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Definition: A localized or systemic chronic and progressive autoimmune disorder characterized by thickening of the skin and the connective tissues. Localized scleroderma affects only the skin. Systemic scleroderma also affects internal organs, including the heart, lungs, gastrointestinal tract, and kidneys.

Synonyms (terms occurring on more labels are shown first): scleroderma

More information: PubMed search and possibly Wikipedia

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