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Medroxyprogesterone acetate

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Codes: None found

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11
Nervousness postmarketing, 12% x x x x x x x x x x x
Abdominal distress 12% x
Headache 8% - 17% x x x x x x x x x x x
Metrorrhagia 7% x x x x x x
Amenorrhoea 6% x x x x x x x x x x
Libido decreased 6% x x x x x x
Dizziness 6% x x x x x x x x x x x
Weight increased 6% - 7% x x x x x
Asthenia postmarketing, 5% x x x x x x
Injection site reaction 5% x x x x x x
Nausea 4% x x x x x x x x x x x
Pain in extremity 4% x x x x
Arthralgia postmarketing, 1-5% x x x x x x
Leukorrhea 1-5% x x x
Pelvic pain 1-5% x x x
Vaginal inflammation 1-5% x x x x x x
Anorgasmia 1-5% x x x
Vaginal discharge 3% x
Tenderness 3% x x x x x x x
Back pain 2% x x x x x x
Depression 2% x x x x x x x
Dysmenorrhoea 2% x x x x x x
Oedema peripheral 2% x x x
Abdominal bloating 2% x x x x x x
Rash 1% x x x x x
Pruritus vulvae 1% x
Hot flush 1% x x x
Infection postmarketing, 0.2 - 1.0% x x x x x x
Constipation 0.2 - 1.0% x x x x x
Dyspnoea postmarketing, 0.2 - 1.0% x x x x x x
Hypersensitivity postmarketing, 0.2 - 1.0% x x x x x x x x x
Pruritus postmarketing, 0.2 - 1% x x x x x x x x x x x
Tachycardia postmarketing, 0.2 - 1.0% x x x x x x x x
Pollakiuria 0.2 - 1.0% x
Urticaria postmarketing, 0.2 - 1.0% x x x x x x x x x x x
Insomnia 0.2 - 1.0% x x x x x x x x x x x
Ocular discomfort 0.2 - 1.0% x x
Dyspareunia 0.2 - 1.0% x x x x x x
Anaphylactic shock postmarketing x x x x x x x x x x x
Anaemia postmarketing x x x x x x
Angioedema postmarketing x x x x x x x x x x x
Anovulation postmarketing x x x x x x x
Asthma postmarketing x x x x x x
Breast cancer postmarketing x x x x x x
Chest pain postmarketing x x x x x x
Scleroderma postmarketing x x x x x x
Facial paralysis postmarketing x x x x x x
Body temperature increased postmarketing x x x x x x x x x x
Blood disorder postmarketing x x x x x x
Haemorrhage postmarketing x x x x x x x
Hoarseness postmarketing x x x x x x
Hyperplasia postmarketing x x x x x x
Libido increased postmarketing x x x x x x
Jaundice postmarketing x x x x x x x x x
Breast mass postmarketing x x x x x x
Chloasma postmarketing x x x x x x x x x
Oligomenorrhoea postmarketing x x x
Osteoporosis postmarketing x x x x x x
Paraesthesia postmarketing x x x x x x
Pulmonary embolism postmarketing x x x x x x x x x x
Convulsion postmarketing x x x x x x
Swelling postmarketing x x x x x x x
Syncope postmarketing x x x x x x
Thrombophlebitis postmarketing x x x x x x x x x x x
Unintended pregnancy postmarketing x x x x
Chills postmarketing x x x x x x
Body odor postmarketing x x x x x x
Breast discharge postmarketing x x x
Deep vein thrombosis postmarketing x x x x x x
Glucose tolerance decreased postmarketing x x x x x x x x x x
Dry skin postmarketing x x x x x x
Digestion impaired postmarketing x x x x x x
Galactorrhoea postmarketing x x x x x x x x x x
Vaginal cyst postmarketing x x x x x x
Rectal haemorrhage postmarketing x x x x x x
Cervix carcinoma postmarketing x x x x x x
Anaphylactoid reaction postmarketing x x x x x x
Osteoporotic fracture postmarketing x x x x x x
Paralysis postmarketing x x x x x x
Excessive thirst postmarketing x x x x x x
Somnolence postmarketing x x x x x x x x x x x
Abdominal distension x x
Abdominal pain x x x x x
Congenital anomaly x
Abortion spontaneous x
Abortion missed x
Abscess x x x
Pancreatitis acute x
Alopecia x x x x x x x
Amnesia x
Haemolytic anaemia x
Anencephaly x
Anorexia x
Anosmia x
Anxiety x x x
Ataxia x
Mental disorder x x x
Clotting x
Bone disorder x x x
Breast disorder x x x
Breast feeding x x
Breast swelling x x x x
Bronchospasm x
Bronchitis x x x
Cachexia x
Neoplasm malignant x x
Vaginal moniliasis x x x
Squamous cell carcinoma x
Transient ischaemic attack x
Cervical dysplasia x
Uterine cervical erosion x x x
Cholangitis x
Cholelithiasis x
Cleft palate x
Confusional state x x x x
Connective tissue disorder x
Coronary artery thrombosis x x x
Cushing's syndrome x
Cystitis x x x
Cyst x
Dysphagia x
Diabetes mellitus x x x x
Cataract diabetic x x x x
Diarrhoea x x x x x x x
Trisomy 21 x
Drowsiness x x x
Dysarthria x
Dysgeusia x
Dysuria x x x x
Eating disorder x
Oedema x x x x x x x x
Embolism x
Endocrine disorder x
Epistaxis x
Erythema multiforme x x x
Erythema nodosum x x x
Oesophageal atresia x
Eye disorder x
Fatigue x x x x x x x x x x x
Microsomia x
Fibrocystic breast disease x
Gallbladder disorder x x x x
Gastrointestinal disorder x x x
Glycosuria x x x x
Heart malformation x
Cardiac disorder x x x
Cardiac failure congestive x x x x
Heartburn x
Haemorrhagic disorder x
Hepatitis x
Hepatomegaly x
Congenital megacolon x
Hirsutism x x x x x x x x
Hodgkin's disease x
Polyhydramnios x
Hydrocephalus x
Hydrops foetalis x
Hypercalcaemia x x x x
Hyperglycaemia x x x
Hyperkalaemia x
Hypernatraemia x x x x
Hyperthyroidism x
Salivary gland enlargement x
Hypoglycaemia x
Hypokalaemia x
Hypopituitarism x
Hypotension x
Orthostatic hypotension x
Hypothyroidism x
Immune system disorder x x x
Infarction x
Influenza x x x
Irritability x x x x x x x
Jaundice cholestatic x x x x x
Renal neoplasm x
Laryngeal oedema x
Laryngospasm x
Cramps of lower extremities x x x
Leg pain x x x
Leukocytosis x
Liver disorder x
Breast pain x x x x x x x
Mediastinal disorder x
Malignant melanoma x
Meningioma x
Premature menopause x
Menorrhagia x x x x
Microcephaly x
Cramp muscle x x x x x x
Musculoskeletal pain x x
Myocardial infarction x x x x x
Myoclonus x
Nasopharyngitis x x x
Necrosis x
Neoplasm x x x
Nephritis interstitial x
Nephrotic syndrome x
Nervous system disorder x x x
Neuritis x x x
Neurofibroma x
IIIrd nerve paralysis x
Optic neuritis x x x x
Osteonecrosis x
Ovarian cyst x
Palpitations x x x x x x x x
Papilloedema x
Pericarditis x
Pharyngitis x x x
Polyp x
Pregnancy x
Ectopic pregnancy x
Premenstrual syndrome x x x
Proteinuria x
Benign intracranial hypertension x
Henoch-Schonlein purpura x
Thrombotic thrombocytopenic purpura x
Renal infarct x
Acute respiratory distress syndrome x
Retinal vein occlusion x
Salpingitis x
Sinusitis x x x
Skin disorder x x
Speech disorder x
Splenic infarction x
Cerebrovascular accident x
Sudden infant death syndrome x
Sweating x x x x
Supraventricular tachycardia x
Thrombocytopenia x
Thromboembolism x x x x x
Thrombosis x x x x x x x
Thyroiditis x
Tinnitus x
Tracheo-oesophageal fistula x
Tremor x x x
Turner's syndrome x
Ulcer x
Attention deficit disorder x
Erythema x
Upper respiratory tract infection x x x
Urinary tract infection x x x
Urinary tract disorder x
Uterine disorder x
Uterine leiomyoma x
Vaginal itching x x x
Varicose vein x x x x x x
Angiopathy x x x
Venous thrombosis x
Vertigo x x
Disorder sight x x x x
Vomiting x x x x x x x
Weight decreased x
Dry mouth x x x x
Spina bifida x
Urinary retention x
Vaginitis bacterial x x x
Hepatic failure x
Agitation x
Mood swings x
Acute leukaemia x
Hepatic function abnormal x x x
Mouth ulceration x
Migraine x x x x
Injection site atrophy x
Muscular weakness x
Injection site pain x x x x x x
Phosphatase alkaline increased x
Electrocardiogram QT prolonged x
Alanine aminotransferase increased x
Arterial thrombosis x
Cerebral venous thrombosis x
Joint swelling x
Polydactyly x
Optic ischaemic neuropathy x
Vaginal dysplasia x
Menstruation irregular x x x x x x x
Malnutrition x
Porphyria acute x
Unspecified disorder of skin and subcutaneous tissue x
Fibroadenoma of breast x
Fatal outcomes x
Malaise x x x x x
Immobile x x
Myalgia x
Increased appetite x
Abdominal discomfort x x x x
Abdominal pain lower x
Menometrorrhagia x x x
Discomfort x x
Euphoric mood x x x
Blood creatinine increased x
Congenital diaphragmatic hernia x
Skull malformation x
Dermatitis hemorrhagic x x x
Sickle cell anaemia with crisis x
Oestrogen low x
Limb deformity x
Tremor of hands x x x
Sexually active x x
Testosterone low x
Intestinal infarction x
Parkinsonism x
Sepsis x
Breast tenderness x x x x
Vulval abscess x
Ear malformation x
Blighted ovum x
Hepatobiliary disease x x x
Fluid retention x x x
Uterine cyst x
Antepartum hemorrhage x
Macular oedema x
Acute psychosis x
Benign breast neoplasm x
Nephrolithiasis x
Hyperpyrexia x x
Progesterone levels x
Bradycardia x
Smear cervix abnormal x
Blood pressure increased x x x x x x x
Rash generalised x x x
Face oedema x
Visual disturbance x x x
Benign hydatidiform mole x
Dysfunction adrenal x
Balance disorder x
Mass x
Stillbirth x
Drug interaction x
Sweating increased x x
Acne x x x x x x x
Memory loss x
Infestation NOS x
Blood and lymphatic system disorders x x x
Ear and labyrinth disorders x
Oestrogen deficiency x
Oropharyngeal swelling x
Oral mucosal blistering x
Genital haemorrhage x
Porphyria aggravated x
Thromboembolic event x x
Vaginal mucosal blistering x
Cerebral ischaemia x
Anaphylactic responses x x
Dysphemia x
Ovarian cancer x
Attention deficit/hyperactivity disorder x
Talipes x
Single umbilical artery x
Paranoia x
Cerebral haemorrhage x
Vaginal haemorrhage x x x
Bleeding breakthrough x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

MEDROXYPROGESTERONE ACETATE / DOM-MEDROXYPROGESTERONE

Side effects:58
Source:Health Canada

MEDROXYPROGESTERONE ACETATE / APO-MEDROXY

Side effects:63
Source:Health Canada

MEDROXYPROGESTERONE ACETATE / GEN-MEDROXY TABLET 5MG

Side effects:66
Source:Health Canada

Medroxyprogesterone acetate / Provera, Tablet

Side effects:51
Source:Medsafe

Injection Suspension / DEPO-RALOVERA

Side effects:104
Source:medicines.org.au

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label