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Doxorubicin

More information: STITCH, PubChem (stereo-specific compounds: 1, 2, 3) and possibly Wikipedia

ATC Codes: L01DB01, L01DB03

Side effects

Options: Hide MedDRA Preferred Terms ,   display only 20 labels

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 32 33 34 35 36 37
Neutropenia Neutropenia common — 1.6% - 95.8% x x x x x x x x x x x x x x x x x x x x x x x x x x x
Leukopenia Leukopenia uncommon — 1.5% - 98.1% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Alopecia Alopecia common — 6.7% - 95.5% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Alopecia reversible x
Nausea Nausea postmarketing — 0% - 92.4% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Vomiting Vomiting common — 0% - 92.4% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Asthenia Fatigue 0% - 46% x x x x x x x x x x
Asthenia postmarketing — 0% - 51.5% x x x x x x x x x x x x x x x x x x x x x x x x
Fatigue Fatigue 0% - 46% x x x x x x x x x x
Immunodeficiency Immunodeficiency very common x
Opportunistic infection Opportunistic infection very common x x x
Injection site reaction Injection site reaction 2-20% x x x x x x x x x x x x x x x x
Mucosal inflammation Mucosal inflammation postmarketing, 0% - 58.5% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Anaemia Anaemia uncommon — 0% - 72.2% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Neuropathy peripheral Neuropathy peripheral 1% - 45% x x x x x
Neuropathy common, 0.6% - 9.2% x x x x
Neuritis uncommon, 0.8% - 8% x x x
Constipation Constipation very common, 0% - 31% x x x x x x x x x
Amenorrhoea Amenorrhoea 0% - 71.8% x x x x x x x x x x x x x x x x x x x x x x x
Skin discolouration Skin discolouration common, 6.1% x x x x x x x
Pharyngitis Pharyngitis common, 0% - 17.9% x x x x x x x x
Dry skin Dry skin common, 5.5% - 5.9% x x x x x x x
Thrombocytopenia Thrombocytopenia uncommon — 0% - 51.4% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Menopausal symptoms Hot flush postmarketing, 0% - 69.1% x x x x x x x x x x x x x x x x x x x x x x x x x
Hot flush Hot flush postmarketing, 0% - 69.1% x x x x x x x x x x x x x x x x x x x x x x x x x
Dyspepsia Dyspepsia common, 0% - 14% x x x x x x x x
Somnolence Somnolence common, 5.1% x x x x x x x x
Drowsiness x
Hypochromic anaemia Hypochromic anaemia common, 3.5% - 9.6% x x x x x
Anxiety Anxiety common x x x x x
Arthralgia Arthralgia common x x x x
Musculoskeletal discomfort Arthralgia common x x x x
Myalgia common x x x x x x
Back pain Back pain common, 0.9% - 11.7% x x x x x x x x
Cachexia Cachexia common x x x x
Cardiovascular disorder Cardiovascular disorder common x x x x
Chest pain Chest pain common x x x x x x x x
Retrosternal pain x x
Dysphagia Dysphagia common x x x x x x x
Dermatitis exfoliative Dermatitis exfoliative common x x x x x x x
Diarrhoea Diarrhoea postmarketing — 0% - 50.7% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Dysgeusia Dysgeusia common x x x x x x x
Dyspnoea Dyspnoea common, 1% - 23.4% x x x x x x x x x x
Dysuria Dysuria common x x x x x
Epistaxis Epistaxis common x x x x x x x x
Flatulence Flatulence common x x x x
Gastritis Gastritis common x x x x
Gingivitis Gingivitis common x x x x
Headache Headache common, 0% - 14.9% x x x x x x x x
Hyperbilirubinaemia Hyperbilirubinaemia common x x x x x x
Hypertension Hypertension common x x x
Hypotension Hypotension common x x x x x x x x
Orthostatic hypotension Orthostatic hypotension common x x x
Muscle spasms Cramps of lower extremities common x x x x
Muscle spasms postmarketing, common x x x x
Breast pain Breast pain common x x x x x
Hypertonia Hypertonia common x x x x
Musculoskeletal pain Musculoskeletal pain common x x x x
Nasopharyngitis Nasopharyngitis common x x
Pain in extremity Pain in extremity common x x
Paraesthesia Paraesthesia common, 0% - 11.7% x x x x x x x x
Retinitis Retinitis common x x x x x
Skin disorder Skin disorder common x x x x x
Unspecified disorder of skin and subcutaneous tissue postmarketing x x x x x x x x x x x x x
Skin ulcer Skin ulcer common x x x x
Hyperhidrosis Sweating common x x x x x
Upper respiratory tract infection Upper respiratory tract infection common x x x x
Urinary tract infection Urinary tract infection common x x x x x x
Vaginal inflammation Vaginal inflammation common x x x x
Vaginal infection Vaginal inflammation common x x x x
Dry mouth Dry mouth common x x x
Ventricular arrhythmia Ventricular arrhythmia common x x x x x x x
Oedema peripheral Oedema peripheral common x x x x x
Leg edema x x x x
Stomatitis Mouth ulceration common x x x x x x x
Stomatitis postmarketing — 0% - 41.4% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Mouth ulceration Mouth ulceration common x x x x x x x
Ulcerative stomatitis x x
Muscular weakness Muscular weakness common x x x
Myasthenia x x
Bone pain Bone pain common x x x x x
Rash pustular Vesiculobullous rash common x x x x x x
Rash pustular x x
Dermatitis bullous Vesiculobullous rash common x x x x x x
Blister x x x x x x x x
Bullous eruption x x x x
Myalgia Myalgia common x x x x x x
Blood creatinine increased Blood creatinine increased common x x
Serum creatinine increased common x x x
Creatinine increased x
Vision blurred Vision blurred common x x x x
Rash maculo-papular Rash maculo-papular common x x x x x x
Musculoskeletal chest pain Musculoskeletal chest pain common x x
Metastases to liver Metastases to liver common x
Hepatic cancer metastatic Metastases to liver common x
Cough Cough increased common, 0% - 11.5% x x x x x x x
Cough 0% - 12% x x x x x x
Ejection fraction decreased Ejection fraction decreased common x x
Left ventricular ejection fraction decreased x x x
Cardiotoxicity Cardiotoxicity uncommon — 18-65% x x
Acute cardiac toxicity x
Insomnia Insomnia common x x x x x x
Dizziness Dizziness common, 0% - 10.2% x x x x x x x x x x
Syncope x x x x
Mucous membrane disorder Mucous membrane disorder very common, 0% - 14.5% x x x x x x x
Herpes zoster Herpes zoster common, 0% - 9% x x x x x x x x x
Candida infection Oral candidiasis common, 0.8% - 5.6% x x x x x x x
Candida infection x x x x x x
Oral candidiasis Oral candidiasis common, 0.8% - 5.6% x x x x x x x
Eye disorder Eye disorder 3% x x x x x x
Neuralgia Neuralgia 0% - 20% x x x
Oedema Oedema uncommon, common x x x x x x
Weight decreased Weight decreased common, 0% - 4% x x x x x x x x x x
Decreased appetite Anorexia postmarketing — 0% - 21.7% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Decreased appetite x x
Laboratory test abnormal Laboratory test abnormal 0% - 5.8% x
Arrhythmia Arrhythmia 0.5-3% x x x x x x x x x x x x
Infection Infection postmarketing — 0% - 25.9% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Secondary infection x x
Lethargy Lethargy 0% - 72.7% x x x x x x x x x x x x x x x x
Dermatitis Rash postmarketing — 0% - 28.5% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Dermatitis x x x x x
Rash Rash postmarketing — 0% - 28.5% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Eruption x
Febrile neutropenia Febrile neutropenia 0% - 6.1% x x x x x x x x x x x x x x x x x x x x x x
Body temperature increased Body temperature increased postmarketing — 0% - 30.6% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Scrotal erythema Scrotal erythema common, 1% x x
Sepsis Sepsis postmarketing — 0.9% - 1.2% x x x x x x x x x x x x x x x x x x x x x x x x x
Septicemia x x x x x x x x x x x x x x x x
Abdominal pain Abdominal pain postmarketing — 0% - 8.2% x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Gastrointestinal pain Abdominal pain postmarketing — 0% - 8.2% x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Shock Shock postmarketing, 0.9% - 1% x x x x x x x x x x x x x x x x x x x x x x x x x x x
Syncope x x x x
Neuritis Neuritis uncommon, 0.8% - 8% x x x
Peripheral motor neuropathy postmarketing x x
Breast disorder Breast disorder 1% x x x x
Pain Pain postmarketing — 1.2% - 7.4% x x x x x x x x x x x x x x x x x x x x x x x x x x
Stinging x x
Amblyopia Amblyopia uncommon x x
Cardiac failure congestive Cardiac failure congestive uncommon x x x x x x x x x x x x x x x x x x
Nail disorder Nail disorder uncommon x x x x x
Palpitations Palpitations uncommon x x x x x
Rhinitis Rhinitis uncommon x x x x x x
Anaphylactic shock Anaphylactoid reaction uncommon x x x x
Anaphylactic shock postmarketing x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Anaphylactoid reaction Anaphylactoid reaction uncommon x x x x
Abdominal distension Enlargement abdomen uncommon x x x
Pancytopenia Myelosuppression uncommon x x x x x x x x x x x x x x x x x x x x x x x x
Pancytopenia x x
Bone marrow depression x
Cardiomyopathy Cardiomyopathy uncommon x x x x x x x x x x x x x
Ovarian cancer Ovarian cancer uncommon x
Herpes simplex Herpes simplex common, 0% - 6% x x x x x x x
Myelodysplastic syndrome Myelodysplastic syndrome 0.3-0.6% x
Myelodysplasia x
Leukaemia Leukaemia 0% - 1-10% x x x x x x x x x x x x x x x
Leukemia secondary x x x x x x x x x x x x x x
Venous thrombosis Venous thrombosis postmarketing, uncommon x x x
Embolism venous Venous thromboembolism postmarketing, uncommon x
Thromboembolism postmarketing x x x x x x x x x x x x x x x x x
Neoplasm malignant Neoplasm malignant postmarketing x
Coma Coma postmarketing x x x x x
Conjunctivitis Conjunctivitis postmarketing — 0% - 38.4% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Other conjunctivitis x
Connective tissue disorder Connective tissue disorder postmarketing x x x x
Cyst Cyst postmarketing x x
Dehydration Dehydration postmarketing, common x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Toxic epidermal necrolysis Toxic epidermal necrolysis very rare, postmarketing x x x x x
Erythema multiforme Erythema multiforme very rare, postmarketing x x x x x x
Stevens-Johnson syndrome very rare, postmarketing x x x x x
Oesophagitis Oesophagitis postmarketing, common x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Flushing Flushing postmarketing — 1% - 5% x x x x x x x x x x x x x x x x x x x x x x x x x
Gastrointestinal disorder Gastrointestinal disorder postmarketing x x x x x x x x x x x x
Haematochezia Haematochezia postmarketing x x
Blood disorder Blood disorder postmarketing x x
Haemorrhage Haemorrhage postmarketing x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Haemoglobin Haemorrhage postmarketing x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Hypersensitivity Hypersensitivity postmarketing, common x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Immune system disorder Immune system disorder postmarketing x x x x x x x x x x
Keratitis Keratitis postmarketing, 0% - 38.4% x x x x x x x x x x x x x x x x x x x x x x x x
Acute myeloid leukaemia Acute myeloid leukaemia postmarketing x x
Acute leukaemia Acute myeloid leukaemia postmarketing x x
Myeloid leukaemia x
Mediastinal disorder Mediastinal disorder postmarketing x x x x x x x x x x x x x
Oral neoplasm Oral neoplasm postmarketing x x x
Neoplasm Neoplasm postmarketing x
Phlebitis Phlebitis postmarketing — 0.3% - 4.8% x x x x x x x x x x x x x x x x x x x x x
Pneumonia Pneumonia postmarketing, common x x x x x x x x x x x x x x x x
Polyp Polyp postmarketing x x
Pruritus Pruritus postmarketing, common x x x x x x x x x x x x x x x x x x x x x x x x x
Pulmonary embolism Pulmonary embolism postmarketing, uncommon x x x x x x x x x x x x x x
Convulsion Convulsion postmarketing, uncommon x x x x x x x x x
Cardiogenic shock Cardiogenic shock postmarketing x x
Stevens-Johnson syndrome Stevens-Johnson syndrome very rare, postmarketing x x x x x
Embolism Thromboembolism postmarketing x x x x x x x x x x x x x x x x x
Thrombophlebitis Thrombophlebitis postmarketing, uncommon x x x x x x x x x x x x x x x x x x x x x x x x
Ulcer Ulcer postmarketing x x x x x x x x x x x x x x x x x x x x x x x
Erythema Erythema postmarketing x x x x x x x x x x x x x x x x x x x x x
Redness x
Urethral disorder Urinary tract disorder postmarketing x x x x x x x x x x x
Urinary tract disorder Urinary tract disorder postmarketing x x x x x x x x x x x
Urticaria Urticaria postmarketing x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Angiopathy Angiopathy postmarketing x x x x x x x x x x x x
Weight increased Weight increased postmarketing x x x x x x x x
Chills Chills postmarketing — 0.3% - 6.4% x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Rigors x
Burning sensation Burning sensation postmarketing x x x x x x x x x x x x x x x x x x x
Aspartate aminotransferase increased Aspartate aminotransferase increased postmarketing — common x x x x x
Alanine aminotransferase increased Alanine aminotransferase increased postmarketing, common x x x x x x
Malnutrition Malnutrition postmarketing x x x x x x x x x x x x x x x
Skin hyperpigmentation Skin hyperpigmentation postmarketing x x x x x x x x x x x x x x x x x x x x x x x x x x x x x x
Malaise Malaise postmarketing — 0.4% - 4.8% x x x x x x x x x x x x x x x x x x x x x
Discomfort Malaise postmarketing — 0.4% - 4.8% x x x x x x x x x x x x x x x x x x x x x
Feeling abnormal Malaise postmarketing — 0.4% - 4.8% x x x x x x x x x x x x x x x x x x x x x
Confusional state x x x x x
Ill-defined disorder Malaise postmarketing — 0.4% - 4.8% x x x x x x x x x x x x x x x x x x x x x
Peripheral motor neuropathy Peripheral motor neuropathy postmarketing x x
Palmar-plantar erythrodysaesthesia syndrome Acral erythema postmarketing x x x x x x x
Hand and foot syndrome secondary to sickle cell anaemia x x
Caecitis Caecitis postmarketing x x
Phlebosclerosis Phlebosclerosis postmarketing x x x x x x
Tumour necrosis Tumour necrosis postmarketing, uncommon x x x
Gastritis erosive Gastric erosions postmarketing x x x x x
Photosensitivity reaction Photosensitivity postmarketing x x x x x x x x x x x x x x x x x x x x x x x x x
Chemical cystitis Chemical cystitis postmarketing x x x x x x x x x x x
Lacrimation increased Lacrimation postmarketing, common x x x x x x x x x x x x x x x
Embolism arterial Embolism arterial postmarketing x x x x x x x
Blood uric acid increased Hyperuricaemia postmarketing x x x x x x x x x x x x x x x x x
Hyperuricaemia Hyperuricaemia postmarketing x x x x x x x x x x x x x x x x x
Infestation Infestation NOS postmarketing x x x x x x x x x x x x x
Necrotising colitis Necrotising colitis postmarketing x x
Recall phenomenon Radiation recall reaction (dermatologic) postmarketing x x x x x x x x x x x x x x x x x x x x x x x x
Abscess Abscess x x
Lactic acidosis Lactic acidosis x
Agranulocytosis Agranulocytosis x x x x
Albuminuria Albuminuria x x x
Aplastic anaemia Aplastic anaemia x
Angina pectoris Angina pectoris x
Anuria Anuria x
Ascites Ascites x x x
Asthma Asthma x x x x
Ataxia Ataxia x
Atrioventricular block Atrioventricular block x x x x x x
Azoospermia Azoospermia x x x x x x x x x
Oligospermia x x x x
Balanitis Balanitis x x
Mental disorder Mental disorder x x x
Blister Blister x x x x x x x x
Bone disorder Bone disorder x x
Bronchitis Bronchitis x x
Bundle branch block Bundle branch block x x x x x x x x x x x x x x x x
Skin candida Skin candida x x
Vulvovaginal candidiasis Vaginal moniliasis x x x
Vulvovaginal mycotic infection Vaginal moniliasis x x x
Congestive cardiomyopathy Congestive cardiomyopathy x
Cellulitis Cellulitis x x x x x x x x x x x
Neck pain Neck pain x
Cholangitis sclerosing Cholangitis sclerosing x x
Colitis Colitis x x x x x
Confusional state Confusional state x x x x x
Cryptococcosis Cryptococcosis x x x x
Cystitis Cystitis x x
Bladder pain Cystitis x x
Cystitis noninfective Cystitis x x
Delirium Delirium x x
Drug eruption Drug eruption x
Dermatitis atopic Dermatitis atopic x x
Dermatitis contact Dermatitis contact x
Fungal skin infection Fungal skin infection x x x
Diabetes mellitus Diabetes mellitus x x
Diplopia Diplopia x
Dysarthria Dysarthria x
Osteoarthritis Dysarthria x
Arthropathy x
Dyskinesia Dyskinesia x
Ecchymosis Ecchymosis x x
Eczema Eczema x
Effusion Effusion x
Eosinophilia Eosinophilia x x
Eructation Eructation x x
Erythema nodosum Erythema nodosum x x
Extravasation Extravasation x x x x x x x x x x x x
Faecalith Faecalith x x
Faecaloma Faecalith x x
Folliculitis Folliculitis x x x x x
Furuncle Furunculosis x x x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage x x x
Gingival bleeding Gingival bleeding x
Glossitis Glossitis x x x x
Glycosuria Glycosuria x x
Cardiac arrest Cardiac arrest x x x
Heart disease congenital Heart malformation x x
Cardiac disorder Cardiac disorder x x x x x
Cardiomegaly Cardiomegaly x x x x
Cardiac failure Cardiac failure x x x x x x
Haematemesis Haematemesis x
Haematuria Haematuria x x x x x
Hemiplegia Hemiplegia x
Haemoptysis Haemoptysis x
Hepatitis Hepatitis x x x x
Hepatomegaly Hepatomegaly x x
Hepatosplenomegaly Hepatosplenomegaly x x
Oral herpes Herpes labialis x x x x
Hiccups Hiccups x x
Hydronephrosis Hydronephrosis x
Hypercalcaemia Hypercalcaemia x x x x
Hyperaesthesia Hyperaesthesia x
Hyperglycaemia Hyperglycaemia x x x
Hyperkalaemia Hyperkalaemia x x x x
Hyperlipidaemia Hyperlipidaemia x x
Hypernatraemia Hypernatraemia x x
Hyperventilation Hyperventilation x x
Hypoaesthesia Hypoaesthesia x x x
Hypocalcaemia Hypocalcaemia x x x x
Hypoglycaemia Hypoglycaemia x x
Hypokalaemia Hypokalaemia x x x x x x x
Hyponatraemia Hyponatraemia x x x x x
Hypoproteinaemia Hypoproteinaemia x x
Body temperature decreased Body temperature decreased x x
Hypothermia Body temperature decreased x x
Immunology test Immune status x
Inflammation Inflammation x
Influenza Influenza x x
Jaundice Jaundice x x x
Jaundice cholestatic Jaundice cholestatic x x
Arthropathy Arthropathy x
Ketosis Ketosis x x
Renal failure acute Renal failure acute x x
Laryngitis Laryngitis x
Acute lymphocytic leukaemia Acute lymphocytic leukaemia x x x x x x x x x x x x x
Myeloid leukaemia Myeloid leukaemia x
Leukoplakia oral Leukoplakia oral x x
Vaginal discharge Leukorrhea x
Lung disorder Lung disorder x
Lymphangitis Lymphangitis x x
Lymphoedema Lymphoedema x x
Lymphopenia Lymphopenia x x x
Mastitis Mastitis x
Melaena Melaena x x
Premature menopause Premature menopause x
Multi-organ failure Multi-organ failure x
Hypotonia Hypotonia x x
Muscle relaxant therapy Hypotonia x x
Fungal infection Fungal infection x x x x
Myocarditis Myocarditis x x x
Myositis Myositis x x
Necrosis Necrosis x x x x x x x x x x x x x x
Nervous system disorder Nervous system disorder x x x x
Nervousness Nervousness x x
Tension Nervousness x x
Nocturia Nocturia x
Nystagmus Nystagmus x
Oliguria Oliguria x x
Optic neuritis Optic neuritis x x x x x
Otitis media Otitis media x x
Pancreatitis Pancreatitis x x
Pelvic pain Pelvic pain x
Drug hypersensitivity Penicillin allergy x x x
Pericardial effusion Pericardial effusion x x x x x x
Pericarditis Pericarditis x x x
Tooth abscess Abscess periodontal x
Petechiae Petechiae x x x x
Pleural effusion Pleural effusion x x x x
Pneumothorax Pneumothorax x x
Supraventricular extrasystoles Supraventricular extrasystoles x
Proctitis Proctitis x
Prostatic disorder Prostatic disorder x
Psoriasis Psoriasis x x
Pulmonary oedema Pulmonary oedema x x
Purpura Purpura x x
Vascular purpura Purpura x x
Radiation injury Radiation injury x x
Anorectal disorder Rectal disorder x
Renal failure Renal failure x x
Scotoma Scotoma x
Seborrhoeic dermatitis Seborrhoeic dermatitis x
Septic shock Septic shock x x x x x x x x x x x x
Salivary hypersecretion Salivary hypersecretion x
Sinusitis Sinusitis x x x x
Skin mass Skin nodule x
Gastric ulcer Gastric ulcer x
Aphthous stomatitis Aphthous stomatitis x x x x x
Cerebrovascular accident Cerebrovascular accident x
Syncope Syncope x x x x
Loss of consciousness Syncope x x x x
Tachycardia Tachycardia x x x x x x x x x
Sinus tachycardia Sinus tachycardia x x x x x
Testicular disorder Testicular disorder x
Thrombosis Thrombosis x x x x
Tinnitus Tinnitus x x
Toxoplasmosis Toxoplasmosis x x x x
Tumour lysis syndrome Tumour lysis syndrome x x x x x
Ureteric obstruction Ureteric obstruction x
Urethral obstruction Urethral obstruction x
Pollakiuria Pollakiuria x
Vasodilation procedure Vasodilation x x
Ventricular tachycardia Ventricular tachycardia x x x x x x x x x
Vertigo Vertigo x x
Viral infection Viral infection x x
Tachyarrhythmia Tachyarrhythmia x x x x x x
Peripheral vascular disorder Peripheral vascular disorder x
Hepatic failure Hepatic failure x x
Agitation Agitation x
Mood swings Mood swings x x x
Affect lability Mood swings x x x
Onycholysis Onycholysis x x x
Hypochloraemia Hypochloraemia x
Hyperphosphataemia Hyperphosphataemia x
Hypophosphataemia Hypophosphataemia x x
Cystitis haemorrhagic Cystitis haemorrhagic x x
Hypokinesia Hypokinesia x x
Hepatic function abnormal Hepatic function abnormal x x
Migraine Migraine x x
Peripheral sensory neuropathy Peripheral sensory neuropathy x x
Blood urea increased Blood urea increased x
Diarrhoea haemorrhagic Diarrhoea haemorrhagic x
Generalised oedema Generalised oedema x
Fluid retention Generalised oedema x
Oedema genital Oedema genital x x
Ventricular extrasystoles Ventricular extrasystoles x x x x
Injection site haemorrhage Injection site haemorrhage x x
Hypermagnesaemia Hypermagnesaemia x
Hypomagnesaemia Hypomagnesaemia x x x x
Injection site inflammation Injection site inflammation x
Renal impairment Kidney function abnormal x x
Blood lactate dehydrogenase increased Lactic dehydrogenase activity increased x x
Hepatocellular injury Hepatocellular injury x
Liver injury Hepatocellular injury x
Liver function test abnormal Liver function test abnormal x
Skin necrosis Skin necrosis x x x x x
Skin exfoliation Skin necrosis x x x x x
Skin scaly x x x x
Eye pain Eye pain x x
Injection site pain Injection site pain x x
Blood alkaline phosphatase increased Phosphatase alkaline increased x x x
Prothrombin level increased Prothrombin level increased x x x
Hyporeflexia Hyporeflexia x
Blood thromboplastin decreased Thromboplastin decreased x
Oesophageal ulcer Oesophageal ulcer x x
Polyneuropathy Polyneuropathy x x
Leukoderma Leukoderma x
Pseudolymphoma Pseudolymphoma x
Injection site infection Injection site infection x x
Oral pain Oral pain x x x x
Dyspnoea exertional Dyspnoea exertional x x
Heart sounds abnormal Gallop rhythm x x
Increased appetite Increased appetite x x
Abdominal pain upper Abdominal pain upper x x
Proctalgia Rectal tenesmus x x
Rectal tenesmus Rectal tenesmus x x
Anorectal discomfort Rectal tenesmus x x
Thinking abnormal Thinking abnormal x x
Mental disability Thinking abnormal x x
Abnormal dreams Abnormal dreams x
Rash erythematous Rash erythematous x x x x
Neurotoxicity Neurotoxicity x x x
Gravitational oedema Gravitational oedema x
Urine abnormality Urine abnormality x
Urine analysis abnormal Urine abnormality x
Ventricular dysfunction Ventricular dysfunction x x
Rectal haemorrhage Rectal haemorrhage x x
Hepatobiliary disease Hepatobiliary disease x
Dry eye Dry eye x x
Hypolipidaemia Hypolipidaemia x
Red blood cell abnormality Red blood cell abnormality x
Feeling hot Warmth x
Dysaesthesia Dysaesthesia 0% - 10% x x x
Electrocardiogram QRS complex abnormal QRS voltage decreased x x x
Bradycardia Bradycardia x x x x x x x x x x x
Transaminases increased Transaminases increased x x
Blindness Blindness x x
Lymphadenopathy Lymphadenopathy x x
Electrocardiogram ST segment depression Electrocardiogram ST segment depression x x x x
Coordination abnormal Coordination abnormal x
Influenza like illness Influenza like illness x x
Paralysis Paralysis x
Face oedema Face oedema x x x x
Gait disturbance Gait disturbance x x
Drug interaction Drug interaction x
Blood bilirubin increased Bilirubin total increased x
Serum bilirubin increased x x
Thrombocytosis Thrombocytosis x x x
Hand and foot syndrome secondary to sickle cell anaemia Hand and foot syndrome secondary to sickle cell anaemia x x
Local reaction Local reaction x x x
Bladder stenosis Bladder constriction x x x x
Neutropenic sepsis Neutropenic sepsis x x
Gastrointestinal toxicity Gastrointestinal toxicity x
Ileus Ileus x x x
Pigmentation disorder Abnormal pigmentation x x x
Ocular toxicity Ocular toxicity x
Urine output Urine output x x
Sensitisation Sensitisation x x
Parosmia Parosmia x
Rash papular Rash papular x x
Dysphonia Dysphonia x
Pneumocystis jirovecii pneumonia Pneumocystis jirovecii pneumonia x x
Ageusia Ageusia x
Proctitis ulcerative Proctitis ulcerative x x
Metastatic neoplasm Metastatic neoplasm x x
Metastatic disease x x x
Vaginal haemorrhage Vaginal haemorrhage x
Visual impairment Abnormal vision x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Indication Labels
Acquired immunodeficiency syndrome x x x x x x
Acute leukaemia x x
Acute lymphocytic leukaemia x x x x x x x x x
Acute myeloid leukaemia x x x x x x x x x
Advanced breast cancer x x x
Bladder cancer x x x
Bladder cancer stage IV x
Bladder carcinoma x x x
Bladder neoplasm x x
Bladder transitional cell carcinoma x x
Bladder transitional cell carcinoma metastatic x x
Bone sarcoma x x
Brain neoplasm x x
Breast cancer x x x x x x x x x x x x x x x x x x x x x x x
Breast cancer stage IV x x x x x x x x x
Bronchial carcinoma x x x x x x x
Carcinoma x x x x x x x
Carcinoma breast x x x x x x x x x
Carcinoma of lung x x x
Carcinoma stomach x x x x x x x x x x
Carcinoma testes x x
Cardiac disorder x
Cardiotoxicity x x x x
Drug interaction x
Endometrial cancer x x
Ewing's sarcoma x x x
Generalized illness x x
Hepatic function abnormal x
Hepatocellular carcinoma x x x x
Hodgkin's disease x x x x x x x x x x x
Hypersensitivity x
Immunodeficiency x
Kaposi's sarcoma x
Kaposi's sarcoma AIDS related x x x x x x x
Leukaemia x x
Lymphoma x x x x x x x x x x
Malignant melanoma x x x
Menopause x x
Metastases to liver x x x
Metastasis x x x
Metastatic carcinoma x x
Metastatic gastric adenocarcinoma x x
Neoplasm x x x x x x x x x x x x x x x x x x x x x x
Neoplasm malignant x x x x x x x x x x x x x
Nephroblastoma x x x x x x x x x
Neuroblastoma x x x x x x x x x x
Node-positive breast cancer x x
Non-Hodgkin's lymphoma x x x x x x x x x x x
Non-small cell lung cancer x x x
Osteosarcoma x x
Ovarian cancer x x x x x x x x
Ovarian carcinoma x x x x x x x x
Ovarian epithelial cancer x x x x
Ovarian epithelial cancer stage IV x x
Pancreatic carcinoma x
Plasma cell myeloma x x x x x x x x
Prostate cancer x
Prostate carcinoma x x x
Renal carcinoma x x
Rhabdomyosarcoma x x
Sarcoma x x x x x x x x x x x x x x
Small cell lung cancer x x x x x
Solid tumour x x x x
Squamous cell carcinoma x x
Thymoma x
Thyroid carcinoma x x x x x x x x x x

doxorubicin / doxorubicin hydrochloride

Side effects:44
Source:EMA

Doxorubicin

Side effects:49
Source:BC Cancer

WARNINGS / ADRIAMYCIN Solution for Injection

Side effects:59
Source:medicines.org.au

Epirubicin

Side effects:61
Source:BC Cancer

DOXORUBICIN

Side effects:40
Source:FDA Structured Product Label

DOXORUBICIN

Side effects:55
Source:FDA Structured Product Label

doxorubicin

Side effects:55
Source:FDA Structured Product Label

epirubicin

Side effects:42
Source:FDA Structured Product Label

epirubicin

Side effects:42
Source:FDA Structured Product Label

EPIRUBICIN HYDROCHLORIDE / ELLENCE

Side effects:42
Source:FDA

EPIRUBICIN

Side effects:44
Source:FDA Structured Product Label

epirubicin

Side effects:44
Source:FDA Structured Product Label

epirubicin hydrochloride / Ellence

Side effects:49
Source:FDA

EPIRUBICIN HYDROCHLORIDE / PHARMORUBICIN PFS

Side effects:51
Source:Health Canada

EPIRUBICIN

Side effects:64
Source:FDA Structured Product Label

epirubicin

Side effects:65
Source:FDA Structured Product Label

EPIRUBICIN

Side effects:66
Source:FDA Structured Product Label

EPIRUBICIN

Side effects:66
Source:FDA Structured Product Label

EPIRUBICIN

Side effects:66
Source:FDA Structured Product Label

Powder for Injection / PHARMORUBICIN RD

Side effects:81
Source:medicines.org.au

DOXORUBICIN HYDROCHLORIDE / MYOCET

Side effects:60
Source:Health Canada

DOXORUBICIN

Side effects:93
Source:FDA Structured Product Label

doxorubicin

Side effects:104
Source:FDA Structured Product Label

DOXORUBICIN

Side effects:93
Source:FDA Structured Product Label

doxorubicin / doxorubicin hydrochloride

Side effects:182
Source:EMA

DOXORUBICIN HYDROCHLORIDE / DOXIL

Side effects:232
Source:FDA

DOXORUBICIN HYDROCHLORIDE / CAELYX

Side effects:261
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label