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Tigecycline

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: J01AA12

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8
Diarrhoea very common, 10.8% - 12.7% x x x x x x x x
Local reaction 9% - 9.1% x x x x x x
Vomiting very common, 1% - 19.7% x x x x x x x x
Body temperature increased 7.1% - 9.8% x x x x x x
Nausea very common, 1% - 29.5% x x x x x x x x
Thrombocytosis 6.1% - 6.2% x x x x x x
Headache common, 5.9% - 7% x x x x x x x x
Abdominal pain common, 4% - 6.8% x x x x x x x x
Infection common, 5% - 8.3% x x x x
Hypertension 4.9% - 5.6% x x x x x x
Anorexia common x x x x x x x x
Angiopathy common x
Prothrombin level increased common x x x x x x x x
Alanine aminotransferase increased common, 4.7% - 5.6% x x x x x x
Activated partial thromboplastin time prolonged common x x x x x x x
Pseudomembranous colitis common x x
Anaemia 4.2% - 6% x x x x x x x
Hypoproteinaemia common, 3% - 5% x x x x x x x x
Aspartate aminotransferase increased common, 4% - 5% x x x x x x
Pruritus common, 2.6% - 4.1% x x x x x x x x
Rash common, 2.4% - 4.1% x x x x x x x
Phlebitis common, 1.8% - 4% x x x x x x x x
Lactic dehydrogenase activity increased 3.5% - 4% x x x x x x
Cough increased 3.7% - 3.8% x x x x x x
Constipation 2.8% - 4.1% x x x x x x
Pain 2.9% - 3.7% x x x x x x
Oedema peripheral 3.3% x x x x x x
Dizziness common, 2.7% - 3.5% x x x x x x x x
Abscess common, 2% - 3.2% x x x x x x x x
Leukocytosis 2.5% - 3.7% x x x x x x
Amylase increased common, 1.4% - 3.1% x x x x x x x x
Phosphatase alkaline increased 2.6% - 3.5% x x x x x x x
Dyspnoea 2.7% - 2.9% x x x x x x
Insomnia 2.3% - 3.3% x x x x x x
Impaired healing postmarketing — 2% - 3.5% x x x x x x x x
Hypokalaemia 2.1% - 2.9% x x x x x x
Dyspepsia common, 1.6% - 2.9% x x x x x x x x
Hyperglycaemia 1.8% - 2.9% x x x x x x
Asthenia 1.7% - 3% x x x x x x x
Hyperbilirubinaemia common, 0.9% - 2.3% x x x x x x x x
Blood urea increased common, 0.2% - 3% x x x x x x
Serum urea increased common, 0.2% - 2.1% x x
Hypotension 1.7% - 2.3% x x x x x x
Pneumonia postmarketing — 2% x x x x x
Sweating 1.6% - 2.3% x x x x x x
Back pain 1.2% - 2.3% x x x x x
Hyponatraemia 1% - 2% x x x x x
Septic shock uncommon, common x x x x x x x x
Thrombophlebitis uncommon x x x x x x x x
Injection site swelling uncommon x x x x x x x x
Injection site inflammation uncommon x x x x x x x x
Injection site reaction postmarketing — common x x x x x x x x
Injection site pain uncommon x x x x x x x x
Liver injury uncommon x
Sepsis uncommon, common x x x x x x x x
Injection site phlebitis uncommon x x x x x x x x
Thrombocytopenia postmarketing, uncommon x x x x x x x
Pancreatitis acute postmarketing, uncommon x x x x x x x
Anaphylactic shock postmarketing x x x x x
Cholestasis postmarketing x x x
Diabetes mellitus postmarketing x
Gastrointestinal disorder postmarketing x x x
Hypoglycaemia postmarketing, common x x x x x x x x
Immune system disorder postmarketing x x x
Jaundice postmarketing, uncommon x x x x x x x x
Mediastinal disorder postmarketing x x
Stevens-Johnson syndrome postmarketing x x x x
Malnutrition postmarketing x x x
Unspecified disorder of skin and subcutaneous tissue postmarketing x x x
Hepatobiliary disease postmarketing x x x
Anaphylactoid reaction postmarketing x x x x x
Blood and lymphatic system disorders postmarketing x x
Abdominal distension x
Acidosis x
Atrial fibrillation x
Coagulopathy x
Candida infection x
Oral candidiasis x
Vaginal moniliasis x x x x x
Cardiovascular disorder x x
Chest pain x
Confusional state x
Fungal skin infection x
Dysgeusia x x x x x
Ecchymosis x
Eosinophilia x x x x x
Faecal incontinence x
Flatulence x
Gastrooesophageal reflux disease x
Glossitis x
Cardiac failure congestive x
Herpes simplex x
Hiccups x
Hyperkalaemia x
Hypersensitivity x x x x x
Hypocalcaemia x x x x x
Leukopenia x
Leukorrhea x x x x x
Nervous system disorder x x x
Nervousness x
Neutropenia x
Osteomyelitis x x
Palpitations x
Pancreatitis x x
Peritonitis x
Pharyngitis x
Pleural effusion x
Polyuria x
Prurigo x
Benign intracranial hypertension x
Syncope x
Tachycardia x x x x
Sinus tachycardia x
Tooth discolouration x
Tremor x
Urinary tract infection x
Urticaria x
Vaginal inflammation x x x x x
Vertigo x
Vulvovaginitis x
Wound infection x x x x x x
Dry mouth x x x x
Chills x x x x x
Hepatic failure x x
Sinus bradycardia x
Ventricular arrhythmia x
Atrioventricular block first degree x
Hyperphosphataemia x x
Hypophosphataemia x
Creatine phosphokinase increased x
Creatinine renal clearance decreased x
Creatinine increased x x x x x
Scrotal oedema x
Ventricular extrasystoles x
Hypomagnesaemia x
Kidney function abnormal x
Hepatocellular injury x
Liver function test abnormal x
Electrocardiogram QT prolonged x
Skin discolouration x
Vulvovaginal disorder x
Abnormal faeces x x x x x
Malaise x
Myalgia x
Muscle twitching x
Sputum increased x
Azotaemia x
Mucosal inflammation x
Photosensitivity x
Rash maculo-papular x
Bradycardia x x x x
Electrocardiogram abnormal x
Prothrombin level decreased x
Prothrombin time shortened x
Diabetic foot infection x x
Infestation NOS x x x
International normalised ratio increased x
Nosocomial pneumonia x x x
Device malfunction x
Ventilator associated pneumonia x x
Somnolence x x x x
Abnormal vision x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

tigecycline / tigecycline

Side effects:56
Source:EMA

TIGECYCLINE

Side effects:53
Source:FDA Structured Product Label

TIGECYCLINE / TYGACIL

Side effects:67
Source:FDA

TIGECYCLINE / TYGACIL

Side effects:68
Source:FDA

TIGECYCLINE / TYGACIL

Side effects:69
Source:FDA

TIGECYCLINE / TYGACIL

Side effects:133
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label