Lisinopril

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels (show all 40)
1 2 3 4 5 6 7 8 9 10
Headache def Headache def 5.7% 1.9% x x x x x x x x
Dizziness def Dizziness def 5.4% 1.9% x x x x x x x x
Syncope def postmarketing x x x x x x x x
Diarrhoea def Diarrhoea def 2.7% - 3.7% 1.9% - 2.4% x x x x x x x x
Cough def Cough def postmarketing, 3.5% 1% x x x x x x x x x
Asthenia def Fatigue def 2.5% 1% x x x x x x x x
Asthenia def 1.3% 1% x x x x x x x x x
Fatigue def Fatigue def 2.5% 1% x x x x x x x x
Nausea def Nausea def 2% 2.4% x x x x x x x x
Dermatitis def Rash def 0.6% - 1.7% 0.5% - 0.6% x x x x x x x
Rash def Rash def 0.6% - 1.7% 0.5% - 0.6% x x x x x x x
Vomiting def Vomiting def 1.1% 0.5% x x x x x x x
Erectile dysfunction def Erectile dysfunction def 1% 0% x x x x x
Dyspepsia def Dyspepsia def 0.9% 0% x x x x x x x
Heartburn def x x x x x x
Paraesthesia def Paraesthesia def 0.8% 0% x x x x x x x x
Influenza def Influenza def 0.3% 0% x x x x x
Vertigo def Vertigo def 0.2% 0% x x x x x x
Anaemia def Anaemia def postmarketing, rare x x x x x x x x
Haemolytic anaemia def Haemolytic anaemia def postmarketing, rare x x x x x x x
Anuria def Anuria def rare x x x x x x x
Bronchospasm def Bronchospasm def rare x x x x x x x
Oedema def Oedema def rare x x x x x x x x
Toxic epidermal necrolysis def Toxic epidermal necrolysis def rare x x x x x x
Necrolysis epidermal rare x x x x x x
Erythema multiforme def Erythema multiforme def rare
Hepatitis def Hepatitis def rare x x x x x x
Hyperkalaemia def Hyperkalaemia def postmarketing x x x x x x x
Hypersensitivity def Hypersensitivity def rare
Hypoglycaemia def Hypoglycaemia def rare x x x x
Hyponatraemia def Hyponatraemia def postmarketing, rare x x
Renal failure acute def Renal failure acute def rare x x x x x x
Leukopenia def Leukopenia def rare x x x x x x x x
Neutropenia def Neutropenia def rare x x x x x x x x
Oliguria def Oliguria def rare x x x x x x x
Pancreatitis def Pancreatitis def rare x x x x x x
Pemphigus def Pemphigus def rare x x x x x x
Renal artery stenosis Renal artery stenosis postmarketing x x x
Sinusitis def Sinusitis def rare x x x x x x x
Arterial stenosis def Arterial stenosis def postmarketing x x x
Shock def Syncope def postmarketing x x x x x x x x
Shock def x x
Syncope def Syncope def postmarketing x x x x x x x x
Loss of consciousness def Syncope def postmarketing x x x x x x x x
Thrombocytopenia def Thrombocytopenia def rare x x x x x x
Erythema def Erythema def rare x x x x x x
Azotaemia def Uremia def rare x x x x x x x
Azotaemia def x x x x x x x
Dry mouth def Dry mouth def rare x x x x x
Hepatic failure def Hepatic failure def postmarketing x x x x
Pancytopenia def Bone marrow depression def rare x x x x x x x x
Cytopenia def x
Face oedema def Face oedema def rare x x x x x
Hyperhidrosis def Sweating increased rare x x x x x x
Abdominal pain def Abdominal pain def x x x x x
Gastrointestinal pain def Abdominal pain def x x x x x
Alopecia def Alopecia def x x x x x x
Angina pectoris def Angina pectoris def x x x x x x x x
Decreased appetite Anorexia def x x x x x x x x
Arrhythmia def Arrhythmia def x x x x x
Arthralgia def Arthralgia def x x x x x x x
Coxalgia x x x x x x x
Knee pain x x x x x x x
Musculoskeletal discomfort Arthralgia def x x x x x x x
Myalgia def x x x x x x
Arthritis def Arthritis def x x x x x x x
Asthma def Asthma def x x x x x x x
Ataxia def Ataxia def x x x x x x x
Atrial fibrillation def Atrial fibrillation def x x x x x
Atrial flutter def Atrial flutter def x x
Atrioventricular block def Atrioventricular block def x x
Back pain def Back pain def x x x x x x x x x
Low back pain def x x x x x x x
Mental disorder def Mental disorder def
Breast disorder def Breast disorder def
Bronchitis def Bronchitis def x x x x x x x
Transient ischaemic attack def Transient ischaemic attack def x x x x x
Neck pain def Neck pain def x x x x x x x
Chest pain def Chest pain def x x x x x x x x
Chest discomfort x x x x x x
Nasopharyngitis def Common cold def x x x x
Rhinorrhoea def x x x x x x x
Rhinitis def Common cold def x x x x
Rhinitis def x x x x x x x
Confusional state def Confusional state def x x x x x x x
Feeling abnormal Confusional state def x x x x x x x
Malaise def x x x x x x x x
Constipation def Constipation def x x x x x x x x
Libido decreased def Libido decreased def x x x x x x
Disturbance in sexual arousal Libido decreased def x x x x x x
Dehydration def Dehydration def x x x x x x x
Diabetes mellitus def Diabetes mellitus def x x x x x x x
Diplopia def Diplopia def x x x x x x x
Dysgeusia def Dysgeusia def
Dyspnoea def Dyspnoea def x x x x x x x x
Dysuria def Dysuria def x x x x x x
Effusion def Effusion def x x x x x x x
Embolism def Embolism def x x x x x
Eosinophilia def Eosinophilia def x x x x x x
Epistaxis def Epistaxis def x x x x x x x
Body temperature increased def Body temperature increased def x x x x x x x
Flank pain def Flank pain def x x x x x x
Flatulence def Flatulence def x x x x x x x x
Flushing def Flushing def x x x x x x x x
Cardiac flutter Cardiac flutter x x
Gastritis def Gastritis def x x x x x x
Gastrointestinal disorder def Gastrointestinal disorder def
Gout def Gout def x x x x x x x x x
Cardiac arrest def Cardiac arrest def x x x x x x x
Haemoptysis def Haemoptysis def x x x x x x x
Herpes virus infection def Herpes NOS def x x x x x x
Herpes zoster def Herpes zoster def x x x x x x
Orthostatic hypotension def Orthostatic hypotension def x x x x x
Inappropriate antidiuretic hormone secretion def Inappropriate antidiuretic hormone secretion def x
Infection def Infection def x x x x x x x
Irritability def Irritability def x x x x x x x
Jaundice def Jaundice def x x x x x x
Jaundice cholestatic def Jaundice cholestatic def x x x x x x
Laryngeal oedema def Laryngeal oedema def x x x x x x x
Laryngitis def Laryngitis def x x x x x x x
Pain in extremity def Leg pain x x x x x x x x x
Pain in arm x x x x x x x
Leukocytosis def Leukocytosis def x x x x x x
Lung neoplasm def Lung neoplasm def x x x x x x x
Breast pain def Breast pain def x x x x x x
Mediastinal disorder def Mediastinal disorder def
Muscle spasms def Cramp muscle def x x x x x x x x
Muscle spasms def x x x x x x x
Nasal congestion def Nasal congestion def x x x x
Neoplasm def Neoplasm def x x x x x x x
Nervousness def Nervousness def x x x x x x
Tension def Nervousness def x x x x x x
Blood urea increased NPN increased
Pain def Pain def x x x x x x x x
Palpitations def Palpitations def x x x x x x x
Pelvic pain def Pelvic pain def x x x x x x
Neuropathy peripheral def Neuropathy peripheral def x x x x x x x
Neuropathy def x x x x x x x
Pharyngitis def Pharyngitis def x x x x x x x
Pleural disorder def Pleural disorder def x x x x x x x
Pleural effusion def Pleural effusion def x x x x x x x
Pneumonia def Pneumonia def x x x x x x x
Pruritus def Pruritus def x x x x x x x
Psoriasis def Psoriasis def
Pulmonary oedema def Pulmonary oedema def x x x x x x
Pulmonary embolism def Pulmonary embolism def x x x x x
Pulmonary eosinophilia def Pulmonary eosinophilia def x x x x x x
Pyelonephritis def Pyelonephritis def x x x x x x
Respiratory tract infection def Respiratory tract infection def x x
Salivary hypersecretion def Salivation def x x x x x x
Salivary hypersecretion def x x x x x x
Musculoskeletal pain def Shoulder pain def x x x x x x x x x
Skin infection def Skin infection def x x x x x x
Sleep disorder def Sleep disturbance
Cerebrovascular accident def Cerebrovascular accident def x x x x x x x x
Tachycardia def Tachycardia def x x x x x x
Tinnitus def Tinnitus def x x x x x x x
Tremor def Tremor def x x x x x x x
Upper respiratory tract infection def Upper respiratory tract infection def x x
Urinary tract infection def Urinary tract infection def x x x x x
Urethral disorder def Urinary tract disorder def
Urinary tract disorder def Urinary tract disorder def
Urticaria def Urticaria def x x x x x x
Vasculitis def Vasculitis def x x x x x x
Ventricular fibrillation def Ventricular fibrillation def x x
Ventricular tachycardia def Ventricular tachycardia def x x x x x x
Sustained ventricular tachycardia def x
Viral infection def Viral infection def x x x x x x
Visual impairment def Visual impairment def x x x x x x x
Visual acuity reduced Visual impairment def x x x x x x x
Blindness def Visual impairment def x x x x x x x
Weight increased def Weight increased def x x x x x x x
Weight decreased def Weight decreased def x x x x x x x
Wheezing def Wheezing def x x x x x x x
Chills def Chills def x x x x x x
Orthopnoea Orthopnoea x x x x x x x x x
Photophobia def Photophobia def x x x x x x x
Oedema peripheral def Oedema peripheral def x x x x x
Depressive symptom Depressive symptom x x
Hepatic function abnormal Hepatic function abnormal
Antinuclear antibody positive def Antinuclear antibody positive def x x x x x x
Atrioventricular block complete def Atrioventricular block complete def x
Blood creatinine increased Creatinine increased def x x x
Serum creatinine increased x
Generalised oedema Generalised oedema x x x x x x
Fluid retention Generalised oedema x x x x x x
Red blood cell sedimentation rate increased Red blood cell sedimentation rate increased x x x x x
Ventricular extrasystoles def Ventricular extrasystoles def x x x x x
Papillary muscle rupture Papillary muscle rupture x
Breath sounds abnormal Abnormal chest sounds NOS x x x x x x
Pseudolymphoma def Pseudolymphoma def x x x
Lymphocytoma cutis x x x
Malaise def Malaise def x x x x x x x x
Discomfort def Malaise def x x x x x x x x
Discomfort def x x x x x x
Ill-defined disorder Malaise def x x x x x x x x
Myalgia def Myalgia def x x x x x x
Cardiac fibrillation Cardiac fibrillation x x x x x x x
Memory impairment def Memory impairment def x x x x x x x
Chest discomfort Chest discomfort x x x x x x
Lung infiltration Lung infiltration x x x x x x x
Anaphylactic shock def Anaphylactoid reaction x x x x x x
Anaphylactoid reaction Anaphylactoid reaction x x x x x x
Vision blurred def Vision blurred def x x x x x x x x
Nocturnal dyspnoea Nocturnal dyspnoea x x x x
Photosensitivity reaction def Photosensitivity def x x x x x x x
Dysaesthesia def Dysaesthesia def x x x x x x x
Painful respiration Painful respiration x x x x x x x
Bradycardia def Bradycardia def x x x x x
Fluid overload def Fluid overload def x x x x x x
Atrial tachycardia def Atrial tachycardia def x x x x x
Drug interaction def Drug interaction def x x x x
Aortic dissection def Dissecting aortic aneurysm, thoracic
Hypersomnia def Hypersomnia def x x x x x x x
Insomnia def Insomnia def x x x x x x x x x
Rhinorrhoea def Rhinorrhoea def x x x x x x x
Death Death
Dyspnoea paroxysmal nocturnal Dyspnoea paroxysmal nocturnal x x x x
Somnolence def Somnolence def x x x x x x x x x
Indication Labels
Acute myocardial infarction x x x x x x x x x
Adjuvant therapy def x x x
Agranulocytosis def x x x x x x
Angioedema def x x x x x x x x x
Angiopathy def x x x x x x
Cardiac failure def x x x x x x x x x
Cardiac failure congestive def x x x
Collagen-vascular disease x x x x
Elderly def x
Essential hypertension def x x x
Hypertension def x x x x x x x x x
Hypotension def x x x
Infarction def x x x x x x x x x
Left ventricular dysfunction def x x x
Myocardial infarction def x x x x x x x x x
Renal failure def x x x
Renal impairment def x x x x x x x x x
Renal vessel disorder x x x
Renovascular hypertension def x x x
Sexually transmitted disease def x
Ventricular dysfunction def x x x

Information

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: C09AA03

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. LISINOPRIL / RATIO-LISINOPRIL P : 6 side effects (Health Canada)
  2. LISINOPRIL / PRINIVIL : 40 side effects (Health Canada)
  3. LISINOPRIL (LISINOPRIL DIHYDRATE) / CO LISINOPRIL : 54 side effects (Health Canada)
  4. lisinopril / Zestril : 82 side effects (FDA MedWatch)
  5. LISINOPRIL : 127 side effects (FDA XML label)
  6. lisinopril / Prinivil : 154 side effects (FDA MedWatch)
  7. lisinopril / Zestril : 162 side effects (FDA MedWatch)
  8. LISINOPRIL : 163 side effects (FDA XML label)
  9. LISINOPRIL : 165 side effects (FDA XML label)
  10. LISINOPRIL : 169 side effects (FDA XML label)