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Bexarotene

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01XX25

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7
Malnutrition 78.6% - 79.2% x x x x
Pruritus very common, 18% - 40% x x x x x x x
Hypercholesterolaemia very common, 0% - 62.3% x x x x x
Pain very common, 12% - 40% x x x x
Hypothyroidism very common, 0% - 52.8% x x x x x
Rash very common, 0% - 78% x x x x x x x
Headache very common, 0% - 41.5% x x x x x x x
Asthenia 0% - 45.3% x x x x x x x
Skin disorder common, 18% - 26% x x x
Leukopenia very common, 0% - 47.2% x x x x x x x
Nausea 7.55% - 16% x x x x
Infection common, 0% - 22.6% x x x x x x x
Dermatitis contact 8% - 14% x x x
Dry skin 9.43% - 11% x x x x
Hyperlipidaemia very common, 0% - 79.2% x x x x x x x
Chills 9.52% - 13.2% x x x x
Cataract uncommon, 19% x x
Dermatitis exfoliative very common, 0% - 28.3% x x x x x x x
Hypochromic anaemia 3.57% - 13.2% x x x
Abdominal pain common, 3.77% - 11% x x x x x
Diarrhoea 1% - 41.5% x x x x
Lactic dehydrogenase activity increased common, 7.14% - 13.2% x x x x
Anaemia 5.95% - 24.5% x x x x
Paraesthesia 6% x x x
Oedema peripheral common, 0% - 13.1% x x x x x x x
Tachycardia uncommon, 10% x x x x x
Albuminuria 10% x x x x
Angina pectoris 10% x x x x
Arthralgia common, 10% x x x x x
Bronchitis 10% x x x x
Cheilitis 10% x x x x
Chest pain 10% x x x x x
Colitis 10% x x x x
Confusional state 10% x x x x x
Conjunctivitis 10% x x x x
Constipation common, 10% x x x x x
Cough 10% x
Deafness common x
Dizziness common, 10% x x x x x
Dyspepsia 10% x x x x x
Dyspnoea 10% x x x x x
Dysuria 10% x x x x
Ear pain 10% x x x x
Eosinophilia 10% x x x x
Eye disorder common x
Body temperature increased 4.76% - 17% x x x x
Flatulence common, 10% x x x x x
Gastroenteritis 10% x x x x
Gingivitis 10% x x x x x
Haematuria 10% x x x x x
Haemoptysis 10% x x x x x
Hypersensitivity common x x x x x
Hypoaesthesia common, 10% x x x x x
Hypoproteinaemia common, 10% x x x x x
Arthropathy 10% x x x x x
Keratitis 10% x x x x
Breast pain 10% x x x x
Melaena 10% x x x x x
Otitis externa 10% x x x x
Pleural effusion 10% x x x x
Pulmonary oedema 10% x x x x
Rhinitis 10% x x x x x
Skin nodule common, 10% x x x x x
Skin ulcer common, 10% x x x x x
Cerebrovascular accident 10% x x x x
Syncope 10% x x x x
Thrombocytopenia 10% x x x x
Thyroid disorder common x
Urinary incontinence 10% x x x x
Urinary tract infection 10% x x x x
Weight increased common, 10% x x x x x
Weight decreased 10% x x x x x
Dry mouth 10% x x x x
Micturition urgency 10% x x x x
Coagulation time prolonged 10% x x x x
Creatinine increased common x x x x
Skin hypertrophy common x
Liver function test abnormal common x
Bone pain common, 10% x x x x x
Pseudolymphoma common x
Myalgia common, 10% x x x x x
Cardiac failure right 10% x x x x
Sepsis 10% x x x x
Dry eye common, 10% x x x x x
Acne common x
Insomnia common, 4.76% - 11.3% x x x x x
Myasthenia 10% x x x x
Alopecia 3.57% - 11.3% x x x x
Influenza 3.57% - 13.2% x x x x x
Pneumonia 2% - 3.8% x x x x x
Vomiting common, 0% - 13.2% x x x x x
Ataxia uncommon, 10% x x x x x
Blepharitis uncommon, 10% x x x x x
Cellulitis uncommon, 10% x x x x x
Hyperaesthesia uncommon, 10% x x x x x
Hypertension uncommon, 10% x x x x x
Lymphocytosis uncommon, 10% x x x x x
Scotoma uncommon, 10% x x x x x
Agitation uncommon, 10% x x x x x
Corneal lesion uncommon, 10% x x x x x
Neuropathy uncommon, 10% x x x x x
Thrombocytosis uncommon, 10% x x x x x
Pharyngitis 0% - 6% x x x x x x x
Sweating common, 0% - 6% x x x
Lymphadenopathy common, 0% - 6% x x x
Anorexia 0% - 22.6% x x x x
Back pain 2% - 11.3% x x x x
Bacterial infection 0% - 13.2% x x x
Aspartate aminotransferase increased common, 0% - 3.77% x x x x
Alanine aminotransferase increased common, 0% - 3.77% x x x x
Coagulopathy uncommon x
Ear disorder uncommon x
Gout uncommon x
Blood disorder uncommon x
Haemorrhage uncommon x x x x x
Herpes simplex uncommon x
Hyperthyroidism uncommon x
Neoplasm uncommon x
Purpura uncommon x
Varicose vein uncommon x
Vertigo uncommon x
Hepatic failure uncommon x x x x
Rash pustular uncommon x x x x
High density lipoprotein decreased uncommon x x x x
Kidney function abnormal uncommon x x x x
Laboratory test abnormal uncommon x
Infection parasitic uncommon x
Pancreatitis acute x x x x
Anxiety x
Arrhythmia x x
Arthritis x
Oral candidiasis x
Carcinoma x
Cholecystitis x
Connective tissue disorder x
Libido decreased x
Dysphagia x
Dehydration x
Dermatitis x
Dysgeusia x
Ecchymosis x
Oedema 0% - 10% x x
Endocrine disorder x
Epistaxis x
Eructation x
Excoriation x
Fasting x
Fatigue x x x x
Furunculosis x
Gastrointestinal disorder x
Cardiac disorder x
Cardiac failure congestive x
Subdural haematoma x x x x
Herpes zoster x
Hyperbilirubinaemia 0% - 3.77% x x x x
Hypercalcaemia x
Hyperglycaemia 0% - 5.7% x x x x
Hyperkalaemia 0% - 1.9% x x x
Hypernatraemia 0% - 1.2% x x x
Hypertriglyceridaemia x x x x x
Hypocalcaemia 0% - 1.2% x x x
Hypokalaemia x
Hyponatraemia 0% - 9.4% x x x x
Jaundice x
Jaundice cholestatic x
Lacrimal disorder x
Laryngospasm x
Cramps of lower extremities x
Lethargy x x x x
Lung disorder x
Hypertonia x
Nervous system disorder x
Nervousness x
Neuritis x
Neutropenia x x x x
Night blindness x
Nocturia x
Nystagmus x
Pallor x
Palpitations x
Pancreatitis 0% - 5.66% x x x x
Pelvic pain x
Petechiae x
Pleural disorder x
Polyuria x
Psoriasis x
Seborrhoeic dermatitis x
Sinusitis x
Muscle spasms x x x x
Stomatitis x
Thirst x
Tinnitus x
Erythema x
Urinary tract disorder x
Angiopathy x
Viral infection x
Urinary retention x
Peripheral vascular disorder x
Body odor x
Stupor x
Mood swings x
Mouth ulceration x
Migraine x
Amylase increased x x x x
Generalised oedema x
Hypocholesterolaemia x
Hypomagnesaemia x
Hepatocellular injury x
Bone marrow depression x
Eye pain x
Circumoral paresthesia x
Phosphatase alkaline increased x
Thromboplastin decreased x
WBC abnormal NOS 0% - 6% x x x
Vascular anomaly x
Abnormal faeces x
Dermatitis irritant contact x
Photosensitivity reaction x
Eruption lichenoid x
Unspecified disorder of skin and subcutaneous tissue x
Fatal outcomes x
Malaise x
Increased appetite x
Rectal tenesmus x
Thinking abnormal x
Urine abnormality x
Rash bullous x x x
Erectile dysfunction x
Redness x
Hypolipidaemia x
Enlargement abdomen x
Rash maculo-papular 0% - 6% x x x
Face oedema x
Hypovolaemia x
Lipase increased x
Cough increased 0% - 6% x x x x x x
Gait disturbance x
Hyperuricaemia x
Febrile neutropenia x
Blood and lymphatic system disorders x
Ear and labyrinth disorders x
Rash papular x x x
Breast enlargement x
Somnolence x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

bexarotene

Side effects:20
Source:FDA Structured Product Label

BEXAROTENE / TARGRETIN

Side effects:25
Source:FDA

Bexarotene

Side effects:103
Source:BC Cancer

BEXAROTENE / TARGRETIN

Side effects:118
Source:FDA

BEXAROTENE

Side effects:118
Source:FDA Structured Product Label

BEXAROTENE / TARGRETIN

Side effects:118
Source:FDA

bexarotene / bexarotene

Side effects:186
Source:EMA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label