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Mitoxantrone

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01DB07

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11
Nausea 0% - 76% 20% x x x x x x x x x x x
Upper respiratory tract infection 51% - 53% 52% x x x x x x
Menstrual disorder 26-61% - 61% 26% x x x x x
Vomiting 31% - 72% x x x x x x x x x x x
Haemoglobin decreased 43% - 48% x x x x
Body temperature increased 18% - 78% x x x x x x x x x x x
Amenorrhoea 0% - 53% 3% x x x x x x x
Alopecia 0% - 61% 31% x x x x x x x x x x x
Thrombocytopenia 33-39% x x x x x x x
Sepsis 18% - 36% x x x x x x x x x x
Urinary tract infection 29% - 32% 13% x x x x x x
Haemorrhage 6% - 41% x x x x x x x
Pain 8-41% x
Asthenia 0% - 24% x x x x x x x x x x x
Anorexia 22-25% x x x x x x x x x x x
Mucosal inflammation 8% - 33% x x x x x x x x x x x
Blood urea increased 22% x
Diarrhoea 8% - 47% 11% x x x x x x x x x x x
Oedema 10-31% x x x x x x x
Hyperglycaemia 10-31% x x x x x
Infection 5% - 73% x x x x x x x
Leukopenia 9% - 9-100% 0% x x x x x x x x x x x
Stomatitis 8% - 33% 8% x x x x x x x x x x x
White blood cell count decreased 14% - 100% x x x x
Constipation 10% - 14% 6% x x x x x x x x
Serum creatinine increased 13% x
Dyspnoea 0% - 20% x x x x x x x x x x x
Pharyngitis 5% - 19% x x x x
Haematuria 11% x x x x x
Fungal infection 6% - 15% x x x x
Onycholysis 11% x x x x x x
Hypocalcaemia 10% x x x x x x x x x x
Ulcer 10% x
Dyspepsia 5-14% x x x x x
Stomach ache 5% - 14% x x x x
Epigastric pain 5% - 14% x x x x
Abdominal pain 4% - 15% x x x x x x x x x x x
Anaemia 6% - 5-75% 2% x x x x x x x x x x x
Cough 2% - 13% x x x x x
Gastrointestinal haemorrhage 2-16% x x x x x x x
Hyponatraemia 9% x x x x x
Pneumonia 0% - 9% x x x x x x x
Gamma-glutamyltransferase increased 3% - 15% 3% x x x x
Sweating increased 9% x
Hypokalaemia 7-10% x x x x x
Contusion 6-11% x x x x x x x
Aspartate aminotransferase increased 8% - 9% 8% x x x x
Back pain 6% - 8% 5% x x x x x
Ecchymosis 2% - 11% x x x x
Petechiae 2% - 11% x x x x
Urine abnormality 5% - 11% 6% x x x x
Electrocardiogram abnormal 5% - 11% 3% x x x x
Nephropathy toxic 8% x x x
Erectile dysfunction 7% x x x x x
Agranulocytosis 6% 2% x x x x x x
Arrhythmia 3% - 18% 8% x x x x x x x x x x x
Headache 6% - 13% 5% x x x x x x x
Proteinuria 6% x x x x x
Sinusitis 3% - 6% 2% x x x x x
Alanine aminotransferase increased 5% - 6% 3% x x x x
Anxiety 5% x x x x x x x x x x
Arthralgia 5% x x x x x
Fungal skin infection 0% - 10% x x x x
Foot and mouth disease 0% - 10% x x x x
Ischaemia 5% x
Jaundice 0% - 8% x x x x x x
Rhinitis 0% - 10% x x x x x
Myalgia 5% x x x x x
Glucose increased 5% - 10% x x x x
Hypertension 4% x x x x x
Renal failure 0% - 8% x x x x
Convulsion 2% - 8% x x x x x
Menorrhagia 0% - 7% x x x x
Vision blurred 3% x x x x x
Conjunctivitis 0% - 5% x x x x x
Anaphylactic shock 1% x x x x x x x x x
Tumour lysis syndrome 1% x x x x x x
Chest pain x x x x x x x
Confusional state x x x x x x
Sudden death x
Dehydration x x x x
Drowsiness x x x
Endometritis x x x x
Enteritis x x x x
Rash x x x x x x x x x x
Extravasation x x x x x x x x x x x
Fatigue x x x x x x x x x x x
Cardiac failure x
Cardiac failure congestive x x x x x x x x x x
Hepatitis x x x x x x
Hyperkalaemia x x x x x
Hypersensitivity x x x x x x x x x x x
Hypotension x x x x x x x x x x
Infertility x x x x
Renal failure acute x
Acute promyelocytic leukaemia x x
Non-Hodgkin's lymphoma x
Myelodysplastic syndrome x x x
Myocardial infarction x x x x x x x
Necrosis x x x x x x x x x x x
Metastasis x
Neutropenia x x x x x x
Paraesthesia x x x x x x
Phlebitis x x x x x x x x x x
Shock x x
Skin disorder x x x x
Skin infection x x x x
Sweating x x x x
Swelling x x x x x x x x x
Tachycardia x x x x x x x
Tonsillitis x x x x
Erythema x x x x x x x x x
Ureteric obstruction x
Urticaria x x x x x x x
Viral infection x x x x
Weight increased x x x x
Weight decreased x x x x
Chills x x x x
Sinus bradycardia x x x
Hyperphosphataemia x x x x x
Haemorrhage intracranial x x x x
Myocardial ischaemia x x x x
Bone marrow depression x x x x x x
Bone pain x x x x
Interstitial pneumonia x x x x x x x
Malaise x x x x
Breast cancer stage IV x
Blood bilirubin increased x x x x x
Anaphylactoid reaction x x x x x x
Platelet count decreased 0% - 33% x x x x
Lymphocyte abnormal x x x x
Bradycardia x x x
Blood urea abnormal x x x x
Urine color abnormal x
Affective disorder x x x x
Platelet count abnormal x x x x
Hyperuricaemia x x x x x x
Taste altered x x x x
Creatinine abnormal NOS x x x x
Febrile neutropenia x x x x x
Local reaction x
Myelosuppression x x x x x x x x x x x
Elevated liver enzyme levels x x x x x x
Potassium low 0% - 10% x x x x
Cardiotoxicity x x
Cardiomyopathy x x x x x x x
Left ventricular ejection fraction decreased x x x x x
Nail pigmentation x x x x x x x
Urine output x
Cross resistance x
Somnolence x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Mitozantrone (as hydrochloride) / Name of the drug

Side effects:50
Source:medicines.org.au

Mitoxantrone

Side effects:75
Source:BC Cancer

MITOXANTRONE

Side effects:111
Source:FDA Structured Product Label

MITOXANTRONE

Side effects:111
Source:FDA Structured Product Label

MITOXANTRONE

Side effects:111
Source:FDA Structured Product Label

MITOXANTRONE

Side effects:111
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label