Adapalene

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9
Dry skin def 3% - 26.9% 1.49% - 3% x x x x x
Skin exfoliation 0.1% - 25.3% 0% x x x x x x x x x
Stinging 0.4% - 22.1% x x x x x x x x x
Erythema def 0.2% - 21.8% x x x x x x x x x
Discomfort def 0% - 11.2% 0% x x x x x x x
Angioedema def postmarketing x x
Oedema def postmarketing x x x x x
Pain def postmarketing x x x
Swelling def postmarketing x x
Skin irritation def postmarketing x x x x x x x x x
Eyelid oedema postmarketing x x x x x
Lip swelling postmarketing x x
Lymphoid interstitial pneumonia def postmarketing x x
Face oedema def postmarketing x x x
Conjunctivitis def x x x x
Convulsion def x
Dermatitis def x x x x x
Dermatitis atopic def x
Dermatitis contact def x x x x x
Eczema def x x x x x
Rash def x x x x x
Foetal disorder def x
Hepatitis def x
Herpes NOS def x
Herpes simplex def x
Keratoconjunctivitis def x
Papilloedema def x
Pruritus def x x x x x x x
Seborrhoeic dermatitis def x
Urticaria def x
Eye pain def x
Skin discolouration def x x x x x
Dermatitis irritant contact def x
Rash vesicular x
Atopy def x
Skin oedema x
Indication Labels
Acne def x x x x x x x x
Acne vulgaris def x x x x x x x
Elderly def x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: D10AD03

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. ADAPALENE : 5 side effects (FDA XML label)
  2. Adapalene : 5 side effects (FDA XML label)
  3. ADAPALENE : 6 side effects (FDA XML label)
  4. Adapalene : 6 side effects (FDA XML label)
  5. adapalene : 14 side effects (FDA XML label)
  6. ADAPALENE / DIFFERIN : 14 side effects (Drugs@FDA)
  7. ADAPALENE : 21 side effects (FDA XML label)
  8. ADAPALENE : 21 side effects (FDA XML label)
  9. ADAPALENE / DIFFERIN : 31 side effects (Health Canada)