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Deprenyl

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: N04BD01

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12
Application site reaction Application site reaction 24% 12% x x x
Nausea Nausea 10% - 11% 3% - 9% x x x x x x x x x x x
Pain Pain 8% 7% x x x x x x x x x x
Ache 1% 0% x x x x x x
Generalized aching x x x x x
Dizziness Dizziness postmarketing, 7% - 11% 1% - 8% x x x x x x x x x x x
Syncope postmarketing — 7% 1% x x x x x x x x x x x
Lightheadedness 7% 1% x x x x x x
Rhinitis Rhinitis 7% 6% x x x x
Shock Syncope postmarketing — 7% 1% x x x x x x x x x x x
Shock x
Syncope Syncope postmarketing — 7% 1% x x x x x x x x x x x
Loss of consciousness Syncope postmarketing — 7% 1% x x x x x x x x x x x
Skin disorder Skin disorder 6% 2% x x
Unspecified disorder of skin and subcutaneous tissue x
Amnesia Amnesia frequent x x x
Decreased appetite Anorexia frequent x x x x x x x x x x
Decreased appetite x x x x x
Bronchitis Bronchitis frequent x x x x
Neck pain Neck pain frequent x x x x
Chest pain Chest pain frequent, 2% 0% x x x x x x
Precordial pain x
Constipation Constipation frequent, 4% 0% x x x x x x x x x x x x
Dysgeusia Dysgeusia frequent x x x x x x x x x x
Dysmenorrhoea Dysmenorrhoea frequent x x x
Ecchymosis Ecchymosis frequent, 2% 0% x x x x x
Flatulence Flatulence frequent, 2% 1% x x x x x
Gastroenteritis Gastroenteritis frequent x x x x
Hypertension Hypertension frequent, 3% 2% x x x x x x x x x x x x
Metrorrhagia Metrorrhagia frequent x x x
Paraesthesia Paraesthesia frequent x x x x
Pruritus Pruritus frequent x x x x x
Stomatitis Stomatitis 5% 4% x x
Hyperhidrosis Sweating postmarketing, frequent x x x x x x
Sweating increased x x x x x
Tinnitus Tinnitus frequent x x x x x x x x x x
Pollakiuria Pollakiuria frequent x x x x x x x x x
Micturition urgency infrequent x x x x
Vomiting Vomiting frequent, 3% 0% x x x x x x x x x x x
Agitation Agitation postmarketing, frequent x x x x x x x x x x x
Hyperkinesia infrequent x x x x x x
Oedema peripheral Oedema peripheral frequent x x x x x x x x
Ankle edema x x x x x x
Myalgia Myalgia frequent, 3% 0% x x x x x
Musculoskeletal discomfort Myalgia frequent, 3% 0% x x x x x
Arthralgia infrequent x x x x
Thinking abnormal Thinking abnormal postmarketing, frequent x x x x x
Mental disability Thinking abnormal postmarketing, frequent x x x x x
Cough Cough increased frequent x x x
Abdominal pain Abdominal pain 4% 2% x x x x x x x x x
Gastrointestinal pain Abdominal pain 4% 2% x x x x x x x x x
Dyspepsia Dyspepsia 4% - 5% 3% x x x x x x
Heartburn x x x x x
Dermatitis Rash 4% 1% - 2% x x x x x x x x x x x
Rash Rash 4% 1% - 2% x x x x x x x x x x x
Confusional state Confusional state postmarketing — 3% 0% x x x x x x x x x x x
Feeling abnormal Confusional state postmarketing — 3% 0% x x x x x x x x x x x
Malaise rare, 0% 1% x x x x x x x x x x
Hallucination Hallucination postmarketing, 3% - 4% 1% - 2% x x x x x x x x x
Pharyngitis Pharyngitis 3% - 4% 2% x x x x x
Sinusitis Sinusitis 3% 1% x x x x
Dry mouth Dry mouth postmarketing, 3% - 8% 1% - 6% x x x x x x x x x x x x
Urinary tract infection Urinary tract infection infrequent, frequent x x x
Depression Depression 2% 1% x x x
Dyskinesia Dyskinesia postmarketing, 2% - 6% 3% - 5% x x x x x x x x x
Movements involuntary x x x x x x
Headache Headache postmarketing, 2% - 18% 1% - 17% x x x x x x x x x x x x
Hypokalaemia Hypokalaemia 2% 0% x x
Tooth disorder Tooth disorder 2% 1% x x
Abnormal dreams Vivid dreams 2% 0% x x x x x x
Abnormal dreams x
Somnolence Somnolence postmarketing, 3% 2% x x x x x
Drowsiness x x x x x x
Anxiety Anxiety postmarketing, 1% 1% x x x x x x x x x x
Diarrhoea Diarrhoea 1% - 9% 0% - 7% x x x x x x x x x x x x
Pain in extremity Leg pain 1% 0% x x x x x x
Lethargy Lethargy 1% 0% x x x x x x
Back pain Low back pain 1% 0% x x x x x x
Back pain x x x x x x x x x
Palpitations Palpitations 1% 0% x x x x x x x x x
Weight decreased Weight decreased 1% 0% x x x x x x x x x
Urinary retention Urinary retention 1% 0% x x x x x x
Tension Tension 1% 1% x x x x x x
Nervousness postmarketing x x x x x x x x x x
Insomnia Insomnia postmarketing, 1% - 12% 1% - 7% x x x x x x x x x x x x
Ejaculation disorder Abnormal ejaculation 1% 0% x x x
Erectile dysfunction Erectile dysfunction 0.7% 0.4% x x x
Amenorrhoea Amenorrhoea infrequent x x x
Arthralgia Arthralgia infrequent x x x x
Arthritis Arthritis infrequent x x x x
Asthma Asthma infrequent x x x x x x x x x
Atrial fibrillation Atrial fibrillation infrequent x x x x
Bacterial infection Bacterial infection infrequent x x x
Benign neoplasm of skin Benign neoplasm of skin infrequent x x x x
Vulvovaginal candidiasis Vaginal moniliasis infrequent x x x
Vulvovaginal mycotic infection Vaginal moniliasis infrequent x x x
Colitis Colitis infrequent x x x x
Conjunctivitis Conjunctivitis infrequent x x x x
Cystitis Cystitis infrequent x x x x
Bladder pain Cystitis infrequent x x x x
Cystitis noninfective Cystitis infrequent x x x x
Dysphagia Dysphagia infrequent, 2% 1% x x x x x x x x x x
Dehydration Dehydration infrequent x x x x
Dental caries Dental caries infrequent x x x
Depersonalisation Depersonalisation infrequent x x x
Dermatitis contact Dermatitis contact infrequent x x x x
Fungal skin infection Fungal skin infection infrequent x x x x
Dyspnoea Dyspnoea infrequent, 3% 0% x x x x x x x x x x x
Dysuria Dysuria infrequent x x x
Urination impaired infrequent x x x x
Strangury x
Ear pain Ear pain infrequent x x x
Oedema Oedema infrequent x x x x x
Eructation Eructation infrequent x x x x
Body temperature increased Body temperature increased infrequent x x x x x
Flank pain Flank pain infrequent x x x x
Gastritis Gastritis infrequent x x x x
Glossitis Glossitis infrequent x x x
Haematuria Haematuria infrequent x x x
Hernia Hernia infrequent x x x x
Herpes simplex Herpes simplex infrequent x x x x
Herpes zoster Herpes zoster infrequent x x x x
Hostility Hostility infrequent x x x
Hypercholesterolaemia Hypercholesterolaemia infrequent x x x
Hyperaesthesia Hyperaesthesia infrequent x x x
Hyperglycaemia Hyperglycaemia infrequent x x x x x
Hyponatraemia Hyponatraemia infrequent x x x x
Libido increased Libido increased postmarketing, infrequent x x x x
Disturbance in sexual arousal Libido increased postmarketing, infrequent x x x x
Libido decreased 0% - 0.7% 0% - 0.2% x x x
Arthropathy Arthropathy infrequent x x x x
Osteoarthritis Arthropathy infrequent x x x x
Nephrolithiasis Calculus of kidney infrequent x x x x
Laryngospasm Laryngospasm infrequent x x x
Muscle spasms Cramps of lower extremities infrequent, 3% 1% x x x x x
Generalised spasm infrequent x x x
Cramp muscle x x x x x
Breast pain Breast pain infrequent x x x
Melaena Melaena infrequent x x x
Menorrhagia Menorrhagia infrequent x x x
Hypertonia Hypertonia postmarketing, infrequent x x x x x
Fungal infection Fungal infection infrequent x x x x
Myoclonus Myoclonus infrequent x x x x x x x
Neoplasm Neoplasm infrequent x x x x
Neurosis Neurosis infrequent x x x
Otitis media Otitis media infrequent x x x
Pelvic pain Pelvic pain infrequent x x x
Tooth abscess Abscess periodontal infrequent x x x
Pneumonia Pneumonia infrequent x x x x
Polyuria Polyuria infrequent x x x
Urine output increased Polyuria infrequent x x x
Salivary hypersecretion Salivary hypersecretion infrequent x x x x
Suicide attempt Suicide attempt infrequent x x x
Tachycardia Tachycardia infrequent x x x x x x x x
Tenosynovitis Tenosynovitis infrequent x x x x
Thirst Thirst infrequent x x x
Tongue disorder Tongue disorder infrequent x x x
Tongue oedema infrequent x x x x
Tremor Tremor postmarketing — 3% 1% x x x x x x x x x x x x
Unintended pregnancy Unintended pregnancy infrequent x x x
Urticaria Urticaria infrequent x x x
Vaginal inflammation Vaginal inflammation infrequent x x x
Vaginal infection Vaginal inflammation infrequent x x x
Vertigo Vertigo postmarketing, infrequent x x x x x x x x x x
Viral infection Viral infection infrequent x x x x
Peripheral vascular disorder Peripheral vascular disorder infrequent x x x
Chills Chills infrequent x x x x x x x x
Micturition urgency Micturition urgency infrequent x x x x
Mood swings Mood swings infrequent x x x x x x x x x
Affect lability Mood swings infrequent x x x x x x x x x
Migraine Migraine infrequent x x x x x x x x x
Musculoskeletal stiffness Neck stiffness infrequent x x x x x x x x
Nuchal rigidity Neck stiffness infrequent x x x x x x x x
Alcohol intolerance Alcohol intolerance infrequent x x x
Generalised oedema Generalised oedema infrequent x x x
Fluid retention Generalised oedema infrequent x x x
Tongue oedema Tongue oedema infrequent x x x x
Skin hypertrophy Skin hypertrophy infrequent x x x x
Injury Intentional injury infrequent x x x
Accidental injury x x x x
Injury x
Liver function test abnormal Liver function test abnormal infrequent x x x x
Mania Manic psychosis postmarketing, infrequent x x x x
Eye pain Eye pain infrequent x x x
Paranoia Paranoid reaction postmarketing, infrequent x x x x x
Paraesthesia oral Circumoral paresthesia infrequent x x x
Rash pustular Vesiculobullous rash infrequent x x x
Dermatitis bullous Vesiculobullous rash infrequent x x x
Aspartate aminotransferase increased Aspartate aminotransferase increased infrequent x x x x
Alanine aminotransferase increased Alanine aminotransferase increased infrequent x x x x
Dry skin Dry skin infrequent x x x x
Photosensitivity reaction Photosensitivity reaction infrequent x x x x
Photosensitivity x x x x x
Muscle twitching Muscle twitching infrequent x x x x x x x
Increased appetite Increased appetite infrequent x x x
Euphoric mood Euphoric mood infrequent x x x x
Dry eye Dry eye infrequent x x x x
Rash maculo-papular Rash maculo-papular infrequent x x x
Hyperkinesia Hyperkinesia infrequent x x x x x x
Lymphadenopathy Lymphadenopathy infrequent x x x
Face oedema Face oedema infrequent x x x x
Muscular weakness Myasthenia infrequent x x x x x
Muscular weakness x
Breast neoplasm Breast neoplasm infrequent x x x
Parosmia Parosmia infrequent x x x
Vaginal haemorrhage Vaginal haemorrhage infrequent x x x
Libido decreased Libido decreased 0% - 0.7% 0% - 0.2% x x x
Anorgasmia Anorgasmia 0.2% 0% x x x x x x x
Ataxia Ataxia postmarketing — 3% 1% x x x x x x
Mental disorder Mental disorder postmarketing x x x x
Candida infection Candida infection rare x x x
Coma Coma postmarketing x x
Delirium Delirium postmarketing x
Delirium toxic x
Eczema Eczema rare x x x x
Epistaxis Epistaxis rare x x x x
Flushing Flushing postmarketing x
Gastrointestinal neoplasm Gastrointestinal neoplasm rare x x x
Breath odour Breath odour rare x x x
Heat stroke Heat stroke rare x x x
Hyperbilirubinaemia Hyperbilirubinaemia rare x x x
Impulse-control disorder Impulse-control disorder postmarketing x
Renal failure chronic Renal failure chronic postmarketing x x x x
Laryngitis Laryngitis rare x x x
Leukocytosis Leukocytosis rare x x x x
Leukopenia Leukopenia rare x x x
Mydriasis Mydriasis rare x x x
Myocardial infarction Myocardial infarction rare x x x x x
Acute coronary syndrome Myocardial infarction rare x x x x x
Nervous system disorder Nervous system disorder postmarketing x
Nervousness Nervousness postmarketing x x x x x x x x x x
Neuroleptic malignant syndrome Neuroleptic malignant syndrome postmarketing x
Nightmare Nightmare postmarketing x x x x x x
Osteoporosis Osteoporosis rare x x x
Otitis externa Otitis externa rare x x x x
Petechiae Petechiae rare x x x
Psychotic disorder Psychotic disorder postmarketing x x x
Scotoma Scotoma rare x x x
Convulsion Convulsion postmarketing x x x x x x
Sleep disorder Sleep disturbance postmarketing x x x x x x
Sleep disorder postmarketing x x
Yawning Yawning rare x x x
Skin odour abnormal Body odor rare x x x
Blood alkaline phosphatase increased Phosphatase alkaline increased rare x x x
Muscle contractions involuntary Muscle contractions involuntary postmarketing x
Rectal haemorrhage Rectal haemorrhage rare x x x x x x x x
Hypoglycaemia Hypoglycemic reaction rare x x x
Hypoglycaemia x x
Compulsions Compulsions postmarketing x x
Infection parasitic Infection parasitic rare x x x
Aggression Aggressive reaction postmarketing x
Albuminuria Albuminuria x
Alopecia Alopecia infrequent, 0% 1% x x x x x x x x x x
Amblyopia Amblyopia x
Anaemia Anaemia infrequent, 0% 1% x x x x x x x x x x
Angina pectoris Angina pectoris x x
Angina pectoris aggravated x x x x x x
Aphasia Aphasia x
Apraxia Apraxia x x x x x
Arrhythmia Arrhythmia x x x x x x x
Asthenia Asthenia x x x x x x x x x
Fatigue x x x x x x
Atrial flutter Atrial flutter x
Blepharospasm Blepharospasm x x x x x
Bruxism Bruxism x x x x
Bursitis Bursitis x
Cardiovascular disorder Cardiovascular disorder x
Cellulitis Cellulitis x
Cerebrovascular disorder Cerebrovascular disorder x
Cheilitis Cheilitis x
Cholecystitis Cholecystitis x
Cholelithiasis Cholelithiasis x
Chorea Chorea x x x x x x
Infection Infection x x x
Cyanosis Cyanosis x
Deafness Deafness x
Delusion Delusion x x x x x x
Diabetes mellitus Diabetes mellitus x
Diplopia Diplopia x x x x x x
Eosinophilia Eosinophilia x
Epididymitis Epididymitis x
Oesophagitis Oesophagitis x
Eye haemorrhage Eye haemorrhage x
Fatigue Fatigue x x x x x x
Gastrointestinal disorder Gastrointestinal disorder x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x x x x x
Gingivitis Gingivitis x
Glaucoma Glaucoma x
Gout Gout x
Cardiac arrest Cardiac arrest x
Cardiomegaly Cardiomegaly x
Cardiac failure congestive Cardiac failure congestive x
Blood disorder Blood disorder x
Haematoma Haematoma x x x x x
Subdural haematoma Subdural haematoma x
Hepatitis Hepatitis x
Hiccups Hiccups x x
Hyperkalaemia Hyperkalaemia x
Hyperlipidaemia Hyperlipidaemia x
Hypersensitivity Hypersensitivity x
Hypoproteinaemia Hypoproteinaemia x
Hypotension Hypotension x x x x x x x x
Orthostatic hypotension Orthostatic hypotension x x x x x x x x x
Illusion Illusion x
Influenza Influenza x x x
Intestinal obstruction Intestinal obstruction x
Irritability Irritability x x x x x
Myeloid leukaemia Myeloid leukaemia x
Acute leukaemia Myeloid leukaemia x
Malignant melanoma Malignant melanoma x
Melanoma skin x
Hypotonia Hypotonia x
Muscle relaxant therapy Hypotonia x
Myopathy Myopathy x
Neuralgia Neuralgia x
Neuritis Neuritis x
Neuropathy peripheral Neuritis x
Neuropathy x
Hypoaesthesia Numbness x x x x x
Sensory loss Numbness x x x x x
Nocturia Nocturia x x x x x
Ovarian disorder Ovarian disorder x
Pallor Pallor x
Peptic ulcer Peptic ulcer x
Personality disorder Personality disorder x
Pleural effusion Pleural effusion x
Pneumothorax Pneumothorax x
Pulmonary oedema Pulmonary oedema x
Retinal artery occlusion Retinal artery occlusion x
Retinal detachment Retinal detachment x
Seborrhoeic dermatitis Seborrhoeic dermatitis x
Congenital skin disorder Congenital skin disorder x
Skin ulcer Skin ulcer x
Superinfection Superinfection x
Supraventricular tachycardia Supraventricular tachycardia x x
Thrombocytopenia Thrombocytopenia x
Trismus Trismus x
Ulcer Ulcer x x x x
Erythema Erythema x x x
Urinary incontinence Urinary incontinence x
Micturition disorder Micturition disorder x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Angiopathy Angiopathy x x
Vasodilation procedure Vasodilation x
Weight increased Weight increased x x x
Urogenital disorder Urogenital disorder x
Central nervous system neoplasm Central nervous system neoplasm x
Encephalopathy Encephalopathy x
Sinus bradycardia Sinus bradycardia x x x x x x
Atrioventricular block first degree Atrioventricular block first degree x
Akinesia Akinesia x
Apathy Apathy x x x x x
Flat affect Apathy x x x x x
Fall Fall x x x x x x
Hyperphosphataemia Hyperphosphataemia x
Hypokinesia Hypokinesia x
Cataract Cataract specified x
Red blood cell sedimentation rate increased Red blood cell sedimentation rate increased x
Gamma-glutamyltransferase increased Gamma-glutamyltransferase increased x
Myocardial ischaemia Myocardial ischaemia x
Opisthotonus Opisthotonus x
Bone pain Bone pain x
Platelet disorder Abnormal platelets x
Hyporeflexia Hyporeflexia x
Skin discolouration Skin discolouration x
Tendon rupture Tendon rupture x
Oesophageal ulcer Oesophageal ulcer x
Urinary hesitation Urinary hesitation x x x x x
Accommodation disorder Accommodation disorder x
Malnutrition Malnutrition x x x
Prostatic specific antigen increased Prostatic specific antigen increased x
Pseudolymphoma Pseudolymphoma x
Malaise Malaise rare, 0% 1% x x x x x x x x x x
Discomfort Malaise rare, 0% 1% x x x x x x x x x x
Ill-defined disorder Malaise rare, 0% 1% x x x x x x x x x x
Parkinsonian gait Festinating gait x x x x x
Disorientation Disorientation x x x x x
Bradykinesia Bradykinesia x x x x x x
Hallucination, visual Hallucination, visual x
Memory impairment Memory impairment x x x x
Respiratory depression Respiratory depression x
Pulmonary function test decreased Respiratory depression x
Joint swelling Ankle edema x x x x x x
Grimacing Grimacing x x x x x
Personality change Personality change x x x x x
Strangury Strangury x
Ventricular extrasystoles Ventricular bigeminy x
Extrasystoles Ventricular bigeminy x
Hepatobiliary disease Hepatobiliary disease x
Vision blurred Vision blurred x x x x x
Hypovitaminosis Avitaminosis x
Cold sweat Sticky skin x
Sticky skin Sticky skin x
Epigastric discomfort Gastric irritation x
Hyperpyrexia Hyperpyrexia x x
Heart rate irregular Pulse irregular x
Mean arterial pressure Mean arterial pressure x x x
Bradycardia Bradycardia x
Energy increased Energy increased x x x x
Blindness Blindness x
Dementia Dementia x
Coordination abnormal Coordination abnormal x
Sexual dysfunction Sexual dysfunction x x x x x x x x x
Throat irritation Burning in throat x x x x x
Gait disturbance Gait disturbance x
Prostate cancer Prostate carcinoma x
Breast cancer Carcinoma breast x
Lung neoplasm malignant Carcinoma of lung x
Tardive dyskinesia Tardive dyskinesia x x x x x
Skin cancer Skin carcinoma x
Electrocardiogram change Electrocardiogram change x x x
Oral discomfort Lip burning sensation of x x x x x x
Cardiomyopathy Cardiomyopathy x
Cerebral ischaemia Cerebral ischaemia x
Female sexual dysfunction Female sexual dysfunction x x x
Blood pressure fluctuation Change in blood pressure x x x
Benign prostatic hyperplasia Prostatic hypertrophy x x x x x
Ageusia Ageusia x
Visual impairment Abnormal vision x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

SELEGILINE

Side effects:43
Source:FDA Structured Product Label

Selegiline hydrochloride / Selgene

Side effects:93
Source:medicines.org.au

SELEGILINE

Side effects:42
Source:FDA Structured Product Label

SELEGILINE

Side effects:94
Source:FDA Structured Product Label

Selegiline

Side effects:100
Source:FDA Structured Product Label

SELEGILINE

Side effects:100
Source:FDA Structured Product Label

Selegiline

Side effects:100
Source:FDA Structured Product Label

SELEGILINE HYDROCHLORIDE / GEN-SELEGILINE 5MG

Side effects:112
Source:Health Canada

SELEGILINE

Side effects:175
Source:FDA Structured Product Label

SELEGILINE / EMSAM

Side effects:189
Source:FDA

SELEGILINE / EMSAM

Side effects:189
Source:FDA

SELEGILINE HYDROCHLORIDE / ZELAPAR

Side effects:196
Source:FDA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label