Alkeran

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4
Aggression def x
Alopecia def x x x x
Amenorrhoea def x
Anaphylactic shock def x x x x
Anaemia def x x x x
Haemolytic anaemia def x x x x
Anorexia def x
Arrhythmia def x
Atrial fibrillation def x
Bronchospasm def x x
Chest pain def x
Compartment syndrome def x
Cough def x
Cystitis def x
Dermatitis def x
Diarrhoea def x x x x
Dyspnoea def x x
Oedema def x x
Rash def x x
Extravasation def x
Fatigue def x
Fibrosis def x x x x
Flushing def x x
Cardiac arrest def x x
Haemorrhage def x
Hepatitis def x x x
Hypersensitivity def x x x x
Hyponatraemia def x
Hypotension def x x
Immunosuppression def x
Infection def x x
Infertility def x
Jaundice def x x x
Renal failure acute def x
Leukaemia def x
Leukopenia def x x
Liver disorder def x x x
Lymphoma def x
Muscle atrophy def x
Nausea def x x x x
Necrosis def x x
Neoplasm def x
Neutropenia def x x
Obstruction def x
Pain def x x
Pancreatic disorder def x
Pancytopenia def x x x x
Pneumonia def x x x x
Pruritus def x x
Pulmonary fibrosis def x x x x
Rales x
Renal failure def x
Rhabdomyolysis def x
Seizures def x
Skin ulcer def x
Spinal cord disorder def x
Stomatitis def x x
Tachycardia def x x
Thrombocytopenia def x x
Thrombosis def x
Ulcer def x x x x
Ureteric obstruction def x
Uric acid level increased x
Urticaria def x x
Vasculitis def x x x x
Vomiting def x x x x
Acute leukaemia def x
Hepatic function abnormal x x x x
Mouth ulceration def x x
Impaired healing x
Injection site reaction def x
Liver function test abnormal x x x x
Skin necrosis x
Arterial thrombosis x
Interstitial pneumonia x x x
Myalgia def x
Cardiac fibrillation x
Muscle necrosis def x
Hypoxia def x
Atrophy def x
Muscle damage x
Withdrawn x x
Transaminases increased x
Neuropathy def x
Respiratory distress def x
Sensation of warmth x x
Cutaneous hypersensitivity def x x x
Sterility def x
Serum creatinine increased x
Hyperuricaemia def x
Febrile neutropenia def x
Second primary malignancy def x
Local reaction x
Myelosuppression def x x
Muscle fibrosis x
Pulmonary toxicity x
Cytolysis def x
Insufficiency renal def x
Tingling sensation def x x
Bladder irritation x
Indication Labels
Body temperature increased def x x
Breast cancer def x
Carcinoma def x x x
Malignant melanoma def x x
Multiple myeloma def x x x x
Neoplasm malignant def x
Neuroblastoma def x
Ovarian cancer def x
Ovarian disorder def x x x
Ovarian epithelial cancer def x x x
Rhabdomyosarcoma def x
Waldenstrom's macroglobulinaemia def x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: L01AA03

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. MELPHALAN / ALKERAN : 21 side effects (Drugs@FDA)
  2. melphalan / Alkeran : 23 side effects (FDA MedWatch)
  3. MELPHALAN / ALKERAN : 56 side effects (Health Canada)
  4. Melphalan : 80 side effects (BC Cancer)