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Doxycycline hyclate

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Codes: None found

Side effects

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MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5
Headache Headache 25.8% 26% x x
Nasopharyngitis Common cold 22.1% 21.4% x x
Rhinitis Common cold 22.1% 21.4% x x
Influenza Flu symptoms 11.3% 18.6% x
Nausea Nausea 7.98% 5.58% x x x x x
Toothache Toothache 6.57% 13% x x
Dyspepsia Dyspepsia 6.1% 2.33% x x
Acid indigestion 3.76% 3.26% x
Tooth disorder Tooth disorder 6.1% 8.84% x
Arthralgia Arthralgia 5.63% 3.72% x
Musculoskeletal discomfort Arthralgia 5.63% 3.72% x
Myalgia 0.939% 2.79% x x
Diarrhoea Diarrhoea 5.63% 3.72% x x x x x
Sinus congestion Sinus congestion 5.16% 5.12% x
Oropharyngeal discomfort Throat sore 5.16% 6.05% x x
Oropharyngeal pain Throat sore 5.16% 6.05% x x
Cough Cough 4.23% 5.12% x x
Dysmenorrhoea Dysmenorrhoea 4.23% 2.33% x
Dermatitis Rash 3.76% 2.79% x x x x
Rash Rash 3.76% 2.79% x x x x
Pain Pain 3.76% 2.33% x x
Ache x
Sinus headache Sinus headache 3.76% 3.72% x
Bronchitis Bronchitis 3.29% 2.33% x x
Sinusitis Sinusitis 3.29% 8.37% x x
Back pain Back pain 1.88% - 3.29% 3.72% - 4.19% x x
Low back pain x
Infection Infection 1.88% 2.79% x
Myalgia Myalgia 0.939% 2.79% x x
Gingival pain Gingival pain 0.469% 2.79% x
Abscess Abscess x
Anaphylactic shock Anaphylactic shock x x x x
Haemolytic anaemia Haemolytic anaemia x x x x
Angioedema Angioedema x x x x
Decreased appetite Anorexia x x x x
Vulvovaginal candidiasis Vaginal moniliasis x
Vulvovaginal mycotic infection Vaginal moniliasis x
Dysphagia Dysphagia x x x x
Sensitivity of teeth Sensitivity of teeth x
Dermatitis exfoliative Dermatitis exfoliative x x x x
Enterocolitis Enterocolitis x x x x
Eosinophilia Eosinophilia x x x x
Oesophagitis Oesophagitis x x x x
Body temperature increased Body temperature increased x
Fistula Fistula x
Gingival bleeding Gingival bleeding x
Gingivitis Gingivitis x
Glossitis Glossitis x x x x
Hypersensitivity Hypersensitivity x x x x x
Hypertension Hypertension x
Inflammation Inflammation x
Systemic lupus erythematosus Systemic lupus erythematosus x x x x
Neutropenia Neutropenia x x x x
Osteopenia Osteopenia x
Tooth abscess Dentoalveolar abscess x
Abscess periodontal x
Pericarditis Pericarditis x x x x
Upper-airway cough syndrome Postnasal drip x
Benign intracranial hypertension Benign intracranial hypertension x x x
Pulpitis dental Pulpitis dental x
Henoch-Schonlein purpura Henoch-Schonlein purpura x x x x
Serum sickness Serum sickness x x x x
Skin infection Skin infection x
Aphthous stomatitis Aphthous stomatitis x
Swelling Swelling x
Thrombocytopenia Thrombocytopenia x x x x
Tooth fracture Tooth fracture x
Erythema Erythema x
Urticaria Urticaria x x x x
Vomiting Vomiting x x x x x
Tooth loss Tooth loss x
Essential hypertension Essential hypertension x
Oesophageal ulcer Oesophageal ulcer x x x x
Abdominal pain Stomach ache x
Abdominal pain upper Stomach ache x
Tension Tension x
Discomfort Discomfort x
Tenderness Tenderness x
Fontanelle bulging Fontanelle bulging x x x
Abdominal discomfort Upset stomach x
Hepatotoxicity Hepatotoxicity x x x x
Musculoskeletal pain Pain neck/shoulder x
Pain in jaw Pain in jaw x
Photosensitivity reaction Photosensitivity x x x x
Premenstrual syndrome Premenstrual tension x
Pre-menstrual tension syndrome x
Menorrhagia Prolonged menses x x
Dermatitis atopic Cutaneous hypersensitivity x
Nephropathy toxic Nephropathy toxic x x x
Ear infection Ear infection x
Insomnia Insomnia x
Oral pain Sore mouth x


Information about indications was extracted from the indications and usage sections of the labels.


Side effects:27


Side effects:29


Side effects:29


Side effects:47


Side effects:50

Color scheme:


    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    no frequency information
    not found on label