Zidovudine
Side effects
Options:
Show MedDRA Preferred Terms,
display only 20 labels
|
Side effect
|
Data for drug
|
Placebo
|
Labels
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1
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2
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3
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4
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5
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6
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7
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8
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9
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10
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11
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12
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13
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14
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15
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16
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17
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18
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19
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20
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21
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22
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23
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24
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25
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26
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Headache
|
very common, 8.5% - 63%
|
37% - 53%
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Malaise
|
common, 8% - 55.6%
|
7% - 45%
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Nausea
|
rare — 7% - 61%
|
18% - 41%
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Body temperature increased
|
uncommon, 2.13% - 32%
|
12%
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Anorexia
|
rare, 6.38% - 20.1%
|
8% - 11%
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Gastrointestinal pain
|
20%
|
19%
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|
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x
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x
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x
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x
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x
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x
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Cough
|
rare, 15% - 18%
|
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Vomiting
|
common, 2.13% - 25%
|
3% - 13%
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Rash
|
postmarketing — 12% - 17%
|
15%
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Stomatitis
|
6% - 12%
|
|
|
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Hepatomegaly
|
postmarketing — 11%
|
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Rhinorrhoea
|
8% - 11%
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|
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Asthenia
|
uncommon, 8.6% - 9%
|
5.8% - 6%
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Wheezing
|
7% - 9%
|
|
|
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Breath sounds abnormal
|
7% - 9%
|
|
|
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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|
|
|
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Lymphadenopathy
|
postmarketing, 9% - 11%
|
|
|
|
x
|
x
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Splenomegaly
|
5% - 8%
|
|
|
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Myalgia
|
common, 8%
|
2%
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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|
Abdominal pain
|
common, 8.51% - 21.3%
|
|
x
|
x
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Constipation
|
6% - 8.1%
|
3.5% - 4%
|
|
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Diarrhoea
|
common, 6% - 14.9%
|
18%
|
x
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Weight decreased
|
4.26% - 6.38%
|
|
|
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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Rigors
|
2.13% - 8.51%
|
|
|
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|
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|
|
|
|
|
|
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x
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x
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x
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Dyspepsia
|
rare, 5% - 6%
|
1% - 4%
|
x
|
x
|
x
|
x
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
|
x
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x
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x
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x
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x
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x
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x
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x
|
|
Sweating increased
|
5%
|
4%
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
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|
|
|
x
|
x
|
x
|
x
|
x
|
x
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|
Hyperlactacidaemia
|
common
|
|
x
|
x
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|
|
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|
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|
|
|
|
|
|
|
|
|
x
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x
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Insomnia
|
rare, 5%
|
1%
|
x
|
x
|
x
|
x
|
x
|
x
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x
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x
|
x
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x
|
x
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x
|
x
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x
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x
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x
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x
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x
|
x
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x
|
x
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x
|
x
|
x
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x
|
x
|
|
Neuropathy peripheral
|
4% - 25.5%
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
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|
|
x
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x
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x
|
|
Neutropenia
|
common, 3%
|
|
x
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
|
x
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x
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x
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x
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x
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x
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x
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x
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Pharyngitis
|
2.1% - 8.51%
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
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|
Agranulocytosis
|
1.8% - 2%
|
1.6% - 2%
|
|
|
x
|
x
|
x
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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|
x
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x
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x
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Anaemia
|
common, 1% - 2%
|
0.2% - 1%
|
x
|
x
|
x
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
|
x
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x
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x
|
x
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x
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x
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Pain
|
uncommon
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
|
|
|
|
Thrombocytopenia
|
uncommon, 0% - 3%
|
0.5% - 1%
|
x
|
x
|
x
|
x
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Lactic acidosis
|
postmarketing, rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Amblyopia
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
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x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Anaphylactic shock
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
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x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Aplastic anaemia
|
very rare, postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
|
Haemolytic anaemia
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Angioedema
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
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Anxiety
|
postmarketing, rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
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x
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x
|
x
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x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Back pain
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
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x
|
x
|
x
|
x
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x
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x
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x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Chest pain
|
postmarketing — 2.13% - 6.38%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
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x
|
x
|
x
|
x
|
|
Confusional state
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dysphagia
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dizziness
|
postmarketing — 6% - 20.8%
|
4% - 15.2%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dysgeusia
|
postmarketing — 5%
|
8%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dyspnoea
|
postmarketing — 5%
|
3%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Toxic epidermal necrolysis
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Flatulence
|
postmarketing, uncommon
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Gynaecomastia
|
postmarketing, rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
|
|
x
|
x
|
x
|
|
Hepatitis
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Influenza
|
rare
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Jaundice
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Leukopenia
|
postmarketing, common
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
|
Liver disorder
|
rare
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
Myopathy
|
postmarketing, uncommon
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Myositis
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Pancreatitis
|
postmarketing
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pancytopenia
|
postmarketing, uncommon
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
|
Paraesthesia
|
postmarketing — 6%
|
3%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pruritus
|
postmarketing, uncommon
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Aplasia pure red cell
|
postmarketing, rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
|
|
|
x
|
x
|
x
|
|
Rhabdomyolysis
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Rhinitis
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Convulsion
|
postmarketing, rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Sinusitis
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pigmentation skin
|
rare
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Muscle spasms
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Stevens-Johnson syndrome
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Sweating
|
rare
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
Syncope
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Tremor
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pollakiuria
|
postmarketing, rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Urticaria
|
postmarketing, rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Vasculitis
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Vertigo
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Chills
|
rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Photophobia
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Mouth ulceration
|
postmarketing, 4.26% - 27.7%
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Lactic dehydrogenase activity increased
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Bone marrow depression
|
postmarketing, uncommon
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
|
Urinary hesitation
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Macular oedema
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Generalized aching
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Mania
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Cardiomyopathy
|
postmarketing, rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Nail pigmentation
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Sensitisation
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hearing impaired
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Mucosal pigmentation
|
postmarketing, rare
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
|
Somnolence
|
postmarketing — 8%
|
9%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Abdominal cramps
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Congenital anomaly
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
Acidosis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
Acquired immunodeficiency syndrome
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
Arthralgia
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Bacteraemia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Mental disorder
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Breast disorder
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Connective tissue disorder
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Cystitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Dysuria
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Oedema
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Epistaxis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Eructation
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Fatigue
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
|
Gastrointestinal disorder
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Gingival bleeding
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Cardiac disorder
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Cardiac failure congestive
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Haematuria
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Hepatitis C
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
x
|
|
|
|
|
|
|
|
Hoarseness
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hyperpathia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hyperbilirubinaemia
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Irritability
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Mediastinal disorder
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Musculoskeletal pain
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Nervous system disorder
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Nervousness
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Night sweats
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Phlebitis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Polyuria
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Erythema
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Urinary tract disorder
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Vasodilation
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Body odor
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Mood swings
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Generalised oedema
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
Tongue oedema
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
|
Hyporeflexia
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
Aspartate aminotransferase increased
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
Skin discolouration
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
Malnutrition
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
Unspecified disorder of skin and subcutaneous tissue
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Sickness
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Muscle twitching
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Rash erythematous
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Rash follicular
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Swollen tongue
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
x
|
x
|
|
Oedema auricular
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Rectal haemorrhage
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Hepatobiliary disease
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Red cell aplasia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
Rash maculo-papular
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
|
Neuropathy
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Auricular swelling
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
Drug interaction
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
Hypoxemia
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
Acne
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
|
x
|
|
Blood and lymphatic system disorders
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Local reaction
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
x
|
|
|
|
|
Fat redistribution
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
| Side effects: | 59 |
|---|
| Source: | Medsafe |
|---|
| Side effects: | 61 |
|---|
| Source: | Medsafe |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA |
|---|
| Side effects: | 97 |
|---|
| Source: | FDA |
|---|
| Side effects: | 98 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 97 |
|---|
| Source: | FDA |
|---|
| Side effects: | 98 |
|---|
| Source: | FDA Structured Product Label |
|---|
| Side effects: | 95 |
|---|
| Source: | medicines.org.au |
|---|
| Side effects: | 93 |
|---|
| Source: | FDA |
|---|
| Side effects: | 94 |
|---|
| Source: | FDA |
|---|
| Side effects: | 108 |
|---|
| Source: | Health Canada |
|---|
| Side effects: | 107 |
|---|
| Source: | Health Canada |
|---|
| Side effects: | 108 |
|---|
| Source: | Health Canada |
|---|
Color scheme:
standard – alternative
|
|
|
100%
|
|
|
|
75%
|
|
|
|
50%
|
|
|
|
10%
|
|
|
|
frequent (1% to 100%)
|
|
|
|
infrequent (0.1% to 1%)
|
|
|
|
rare (<0.1%)
|
|
|
|
postmarketing
|
|
|
|
0%
|
|
|
|
no frequency information
|
|
|
|
not found on label
|
