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Focal segmental glomerulosclerosis

Definition: A clinicopathological syndrome or diagnostic term for a type of glomerular injury that has multiple causes, primary or secondary. Clinical features include PROTEINURIA, reduced GLOMERULAR FILTRATION RATE, and EDEMA. Kidney biopsy initially indicates focal segmental glomerular consolidation (hyalinosis) or scarring which can progress to globally sclerotic glomeruli leading to eventual KIDNEY FAILURE.

Synonyms (terms occurring on more labels are shown first): focal segmental glomerulosclerosis, Focal segmental glomerulo- sclerosis

More information: PubMed search and possibly Wikipedia

Show drugs for which this side effect directly occurs

Drugs with this side effect as MedDRA Preferred Term

  • pamidronate
    • Focal segmental glomerulosclerosis: postmarketing, rare
  • rapamycin
    • Focal segmental glomerulosclerosis: postmarketing