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Acute promyelocytic leukaemia

Definition: An acute myeloid leukemia (AML) in which abnormal promyelocytes predominate. It is characterized by the t(15;17)(q22;q12) translocation. There are two variants: the typical and microgranular variant. This AML is particularly sensitive to treatment with all trans-retinoic acid and has a favorable prognosis. (WHO, 2001)

Synonyms (terms occurring on more labels are shown first): acute promyelocytic leukemia, acute promyelocytic leukaemia, AML-M3

More information: PubMed search and possibly Wikipedia

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