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Medroxyprogesterone acetate

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Codes: None found

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11
Nervousness Nervousness postmarketing, 12% x x x x x x x x x x x
Tension Nervousness postmarketing, 12% x x x x x x x x x x x
Abdominal discomfort Abdominal distress 12% x
Abdominal discomfort x x x x
Headache Headache 8% - 17% x x x x x x x x x x x
Metrorrhagia Metrorrhagia 7% x x x x x x
Bleeding breakthrough x x x
Amenorrhoea Amenorrhoea 6% x x x x x x x x x x
Libido decreased Libido decreased 6% x x x x x x
Disturbance in sexual arousal Libido decreased 6% x x x x x x
Libido increased postmarketing x x x x x x
Dizziness Dizziness 6% x x x x x x x x x x x
Syncope postmarketing x x x x x x
Weight increased Weight increased 6% - 7% x x x x x
Asthenia Asthenia postmarketing, 5% x x x x x x
Fatigue x x x x x x x x x x x
Injection site reaction Injection site reaction 5% x x x x x x
Nausea Nausea 4% x x x x x x x x x x x
Pain in extremity Pain in extremity 4% x x x x
Leg pain x x x
Arthralgia Arthralgia postmarketing, 1-5% x x x x x x
Musculoskeletal discomfort Arthralgia postmarketing, 1-5% x x x x x x
Myalgia x
Vaginal discharge Leukorrhea 1-5% x x x
Vaginal discharge 3% x
Pelvic pain Pelvic pain 1-5% x x x
Vaginal inflammation Vaginal inflammation 1-5% x x x x x x
Vaginal infection Vaginal inflammation 1-5% x x x x x x
Vaginitis bacterial x x x
Anorgasmia Anorgasmia 1-5% x x x
Tenderness Tenderness 3% x x x x x x x
Back pain Back pain 2% x x x x x x
Depression Depression 2% x x x x x x x
Dysmenorrhoea Dysmenorrhoea 2% x x x x x x
Oedema peripheral Oedema peripheral 2% x x x
Abdominal distension Abdominal bloating 2% x x x x x x
Abdominal distension x x
Flatulence Abdominal bloating 2% x x x x x x
Dermatitis Rash 1% x x x x x
Rash Rash 1% x x x x x
Vulvovaginal pruritus Pruritus vulvae 1% x
Vaginal itching x x x
Menopausal symptoms Hot flush 1% x x x
Hot flush Hot flush 1% x x x
Infection Infection postmarketing, 0.2 - 1.0% x x x x x x
Constipation Constipation 0.2 - 1.0% x x x x x
Dyspnoea Dyspnoea postmarketing, 0.2 - 1.0% x x x x x x
Hypersensitivity Hypersensitivity postmarketing, 0.2 - 1.0% x x x x x x x x x
Pruritus Pruritus postmarketing, 0.2 - 1% x x x x x x x x x x x
Tachycardia Tachycardia postmarketing, 0.2 - 1.0% x x x x x x x x
Pollakiuria Pollakiuria 0.2 - 1.0% x
Urticaria Urticaria postmarketing, 0.2 - 1.0% x x x x x x x x x x x
Insomnia Insomnia 0.2 - 1.0% x x x x x x x x x x x
Ocular discomfort Ocular discomfort 0.2 - 1.0% x x
Dyspareunia Dyspareunia 0.2 - 1.0% x x x x x x
Anaphylactic shock Anaphylactic shock postmarketing x x x x x x x x x x x
Anaphylactoid reaction postmarketing x x x x x x
Anaemia Anaemia postmarketing x x x x x x
Angioedema Angioedema postmarketing x x x x x x x x x x x
Anovulatory cycle Anovulation postmarketing x x x x x x x
Asthma Asthma postmarketing x x x x x x
Breast cancer Breast cancer postmarketing x x x x x x
Chest pain Chest pain postmarketing x x x x x x
Scleroderma Scleroderma postmarketing x x x x x x
VIIth nerve paralysis Facial paralysis postmarketing x x x x x x
Body temperature increased Body temperature increased postmarketing x x x x x x x x x x
Blood disorder Blood disorder postmarketing x x x x x x
Haemorrhage Haemorrhage postmarketing x x x x x x x
Haemoglobin Haemorrhage postmarketing x x x x x x x
Dysphonia Hoarseness postmarketing x x x x x x
Hyperplasia Hyperplasia postmarketing x x x x x x
Libido increased Libido increased postmarketing x x x x x x
Jaundice Jaundice postmarketing x x x x x x x x x
Breast mass Breast mass postmarketing x x x x x x
Chloasma Chloasma postmarketing x x x x x x x x x
Oligomenorrhoea Oligomenorrhoea postmarketing x x x
Osteoporosis Osteoporosis postmarketing x x x x x x
Paraesthesia Paraesthesia postmarketing x x x x x x
Pulmonary embolism Pulmonary embolism postmarketing x x x x x x x x x x
Convulsion Convulsion postmarketing x x x x x x
Swelling Swelling postmarketing x x x x x x x
Shock Syncope postmarketing x x x x x x
Syncope Syncope postmarketing x x x x x x
Loss of consciousness Syncope postmarketing x x x x x x
Thrombophlebitis Thrombophlebitis postmarketing x x x x x x x x x x x
Unintended pregnancy Unintended pregnancy postmarketing x x x x
Chills Chills postmarketing x x x x x x
Skin odour abnormal Body odor postmarketing x x x x x x
Breast discharge Breast discharge postmarketing x x x
Deep vein thrombosis Deep vein thrombosis postmarketing x x x x x x
Glucose tolerance decreased Glucose tolerance decreased postmarketing x x x x x x x x x x
Dry skin Dry skin postmarketing x x x x x x
Dyspepsia Digestion impaired postmarketing x x x x x x
Heartburn x
Gastrointestinal disorder Digestion impaired postmarketing x x x x x x
Gastrointestinal disorder x x x
Galactorrhoea Galactorrhoea postmarketing x x x x x x x x x x
Vaginal cyst Vaginal cyst postmarketing x x x x x x
Rectal haemorrhage Rectal haemorrhage postmarketing x x x x x x
Cervix carcinoma Cervix carcinoma postmarketing x x x x x x
Anaphylactoid reaction Anaphylactoid reaction postmarketing x x x x x x
Osteoporotic fracture Osteoporotic fracture postmarketing x x x x x x
Paralysis Paralysis postmarketing x x x x x x
Thirst Excessive thirst postmarketing x x x x x x
Somnolence Somnolence postmarketing x x x x x x x x x x x
Drowsiness x x x
Abdominal pain Abdominal pain x x x x x
Gastrointestinal pain Abdominal pain x x x x x
Congenital anomaly Congenital anomaly x
Developmental delay Congenital anomaly x
Abortion spontaneous Abortion spontaneous x
Abortion missed Abortion missed x
Abscess Abscess x x x
Pancreatitis acute Pancreatitis acute x
Alopecia Alopecia x x x x x x x
Amnesia Amnesia x
Memory loss x
Haemolytic anaemia Haemolytic anaemia x
Anencephaly Anencephaly x
Decreased appetite Anorexia x
Anosmia Anosmia x
Anxiety Anxiety x x x
Ataxia Ataxia x
Mental disorder Mental disorder x x x
Coagulopathy Clotting x
Bone disorder Bone disorder x x x
Breast disorder Breast disorder x x x
Breast feeding Breast feeding x x
Breast swelling Breast swelling x x x x
Bronchospasm Bronchospasm x
Bronchitis Bronchitis x x x
Cachexia Cachexia x
Neoplasm malignant Neoplasm malignant x x
Vulvovaginal candidiasis Vaginal moniliasis x x x
Vulvovaginal mycotic infection Vaginal moniliasis x x x
Squamous cell carcinoma Squamous cell carcinoma x
Transient ischaemic attack Transient ischaemic attack x
Cervical dysplasia Cervical dysplasia x
Uterine cervical erosion Uterine cervical erosion x x x
Cholangitis Cholangitis x
Cholelithiasis Cholelithiasis x
Cleft palate Cleft palate x
Confusional state Confusional state x x x x
Feeling abnormal Confusional state x x x x
Malaise x x x x x
Connective tissue disorder Connective tissue disorder x
Coronary artery thrombosis Coronary artery thrombosis x x x
Cushing's syndrome Cushing's syndrome x
Cystitis Cystitis x x x
Bladder pain Cystitis x x x
Cystitis noninfective Cystitis x x x
Cyst Cyst x
Dysphagia Dysphagia x
Diabetes mellitus Diabetes mellitus x x x x
Cataract diabetic Cataract diabetic x x x x
Diarrhoea Diarrhoea x x x x x x x
Trisomy 21 Trisomy 21 x
Dysarthria Dysarthria x
Osteoarthritis Dysarthria x
Dysgeusia Dysgeusia x
Dysuria Dysuria x x x x
Eating disorder Eating disorder x
Oedema Oedema x x x x x x x x
Embolism Embolism x
Thromboembolism x x x x x
Thromboembolic event x x
Endocrine disorder Endocrine disorder x
Epistaxis Epistaxis x
Erythema multiforme Erythema multiforme x x x
Erythema nodosum Erythema nodosum x x x
Oesophageal atresia Oesophageal atresia x
Eye disorder Eye disorder x
Fatigue Fatigue x x x x x x x x x x x
Microsomia Microsomia x
Fibrocystic breast disease Fibrocystic breast disease x
Gallbladder disorder Gallbladder disorder x x x x
Glycosuria Glycosuria x x x x
Heart disease congenital Heart malformation x
Cardiac disorder Cardiac disorder x x x
Cardiac failure congestive Cardiac failure congestive x x x x
Haemorrhagic disorder Haemorrhagic disorder x
Hepatitis Hepatitis x
Hepatomegaly Hepatomegaly x
Congenital megacolon Congenital megacolon x
Hirsutism Hirsutism x x x x x x x x
Hodgkin's disease Hodgkin's disease x
Hodgkin's disease lymphocyte depletion type stage unspecified Hodgkin's disease x
Hodgkin's disease lymphocyte predominance type stage unspecified Hodgkin's disease x
Polyhydramnios Polyhydramnios x
Hydrocephalus Hydrocephalus x
Hydrops foetalis Hydrops foetalis x
Hypercalcaemia Hypercalcaemia x x x x
Hyperglycaemia Hyperglycaemia x x x
Hyperkalaemia Hyperkalaemia x
Hypernatraemia Hypernatraemia x x x x
Hyperthyroidism Hyperthyroidism x
Salivary gland enlargement Salivary gland enlargement x
Hypoglycaemia Hypoglycaemia x
Hypokalaemia Hypokalaemia x
Hypopituitarism Hypopituitarism x
Hypotension Hypotension x
Orthostatic hypotension Orthostatic hypotension x
Hypothyroidism Hypothyroidism x
Immune system disorder Immune system disorder x x x
Infarction Infarction x
Influenza Influenza x x x
Irritability Irritability x x x x x x x
Jaundice cholestatic Jaundice cholestatic x x x x x
Renal neoplasm Renal neoplasm x
Laryngeal oedema Laryngeal oedema x
Laryngospasm Laryngospasm x
Muscle spasms Cramps of lower extremities x x x
Cramp muscle x x x x x x
Leukocytosis Leukocytosis x
Liver disorder Liver disorder x
Hepatocellular injury Liver disorder x
Foetor hepaticus Liver disorder x
Breast pain Breast pain x x x x x x x
Mediastinal disorder Mediastinal disorder x
Malignant melanoma Malignant melanoma x
Meningioma Meningioma x
Premature menopause Premature menopause x
Menorrhagia Menorrhagia x x x x
Microcephaly Microcephaly x
Musculoskeletal pain Musculoskeletal pain x x
Myocardial infarction Myocardial infarction x x x x x
Acute coronary syndrome Myocardial infarction x x x x x
Myoclonus Myoclonus x
Nasopharyngitis Nasopharyngitis x x x
Necrosis Necrosis x
Neoplasm Neoplasm x x x
Tubulointerstitial nephritis Nephritis interstitial x
Nephrotic syndrome Nephrotic syndrome x
Nervous system disorder Nervous system disorder x x x
Neuritis Neuritis x x x
Neuropathy peripheral Neuritis x x x
Neurofibroma Neurofibroma x
IIIrd nerve paralysis IIIrd nerve paralysis x
Optic neuritis Optic neuritis x x x x
Papilloedema x
Osteonecrosis Osteonecrosis x
Ovarian cyst Ovarian cyst x
Palpitations Palpitations x x x x x x x x
Papilloedema Papilloedema x
Pericarditis Pericarditis x
Pharyngitis Pharyngitis x x x
Polyp Polyp x
Pregnancy Pregnancy x
Ectopic pregnancy Ectopic pregnancy x
Premenstrual syndrome Premenstrual syndrome x x x
Proteinuria Proteinuria x
Protein urine present Proteinuria x
Benign intracranial hypertension Benign intracranial hypertension x
Henoch-Schonlein purpura Henoch-Schonlein purpura x
Thrombotic thrombocytopenic purpura Thrombotic thrombocytopenic purpura x
Renal infarct Renal infarct x
Acute respiratory distress syndrome Acute respiratory distress syndrome x
Retinal vein occlusion Retinal vein occlusion x
Salpingitis Salpingitis x
Sinusitis Sinusitis x x x
Skin disorder Skin disorder x x
Unspecified disorder of skin and subcutaneous tissue x
Speech disorder Speech disorder x
Splenic infarction Splenic infarction x
Cerebrovascular accident Cerebrovascular accident x
Sudden infant death syndrome Sudden infant death syndrome x
Hyperhidrosis Sweating x x x x
Sweating increased x x
Supraventricular tachycardia Supraventricular tachycardia x
Thrombocytopenia Thrombocytopenia x
Embolism venous Thromboembolism x x x x x
Thrombosis Thrombosis x x x x x x x
Thyroiditis Thyroiditis x
Tinnitus Tinnitus x
Tracheo-oesophageal fistula Tracheo-oesophageal fistula x
Tremor Tremor x x x
Tremor of hands x x x
Turner's syndrome Turner's syndrome x
Ulcer Ulcer x
Attention deficit/hyperactivity disorder Attention deficit disorder x
Attention deficit/hyperactivity disorder x
Erythema Erythema x
Upper respiratory tract infection Upper respiratory tract infection x x x
Urinary tract infection Urinary tract infection x x x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Uterine disorder Uterine disorder x
Uterine leiomyoma Uterine leiomyoma x
Varicose vein Varicose vein x x x x x x
Angiopathy Angiopathy x x x
Venous thrombosis Venous thrombosis x
Vertigo Vertigo x x
Visual impairment Disorder sight x x x x
Visual disturbance x x x
Vomiting Vomiting x x x x x x x
Weight decreased Weight decreased x
Dry mouth Dry mouth x x x x
Spina bifida Spina bifida x
Urinary retention Urinary retention x
Vaginitis bacterial Vaginitis bacterial x x x
Hepatic failure Hepatic failure x
Agitation Agitation x
Mood swings Mood swings x
Affect lability Mood swings x
Acute leukaemia Acute leukaemia x
Hepatic function abnormal Hepatic function abnormal x x x
Stomatitis Mouth ulceration x
Mouth ulceration Mouth ulceration x
Migraine Migraine x x x x
Injection site atrophy Injection site atrophy x
Muscular weakness Muscular weakness x
Injection site pain Injection site pain x x x x x x
Blood alkaline phosphatase increased Phosphatase alkaline increased x
Electrocardiogram QT prolonged Electrocardiogram QT prolonged x
Alanine aminotransferase increased Alanine aminotransferase increased x
Arterial thrombosis Arterial thrombosis x
Cerebral venous thrombosis Cerebral venous thrombosis x
Joint swelling Joint swelling x
Polydactyly Polydactyly x
Optic ischaemic neuropathy Optic ischaemic neuropathy x
Vaginal dysplasia Vaginal dysplasia x
Menstruation irregular Menstruation irregular x x x x x x x
Malnutrition Malnutrition x
Porphyria acute Porphyria acute x
Fibroadenoma of breast Fibroadenoma of breast x
Malaise Malaise x x x x x
Discomfort Malaise x x x x x
Discomfort x x
Ill-defined disorder Malaise x x x x x
Immobile Immobile x x
Myalgia Myalgia x
Increased appetite Increased appetite x
Abdominal pain lower Abdominal pain lower x
Menometrorrhagia Menometrorrhagia x x x
Euphoric mood Euphoric mood x x x
Blood creatinine increased Blood creatinine increased x
Congenital diaphragmatic hernia Congenital diaphragmatic hernia x
Skull malformation Skull malformation x
Purpura Dermatitis hemorrhagic x x x
Sickle cell anaemia with crisis Sickle cell anaemia with crisis x
Blood oestrogen decreased Oestrogen low x
Limb deformity Limb deformity x
Sexually active Sexually active x x
Blood testosterone decreased Testosterone low x
Intestinal infarction Intestinal infarction x
Parkinsonism Parkinsonism x
Sepsis Sepsis x
Breast tenderness Breast tenderness x x x x
Vulval abscess Vulval abscess x
Ear malformation Ear malformation x
Blighted ovum Blighted ovum x
Hepatobiliary disease Hepatobiliary disease x x x
Fluid retention Fluid retention x x x
Uterine cyst Uterine cyst x
Haemorrhage in pregnancy Antepartum hemorrhage x
Macular oedema Macular oedema x
Acute psychosis Acute psychosis x
Benign breast neoplasm Benign breast neoplasm x
Nephrolithiasis Nephrolithiasis x
Hyperpyrexia Hyperpyrexia x x
Progesterone Progesterone levels x
Bradycardia Bradycardia x
Smear cervix abnormal Smear cervix abnormal x
Blood pressure increased Blood pressure increased x x x x x x x
Rash generalised Rash generalised x x x
Face oedema Face oedema x
Benign hydatidiform mole Benign hydatidiform mole x
Adrenal disorder Dysfunction adrenal x
Balance disorder Balance disorder x
Mass Mass x
Stillbirth Stillbirth x
Drug interaction Drug interaction x
Acne Acne x x x x x x x
Infestation Infestation NOS x
Oestrogen deficiency Oestrogen deficiency x
Oropharyngeal swelling Oropharyngeal swelling x
Oral mucosal blistering Oral mucosal blistering x
Genital haemorrhage Genital haemorrhage x
Porphyrin metabolism disorder Porphyria aggravated x
Vaginal mucosal blistering Vaginal mucosal blistering x
Cerebral ischaemia Cerebral ischaemia x
Dysphemia Dysphemia x
Ovarian cancer Ovarian cancer x
Talipes Talipes x
Single umbilical artery Single umbilical artery x
Psychotic disorder Paranoia x
Paranoia Paranoia x
Cerebral haemorrhage Cerebral haemorrhage x
Vaginal haemorrhage Vaginal haemorrhage x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

MEDROXYPROGESTERONE ACETATE / DOM-MEDROXYPROGESTERONE

Side effects:58
Source:Health Canada

MEDROXYPROGESTERONE ACETATE / APO-MEDROXY

Side effects:63
Source:Health Canada

MEDROXYPROGESTERONE ACETATE / GEN-MEDROXY TABLET 5MG

Side effects:66
Source:Health Canada

Medroxyprogesterone acetate / Provera, Tablet

Side effects:51
Source:Medsafe

Injection Suspension / DEPO-RALOVERA

Side effects:104
Source:medicines.org.au

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label