MedDRA Preferred Term
|
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
Back pain
|
Back pain
|
postmarketing, 2.8% - 43.9%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Pain
|
Pain
|
2.4% - 16.6%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Pelvic pain
|
Pelvic pain
|
6.02% - 7.86%
|
|
x
|
x
|
x
|
x
|
x
|
|
|
Insomnia
|
Insomnia
|
1.4% - 6.57%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Anxiety
|
Anxiety
|
5.88% - 6.51%
|
|
x
|
x
|
x
|
x
|
x
|
|
|
Bradycardia
|
Bradycardia
|
postmarketing, 1.2% - 7.62%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hypertension
|
Hypertension
|
1% - 6.25%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Dyspepsia
|
Dyspepsia
|
4.63% - 5.16%
|
|
x
|
x
|
x
|
x
|
x
|
|
|
Abdominal pain
|
Abdominal pain
|
0.8% - 4.83%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Gastrointestinal pain
|
Abdominal pain
|
0.8% - 4.83%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Nervousness
|
Nervousness
|
4.04% - 4.72%
|
|
x
|
x
|
x
|
x
|
x
|
|
|
Tension
|
Nervousness
|
4.04% - 4.72%
|
|
x
|
x
|
x
|
x
|
x
|
|
|
Urinary retention
|
Urinary retention
|
4.12% - 4.56%
|
|
x
|
x
|
x
|
x
|
x
|
|
|
Ecchymosis
|
Ecchymosis
|
postmarketing, 0.0001% - 6%
|
|
|
|
|
|
|
x
|
x
|
Haemorrhage
|
Major bleed
|
postmarketing, 0.001% - 9.25%
|
|
|
x
|
x
|
|
|
|
x
|
Haemorrhage
|
postmarketing, 0.0001% - 28%
|
|
|
x
|
x
|
|
|
x
|
x
|
Hemorrhage symptom
|
|
|
|
|
|
|
x
|
|
|
Hypotension
|
Hypotension
|
postmarketing, 0.2% - 17.2%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Haemoglobin
|
Haemorrhage
|
postmarketing, 0.0001% - 28%
|
|
|
x
|
x
|
|
|
x
|
x
|
Headache
|
Headache
|
postmarketing, 0.2% - 12.2%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Body temperature increased
|
Body temperature increased
|
0.5% - 5.02%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Nausea
|
Nausea
|
postmarketing, 0.1% - 16.1%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Injection site pain
|
Injection site pain
|
postmarketing, 0.1% - 12.7%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Chest pain
|
Chest pain
|
postmarketing, 2.3% - 3.7%
|
|
|
|
|
x
|
x
|
x
|
x
|
Haematoma
|
Haematoma
|
postmarketing, 0.0001% - 7.5%
|
|
|
|
|
x
|
|
x
|
x
|
Atrial fibrillation
|
Atrial fibrillation
|
1% - 1.1%
|
|
|
|
|
|
x
|
x
|
|
Vomiting
|
Vomiting
|
postmarketing, 0.1% - 7.86%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Ventricular tachycardia
|
Ventricular tachycardia
|
postmarketing, 0.9% - 1%
|
|
|
|
|
|
|
x
|
x
|
Epistaxis
|
Epistaxis
|
postmarketing, 0.0012% - 1.9%
|
|
|
|
|
|
x
|
x
|
x
|
Angina pectoris
|
Angina pectoris
|
postmarketing, 0.2% - 5.3%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Gingival bleeding
|
Gingival bleeding
|
postmarketing, 0.12% - 1.5%
|
|
|
|
|
|
|
x
|
x
|
Melaena
|
Melaena
|
0.22% - 0.4%
|
|
|
|
|
|
x
|
x
|
|
Thrombocytopenia
|
Thrombocytopenia
|
postmarketing, 0.3% - 1.1%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Retroperitoneal haemorrhage
|
Retroperitoneal haemorrhage
|
postmarketing, 0.069% - 0.697%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Haemoptysis
|
Haemoptysis
|
postmarketing, 0.0046% - 0.5%
|
|
|
|
|
|
|
x
|
x
|
Haemorrhage intracranial
|
Haemorrhage intracranial
|
postmarketing, 0.0463% - 1%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Anaphylactic shock
|
Anaphylactic shock
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Anaemia
|
Anaemia
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
Arteriovenous fistula
|
Arteriovenous fistula
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Cardiac tamponade
|
Cardiac tamponade
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Compartment syndrome
|
Compartment syndrome
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Connective tissue disorder
|
Connective tissue disorder
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
Contusion
|
Contusion
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Coronary artery thrombosis
|
Coronary artery thrombosis
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Dyspnoea
|
Dyspnoea
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
Dermatitis
|
Rash
|
postmarketing
|
|
|
|
|
|
x
|
x
|
x
|
Rash
|
Rash
|
postmarketing
|
|
|
|
|
|
x
|
x
|
x
|
Eye disorder
|
Eye disorder
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Eye haemorrhage
|
Eye haemorrhage
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Gastrointestinal disorder
|
Gastrointestinal disorder
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
Gastrointestinal haemorrhage
|
Gastrointestinal haemorrhage
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Cardiac disorder
|
Cardiac disorder
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
Haematemesis
|
Haematemesis
|
postmarketing
|
|
|
|
|
x
|
x
|
|
x
|
Haematuria
|
Haematuria
|
postmarketing
|
|
|
|
|
x
|
x
|
|
x
|
Frank hematuria
|
|
|
|
|
|
|
x
|
|
|
Pericardial haemorrhage
|
Pericardial haemorrhage
|
postmarketing
|
|
|
|
|
|
x
|
|
x
|
Peritoneal haemorrhage
|
Peritoneal haemorrhage
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Hypersensitivity
|
Hypersensitivity
|
postmarketing
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
Immune system disorder
|
Immune system disorder
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
Mediastinal disorder
|
Mediastinal disorder
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Myocardial infarction
|
Myocardial infarction
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Acute coronary syndrome
|
Myocardial infarction
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Acute coronary syndrome
|
|
|
|
|
|
|
|
x
|
|
Nervous system disorder
|
Nervous system disorder
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
Reperfusion injury
|
Reperfusion injury
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Shock
|
Shock
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
Syncope
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Thrombosis
|
Thrombosis
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Urethral disorder
|
Urinary tract disorder
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Urinary tract disorder
|
Urinary tract disorder
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Urticaria
|
Urticaria
|
postmarketing
|
|
|
|
|
|
x
|
x
|
x
|
Angiopathy
|
Angiopathy
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
Pulmonary haemorrhage
|
Pulmonary haemorrhage
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Injection site reaction
|
Injection site reaction
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
Haemoglobin decreased
|
Haemoglobin decreased
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Skin disorder
|
Unspecified disorder of skin and subcutaneous tissue
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Oesophageal haemorrhage
|
Oesophageal haemorrhage
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Groin pain
|
Groin pain
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Ear haemorrhage
|
Ear haemorrhage
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Retroperitoneal haematoma
|
Retroperitoneal haematoma
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Anal haemorrhage
|
Anal haemorrhage
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Pharyngeal haemorrhage
|
Pharyngeal haemorrhage
|
postmarketing
|
|
|
|
|
|
|
|
x
|
International normalised ratio increased
|
International normalised ratio increased
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Puncture site reaction
|
Puncture site reaction
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Injection site discomfort
|
Injection site discomfort
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Vascular pseudoaneurysm
|
Vascular pseudoaneurysm
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Thrombosis in device
|
Coronary stent thrombosis
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Catheter thrombosis
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Vessel puncture site haematoma
|
Vessel puncture site haematoma
|
postmarketing
|
|
|
|
|
|
|
|
x
|
Atelectasis
|
Atelectasis
|
|
|
|
|
|
|
x
|
|
|
Pneumothorax
|
Atelectasis
|
|
|
|
|
|
|
x
|
|
|
Coagulopathy
|
Clotting
|
|
|
|
|
|
|
x
|
x
|
x
|
Infection
|
Infection
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Confusional state
|
Confusional state
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Feeling abnormal
|
Confusional state
|
|
|
x
|
x
|
x
|
x
|
|
|
|
VIIth nerve paralysis
|
Facial paralysis
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Oliguria
|
Oliguria
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Petechiae
|
Petechiae
|
|
|
|
|
|
|
x
|
|
|
Pleural effusion
|
Pleural effusion
|
|
|
|
|
|
|
x
|
|
|
Post procedural haemorrhage
|
Postoperative hemorrhage
|
|
|
|
|
|
|
x
|
|
|
Pulmonary oedema
|
Pulmonary oedema
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Renal failure
|
Renal failure
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Dizziness
|
Syncope
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Syncope
|
Syncope
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Loss of consciousness
|
Syncope
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Ventricular fibrillation
|
Ventricular fibrillation
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Injection site haemorrhage
|
Injection site haemorrhage
|
|
|
|
|
|
|
|
x
|
|
Vascular anomaly
|
Vascular anomaly
|
|
|
x
|
x
|
x
|
x
|
|
x
|
|
Sepsis
|
Sepsis
|
|
|
x
|
x
|
x
|
x
|
|
|
|
Increased tendency to bruise
|
Increased tendency to bruise
|
|
|
|
|
|
|
x
|
|
|
Electrocardiogram ST segment elevation
|
Electrocardiogram ST segment elevation
|
|
|
|
|
|
|
|
|
x
|
Surgery
|
Surgical intervention
|
|
|
|
|
|
|
|
x
|
x
|
Drug interaction
|
Drug interaction
|
|
|
|
|
|
|
x
|
|
|
Cerebral ischaemia
|
Cerebral ischaemia
|
|
|
x
|
x
|
x
|
x
|
|
|
|