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More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: L01CB02

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3
Neutropenia Neutropenia 95% x
Leukopenia Leukopenia 89% x x
Anaemia Anaemia 88% x x
Thrombocytopenia Thrombocytopenia 85% x x
Mucosal inflammation Mucosal inflammation 76% x x
Pancytopenia Myelosuppression 75% x x x
Bone marrow depression x
Diarrhoea Diarrhoea 1% - 33% x x x
Nausea Nausea 29% x x x
Vomiting Vomiting 29% x x x
Infection Infection 12% x x
Alopecia Alopecia 9% x x x
Haemorrhage Haemorrhage 5% x
Haemoglobin Haemorrhage 5% x
Hypersensitivity Hypersensitivity 5% x x x
Dermatitis Rash 3% x
Rash Rash 3% x
Body temperature increased Body temperature increased 3% x x
Hypotension Hypotension 2% x x x
Hypotensive x
Nephropathy toxic Nephrotoxicity 2% x
Liver function test abnormal Raised liver function tests 2% x
Decreased appetite Anorexia 1% x x
Hepatic function abnormal Hepatic function abnormal 1% x x
Neurotoxicity Neurotoxicity 1% x x
Abdominal pain Abdominal pain x
Gastrointestinal pain Abdominal pain x
Haemolytic anaemia Haemolytic anaemia x
Arrhythmia Arrhythmia x x
Asthenia Asthenia x x
Bronchospasm Bronchospasm x x x
Chest pain Chest pain x
Confusional state Confusional state x x
Feeling abnormal Confusional state x x
Cyanosis Cyanosis x
Sudden death Sudden death x x
Dyspnoea Dyspnoea x x
Oedema Oedema x
Extravasation Extravasation x x
Flushing Flushing x x x
Headache Headache x x
Hypertension Hypertension x x
Leukaemia Leukaemia x
Acute myeloid leukaemia Acute myeloid leukaemia x x x
Acute leukaemia Acute myeloid leukaemia x x x
Pallor Pallor x
Neuropathy peripheral Neuropathy peripheral x
Neuropathy x x
Pruritus Pruritus x
Stomatitis Stomatitis x x
Hyperhidrosis Sweating x x
Tachycardia Tachycardia x x
Urticaria Urticaria x x
Chills Chills x x x
Agitation Agitation x
Metabolic acidosis Metabolic acidosis x
Sepsis Sepsis x
Neoplasm Solid tumour x
Haematological malignancy Haematological malignancy x
Electrocardiogram change Electrocardiogram change x
Cardiotoxicity Cardiotoxicity x
Gastrointestinal toxicity Gastrointestinal toxicity x
Phlebitis Chemical phlebitis x


Information about indications was extracted from the indications and usage sections of the labels.


Side effects:24
Source:BC Cancer


Side effects:39
Source:FDA Structured Product Label


Side effects:40
Source:Health Canada

Color scheme:


    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    no frequency information
    not found on label