infection 5.6% - 22.1% 6.54% x x x x x x x x x
Asthenia Asthenia 4.85% - 15.6% 6.54% x x x x x x x x x x
Fatigue 5% 1% x x x x x
Back pain Back pain 3% - 16.1% 2% - 11.2% x x x x x x x x x
Hyperhidrosis Sweating 12.6% - 14% 10.3% x x x x x x x x
Hyperhidrosis 4% 1% x x x
Anxiety Anxiety 10.8% - 13.8% x x x x x x x x
Nausea Nausea 6% - 23% 6% - 11.2% x x x x x x x x x x x
Depression Depression 8.89% - 13.4% x x x x
Rhinitis Rhinitis 4.7% - 14.7% 13.1% x x x x x x x x x x
Application site pruritus Application site pruritus 4% - 15% 7% - 12% x x x
Constipation Constipation 3% - 14.4% 1% - 5% x x x x x x x x x x x
Nervousness Nervousness 5.38% - 7.18% x x x x x x x x x
Tension Nervousness 5.38% - 7.18% x x x x x x x x x
Influenza Influenza 2.17% - 10.2% x x x x x x x
Application site erythema Application site erythema 3% - 10% 2% x x x
Dry mouth Dry mouth 6% - 7% 2% x x x x x
Application site rash Application site rash 3% - 9% 6% x x x x
Chills Chills 4.84% - 7.77% 7.48% x x x x x x x x x x
Rigors x
Vomiting Vomiting 2% - 11% 1% - 4.67% x x x x x x x x x x x
Somnolence Somnolence 2% - 14% 2% - 5% x x x x x x x x
Fatigue Fatigue 5% 1% x x x x x
Diarrhoea Diarrhoea 2.21% - 10.3% 2% - 15% x x x x x x x x x x x
Dizziness Dizziness 2% - 16% 1% - 8% x x x x x x x x x
Syncope x x x x
Vasodilation procedure Vasodilation 3.88% - 9.3% 6.54% x x x x x x
Pharyngitis Pharyngitis 3.23% - 4.97% x x x x
Dyspepsia Dyspepsia 2.15% - 5.56% 3% x x x x x x x x x
Heartburn x
Cough Cough 2.21% - 6.11% x x x x x x x x
Dyspnoea Dyspnoea 3% 1% x x x x x
Pain in extremity Pain in extremity 3% 2% x x x
Pruritus Pruritus 3% - 4% 0% - 1% x x x x x
Urinary tract infection Urinary tract infection 3% 2% x x x
Oedema peripheral Oedema peripheral 3% - 7% 1% - 3% x x x x
Joint swelling Joint swelling 3% 1% x x x
Body temperature increased Body temperature increased 1.08% - 5.52% x x x x x x x x
Decreased appetite Anorexia 2% 1% x x x x
Appetite absent x
Arthralgia Arthralgia 2% 2% x x x
Musculoskeletal discomfort Arthralgia 2% 2% x x x
Myalgia x x x x
Confusional state Confusional state 2% 3% x x x x x
Feeling abnormal Confusional state 2% 3% x x x x x
Malaise x x x x x
Dermatitis Rash 2% 1% x x x x x
Rash Rash 2% 1% x x x x x
Hypoaesthesia Hypoaesthesia 2% 1% x x x x
Numbness x
Paraesthesia Paraesthesia 2% 1% x x x x x
Tremor Tremor 2% 1% x x x x x
Abdominal discomfort Upset stomach 2% 0% - 1% x x x
Application site irritation Application site irritation 2% - 6% x x x
Abscess Abscess 1.1% - 4.89% x x x x
Abdominal distension Abdominal distension x x x
Abdominal pain Abdominal pain x x x x
Gastrointestinal pain Abdominal pain x x x x
Amblyopia Amblyopia x
Anaphylactic shock Anaphylactic shock x
Angina pectoris Angina pectoris x x x x
Angioedema Angioedema x x x x
Apnoea Apnoea x
Mental disorder Mental disorder x x x x
Breast disorder Breast disorder x
Bronchospasm Bronchospasm x
Bronchitis Bronchitis x x x
Neck pain Neck pain x x x
Chest pain Chest pain x x x x
Coma Coma x
Conjunctivitis Conjunctivitis x
Connective tissue disorder Connective tissue disorder x x x x
Cyanosis Cyanosis x
Libido decreased Libido decreased x x x x
Disturbance in sexual arousal Libido decreased x x x x
Dysphagia Dysphagia x x x x
Dehydration Dehydration x x x x
Depersonalisation Depersonalisation x x x x x
Dermatitis contact Dermatitis contact x x x x
Diplopia Diplopia x
Diverticulitis Diverticulitis x x x x
Drug hypersensitivity Drug hypersensitivity x x x
Dysarthria Dysarthria x x x x
Slurred speech x
Osteoarthritis Dysarthria x x x x
Dysgeusia Dysgeusia x x x x
Dysmenorrhoea Dysmenorrhoea x
Ear pain Ear pain x
Oedema Oedema x
Eye disorder Eye disorder x
Muscle contractions involuntary Fasciculation x
Flatulence Flatulence x x x x x
Flushing Flushing x x x x x
Gastrointestinal disorder Gastrointestinal disorder x x x x
Hallucination Hallucination x x x x x
Cardiac disorder Cardiac disorder x
Hiccups Hiccups x x x x
Hypersensitivity Hypersensitivity x x x x x
Hypertension Hypertension x x x x x
Hyperventilation Hyperventilation x x x x
Hypotension Hypotension x x x x x
Hypotensive x x x
Orthostatic hypotension Orthostatic hypotension x x x x
Immune system disorder Immune system disorder x
Inflammation Inflammation x
Lethargy Lethargy x
Mediastinal disorder Mediastinal disorder x x x x
Miosis Miosis x x x x x
Muscle spasms Cramp muscle x
Muscle spasms x x x x
Musculoskeletal pain Musculoskeletal pain x x x
Nasopharyngitis Nasopharyngitis x x x
Nervous system disorder Nervous system disorder x x x x
Nightmare Nightmare x x x x
Sensory loss Numbness x
Pallor Pallor x
Palpitations Palpitations x x x x
Psychotic disorder Psychotic disorder x x x x x
Convulsion Convulsion x x x x x
Shock Shock x
Syncope x x x x
Sinusitis Sinusitis x x x
Syncope Syncope x x x x
Loss of consciousness Syncope x x x x
Loss of consciousness x x x
Tachycardia Tachycardia x x x x x
Tinnitus Tinnitus x x x x x
Erythema Erythema x
Upper respiratory tract infection Upper respiratory tract infection x x x
Urinary incontinence Urinary incontinence x x x x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Urticaria Urticaria x x x x x
Angiopathy Angiopathy x x x x
Vertigo Vertigo x x x x x
Poor quality sleep Wakefulness x
Weight decreased Weight decreased x x x x
Wheezing Wheezing x x x x
Urinary retention Urinary retention x x x x x
Agitation Agitation x x x x x
Apathy Apathy x x x
Flat affect Apathy x x x
Mood swings Mood swings x
Affect lability Mood swings x
Affect lability x x x x
Migraine Migraine x x x x
Application site reaction Application site reaction x
Depressed level of consciousness CNS depression NOS x
Depressed level of consciousness x x x
Injection site reaction Injection site reaction x
Injury Accidental injury x x x x
Muscular weakness Muscular weakness x x x x
Biliary colic Biliary colic x
Alanine aminotransferase increased Alanine aminotransferase increased x x x
Dry skin Dry skin x x x x
Urinary hesitation Urinary hesitation x x x x
Drug withdrawal syndrome Drug withdrawal syndrome x x x
Eyelid oedema Eyelid oedema x
Malnutrition Malnutrition x x x x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x x x x
Malaise Malaise x x x x x
Discomfort Malaise x x x x x
Ill-defined disorder Malaise x x x x x
Myalgia Myalgia x x x x
Abdominal pain upper Abdominal pain upper x x x
Retching Retching x
Disorientation Disorientation x x x
Disturbance in attention Disturbance in attention x x x
Cerebration impaired x
Dysphoria Dysphoria x
Memory impairment Memory impairment x x x x
Respiratory depression Respiratory depression x x x x
Pulmonary function test decreased Respiratory depression x x x x
Euphoric mood Euphoric mood x x x x x
Sedation Sedation x
Mental disability Cerebration impaired x
Mental disability x x x
Swollen tongue Swollen tongue x
Rash pustular Pustule x
Atrioventricular block second degree Wenckebach phenomenon x
Hepatobiliary disease Hepatobiliary disease x
Balance disorder Dysequilibrium x
Dry eye Dry eye x x x x
Vision blurred Vision blurred x x x x x
Depressed mood Depressed mood x x x
Feeling hot Warmth x
Bradycardia Bradycardia x x x x
Pruritus generalised Pruritus generalised x x x
Respiratory distress Respiratory distress x x x
Blood pressure increased Blood pressure increased x x
Coordination abnormal Coordination abnormal x x x x
Influenza like illness Influenza like illness x
Face oedema Face oedema x x x x
Visual impairment Visual disturbance x x x x
Altered state of consciousness Depressed level of consciousness x x x
Asthma Asthma aggravated x x x x
Sexual dysfunction Sexual dysfunction x x x x
Gait disturbance Gait disturbance x x x
Menopausal symptoms Hot flush x x x
Hot flush Hot flush x x x
Drug interaction Drug interaction x
Cardiovascular disorder Unspecified circulatory system disorder x
Infestation Infestation NOS x x x
Sleep disorder Sleep disorder x
Oropharyngeal swelling Oropharyngeal swelling x
Electrocardiogram QT prolonged Electrocardiogram QT corrected interval prolonged x x x
Mental status changes Mental status changes x x x
Laryngeal pain Pharyngolaryngeal pain x x x
Respiratory failure Respiratory failure x x x x
Hypoventilation x x x x
Ileus Ileus x x x x
Respiratory disorder Respiration abnormal x x x
Respiration abnormal Respiration abnormal x x x
Mental retardation Mental disability x x x
Hypoxia Hypoventilation x x x x
Hypoventilation Hypoventilation x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

BUPRENORPHINE

Side effects:15
Source:FDA Structured Product Label

BUPRENORPHINE

Side effects:15
Source:FDA Structured Product Label

BUPRENORPHINE

Side effects:25
Source:FDA Structured Product Label

BUPRENORPHINE

Side effects:26
Source:FDA Structured Product Label

buprenorphine

Side effects:26
Source:FDA Structured Product Label

BUPRENORPHINE

Side effects:26
Source:FDA Structured Product Label

Buprenorphine

Side effects:58
Source:FDA Structured Product Label

buprenorphine

Side effects:137
Source:FDA Structured Product Label

buprenorphine

Side effects:136
Source:FDA Structured Product Label

buprenorphine

Side effects:138
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label