Rasagiline
Side effects
Options:
Show MedDRA Preferred Terms
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
|
3
|
4
|
5
|
Dyskinesia
|
18%
|
10%
|
x
|
x
|
x
|
x
|
x
|
Headache
|
6% - 14%
|
4% - 12%
|
x
|
x
|
x
|
x
|
x
|
Accidental injury
|
8% - 12%
|
5%
|
x
|
|
x
|
x
|
x
|
Nausea
|
common, 6% - 12%
|
4% - 8%
|
x
|
x
|
x
|
x
|
x
|
Arthralgia
|
common, 5% - 8%
|
2% - 4%
|
x
|
x
|
x
|
x
|
x
|
Dizziness
|
7%
|
6%
|
x
|
|
x
|
x
|
x
|
Dyspepsia
|
4% - 7%
|
4%
|
x
|
|
x
|
x
|
x
|
Oedema peripheral
|
7%
|
4%
|
x
|
|
|
|
|
Diarrhoea
|
5% - 7%
|
4%
|
x
|
|
x
|
x
|
x
|
Orthostatic hypotension
|
common, 3% - 9%
|
1% - 3%
|
x
|
x
|
x
|
x
|
x
|
Abdominal pain
|
common, 2% - 5%
|
1%
|
x
|
x
|
x
|
x
|
x
|
Anxiety
|
frequent
|
|
|
|
x
|
x
|
x
|
Asthenia
|
frequent
|
|
|
|
x
|
x
|
x
|
Bundle branch block
|
frequent
|
|
|
|
x
|
x
|
x
|
Carpal tunnel syndrome
|
common
|
|
|
x
|
|
|
|
Constipation
|
common, 4% - 9%
|
5%
|
x
|
x
|
x
|
x
|
x
|
Depression
|
5%
|
2%
|
x
|
|
x
|
x
|
x
|
Dermatitis
|
common
|
|
|
x
|
|
|
|
Rash
|
common, 3% - 6%
|
3%
|
x
|
x
|
x
|
x
|
x
|
Gastrointestinal haemorrhage
|
frequent
|
|
|
|
x
|
x
|
x
|
Hallucination
|
common, 4% - 5%
|
3%
|
x
|
x
|
x
|
x
|
x
|
Haematuria
|
frequent
|
|
|
|
x
|
x
|
x
|
Hypersensitivity
|
common
|
|
|
x
|
x
|
x
|
x
|
Influenza
|
common, 5%
|
1%
|
x
|
x
|
x
|
x
|
x
|
Leukopenia
|
common
|
|
|
x
|
x
|
x
|
x
|
Hypertonia
|
frequent
|
|
|
|
x
|
x
|
x
|
Musculoskeletal pain
|
common
|
|
|
x
|
|
|
|
Tremor
|
frequent
|
|
|
|
x
|
x
|
x
|
Urinary incontinence
|
frequent
|
|
|
|
x
|
x
|
x
|
Vomiting
|
common, 4% - 7%
|
1%
|
x
|
x
|
x
|
x
|
x
|
Weight decreased
|
common, 2% - 9%
|
3%
|
x
|
x
|
x
|
x
|
x
|
Dry mouth
|
common, 2% - 6%
|
3%
|
x
|
x
|
x
|
x
|
x
|
Micturition urgency
|
common
|
|
|
x
|
|
|
|
Hyperkinesia
|
frequent
|
|
|
|
x
|
x
|
x
|
Neuropathy
|
frequent
|
|
|
|
x
|
x
|
x
|
Cough increased
|
frequent
|
|
|
|
x
|
x
|
x
|
Gait disturbance
|
frequent
|
|
|
|
x
|
x
|
x
|
Balance disorder
|
common
|
|
|
x
|
|
|
|
Skin carcinoma
|
common
|
|
|
x
|
x
|
x
|
x
|
Somnolence
|
4% - 6%
|
4%
|
x
|
|
x
|
x
|
x
|
Ataxia
|
3% - 6%
|
1%
|
x
|
|
x
|
x
|
x
|
Back pain
|
4%
|
3%
|
x
|
|
|
|
|
Cough
|
4%
|
1%
|
x
|
|
|
|
|
Dyspnoea
|
3% - 5%
|
2%
|
x
|
|
x
|
x
|
x
|
Upper respiratory tract infection
|
4%
|
2%
|
x
|
|
|
|
|
Abnormal dreams
|
common, 1% - 4%
|
1%
|
x
|
x
|
x
|
x
|
x
|
Insomnia
|
4%
|
1%
|
x
|
|
|
|
|
Anorexia
|
2% - 5%
|
1%
|
x
|
|
x
|
x
|
x
|
Conjunctivitis
|
common, 3%
|
1%
|
x
|
x
|
x
|
x
|
x
|
Body temperature increased
|
common, 3%
|
1%
|
x
|
x
|
x
|
x
|
x
|
Gastroenteritis
|
3%
|
1%
|
x
|
|
x
|
x
|
x
|
Rhinitis
|
common, 3%
|
1%
|
x
|
x
|
x
|
x
|
x
|
Angina pectoris
|
uncommon, common
|
|
|
x
|
x
|
x
|
x
|
Decreased appetite
|
uncommon, common
|
|
|
x
|
|
|
|
Infection
|
2% - 3%
|
2%
|
x
|
x
|
x
|
x
|
x
|
Sweating
|
2% - 3%
|
1%
|
x
|
|
x
|
x
|
x
|
Arthritis
|
common, 2%
|
1%
|
x
|
x
|
x
|
x
|
x
|
Neck pain
|
common, 1% - 3%
|
0% - 1%
|
x
|
x
|
x
|
x
|
x
|
Ecchymosis
|
2% - 5%
|
0% - 3%
|
x
|
|
x
|
x
|
x
|
Paraesthesia
|
2% - 5%
|
1% - 3%
|
x
|
|
x
|
x
|
x
|
Tenosynovitis
|
1% - 3%
|
0%
|
x
|
|
x
|
x
|
x
|
Vertigo
|
common, 2%
|
1%
|
x
|
x
|
x
|
x
|
x
|
Malaise
|
common, 2%
|
0%
|
x
|
x
|
x
|
x
|
x
|
Myasthenia
|
2%
|
1%
|
x
|
|
x
|
x
|
x
|
Gingivitis
|
1% - 2%
|
1%
|
x
|
|
x
|
x
|
x
|
Haemorrhage
|
1% - 2%
|
1%
|
x
|
|
x
|
x
|
x
|
Hernia
|
1% - 2%
|
1%
|
x
|
|
x
|
x
|
x
|
Anaemia macrocytic
|
infrequent
|
|
|
|
|
x
|
x
|
Aphasia
|
infrequent
|
|
|
|
x
|
x
|
x
|
Apnoea
|
infrequent
|
|
|
|
x
|
x
|
x
|
Blepharitis
|
infrequent
|
|
|
|
x
|
x
|
x
|
Vaginal moniliasis
|
infrequent
|
|
|
|
x
|
x
|
x
|
Colitis
|
infrequent
|
|
|
|
x
|
x
|
x
|
Confusional state
|
uncommon
|
|
x
|
x
|
|
x
|
x
|
Deafness
|
infrequent
|
|
|
|
x
|
x
|
x
|
Delusion
|
infrequent
|
|
|
|
x
|
x
|
x
|
Diplopia
|
infrequent
|
|
|
|
x
|
x
|
x
|
Dysarthria
|
infrequent
|
|
|
|
x
|
x
|
x
|
Dysautonomia
|
infrequent
|
|
|
|
x
|
x
|
x
|
Dysgeusia
|
infrequent
|
|
|
|
x
|
x
|
x
|
Dysmenorrhoea
|
infrequent
|
|
|
|
x
|
x
|
x
|
Dysuria
|
infrequent
|
|
|
|
x
|
x
|
x
|
Eczema
|
infrequent
|
|
|
|
x
|
x
|
x
|
Oesophagitis
|
infrequent
|
|
|
|
x
|
x
|
x
|
Eye haemorrhage
|
infrequent
|
|
|
|
x
|
x
|
x
|
Facial paralysis
|
infrequent
|
|
|
|
x
|
x
|
x
|
Faecal incontinence
|
infrequent
|
|
|
|
x
|
x
|
x
|
Flank pain
|
infrequent
|
|
|
|
x
|
x
|
x
|
Glaucoma
|
infrequent
|
|
|
|
x
|
x
|
x
|
Cardiac failure
|
infrequent
|
|
|
|
x
|
x
|
x
|
Hemiplegia
|
infrequent
|
|
|
|
x
|
x
|
x
|
Hypoaesthesia
|
infrequent
|
|
|
|
x
|
x
|
x
|
Hypocalcaemia
|
infrequent
|
|
|
|
x
|
x
|
x
|
Intestinal obstruction
|
infrequent
|
|
|
|
x
|
x
|
x
|
Keratitis
|
infrequent
|
|
|
|
x
|
x
|
x
|
Calculus of kidney
|
infrequent
|
|
|
|
x
|
x
|
x
|
Renal failure acute
|
infrequent
|
|
|
|
x
|
x
|
x
|
Laryngospasm
|
infrequent
|
|
|
|
x
|
x
|
x
|
Muscle atrophy
|
infrequent
|
|
|
|
x
|
x
|
x
|
Myocardial infarction
|
infrequent, uncommon
|
|
|
x
|
x
|
x
|
x
|
Myoclonus
|
infrequent
|
|
|
x
|
x
|
x
|
x
|
Neuritis
|
infrequent
|
|
|
|
x
|
x
|
x
|
Neurosis
|
infrequent
|
|
|
|
x
|
x
|
x
|
Nocturia
|
infrequent
|
|
|
|
x
|
x
|
x
|
Osteonecrosis
|
infrequent
|
|
|
|
x
|
x
|
x
|
Personality disorder
|
infrequent
|
|
|
|
x
|
x
|
x
|
Phlebitis
|
infrequent
|
|
|
|
x
|
x
|
x
|
Pleural effusion
|
infrequent
|
|
|
|
x
|
x
|
x
|
Pneumothorax
|
infrequent
|
|
|
|
x
|
x
|
x
|
Polyuria
|
infrequent
|
|
|
|
x
|
x
|
x
|
Psychotic disorder
|
infrequent
|
|
x
|
|
x
|
x
|
x
|
Emphysema
|
infrequent
|
|
|
|
x
|
x
|
x
|
Retinal degeneration
|
infrequent
|
|
|
|
x
|
x
|
x
|
Scotoma
|
infrequent
|
|
|
|
x
|
x
|
x
|
Convulsion
|
infrequent
|
|
|
|
x
|
x
|
x
|
Gastric ulcer
|
infrequent
|
|
|
|
x
|
x
|
x
|
Stomatitis
|
infrequent
|
|
|
|
x
|
x
|
x
|
Cerebrovascular accident
|
uncommon
|
|
|
x
|
|
x
|
x
|
Thrombophlebitis
|
infrequent
|
|
|
|
x
|
x
|
x
|
Urticaria
|
infrequent
|
|
|
|
x
|
x
|
x
|
Vaginal inflammation
|
infrequent
|
|
|
|
x
|
x
|
x
|
Ventricular tachycardia
|
infrequent
|
|
|
|
x
|
x
|
x
|
Urinary retention
|
infrequent
|
|
|
|
x
|
x
|
x
|
Chills
|
infrequent
|
|
|
|
x
|
x
|
x
|
Agitation
|
infrequent
|
|
|
x
|
x
|
x
|
x
|
Mood swings
|
infrequent
|
|
|
|
x
|
x
|
x
|
Footdrop
|
infrequent
|
|
|
|
x
|
x
|
x
|
Mouth ulceration
|
infrequent
|
|
|
|
x
|
x
|
x
|
Migraine
|
infrequent
|
|
|
|
x
|
x
|
x
|
Scrotal oedema
|
infrequent
|
|
|
|
x
|
x
|
x
|
Tongue oedema
|
infrequent
|
|
|
|
x
|
x
|
x
|
Manic psychosis
|
infrequent
|
|
|
|
x
|
x
|
x
|
Melanoma skin
|
uncommon
|
|
|
x
|
|
|
|
Eye pain
|
infrequent
|
|
|
|
x
|
x
|
x
|
Paranoid reaction
|
infrequent
|
|
|
|
x
|
x
|
x
|
Circumoral paresthesia
|
infrequent
|
|
|
|
x
|
x
|
x
|
Vesiculobullous rash
|
uncommon
|
|
|
x
|
x
|
x
|
x
|
Oesophageal ulcer
|
infrequent
|
|
|
|
x
|
x
|
x
|
Photosensitivity reaction
|
infrequent
|
|
|
|
x
|
x
|
x
|
Urination impaired
|
infrequent
|
|
|
|
x
|
x
|
x
|
Wrist drop
|
infrequent
|
|
|
|
x
|
x
|
x
|
Dysaesthesia
|
infrequent
|
|
|
|
x
|
x
|
x
|
Dementia
|
infrequent
|
|
|
|
x
|
x
|
x
|
Coordination abnormal
|
infrequent
|
|
|
|
x
|
x
|
x
|
Face oedema
|
infrequent
|
|
|
|
x
|
x
|
x
|
Sexual dysfunction
|
infrequent
|
|
|
|
x
|
x
|
x
|
Vaginal haemorrhage
|
infrequent
|
|
|
|
x
|
x
|
x
|
Amenorrhoea
|
rare
|
|
|
|
x
|
x
|
x
|
Anuria
|
rare
|
|
|
|
x
|
x
|
x
|
Bipolar disorder
|
rare
|
|
|
|
x
|
x
|
x
|
Delirium
|
rare
|
|
|
|
x
|
x
|
x
|
Dermatitis exfoliative
|
rare
|
|
|
|
x
|
x
|
x
|
Epididymitis
|
rare
|
|
|
|
x
|
x
|
x
|
Gynaecomastia
|
rare
|
|
|
|
x
|
x
|
x
|
Haematemesis
|
rare
|
|
|
|
x
|
x
|
x
|
Hostility
|
rare
|
|
|
|
x
|
x
|
x
|
Libido increased
|
postmarketing
|
|
|
x
|
|
|
x
|
Intestinal perforation
|
rare
|
|
|
|
x
|
x
|
x
|
Jaundice
|
rare
|
|
|
|
x
|
x
|
x
|
Arthropathy
|
rare
|
|
|
|
x
|
x
|
x
|
Laryngeal oedema
|
rare
|
|
|
|
x
|
x
|
x
|
Leukorrhea
|
rare
|
|
|
|
x
|
x
|
x
|
Megacolon
|
rare
|
|
|
|
x
|
x
|
x
|
Melaena
|
rare
|
|
|
|
x
|
x
|
x
|
Myelitis
|
rare
|
|
|
|
x
|
x
|
x
|
Neuralgia
|
rare
|
|
|
|
x
|
x
|
x
|
Pathological gambling
|
postmarketing
|
|
|
x
|
|
|
x
|
Priapism
|
rare
|
|
|
|
|
x
|
x
|
Pulmonary fibrosis
|
rare
|
|
|
|
x
|
x
|
x
|
Purpura
|
rare
|
|
|
|
|
x
|
x
|
Retinal detachment
|
rare
|
|
|
|
x
|
x
|
x
|
Retinal haemorrhage
|
rare
|
|
|
|
x
|
x
|
x
|
Ventricular fibrillation
|
rare
|
|
|
|
x
|
x
|
x
|
Vestibular disorder
|
rare
|
|
|
|
x
|
x
|
x
|
Atrial arrhythmia
|
rare
|
|
|
|
x
|
x
|
x
|
Stupor
|
rare
|
|
|
|
x
|
x
|
x
|
Apathy
|
rare
|
|
|
|
x
|
x
|
x
|
Photophobia
|
rare
|
|
|
|
x
|
x
|
x
|
Atrioventricular block complete
|
rare
|
|
|
|
x
|
x
|
x
|
Large intestine perforation
|
rare
|
|
|
|
x
|
x
|
x
|
Arterial thrombosis
|
rare
|
|
|
|
x
|
x
|
x
|
Leukoderma
|
rare
|
|
|
|
x
|
x
|
x
|
Interstitial pneumonia
|
rare
|
|
|
|
x
|
x
|
x
|
Ventricular bigeminy
|
rare
|
|
|
|
x
|
x
|
x
|
Atrioventricular block second degree
|
rare
|
|
|
|
x
|
x
|
x
|
Intestinal stenosis
|
rare
|
|
|
|
x
|
x
|
x
|
Psychotic depression
|
rare
|
|
|
|
x
|
x
|
x
|
Hypersexuality
|
postmarketing
|
|
|
x
|
|
|
x
|
Blindness
|
rare
|
|
|
|
x
|
x
|
x
|
Hydroureter
|
rare
|
|
|
|
x
|
x
|
x
|
Thrombocytosis
|
rare
|
|
|
|
|
x
|
x
|
Cerebral ischaemia
|
rare
|
|
|
|
x
|
x
|
x
|
Parosmia
|
rare
|
|
|
|
x
|
x
|
x
|
Gastritis haemorrhagic
|
rare
|
|
|
|
x
|
x
|
x
|
Ageusia
|
rare
|
|
|
|
x
|
x
|
x
|
Abnormal ejaculation
|
rare
|
|
|
|
x
|
x
|
x
|
Cerebral haemorrhage
|
rare
|
|
|
|
x
|
x
|
x
|
Albuminuria
|
|
|
|
|
x
|
x
|
x
|
Alopecia
|
|
|
|
|
x
|
x
|
x
|
Amnesia
|
|
|
|
|
|
x
|
x
|
Anaemia
|
|
|
|
|
|
x
|
x
|
Asthma
|
|
|
|
|
x
|
x
|
x
|
Mental disorder
|
|
|
|
x
|
|
|
|
Bursitis
|
|
|
|
|
|
x
|
x
|
Chest pain
|
|
|
|
|
x
|
x
|
x
|
Connective tissue disorder
|
|
|
|
x
|
|
|
|
Cyst
|
|
|
|
x
|
|
|
|
Libido decreased
|
|
|
|
|
x
|
x
|
x
|
Dysphagia
|
|
|
|
|
|
x
|
x
|
Epistaxis
|
|
|
|
|
|
x
|
x
|
Eye disorder
|
|
|
|
x
|
|
|
|
Flatulence
|
|
|
|
x
|
|
|
|
Gastrointestinal disorder
|
|
|
|
x
|
|
|
|
Cardiac disorder
|
|
|
|
x
|
|
|
|
Hypertension
|
|
|
x
|
|
|
|
|
Hypertensive crisis
|
|
|
|
x
|
|
|
|
Hypotension
|
|
|
x
|
|
|
|
|
Immune system disorder
|
|
|
|
x
|
|
|
|
Impulse-control disorder
|
|
|
|
x
|
|
|
|
Cramps of lower extremities
|
|
|
|
|
|
x
|
x
|
Mediastinal disorder
|
|
|
|
x
|
|
|
|
Malignant melanoma
|
|
|
x
|
|
|
|
|
Muscle rigidity
|
|
|
|
x
|
|
|
|
Neoplasm
|
|
|
|
x
|
|
|
|
Nervous system disorder
|
|
|
|
x
|
|
|
|
Polyp
|
|
|
|
x
|
|
|
|
Pruritus
|
|
|
|
|
|
x
|
x
|
Skin ulcer
|
|
|
|
|
|
x
|
x
|
Syncope
|
|
|
|
|
x
|
x
|
x
|
Urinary tract disorder
|
|
|
|
x
|
|
|
|
Angiopathy
|
|
|
|
x
|
|
|
|
Fall
|
|
|
x
|
|
|
|
|
Liver function test abnormal
|
|
|
|
|
x
|
x
|
x
|
Malnutrition
|
|
|
|
x
|
x
|
x
|
x
|
Unspecified disorder of skin and subcutaneous tissue
|
|
|
|
x
|
|
|
|
Erectile dysfunction
|
|
|
|
|
x
|
x
|
x
|
Hyperpyrexia
|
|
|
x
|
|
|
|
|
Blood pressure increased
|
|
|
|
x
|
|
|
|
Binge eating
|
|
|
|
x
|
|
|
|
Compulsions
|
|
|
x
|
x
|
|
|
|
Obsessive thoughts
|
|
|
|
x
|
|
|
|
Drug interaction
|
|
|
|
x
|
|
|
|
Serotonin syndrome
|
|
|
x
|
x
|
|
|
|
Infestation NOS
|
|
|
|
x
|
|
|
|
Blood and lymphatic system disorders
|
|
|
|
x
|
|
|
|
Ear and labyrinth disorders
|
|
|
|
x
|
|
|
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 54 |
Source: | FDA Structured Product Label |
---|
Side effects: | 70 |
Source: | EMA |
---|
Side effects: | 185 |
Source: | Health Canada |
---|
Side effects: | 199 |
Source: | FDA |
---|
Side effects: | 202 |
Source: | FDA Structured Product Label |
---|
Color scheme:
standard – alternative
|
|
100%
|
|
|
75%
|
|
|
50%
|
|
|
10%
|
|
|
frequent (1% to 100%)
|
|
|
infrequent (0.1% to 1%)
|
|
|
rare (<0.1%)
|
|
|
postmarketing
|
|
|
0%
|
|
|
no frequency information
|
|
|
not found on label
|