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Levonorgestrel

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: G03AC03

Side effects

Options: Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14
Haemorrhage Haemorrhage 1.73% - 31% x x x x x x x x x x x x
Haemoglobin Haemorrhage 1.73% - 31% x x x x x x x x x x x x
Vulvovaginitis Vulvovaginitis 20.2% x x x x
Amenorrhoea Amenorrhoea 9.8% - 23.9% x x x x x x
Abdominal pain Abdominal pain postmarketing, 2.5% - 20.9% x x x x x x x x x x
Gastrointestinal pain Abdominal pain postmarketing, 2.5% - 20.9% x x x x x x x x x x
Asthenia Fatigue postmarketing, 8% - 36.8% x x x x x x x x x
Asthenia 8% - 16.9% x x
Fatigue Fatigue postmarketing, 8% - 36.8% x x x x x x x x x
Nausea Nausea postmarketing, 5.5% - 50.5% x x x x x x x x x x x x x x
Menometrorrhagia Menometrorrhagia 9.6% - 20.5% x
Abdominal pain lower Abdominal pain lower 13% - 14.4% x x x x
Ovarian cyst Ovarian cyst 12% - 13.2% x x x x x x
Corpus luteum cyst x
Dizziness Dizziness postmarketing, 3.7% - 23.1% x x x x x x x x x x
Syncope x
Lightheadedness x
Breast tenderness Breast tenderness 8.19% - 20.8% x x x x x x x x x x
Headache Headache postmarketing, 5.6% - 20.2% x x x x x x x x x x x x x x
Seborrhoeic dermatitis Seborrhoeic dermatitis 2.9% - 15% x x
Discomfort Discomfort 8.6% x
Migraine Migraine 7.7% x x x x x x x
Mood swings Mood swings 6.4% x x x x
Affect lability Mood swings 6.4% x x x x
Menorrhagia Menorrhagia 1.6% - 25.9% x x x
Diarrhoea Diarrhoea 3.2% - 6.54% x x x x x
Device expulsion IUD expelled 4.9% x x
Device expulsion 3.2% x
Pain Pain 4.9% x x x x
Vaginal discharge Vaginal discharge 4.9% x x x x x
Leukorrhea x
Metrorrhagia Metrorrhagia 4.3% x x x x x
Polymenorrhoea Polymenorrhoea 2.7% - 5% x
Vomiting Vomiting postmarketing, 1.2% - 22.4% x x x x x x x x x x
Vaginal haemorrhage Vaginal haemorrhage 1.02% - 4.25% x x x x x x
Hypomenorrhoea Hypomenorrhoea 1.5% - 2.9% x
Muscle spasms Muscle spasms 2% x
Cramps of lower extremities x
Influenza Influenza 0.919% - 1.02% x
Angioedema Angioedema postmarketing x x x x
Breast disorder Breast disorder postmarketing, 20.2% x x x x x x x
Dysmenorrhoea Dysmenorrhoea postmarketing, 8.6% x x x x x x x x x x
Dermatitis Rash postmarketing x x x x x x x
Dermatitis x
Rash Rash postmarketing x x x x x x x
Gastrointestinal disorder Gastrointestinal disorder postmarketing x x x x x x x
Hypersensitivity Hypersensitivity postmarketing x x x
Nervous system disorder Nervous system disorder postmarketing, 12.4% x x x x x x x
Oligomenorrhoea Oligomenorrhoea postmarketing, 9.5% - 12.8% x x x x x x x
Pelvic pain Pelvic pain postmarketing, 1.8% - 18.9% x x x x x x x x x x
Urticaria Urticaria postmarketing x x x x x
Menstruation irregular Menstruation irregular postmarketing x x x x
Device breakage Device breakage postmarketing x x x x
Abdominal distension Abdominal distension x x x
Enlargement abdomen x
Abdominal bloating x
Acute tonsillitis Acute tonsillitis x
Alopecia Alopecia x x x x x x
Anaemia Anaemia x x x
Hypochromic anaemia Hypochromic anaemia x
Decreased appetite Anorexia x
Anxiety Anxiety x
Arrhythmia Arrhythmia x
Asthma Asthma x x
Back pain Back pain x x x x x
Mental disorder Mental disorder x x x
Breast cancer Breast cancer x x
Bronchitis Bronchitis x x
Candida infection Candida infection x
Cervicitis Cervicitis x x x x x
Chest pain Chest pain x
Infection Infection x x x
Connective tissue disorder Connective tissue disorder x
Constipation Constipation x x
Contusion Contusion x
Cough Cough x
Cystitis Cystitis x x
Bladder pain Cystitis x x
Cystitis noninfective Cystitis x x
Cyst Cyst x x
Libido decreased Libido decreased x x x x x x
Disturbance in sexual arousal Libido decreased x x x x x x
Libido increased x
Depression Depression x x
Dermatitis contact Dermatitis contact x
Dyspepsia Dyspepsia x
Dyspnoea Dyspnoea x
Dysuria Dysuria x
Eczema Eczema x x x x
Oedema Oedema x x x x
Endocrine disorder Endocrine disorder x
Endometriosis Endometriosis x
Endometritis Endometritis x
Eye disorder Eye disorder x
Body temperature increased Body temperature increased x
Flatulence Flatulence x
Gas in stomach x
Abdominal bloating x
Folliculitis Folliculitis x
Cardiac disorder Cardiac disorder x
Haematoma Haematoma x
Haemorrhoids Haemorrhoids x
Herpes simplex Herpes simplex x
Hirsutism Hirsutism x x x x x
Hypertension Hypertension x x x x x
Hypertrichosis Hypertrichosis x x
Hypoaesthesia Hypoaesthesia x
Numbness x
Immune system disorder Immune system disorder x x
Libido increased Libido increased x
Pain in extremity Leg pain x
Mastitis Mastitis x
Breast pain Breast pain x x x x
Mediastinal disorder Mediastinal disorder x
Chloasma Chloasma x
Menstrual disorder Menstrual disorder x
Musculoskeletal pain Musculoskeletal pain x
Neoplasm Neoplasm x
Nervousness Nervousness x x x x x
Tension Nervousness x x x x x
Sensory loss Numbness x
Ear infection Otitis x
Otitis media Otitis media x
Ovarian disorder Ovarian disorder x
Palpitations Palpitations x x
Papilloma Papilloma x
Pharyngitis Pharyngitis x x x
Pneumonia Pneumonia x
Polyp Polyp x
Pregnancy Pregnancy x x x
Ectopic pregnancy Ectopic pregnancy x x x x
Premenstrual syndrome Premenstrual syndrome x
Premenstrual tension x
Pruritus Pruritus x x x x x
Pruritus genital Pruritus genital x
Purpura Purpura x
Vascular purpura Purpura x
Rhinitis Rhinitis x x x
Sciatica Sciatica x
Sinusitis Sinusitis x x x
Skin disorder Skin disorder x x x x
Unspecified disorder of skin and subcutaneous tissue x x x
Shock Syncope x
Syncope Syncope x
Loss of consciousness Syncope x
Tendonitis Tendonitis x
Tooth disorder Tooth disorder x
Toothache Toothache x
Upper respiratory tract infection Upper respiratory tract infection x x
Pollakiuria Pollakiuria x
Urinary incontinence Urinary incontinence x
Urinary tract infection Urinary tract infection x
Urethral disorder Urinary tract disorder x
Urinary tract disorder Urinary tract disorder x
Uterine disorder Uterine disorder x
Uterine leiomyoma Uterine leiomyoma x
Uterine haemorrhage Uterine haemorrhage x
Uterine perforation Uterine perforation x
Vaginal neoplasm Vaginal neoplasm x
Varicose vein Varicose vein x
Vertigo Vertigo x
Vulval disorder Vulval disorder x x
Weight increased Weight increased x x x x x x
Weight decreased Weight decreased x x
Polydipsia Polydipsia x
Appendicitis Acute appendicitis x
Genital ulceration Genital ulceration x
Application site reaction Application site reaction x
Dry skin Dry skin x
Uterine enlargement Uterine enlargement x
Streptococcal sepsis Streptococcal sepsis x x x
Haemoglobin decreased Haemoglobin decreased x
Malnutrition Malnutrition x
Fibroadenoma of breast Fibroadenoma of breast x
Fibroadenosis of breast x
Contact lens intolerance Contact lens intolerance x
Myalgia Myalgia x
Musculoskeletal discomfort Myalgia x
Muscle twitching Muscle twitching x
Increased appetite Increased appetite x
Tenderness Tenderness x
Cervix disorder Uterine cervical lesion x
Galactorrhoea Galactorrhoea x x
Medical device complication IUD complication x
Menstruation delayed Menstruation delayed x
Perineal pain Perineal pain x
Pelvic inflammatory disease Pelvic inflammatory disease x x x x
Erythema Redness x
Depressed mood Depressed mood x x x
Benign breast neoplasm Benign breast neoplasm x
Influenza like illness Influenza-like symptoms x x
Vaginal infection Vaginal infection x
Crying Tearfulness x
Tearfulness Tearfulness x
Chapped lips Chapped lips x
Vulvovaginal mycotic infection Vaginal mycosis x
Blood glucose increased Blood glucose increased x
Hyperhidrosis Sweating increased x
Acne Acne x x x x x
Exacerbation of acne x
Genital infection Genital infection x
Infestation Infestation NOS x
Smear cervix normal Smear cervix normal x x x
Protein urine present Urinary protein increased x
Insomnia Insomnia x
Genital discharge Genital discharge x x
Breast discomfort Breast tension x
Dyspareunia Dyspareunia x x x x x
Breast neoplasm Breast neoplasm x
Somnolence Somnolence x
Visual impairment Abnormal vision x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

LEVONORGESTREL / PLAN B

Side effects:46
Source:Health Canada

LEVONORGESTREL

Side effects:9
Source:FDA Structured Product Label

LEVONORGESTREL

Side effects:16
Source:FDA Structured Product Label

LEVONORGESTREL

Side effects:16
Source:FDA Structured Product Label

LEVONORGESTREL

Side effects:16
Source:FDA Structured Product Label

LEVONORGESTREL

Side effects:16
Source:FDA Structured Product Label

Levonorgestrel Tablets / Microlut, Tablet

Side effects:26
Source:Medsafe

LEVONORGESTREL / NORPLANT II

Side effects:75
Source:FDA

LEVONORGESTREL

Side effects:36
Source:FDA Structured Product Label

LEVONORGESTREL / MIRENA

Side effects:37
Source:FDA

LEVONORGESTREL

Side effects:41
Source:FDA Structured Product Label

LEVONORGESTREL

Side effects:42
Source:FDA Structured Product Label

LEVONORGESTREL / MIRENA

Side effects:106
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label