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Estramustine

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: L01XX11

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Tenderness Tenderness 64% - 66% x
Libido decreased Libido decreased 20-50% x
Disturbance in sexual arousal Libido decreased 20-50% x
Oedema Oedema 17% - 19% x x
Diarrhoea Diarrhoea 11% - 12% x x
Nausea Nausea 8% - 15% x x
Muscle spasms Cramps of lower extremities 8% - 11% x
Abdominal discomfort Gastrointestinal tract irritation 6% - 11% x
Gastrointestinal tract irritation Gastrointestinal tract irritation 6% - 11% x
Dyspnoea Dyspnoea 3% - 11% x
Thrombophlebitis Thrombophlebitis 3% - 7% x
Decreased appetite Anorexia 3% - 4% x
Lethargy Lethargy 3% - 4% x
Leukopenia Leukopenia 2% - 4% x
Dermatitis Rash 1% - 4% x x
Rash Rash 1% - 4% x x
Cardiac failure congestive Cardiac failure congestive 2% - 3% x x
Myocardial infarction Myocardial infarction 1% - 3% x
Acute coronary syndrome Myocardial infarction 1% - 3% x
Pruritus Pruritus 2% x
Thrombocytopenia Thrombocytopenia 1% - 2% x
Increased tendency to bruise Increased tendency to bruise 0% - 3% x
Insomnia Insomnia 0% - 3% x
Alopecia Alopecia 1% x
Chest pain Chest pain 1% x
Depression Depression 0% - 2% x
Flatulence Flatulence 0% - 2% x
Headache Headache 1% x
Cardiac arrest Cardiac arrest 0% - 2% x
Cerebrovascular accident Cerebrovascular accident 0% - 2% x
Vomiting Vomiting 1% x x
Mood swings Mood swings 0% - 2% x
Affect lability Mood swings 0% - 2% x
Dry skin Dry skin 0% - 2% x
Lacrimation increased Lacrimation 1% x
Anxiety Anxiety 0% - 1% x
Flushing Flushing 0% - 1% x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage 0% - 1% x
Dysphonia Hoarseness 0% - 1% x
Hypercalcaemia Hypercalcaemia 0% - 1% x
Night sweats Night sweats 0% - 1% x
Thirst Thirst 0% - 1% x
Tinnitus Tinnitus 0% - 1% x
Eye pain Eye pain 0% - 1% x
Skin exfoliation Skin exfoliation 0% - 1% x
Throat irritation Burning in throat 0% - 1% x
Menopausal symptoms Hot flush 0% - 1% x
Hot flush Hot flush 0% - 1% x
Congenital anomaly Congenital anomaly x
Developmental delay Congenital anomaly x
Gynaecomastia Gynaecomastia x
Hypernatraemia Hypernatraemia x
Embolism Thromboembolism x
Embolism venous Thromboembolism x
Glucose tolerance decreased Glucose tolerance decreased x
Erectile dysfunction Erectile dysfunction x
Pancytopenia Myelosuppression x
Liver function test abnormal Raised liver function tests x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Estramustine

Side effects:14
Source:BC Cancer

ESTRAMUSTINE

Side effects:42
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label