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Trabectedin

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: L01CX01

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1
Pancytopenia Pancytopenia 1.5% - 1.8% x
Agranulocytosis Agranulocytosis 1.5% x
Pulmonary embolism Pulmonary embolism 1.2% x
Pulmonary oedema Pulmonary oedema 1% x
Hepatotoxicity Hepatotoxicity 1% x
Left ventricular dysfunction Left ventricular dysfunction 1% x
Neutropenic sepsis Neutropenic sepsis 1% x
Neutropenic infection Neutropenic infection 1% x
Abdominal pain Abdominal pain x
Gastrointestinal pain Abdominal pain x
Alopecia Alopecia x
Anaemia Anaemia x
Anemic x
Decreased appetite Anorexia x
Decreased appetite x
Arthralgia Arthralgia x
Musculoskeletal discomfort Arthralgia x
Myalgia x
Asthenia Asthenia x
Fatigue x
Back pain Back pain x
Mental disorder Mental disorder x
Infection Infection x
Connective tissue disorder Connective tissue disorder x
Constipation Constipation x
Cough Cough x
Dehydration Dehydration x
Diarrhoea Diarrhoea x
Dizziness Dizziness x
Syncope x
Dysgeusia Dysgeusia x
Dyspepsia Dyspepsia x
Dyspnoea Dyspnoea x
Oedema Oedema x
Dermatitis Rash x
Rash Rash x
Extravasation Extravasation x
Fatigue Fatigue x
Body temperature increased Body temperature increased x
Flushing Flushing x
Gastrointestinal disorder Gastrointestinal disorder x
Headache Headache x
Haemorrhage Haemorrhage x
Haemoglobin Haemorrhage x
Hepatomegaly Hepatomegaly x
Hyperbilirubinaemia Hyperbilirubinaemia x
Hypersensitivity Hypersensitivity x
Hypokalaemia Hypokalaemia x
Hypotension Hypotension x
Jaundice Jaundice x
Leukopenia Leukopenia x
Mediastinal disorder Mediastinal disorder x
Multi-organ failure Multi-organ failure x
Musculoskeletal pain Musculoskeletal pain x
Nausea Nausea x
Necrosis Necrosis x
Nervous system disorder Nervous system disorder x
Neutropenia Neutropenia x
Paraesthesia Paraesthesia x
Rhabdomyolysis Rhabdomyolysis x
Septic shock Septic shock x
Stomatitis Stomatitis x
Shock Syncope x
Syncope Syncope x
Loss of consciousness Syncope x
Thrombocytopenia Thrombocytopenia x
Angiopathy Angiopathy x
Vomiting Vomiting x
Weight decreased Weight decreased x
Hepatic failure Hepatic failure x
Oedema peripheral Oedema peripheral x
Peripheral sensory neuropathy Peripheral sensory neuropathy x
Gamma-glutamyltransferase increased Gamma-glutamyltransferase increased x
Injection site reaction Injection site reaction x
Aspartate aminotransferase increased Aspartate aminotransferase increased x
Alanine aminotransferase increased Alanine aminotransferase increased x
Liver injury Liver injury x
Traumatic liver injury Liver injury x
Malnutrition Malnutrition x
Skin hyperpigmentation Skin hyperpigmentation x
Skin disorder Unspecified disorder of skin and subcutaneous tissue x
Myalgia Myalgia x
Abdominal pain upper Abdominal pain upper x
Blood creatinine increased Blood creatinine increased x
Sepsis Sepsis x
Hepatobiliary disease Hepatobiliary disease x
Mucosal inflammation Mucosal inflammation x
Hepatic pain Hepatic pain x
Febrile neutropenia Febrile neutropenia x
Infestation Infestation NOS x
Blood alkaline phosphatase increased Blood alkaline phosphatase increased x
Blood creatine phosphokinase increased Blood creatine phosphokinase increased x
Blood albumin decreased Blood albumin decreased x
Bilirubin conjugated increased Bilirubin conjugated increased x
Insomnia Insomnia x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

trabectedin / trabectedin

Side effects:87
Source:EMA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label