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Ritonavir

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: J05AE03

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4
Nausea 23.1% - 46.6% 5.7% - 8.4% x x x x
Diarrhoea 0% - 25% 6.1% - 7.9% x x x x
Vomiting 12.6% - 23.3% 2.6% - 4.4% x x x x
Asthenia 9.4% - 28.4% 5.3% - 6.4% x x x x
Dysgeusia 5.4% - 17.2% 1.7% - 2.2% x x x x
Neutropenia 9% x x
Hyperamylasaemia 7% x x
Headache 5.1% - 7.8% 4% - 5.7% x x x
Anorexia 0.9% - 8.6% 2% - 4.2% x x x
Thrombocytopenia 5% x x x x
Abdominal pain 3.4% - 8.3% 3.1% - 5.1% x x x x
Circumoral paresthesia 0% - 6.7% 0.2% - 0.4% x x x
Anaemia 4% x x x x
Dyspepsia 0% - 5.9% 0.7% - 1.5% x x x x
Malaise 0.7% - 5.2% 0.2% x x x
Dizziness 1.7% - 5.2% 1.1% x x x x
Body temperature increased 0.9% - 5% 2.2% - 2.4% x x x
Aspartate aminotransferase increased 3% x x
Paraesthesia 0% - 6% 0.2% - 1.1% x x x x
Sweating 1.7% - 3.4% 1.1% x x x
Insomnia 0.8% - 3.4% 1.8% x x x
Somnolence 0% - 2.6% 0.2% x x x
Local throat irritation 0.8% - 2.8% 0.2% - 0.4% x x x
Myalgia 0.8% - 2.4% 0.9% - 1.1% x x x x
Rash 0% - 3.5% 0.9% - 1.5% x x x x
Depression 1.7% - 2.5% 0.7% x x
Vasodilation 0.8% - 3.4% 0% x x x
Fasting 1.3% - 9.9% 0.3% - 0.4% x x x x
Flatulence 0.8% - 2.6% 0.7% x x x x
Pain 0.8% - 2.2% 1.8% x x x
Pharyngitis 0% - 2.6% 0.4% x x x
Anxiety 0% - 1.7% 0.9% x x x
Constipation 0% - 3.4% 0.4% x x x
Thinking abnormal 0% - 2.6% 0.4% x x x
Confusional state 0% - 0.9% 0.6% x x x x
Breast disorder postmarketing x x
Cushing's syndrome postmarketing x x x
Dehydration postmarketing x x x x
Diabetes mellitus postmarketing x
Endocrine disorder postmarketing x
Toxic epidermal necrolysis postmarketing x x
Cardiac disorder postmarketing x
Factor VIII deficiency postmarketing x
Haemorrhage postmarketing x x x
Hyperglycaemia postmarketing x x
Hypotension postmarketing x x x x
Orthostatic hypotension postmarketing x x x x
Ischaemia postmarketing x x x
Menorrhagia postmarketing x x x
Myocardial infarction postmarketing x x x
Nervous system disorder postmarketing x x x
Convulsion postmarketing x x x x
Syncope postmarketing, 0.6% - 1.7% 0% x x x x
Atrioventricular block first degree postmarketing x
Bundle branch block right postmarketing x
Vasospasm postmarketing x x x
Atrioventricular block complete postmarketing x
Malnutrition postmarketing x x x x
Unspecified disorder of skin and subcutaneous tissue postmarketing x x
Atrioventricular block second degree postmarketing x
Secondary adrenocortical insufficiency postmarketing x x x
Gastrointestinal symptom NOS postmarketing x x x x
Haemophilia postmarketing x
Drug interaction postmarketing x x x
Fat redistribution postmarketing x
Renal impairment postmarketing x x x x
Albuminuria x x
Amblyopia x x x
Amnesia x x x
Aphasia x x x
Arthralgia 0% - 1.7% 0.7% x x x x
Arthritis x x
Asthma x x x
Ataxia x x x
Back pain x x x x
Mental disorder x
Blepharitis x x x
Bone disorder x x
Bronchitis x x
Cachexia x x x
Oral candidiasis x x
Cardiovascular disorder x x
Neck pain x x x
Cheilitis x x x
Chest pain x x x
Cholangitis x x
Colitis x x x
Colitis ulcerative x x
Coma x x
Conjunctivitis x x
Connective tissue disorder x
Cough x
Cystitis x x
Libido decreased x x x
Dysphagia x x x
Depersonalisation x x
Dermatitis exfoliative x x
Dermatitis contact x x x
Fungal skin infection x x
Diplopia x x x
Dyspnoea x x x
Dysuria x x x
Ear pain x x x
Ecchymosis x x x
Eczema x x x
Oedema x x x x
Grand mal convulsion x x x
Epistaxis x x x
Eructation x x x
Erythema multiforme x x
Oesophagitis x x x
Eye disorder x x x
Facial pain x x x
Fatigue x
Faecal incontinence 0% 0% x x
Flushing x
Folliculitis x x x
Furunculosis x x
Gastritis x x x
Gastroenteritis x x x
Gastrooesophageal reflux disease x
Gastrointestinal disorder x x x x
Gastrointestinal haemorrhage x x x x
Gingivitis x x x
Glycosuria x x x
Gout x x x x
Hallucination x x x
Subdural haematoma x x
Haematuria x x x
Coma hepatic x x
Hepatitis x x x x
Hepatomegaly x x x
Hepatosplenomegaly x x
Hiccups x x x
Hypercholesterolaemia x x x x
Hyperaesthesia x x x
Hyperlipidaemia x
Hypersensitivity x x x x
Hypertension x x x
Hypertriglyceridaemia x
Hypoaesthesia x x
Body temperature decreased x x x
Ileitis x x
Immune system disorder x
Influenza x x x
Iritis x x x
Jaundice x x
Jaundice cholestatic x
Arthropathy x x x
Calculus of kidney x x x
Renal failure acute x x
Laryngeal oedema x x
Cramps of lower extremities x x
Acute myeloid leukaemia x x
Leukopenia x x x
Lung disorder x x x
Lymphocytosis x x x
Breast pain x x
Mediastinal disorder x
Melaena x x
Molluscum contagiosum x x x
Cramp muscle x x x
Myopathy x
Myeloproliferative disorder x x
Myositis x x x
Nervousness x x x
Neuralgia x x x
Nocturia 0% - 0.2% 0% x x x
Palpitations x x x
Pancreatitis x x x x
Pelvic pain x x
Penis disorder x x x
Abscess periodontal x x
Neuropathy peripheral x x x x
Personality disorder x x x
Phlebitis x x
Polyuria x x x
Pruritus x x x x
Psoriasis x x x
Pyelonephritis x x
Rectal disorder x x x
Renal failure x x x
Rhinitis x x x
Scotoma x x x
Seborrhoeic dermatitis x x x
Sialoadenitis x x
Sinusitis x x
Skin disorder x x
Speech disorder x x
Stomatitis x x
Tachycardia x x x
Thirst x x x
Thrombosis x
Onychomycosis x x
Tinnitus x x x
Tremor x x x
Urethritis x x x
Pollakiuria x x x
Urinary tract infection x x
Urinary tract disorder x
Urticaria x x x
Uveitis x x x
Vaginal inflammation x x
Angiopathy x
Vertigo x x x
Vestibular disorder x x
Weight decreased 0% - 2.4% 1.7% x x x
Xanthomatosis x x
Dry mouth x x x
Urinary retention x x x
Peripheral vascular disorder x x x
Chills x x x
Stupor x x
Agitation x x x
Mood swings x x x
Photophobia x x x
Rash pustular x x
Oedema peripheral x x x x
Mouth ulceration x x x
Migraine x x x
Peripheral sensory neuropathy x x
Neck stiffness x x x
Alcohol intolerance x x
Hormone level abnormal x x x
Blood urea increased x x
Creatine phosphokinase increased x
Diarrhoea haemorrhagic x x x
Tongue oedema x x
Enzyme abnormality x x
Skin hypertrophy x x
Accidental injury x x x
Kidney function abnormal x x
Hepatocellular injury x x x
Liver function test abnormal x
Manic psychosis x x
Melanoma skin x x
Muscular weakness x x x
Bone pain x x
Retrosternal pain x x x
Eye pain x x x
Vesiculobullous rash x x x
Skin discolouration x x
Dry skin x x x
Cerebral venous thrombosis x
Oesophageal ulcer x x
Vitreous disorder x x
Abnormal faeces x x x
External ophthalmoplegia x x
Photosensitivity reaction x x x
Interstitial pneumonia x x x
Muscle twitching x x x
Rectal tenesmus x x x
Disturbance in attention x
Abnormal dreams x x x
Euphoric mood x x x
Hepatotoxicity x
Erectile dysfunction x x
Rectal haemorrhage x x
Hepatobiliary disease x
Peripheral coldness x
Blood bilirubin increased x
Electrolyte imbalance x
Vision blurred x x x x
Avitaminosis x x x
Enlargement abdomen x x x
Adrenal cortical hypofunction x x
Rash maculo-papular x x x
Hyperkinesia x x
Neuropathy x x x
Electroretinogram abnormal x x x
Lymphadenopathy x x x
Dementia x x
Coordination abnormal x x x
Paraesthesia oral x
Paralysis x x x
Face oedema x x x
Renal pain x x x
Cough increased x x x
Gait disturbance x x x
Acne x x x x
Sleep disorder x x
Lipodystrophy acquired x
Cerebral ischaemia x x
Pseudomembranous colitis x x
Ileus x x
Hearing impaired x x x
Parosmia x x x
Oropharyngeal pain x
Ageusia x x x
Feeling hot x
Hypoventilation x x x
Abnormal vision x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

RITONAVIR

Side effects:81
Source:FDA Structured Product Label

ritonavir capsules / Norvir

Side effects:248
Source:FDA

RITONAVIR / NORVIR SEC

Side effects:251
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label