Estramustine phosphate sodium

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

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MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2
Alopecia def Alopecia def x
Anaemia def Anaemia def x
Angioedema def Angioedema def x
Decreased appetite Anorexia def x
Anxiety def Anxiety def x
Chest pain def Chest pain def x
Confusional state def Confusional state def x
Feeling abnormal Confusional state def x
Libido decreased def Libido decreased def x
Disturbance in sexual arousal Libido decreased def x
Diarrhoea def Diarrhoea def x x
Polyuria def Diuresis def x
Dyspnoea def Dyspnoea def x
Oedema def Oedema def x x
Dermatitis def Rash def x x
Rash def Rash def x x
Flatulence def Flatulence def x
Flushing def Flushing def x
Gastrointestinal haemorrhage def Gastrointestinal haemorrhage def x
Gynaecomastia def Gynaecomastia def x
Headache def Headache def x x
Cardiac arrest def Cardiac arrest def x
Cardiac disorder def Cardiac disorder def x
Cardiac failure def Cardiac failure def x x
Cardiac failure congestive def Cardiac failure congestive def x x
Haemorrhage def Haemorrhage def x
Haemoglobin def Haemorrhage def x
Dysphonia def Hoarseness def x
Hypercalcaemia def Hypercalcaemia def x
Hypertension def Hypertension def x
Hypertrophy def Hypertrophy def x
Infarction def Infarction def x x
Muscle spasms def Cramps of lower extremities x
Cramp muscle def x
Lethargy def Lethargy def x x
Leukopenia def Leukopenia def x x
Myocardial infarction def Myocardial infarction def x x
Acute coronary syndrome def Myocardial infarction def x x
Nausea def Nausea def x x
Night sweats def Night sweats def x
Pain def Pain def x
Pruritus def Pruritus def x
Cerebrovascular accident def Cerebrovascular accident def x
Hyperhidrosis def Sweating def x
Thirst def Thirst def x
Thrombocytopenia def Thrombocytopenia def x x
Embolism def Thromboembolism def x
Embolism venous Thromboembolism def x
Thrombophlebitis def Thrombophlebitis def x
Tinnitus def Tinnitus def x
Vomiting def Vomiting def x x
Mood swings Mood swings x
Affect lability Mood swings x
Myocardial ischaemia def Myocardial ischaemia def x
Muscular weakness def Muscular weakness def x
Eye pain def Eye pain def x
Dry skin def Dry skin def x
Tenderness def Tenderness def x
Skin exfoliation Skin exfoliation x
Localized exfoliation def x
Fluid retention Fluid retention x
Balance disorder Disequilibrium syndrome x
Lacrimation increased def Lacrimation def x
Increased tendency to bruise Increased tendency to bruise x
Gastrointestinal disorder def Gastrointestinal symptom NOS x
Transaminases increased Transaminases increased x
Menopausal symptoms def Hot flush def x
Hot flush def Hot flush def x
Emotional distress def Emotional distress def x
Insomnia def Insomnia def x
Asthenia def Weakness def x
Abdominal discomfort Gastrointestinal tract irritation x
Gastrointestinal tract irritation Gastrointestinal tract irritation x
Indication Labels
Carcinoma def x
Prostate carcinoma def x
Prostatic disorder def x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01XX11

Legend

Color scheme: standard – alternative

100%    
75%    
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frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. ESTRAMUSTINE PHOSPHATE SODIUM / EMCYT : 28 side effects (Health Canada)
  2. ESTRAMUSTINE PHOSPHATE SODIUM / EMCYT : 49 side effects (Drugs@FDA)