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Metformin

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: A10BA02

Side effects

Options: Show MedDRA Preferred Terms,   display all 38 labels

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Diarrhoea very common, 9.6% - 53.2% 2.6% - 11.7% x x x x x x x x x x x x x x x x x x
Gastrointestinal disorder common, 42% - 48.3% x x x x
Nausea very common, 6.5% - 25.5% 1.5% - 8.3% x x x x x x x x x x x x x x x x x
Vomiting very common, 3.45% - 25.5% 1.5% - 8.3% x x x x x x x x x x x x x x x x
Infection 20.5% - 20.9% x x x x
Anorexia very common x x x x x
Gastrointestinal symptom NOS very common x x x x x x
Abdominal bloating very common x x x x
Hypoglycaemia 13.7% 4.9% x x x x x x x x x x x
Flatulence very common, 12.1% 5.5% x x x x x x x x x x x x x x
Asthenia 9.2% 5.5% x x x x x x x
Accidental injury 5.58% - 7.31% x x
Dyspepsia 4.2% - 12.5% 4.1% x x x x x x x x x x
Abdominal discomfort 6.4% 4.8% x x x x x
Headache 4.7% - 5.7% 4.8% x x x x x x x x
Constipation 2.87% - 5.02% x x x x x
Abdominal pain 4.02% - 7.39% x x x x x x x x x
Rhinitis 4.2% - 5.6% x x
Dysgeusia common, 3% x x x x x x x
Taste metallic 3% x x x x x x
Abdominal distension 0.575% - 7.89% x x
Dermatitis very rare, common x x x x
Rash very rare, common x x x x x x x x x x x x x
Hepatitis very rare x x x
Acidosis x x
Anaemia megaloblastic x x x x x x
Angina unstable x
Breast disorder x
Chest pain x x
Connective tissue disorder x x
Contusion x x
Dehydration x x x x
Distention x x x x
Dizziness x x x x x x
Drowsiness
Dyspnoea x x x x x x x x
Ear pain x x
Eye disorder x
Fatigue x
Flushing x x x x x x x x
Seasonal allergy x x
Cardiac disorder x
Heartburn x x x x
Blood disorder x
Hypertension x x
Hypoaesthesia x x
Hypotension x
Body temperature decreased x
Immune system disorder x x
Influenza x x x x x x x x
Lethargy x
Mediastinal disorder x x
Cramp muscle x x
Fungal infection x x
Nail disorder x x x x x x x x
Nasal congestion x x
Nervous system disorder x x x
Neutropenia x
Pain in extremity x x
Palpitations x x x x x x x x
Pancreatitis x
Paraesthesia x
Pruritus x x x
Sinus headache x x
Syncope x
Taste disorders x x x x x x x x
Thrombocytopenia x
Tonsillitis x x
Toothache x x
Tremor x x
Erythema x x x x x
Upper respiratory tract infection x x x x
Urticaria x x x
Angiopathy x x
Muscle strain x x
Chills x x x x x x x x
Oedema peripheral x
Migraine x
Liver function test abnormal x
Sinus congestion x
Viral diarrhoea x x
Ketonuria x
Abnormal faeces x x x x x x x x
Malnutrition x x
Unspecified disorder of skin and subcutaneous tissue x x x
Lightheadedness x x x x x x x x
Ketoacidosis x x
Malaise x
Myalgia x x x x x x x x x x x
Abdominal pain upper x x
Function kidney decreased
Abdominal distress x
Upset stomach x x
Ketonemia x
Chest discomfort x x x x x x x x
Azotaemia x
Hepatobiliary disease x
Vision blurred x
Rigors x
Bradycardia x
Neuropathy x x x x
Respiratory distress x
Tooth abscess x x
Reaction gastrointestinal x x x
Azotemia prerenal x x x x
Emotional distress x
Sweating increased x x x x x x x x
White blood cell count increased x
Infestation NOS x x
Ear and labyrinth disorders x x
Oedema aggravated x
Vitamin B12 absorption decreased x x x x
Rhinorrhoea x
Epigastric discomfort x
Appetite absent x
Loose stools x x
Gastrointestinal tract irritation x
Somnolence x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

METFORMIN

Side effects:7
Source:FDA Structured Product Label

metformin

Side effects:13
Source:FDA Structured Product Label

METFORMIN

Side effects:13
Source:FDA Structured Product Label

METFORMIN HYDROCHLORIDE / RATIO-METFORMIN

Side effects:14
Source:Health Canada

METFORMIN

Side effects:14
Source:FDA Structured Product Label

METFORMIN HYDROCHLORIDE / PMS-METFORMIN - TAB 500MG

Side effects:15
Source:Health Canada

METFORMIN

Side effects:15
Source:FDA Structured Product Label

Metformin hydrochloride / Diabex

Side effects:17
Source:medicines.org.au

METFORMIN HYDROCHLORIDE / CO METFORMIN, 500MG

Side effects:22
Source:Health Canada

METFORMIN HYDROCHLORIDE / GLUCOPHAGE

Side effects:22
Source:Health Canada

METFORMIN

Side effects:22
Source:FDA Structured Product Label

METFORMIN

Side effects:22
Source:FDA Structured Product Label

METFORMIN

Side effects:24
Source:FDA Structured Product Label

METFORMIN

Side effects:26
Source:FDA Structured Product Label

METFORMIN

Side effects:26
Source:FDA Structured Product Label

METFORMIN

Side effects:29
Source:FDA Structured Product Label

METFORMIN HYDROCHLORIDE / GLUMETZA

Side effects:40
Source:FDA

METFORMIN HYDROCHLORIDE / GLUMETZA

Side effects:62
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label