Spironolactone

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

Hide MedDRA Preferred Terms

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8
Agranulocytosis def Agranulocytosis def x x x x x x x x
Amenorrhoea def Amenorrhoea def x x x x x x x x
Anaphylactic shock def Anaphylactic shock def x x x x x x x x
Ataxia def Ataxia def x x x x x x x x
Neoplasm malignant def Carcinoma def x x x x x x x x
Confusional state def Confusional state def x x x x x x x x
Feeling abnormal Confusional state def x x x x x x x x
Drug eruption def Drug eruption def x x
Diarrhoea def Diarrhoea def x x x x x x x x
Somnolence def Drowsiness def x x x x x x x x
Eosinophilia def Eosinophilia def x x
Toxic epidermal necrolysis def Toxic epidermal necrolysis def x x
Necrolysis epidermal x x
Dermatitis def Rash def x x x x x x x x
Rash def Rash def x x x x x x x x
Eruption x x x x x x x x
Body temperature increased def Body temperature increased def x x x x x x x x
Gastritis def Gastritis def x x x x x x x x
Gynaecomastia def Gynaecomastia def x x x x x x x x
Headache def Headache def x x x x x x x x
Haemorrhage def Haemorrhage def x x x x x x x x
Haemoglobin def Haemorrhage def x x x x x x x x
Hyperkalaemia def Hyperkalaemia def x x x x x x x x
Hypersensitivity def Hypersensitivity def x x x x x x x x
Lethargy def Lethargy def x x x x x x x x
Muscle spasms def Cramp muscle def x x x x x x x x
Nausea def Nausea def x x x x x x x x
Postmenopausal haemorrhage Postmenopausal haemorrhage x x x x x x x x
Renal failure def Renal failure def x x x x x x x x
Ulcer def Ulcer def x x x x x x x x
Urticaria def Urticaria def x x x x x x x x
Vasculitis def Vasculitis def x x x x x x x x
Vomiting def Vomiting def x x x x x x x x
Menstruation irregular def Menstruation irregular def x x x x x x x x
Gastric haemorrhage def Gastric haemorrhage def x x x x x x x x
Breast cancer def Carcinoma breast def x x x x x x x x
Indication Labels
Adenoma benign def x x x x x x
Ascites def x x x x x x x x
Cardiac failure def x x x x x x
Cardiac failure congestive def x x x x x x
Cardiovascular disorder def x x x x x x
Discomfort def x x x x x x
Essential hypertension def x x x x x x
Fluid overload def x x x x x x
Generalised oedema x x x x x x
Gravitational oedema x x x x
Hepatic cirrhosis def x x x x x
Hyperaldosteronism def x x x x x x
Hypernatraemia def x x x x x
Hyperplasia def x x x x x x
Hyperplasia adrenal def x x x x x x
Hypertension def x x x x x x
Hypokalaemia def x x x x x x x x
Nephrotic syndrome def x x x x x x x x
Normal pregnancy def x x x x x x
Oedema def x x x x x x x x
Pre-eclampsia def x x x x x
Primary hyperaldosteronism def x x x x x x
Toxemia def x x x x x x
Uterine disorder def x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: C03DA01

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. SPIRONOLACTONE : 29 side effects (FDA XML label)
  2. SPIRONOLACTONE : 29 side effects (FDA XML label)
  3. SPIRONOLACTONE : 29 side effects (FDA XML label)
  4. SPIRONOLACTONE : 29 side effects (FDA XML label)
  5. SPIRONOLACTONE : 29 side effects (FDA XML label)
  6. spironolactone : 29 side effects (FDA XML label)
  7. SPIRONOLACTONE : 33 side effects (FDA XML label)
  8. Spironolactone : 33 side effects (FDA XML label)