Search results :

Melphalan

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: L01AA03

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Injection site reaction 50% x
Anaemia very common x x x x x x
Leukopenia very common x x x x x x
Muscle atrophy very common x x
Nausea very common x x x x x x x
Thrombocytopenia very common x x x x x x
Bone marrow depression very common x x
Myalgia very common x x
Sensation of warmth very common x x x x
Blood creatine phosphokinase increased very common x
Muscle fibrosis very common x x
Tingling sensation very common x x x x
Alopecia common, very common x x x x x x x
Diarrhoea rare, very common x x x x x x
Vomiting rare, very common x x x x x x x
Compartment syndrome common x x
Plasma cell myeloma common x
Neuropathy 2% x
Anaphylactic shock rare, 2% x x x x x x x
Haemolytic anaemia rare x x x x x x x
Oedema rare x x x x x x
Rash rare x x x x x
Hepatitis rare x x x x x x
Hypersensitivity rare x x x x x x x
Immune system disorder rare x
Jaundice rare x x x x x x
Liver disorder rare x x x x x x
Pruritus rare x x x x x
Pulmonary fibrosis rare x x x x x x x
Stomatitis rare x x x x
Urticaria rare x x x x x x
Liver function test abnormal rare x x x x x x x
Unspecified disorder of skin and subcutaneous tissue rare x
Interstitial pneumonia rare x x x x x x
Amenorrhoea x
Anorexia x
Arrhythmia x
Atrial fibrillation x
Bronchospasm x x x
Neoplasm malignant x x x
Chest pain x
Infection x x
Connective tissue disorder x
Cough x
Cystitis x
Dermatitis x
Dyspnoea x x x
Extravasation x
Fatigue x
Flushing x x
Gastrointestinal disorder x
Cardiac arrest x x x x x x
Haemorrhage x
Venoocclusive liver disease x
Hyponatraemia x
Hypotension x x x
Infertility x
Renal failure acute x
Leukaemia x
Lymphoma x
Mediastinal disorder x
Neoplasm x
Neutropenia x x
Pain x x
Pancytopenia x x x x x
Rales x
Rhabdomyolysis x x
Convulsion x
Skin ulcer x x
Tachycardia x x x
Ulcer x
Ureteric obstruction x
Urinary tract disorder x
Vasculitis x x x x x
Wound x
Acute leukaemia x
Mouth ulceration x x x x
Impaired healing x
Skin necrosis x x
Arterial thrombosis x
Fatal outcomes x x
Digestion impaired x x
Muscle necrosis x x
Hepatobiliary disease x
Radiation myelopathy x
Muscle damage x
Transaminases increased x
Respiratory distress x
Cutaneous hypersensitivity x x x x
Hyperuricaemia x
Febrile neutropenia x
Blood and lymphatic system disorders x
Local reaction x
Myelosuppression x x
Pulmonary toxicity x
Venoocclusive disease x x x
Bladder irritation x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

MELPHALAN / ALKERAN

Side effects:18
Source:FDA

MELPHALAN

Side effects:25
Source:FDA Structured Product Label

MELPHALAN

Side effects:37
Source:FDA Structured Product Label

MELPHALAN / ALKERAN

Side effects:51
Source:Health Canada

Melphalan

Side effects:65
Source:BC Cancer

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label