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Capecitabine

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01BC06

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Agranulocytosis 0.4% - 87% x x x x x x x x x x x x x x
Lymphopenia 15% - 98% x x x x x x x x x x x
Leukopenia 0.2% - 88% x x x x x x x x x x x x x x x x x
Aspartate aminotransferase increased 26% x
Blood bilirubin increased 6.3% - 50.3% x x x x x x x
Febrile neutropenia 3% - 21% x x x x x x x x x x x x x x x x
Stomatitis 1% - 62% x x x x x x x x x x x x x x x x x x x
Diarrhoea 1% - 65% x x x x x x x x x x x x x x x x x x x
Hand and foot syndrome secondary to sickle cell anaemia 1% - 60% x x x x x x x x x x x
Neutropenia 1% - 87% x x x x x x x x x x x x x x x x x x x
Eye irritation 1% - 15% x x x x x x x x x x x x x x x x x x x
Oral discomfort 10% x x x x x x x x x
Abdominal pain 1% - 35% x x x x x x x x x x x x x x x x x x x
Myalgia 2% - 25% x x x x x x x x x x x x x x x x x x x
Fatigue 1% - 46% x x x x x x x x x x x x x x x x x x x
Rash 6% - 8% x x x x x x x x x x x x x x
Constipation 1% - 18% x x x x x x x x x x x x x x x x x x x
Nail disorder 0.1% - 15% x x x x x x x x x x x x x x x x x x
Peripheral sensory neuropathy 4% - 10% x x x x x x x x x x x x x x x x
Insomnia 1% - 10% x x x x x x x x x x x x x x x x x x x
Alopecia 1% - 42% x x x x x x x x x x x x x x x x x x
Asthenia 1% - 46% x x x x x x x x x x x x x x x x x
Dermatitis 1% - 37% x x x x x x x x x x x x x x x x x x
Dizziness 1% - 8% x x x x x x x x x x x x x x x x x x x
Dysgeusia 1% - 14% x x x x x x x x x x x x x x x x x
Neuropathy peripheral 1% - 10% x x x x x x x x x x x x x x x x
Dyspepsia 1% - 8% x x x x x x x x x x x x x x x x x x x
Flushing 5% x x x x x x x x x x x x x x
Headache 1% - 15% x x x x x x x x x x x x x x x x x x x
Hyperbilirubinaemia 2% - 48% x x x x x x x x
Pharyngeal disorder 5% x x x x x x x x x
Pruritus 5% x x x x x x x x x x x x x x x x x
Weight decreased 5% x x x x x x x x x x x x x x x
Dry mouth 1% - 5% x x x x x x x x x x x x x x x x
Skin discolouration 1% - 7% x x x x x x x x x x x
Rash erythematous 1% - 5% x x x x x x x x x x x x x x
Influenza like illness 5% x x x x x x x x x x x x x x x
Mood alteration NOS 1% - 6% x x x x x x x x x
Hyperglycaemia 0.9% - 40.1% x x x x x x x x x
Conjunctivitis 1% - 6% x x x x x x x x x x x x x x x x x x
Depression 1% - 5% x x x x x x x x x x x x x x x
Lethargy 1% - 10% x x x x x x x x x x x x x x x x
Nausea 1% - 53% x x x x x x x x x x x x x x x x x x x
Pleural effusion 1% - 7% x x x x x x x
Urinary tract infection 1% - 4% x x x x x x x x x x x x x x x
Vomiting 1% - 37% x x x x x x x x x x x x x x x x x x x
Lacrimation increased 1% - 7% x x x x x x x x x x x x x x x x
Gastrointestinal motility disorder 1% - 10% x x x x x x x x
Phosphatase alkaline increased 0% - 29% x x x x
Abnormal vision 2% - 5% x x x x x x x x x
Erythema 1% - 6% x x x x x x x x x x x x x
Anaemia 1% - 83% x x x x x x x x x x x x x x x x x x x
Anorexia 1% - 23% x x x x x x x x x x x x x x x x x x x
Arthralgia 1% - 24% x x x x x x x x x x x x x x x x x
Back pain 1% - 11% x x x x x x x x x x x x x x x x x
Epistaxis 0.1% - 6% x x x x x x x x x x x x x x x x x x
Infarction 3% x x x x x x x x
Venous thrombosis 1% - 8% x x x x x x x x x
Decreased appetite 1% - 31% x x x x x x x x x x x x x x x x x
Rhinorrhoea 3% x x x x x x x x x x x x x x x
Abdominal pain upper 1% - 7% x x x x x x x x x x x x
Neutropenic sepsis 2.4% x x x x x x x x
Calcium low 0.8% - 13.2% x x x x x x x
Nail discolouration 1% - 4% x x x x x x x x
Dehydration 1% - 8% x x x x x x x x x x x x x x x x x x x
Dyspnoea 1% - 16% x x x x x x x x x x x x x x x x x x x
Body temperature increased 1% - 34% x x x x x x x x x x x x x x x x x x x
Pain in extremity 1% - 13% x x x x x x x x x x x x x x x x x x x
Thrombocytopenia 1% - 24% x x x x x x x x x x x x x x x x x
Bone pain 0.1% - 10% x x x x x x x x x x x x x x x x
Throat sore 1% - 11% x x x x x x x x x x x x x x x x x
Ileus 0.3% - 6% x x x x x x x x x
Oedema 1% - 34% x x x x x x x x x x x x x x x x x
Hypersensitivity 1.2% - 2% x x x x x x x x x x x x x x x x
Syncope 1.2% x x x x x x x x x x x x x x
Haemoglobin decreased 0.1% - 41.4% x x x x x x x
Ca++ increased 0.4% - 5.2% x x x x x x x
Chest pain 0.2% - 6% x x x x x x x x x x x x x x x x x x
Cough 0.1% - 22% x x x x x x x x x x x x x x x x x
Gastrointestinal haemorrhage 1% - 6% x x x x x x x x x x x x x x x x x x
Laryngitis 1% x x x x x x x x x x
Lymphoedema 0.1% - 5% x x x x x x x x x x
Pain 0.1% - 12% x x x x x x x x x x x x x x x x x x
Paraesthesia 1% - 21% x x x x x x x x x x x x x x x x x x x
Idiopathic thrombocytopenic purpura 1% x x x x x x x x x x x
Onycholysis 1% - 5% x x x x x x x x
Platelet count decreased 0.5% - 20.4% x x x x x x x
Orthostatic hypotension 0.8% x x x x x x x x
Diarrhoea haemorrhagic 0.8% x x x x x x x x
Ageusia 0.8% x x x x x x x x
Hypotension 0.2% - 1.2% x x x x x x x x x x x x x x x x
Renal impairment 0.6% x x
Oral candidiasis 1% - 8% x x x x x x x x x x x x x x x x x
Hypoaesthesia 1% - 8% x x x x x x x x x x x x x x x x
Serum creatinine increased 0% - 13.8% x x x
Ataxia 0.4% - 0.5% x x x x x x x x x x x x x x x x x x
Cachexia 0.4% x x x x x x x x x
Coma hepatic 0.4% x x x x x x x x
Jaundice 0.4% x x x x x x x x x x x x x x x
Renal failure 0.4% x x x x x x x x
Supraventricular tachycardia 0.4% x x x x x x x x
Thrombophlebitis 0.4% x x x x x x x x x x x x x x x
Hepatic failure postmarketing, 0.4% x x x x x x x x x x x x x x x x x
Migraine 0.4% x x x x x x x x
Liver function test abnormal 0.4% x x x x x x x x x
Oesophageal ulcer 0.4% x x x x x x x
Polyneuropathy 0.4% x x x x x x x x
Hepatotoxicity 0.4% x x x x x x x x
Necrotizing enterocolitis 0.4% x x x x x x x x x
Prothrombin level decreased 0.4% x x x x x x x x
Sodium decreased 0.4% - 17.5% x x x
Sepsis 0.3% - 0.4% x x x x x x x x x x x x x x x x x x
Bronchopneumonia 0.2% - 0.4% x x x x x x x x x x
Potassium low 0.2% - 19.9% x x x
Asthma 0.2% x x x x x x x x x x x x x x
Bronchitis 0.2% x x x x x x x x x x
Pneumonia 0.2% x x x x x x x x x x
Pulmonary embolism 0.2% x x x x x x x x x x x x x x x
Loss of consciousness 0.2% x x x x x x x x x x
Radiation recall syndrome 0.2% x x x x x x x x x x x x x x x x x x
Arthritis 0.1% x x x x x x x x x
Ascites 0.1% x x x x x x x x x x x x x x x
Coagulopathy 0.1% x x x x x x x x x x
Confusional state 0.1% x x x x x x x x x x x x x x x x x x
Drug hypersensitivity 0.1% x x x x x x x x x
Fibrosis 0.1% x x x x x x x x x
Gastroenteritis 0.1% x x x x x x x x x x x x x x x x
Hepatitis 0.1% x x x x x x x x x x
Hypertension 0.1% x x x x x x x x x x x x x x x x x x
Hypertriglyceridaemia 0.1% x x x x x x x x x x x x x x x x
Myocarditis 0.1% x x x x x x x x x
Pancytopenia 0.1% x x x x x x x x x x x x x x x x x x
Gastric ulcer 0.1% x x x x x x x x x
Cerebrovascular accident 0.1% x x x x x x x x x x
Tachycardia 0.1% x x x x x x x x x x x x x x x x x
Encephalopathy 0.1% x x x x x x x x x x x x x x x x x x
Hepatitis cholestatic postmarketing, 0.1% x x x x x x x x x x x x x x x x x x
Bone marrow depression 0.1% x x x x x x x x x x x x x x x x x
Photosensitivity reaction 0.1% x x x x x x x x x x x x x x x x x
Hepatic fibrosis 0.1% x x x x x x x x x x
Respiratory distress 0.1% x x x x x x x x x x
Sweating increased 0.1% x x x x x x x x x x
Abdominal distension x x x x x x x x x x x x x x x
Congenital anomaly x
Amnesia x
Haemolytic anaemia x x x x x x
Angina pectoris x x x x x x x x x x
Angina unstable x x x x x x
Anxiety x x x x x x
Aphasia x x x x x x
Appetite disorder x x x x x x
Arrhythmia x x x x x x x x
Atrial fibrillation x x x x x x x x x x x x x x x x x
Balanoposthitis x
Mental disorder x x x x x x x x
Blister x x x x x x x
Breast disorder x x x x x x
Bronchospasm x x
Burning mouth syndrome x x x x x x
Candida infection x x x x x x x x
Cellulitis x x x x x x x
Transient ischaemic attack x
Neck pain x
Colitis x x x x x x x x x
Infection x x x x x x x x x x x x x x x x x x
Connective tissue disorder x x x x x x x x
Contusion x x x x x x x
Corneal disorder x x x x x
Deafness x
Sudden death x x x x x x x x
Libido decreased x x x x x x x
Dysphagia x x x x x x x x x x x x x x x
Dermatitis exfoliative x
Diabetes mellitus x x x x x x x
Diplopia x x x x x x
Duodenitis x x x
Dysarthria x x x x x x x x x x x
Dysuria x x x x x x x
Ear pain x x x x x x x
Ecchymosis x x
Oedema due to cardiac disease x x
Embolism x x x x x x x x x
Enteritis x x x x x x
Toxic epidermal necrolysis x
Palmar erythema x x x x x x x
Oesophagitis x x x x x x x x x x
Eye disorder x x x x x x x x x x x x
Facial pain x x x x x x
Facial paralysis x
Liver fatty x
Flatulence x x x x x x x x
Localised infection x
Food allergy x
Gastritis x x x x x x x x x
Gastrooesophageal reflux disease x x x x x x
Gastrointestinal disorder x x x x x x x x x x x x
Cardiac arrest x x
Cardiac disorder x x x x x x x x
Cardiac failure x x x x x x x x x x
Haematemesis x
Haematoma x
Haematuria x x x x x x x
Haemoptysis x x x x x x x x x x x x x x x
Haemorrhage x x x x x x x x x
Haemorrhoids x
Hepatomegaly x
Herpes simplex x
Herpes zoster x x x x x x x
Herpes virus infection x x x x x x
Hiccups x x x x x x x
Hirsutism x
Hoarseness x x x x x x x x x
Hydronephrosis x x x x x x x
Hyperaesthesia x
Hyperhidrosis x x x x x x
Hypertensive crisis x x x x x x
Hypocalcaemia x x x x x x x
Hypokalaemia x x x x x x x x x x x x x x x x x
Hyponatraemia x x x x x x
Hypothyroidism x
Immune system disorder x x x x x x
Inflammation x x
Influenza x x x x x x x
Intertrigo x
Intestinal obstruction x x x x x x x x
Irritability x x x x x x x x x
Keratitis x x x x x
Keratoconjunctivitis x x x x x x x x x
Actinic keratosis x
Renal failure acute x
Leg ulcer x
Lipoma x x x x x x x
Cutaneous lupus erythematosus x x x x x
Mediastinal disorder x x x x x x x x x x
Melaena x
Metrorrhagia x
Fungal infection x x x x x x x x x x x x x x x
Myocardial infarction x x
Myoclonus x
Nasopharyngitis x x x x x x
Neoplasm x x x x x x x
Nervous system disorder x x x x x x x x x x x x
Neuralgia x x x x x x x
Night sweats x x x x x x
Nocturia x x x x x x x x x
Otitis media x
Palpitations x x x x x x
Ileus paralytic x
Pericardial effusion x x x x x x x x x
Petechiae x x x x x x
Pharyngitis x x x x x x x
Phlebitis x x x x x x x x x x x x x x x
Pleural disorder x
Pneumothorax x x x x x x x
Polyuria x
Postoperative complications NOS x
Proteinuria x x x x x x
Prurigo x
Pruritus genital x
Purpura x x x x x x
Rales x
Rectal disorder x
Proctalgia x x x x x x x x x
Rhinitis x x x x x x x
Rosacea x
Shivering x
Skin lesion x
Skin ulcer x x x x x x x x x x x x x x x
Sneezing x
Somatoform disorder x
Muscle spasms x x x x x x
Stevens-Johnson syndrome x
Superinfection x
Swelling x x
Sinus tachycardia x x x x x x
Thirst x x x x x x x x x
Thrombosis x x x x x x x x
Tinnitus x x x x x x
Tongue disorder x
Tonsillitis x x x x x x
Torsade de pointes x x x x x
Tremor x x x x x x x x x x x x x x x
Trismus x x x x x x
Ulcer x x x x
Upper gastrointestinal haemorrhage x x x x x x
Upper respiratory tract infection x x x x x x x x
Urinary incontinence x x x x x x x
Urinary tract disorder x x x x x x x
Urticaria x x x x x x x
Varicose vein x
Angiopathy x x x x x x x x
Ventricular fibrillation x x x x x x
Vertigo x x x x x x x x x x x x x x x x x
Disorder sight x x x x x x
Weight increased x x x x x x x x x
Urinary retention x
Ulcer foot x
Chills x x x x x x
Atrial arrhythmia x x
Vasospasm x x x x x x
Orthopnoea x
Oedema peripheral x x x x x x x
Cataract x
Hepatic function abnormal x x x x x x x
Panic attack x x x x x x
Lower respiratory tract infection x x x x x x x
Mouth ulceration x x x x x x x x
Deep vein thrombosis x x x x x x x x
Creatinine renal clearance decreased x x x x x x
Swelling face x x x x x x
Ventricular extrasystoles x x x x x x x x x x x x x x x x
Gastrointestinal perforation x
Hypomagnesaemia x x x x x x x x x x x x x x x
Injection site reaction x x x x x x
Myocardial ischaemia x x x x x x x x
Muscular weakness x x x x x x x x x x x x x x x
Eye pain x x x x x x
Injection site pain x x x x x x
Prothrombin level increased x x x x x x
Alanine aminotransferase increased x
Dry skin x x x x x x x x
WBC abnormal NOS x x
Sensory disturbance x x x x x x x x
Joint swelling x x x x x x
Calcaneal spur x
Joint stiffness x
Malnutrition x x x x x x x x x x x x x
Skin hyperpigmentation x x x x x x x
Unspecified disorder of skin and subcutaneous tissue x x x x x x x x x x x
Scab x
Odynophagia x
Rash macular x x x x x x
Skin fissures x x
Injection site infection x
Oral pain x x x x x x x
Malaise x x x x x x x
Dyspnoea exertional x x x x x x
Chest tightness x
Increased appetite x x
Abdominal discomfort x x x x x x
Abdominal pain lower x x x x x x
Memory impairment x x x x x x
Visual acuity reduced x x x x x x
Nail changes x
Neurotoxicity x x x x x x
Blood creatinine increased x x x x x
Pain in jaw x x x x x x x x
Mucosal ulceration x x
Vaginal pain x
Skin exfoliation x x x x x x x
Oesophageal candidiasis x
Edema of lower extremities x x x x x x x x x
Neck oedema of x
Personality change x
Punctate keratitis x x x x
Nasal ulcer x
Rectal haemorrhage x x x x x x x
Incisional hernia x
Hepatobiliary disease x x x x x x x x
Fluid retention x
Peroneal nerve palsy x
Peripheral coldness x x x x x x
Walking disability x x x x x x x x x
Dry eye x x x x x x
Mucosal inflammation x x x x x x x x
Extrasystoles x x x x x x x x x
Oral herpes x x x x x x
Gastrointestinal candidiasis x
Vision blurred x x x x x x
Depressed mood x x x x x x
Chest mass NOS x x x x x x x x x
Photosensitivity x x
Premenstrual tension x
Dysaesthesia x x x x x x x x
Nipple disorder x
Cardiac pain x x
Rigors x x x x x x x x
Bradycardia x x x x x x x x x x x x x x x
Neuropathy x x
Metastases to liver x x
Blood pressure increased x
Tooth abscess x x x x x x
Toxic dilatation of intestine x x x x x x x x x
Sudden death, cause unknown x
Localized exfoliation x x
Coordination abnormal x x x x x x x x x x x
Paraesthesia oral x x x x x
Hypoaesthesia oral x x x x x x
Hepatic pain x
Urine color abnormal x
Ear feels clogged x
Face oedema x
Depressed level of consciousness x
Loss of confidence x
Wound discharge increased x
Localised skin reaction x
Pigmentation disorder x x x x x x x
Balance disorder x x x x x x x x x x x x x x x x
Hot flush x x x x x x x x x x x x x x x
Infestation NOS x x x x x x x x x
Blood and lymphatic system disorders x x x x x x x x x x x x
Ear and labyrinth disorders x x x x x x
Sleep disorder x x x x x x
Pre-menstrual tension syndrome x
Redness of face x
Thromboembolic event x
Pharyngolaryngeal pain x x x x x x
Hyperkeratosis x
Cardiomyopathy x x x x x x x x x x
Musculoskeletal stiffness x x x x x x
Infusion related reaction x x x x x x
Dysphasia x x x x x x x x x
Infusion site pain x x x x x x
Temperature intolerance x x x x x x x x
Gastrointestinal toxicity x
Mental disability x
Blood in stool x x x x x x
Dysaesthesia pharynx x x x x x x x x
Scratch x
Hearing impaired x x x x x x
Dysphonia x x x x x x x x
Radiation recall reaction (dermatologic) x
Acute overdose x x
Tingling sensation x
Gastrointestinal tract irritation x x
Vaginal haemorrhage x x x x x x
Visual impairment x x x x x x
Food intolerance x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Capecitabine

Side effects:51
Source:BC Cancer

capecitabine / XELODA

Side effects:135
Source:medicines.org.au

capecitabine / capecitabine

Side effects:240
Source:EMA

capecitabine / capecitabine

Side effects:241
Source:EMA

capecitabine / capecitabine

Side effects:242
Source:EMA

capecitabine / capecitabine

Side effects:244
Source:EMA

capecitabine / capecitabine

Side effects:244
Source:EMA

capecitabine / capecitabine

Side effects:247
Source:EMA

/ Xeloda capecitabine Tablets

Side effects:82
Source:FDA

/ Xeloda capecitabine Tablets

Side effects:127
Source:FDA

Capecitabine / Xeloda

Side effects:159
Source:FDA

Capecitabine / Xeloda

Side effects:160
Source:FDA

capecitabine / XELODA

Side effects:161
Source:FDA

CAPECITABINE / XELODA

Side effects:172
Source:FDA

capecitabine

Side effects:174
Source:FDA Structured Product Label

capecitabine

Side effects:175
Source:FDA Structured Product Label

CAPECITABINE

Side effects:175
Source:FDA Structured Product Label

CAPECITABINE / XELODA 150MG

Side effects:280
Source:Health Canada

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label