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Adapalene

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: D10AD03

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10
Burning sensation Burning sensation very common x
Erythema Redness very common x
Erythema 0% - 26.1% x x x x x x x x x x
Dry skin Dry skin very common, 0.322% - 14% x x x x x x x
Pain Stinging 1% - 28.5% x x x x x x x x x x
Pain x
Skin discomfort Skin discomfort 0% - 6.44% x x x x x x x x
Sunburn Sunburn 0.6% - 2% x x x x x x x x x
Photosensitivity reaction Sunburn 0.6% - 2% x x x x x x x x x
Phototoxicity x
Dermatitis contact Dermatitis irritant contact 0% - 5.43% x
Dermatitis contact uncommon x x x x x x x
Pruritus Pruritus 0% - 1.9% x x x x x x x x x
Skin exfoliation Skin exfoliation 0% - 2.58% x x x x x x
Dermatitis exfoliative Dermatitis exfoliative uncommon x
Excoriation Abrasion NOS uncommon x
Skin irritation Skin irritation postmarketing, 0% - 1.61% x x x x x x x
Angioedema Angioedema postmarketing x x x
Hypersensitivity Hypersensitivity rare x
Drug ineffective Lack of drug effect rare x
Eyelid oedema Eyelid oedema postmarketing x x x x x x x
Swelling of eyelid x
Lip swelling Lip swelling postmarketing x x x
Application site pain Application site pain postmarketing x x x
Instillation site pain Application site pain postmarketing x x x
Face oedema Face oedema postmarketing x x x x
Conjunctivitis Conjunctivitis x x x x x
Dermatitis Dermatitis x x
Rash x x x x x
Dermatitis atopic Dermatitis atopic x
Eczema Eczema x x x x x x x
Rash Rash x x x x x
Foetal disorder Foetal disorder x
Hepatitis Hepatitis x
Oral herpes Herpes labialis x
Herpes simplex Herpes simplex x
Keratitis Keratoconjunctivitis x
Optic neuritis Papilloedema x
Papilloedema Papilloedema x
Seborrhoeic dermatitis Seborrhoeic dermatitis x
Convulsion Convulsion x
Urticaria Urticaria x
Eye pain Eye pain x
Rash pustular Vesiculobullous rash x
Dermatitis bullous Vesiculobullous rash x
Skin discolouration Skin discolouration x x x x x x
Rash vesicular Rash vesicular x
Erythema of eyelid Erythema of eyelid x
Pain of skin Pain of skin x
Skin swelling Skin swelling x
Skin oedema Skin oedema x
Feeling hot Sensation of warmth x
Eyelids pruritus Eyelids pruritus x
Eyelid irritation Eyelid irritation x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

DIFFERIN topical gel / Differin, Topical gel

Side effects:26
Source:Medsafe

Adapalene

Side effects:3
Source:FDA Structured Product Label

ADAPALENE

Side effects:5
Source:FDA Structured Product Label

Adapalene

Side effects:6
Source:FDA Structured Product Label

ADAPALENE / DIFFERIN

Side effects:13
Source:FDA

ADAPALENE / DIFFERIN

Side effects:13
Source:FDA

ADAPALENE

Side effects:18
Source:FDA Structured Product Label

ADAPALENE

Side effects:18
Source:FDA Structured Product Label

ADAPALENE

Side effects:18
Source:FDA Structured Product Label

ADAPALENE / DIFFERIN

Side effects:28
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label