Fosamax

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels (show all 24)
1 2 3 4 5 6 7 8 9 10
Gastrooesophageal reflux disease def Gastrooesophageal reflux disease def 0.7% - 2.8% 0% - 3.2% x x
Melaena def Melaena def 0% - 1.3% 0% - 0.6% x x x x x x x
Gastric ulcer def Gastric ulcer def 0% - 1.1% x x x x x x x
Myalgia def Myalgia def postmarketing, 0.2% x x x x x x x x
Musculoskeletal discomfort Myalgia def postmarketing, 0.2% x x x x x x x x
Alopecia def Alopecia def postmarketing
Anaemia def Anaemia def postmarketing x
Angioedema def Angioedema def postmarketing x x x x x x x x x
Asthenia def Asthenia def postmarketing x
Neoplasm malignant def Neoplasm malignant def postmarketing x
Duodenal ulcer def Duodenal ulcer def postmarketing x x x x x x x x x
Oedema def Oedema def postmarketing x x
Toxic epidermal necrolysis def Toxic epidermal necrolysis def postmarketing x x x x x x x
Necrolysis epidermal postmarketing x x x x x x
Episcleritis Episcleritis postmarketing x x
Oesophageal stenosis def Oesophageal stenosis def postmarketing x x x x x x x x x
Oesophagitis def Oesophagitis def postmarketing x x x x x x x x x
Body temperature increased def Body temperature increased def postmarketing x x x x x x x x
Hypersensitivity def Hypersensitivity def postmarketing x x x x x x x x x
Hypocalcaemia def Hypocalcaemia def postmarketing x x x x x x x x
Infection def Infection def postmarketing x x x x x
Leukaemia def Leukaemia def postmarketing x x x x x
Oral disorder def Oral disorder def postmarketing x
Musculoskeletal pain def Musculoskeletal pain def postmarketing x x x x x x
Osteomyelitis def Osteomyelitis def postmarketing
Osteonecrosis def Osteonecrosis def postmarketing x x x x x x
Pruritus def Pruritus def postmarketing x x x x x x
Scleritis def Scleritis def postmarketing x x x x x x
Swelling def Swelling def postmarketing x x
Urticaria def Urticaria def postmarketing x x x x x x x x x
Uveitis def Uveitis def postmarketing x x x x x x x
Vertigo def Vertigo def postmarketing x x
Oedema peripheral def Oedema peripheral def postmarketing x x
Impaired healing Impaired healing postmarketing x x x x
Joint swelling Joint swelling postmarketing x x
Malaise def Malaise def postmarketing x x x x x x x x
Discomfort def Malaise def postmarketing x x x x x x x x
Feeling abnormal Malaise def postmarketing x x x x x x x x
Ill-defined disorder Malaise def postmarketing x x x x x x x x
Erosive oesophagitis Esophageal erosions postmarketing x x x x x x x x x
Photosensitivity reaction def Photosensitivity def postmarketing x x x x x x x
Transaminases increased Transaminases increased postmarketing x x x x
Osteonecrosis of jaw def Osteonecrosis of jaw def postmarketing x x x x x x
Gastrointestinal disorder def Gastrointestinal disorder def x x x x
Haemorrhage def Haemorrhage def x x x x x x x x
Haemoglobin def Haemorrhage def x x x x x x x x
Influenza def Influenza def
Lymphopenia def Lymphopenia def
Osteogenesis imperfecta def Osteogenesis imperfecta def
Osteomalacia def Osteomalacia def x
Peptic ulcer def Peptic ulcer def x x x x x x x x
Endometrial sarcoma Endometrial stromal sarcoma def
Anastomotic ulcer Anastomotic ulcer x x x x x x x x
Calcinosis def Deposit calcium def x
Indication Labels
Abdominal distension def x
Abdominal pain def x
Adverse event def x
Adverse reaction def x
Bone disorder def x x x x x x x
Compression fracture def x x x x x x x x x x
Constipation def x
Cramp muscle def x
Diarrhoea def x
Distention def x
Dizziness def x
Drug interaction def x
Dysgeusia def x
Dyspepsia def x
Dysphagia def x
Erythema def x
Flatulence def x
Gastritis def x
Glucocorticoid therapy x
Headache def x
Menopause def x x x x x x x
Nausea def x
Oesophageal disorder def x
Oesophageal ulcer def x
Osteopenia def x x x x x x x
Osteoporosis def x x x x x x x x x x
Osteoporosis postmenopausal def x x x x x x x x x
Osteoporotic fracture def x x x x x x x x x
Pain def x
Premature menopause def x x x x x x x
Rash def x
Regurgitation def x
Ulcer def x
Vomiting def x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: M05BA04

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. alendronate sodium / FOSAMAX : 3 side effects (FDA MedWatch)
  2. ALENDRONATE SODIUM / FOSAMAX : 13 side effects (Drugs@FDA)
  3. alendronate sodium / Fosamax : 18 side effects (FDA MedWatch)
  4. ALENDRONIC ACID (ALENDRONATE SODIUM) / PHL-ALENDRONATE-FC : 23 side effects (Health Canada)
  5. alendronate sodium / Fosamax : 23 side effects (FDA MedWatch)
  6. ALENDRONIC ACID (ALENDRONATE SODIUM TRIHYDRATE) / GEN-ALENDRONATE : 27 side effects (Health Canada)
  7. ALENDRONIC ACID (ALENDRONATE SODIUM TRIHYDRATE) / RIVA ALENDRONATE : 27 side effects (Health Canada)
  8. ALENDRONIC ACID (ALENDRONATE SODIUM) / APO-ALENDRONATE : 30 side effects (Health Canada)
  9. ALENDRONIC ACID (ALENDRONATE SODIUM TRIHYDRATE) / GEN-ALENDRONATE : 32 side effects (Health Canada)
  10. ALENDRONATE SODIUM / FOSAMAX : 36 side effects (Drugs@FDA)