Boceprevir
  
Side effects 
	
		
Options: 
			
			Show MedDRA Preferred Terms
		
	
	
| Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 
| Fatigue | very common, 50% - 59% |  | x | x | x | x | 
| Nausea | very common, 38% - 42% |  | x | x | x | x | 
| Headache | very common, 48% |  | x | x | x | x | 
| Chills | very common, 29% - 30% |  | x | x | x | x | 
| Influenza like illness | very common, 25% |  |  | x | x | x | 
| Insomnia | very common, 20% - 34% |  | x | x | x | x | 
| Body temperature increased | very common, 21% |  |  | x | x | x | 
| Anaemia | very common, 20% - 30% |  | x | x | x | x | 
| Myalgia | very common, 24% |  |  | x | x | x | 
| Pruritus | very common, 18% |  |  | x | x | x | 
| Alopecia | very common, 16% - 27% |  | x | x | x | x | 
| Asthenia | very common, 16% - 18% |  | x | x | x | x | 
| Decreased appetite | very common, 16% - 24% |  | x | x | x | x | 
| Arthralgia | very common, 14% - 19% |  | x | x | x | x | 
| Dyspnoea | very common, 16% |  |  | x | x | x | 
| Cough | very common, 15% |  |  | x | x | x | 
| Diarrhoea | very common, 15% - 22% |  | x | x | x | x | 
| Depression | 15% |  |  | x | x |  | 
| Irritability | very common, 13% - 23% |  | x | x | x | x | 
| Dizziness | very common, 10% - 16% |  | x | x | x | x | 
| Weight decreased | very common, 9% |  |  | x | x | x | 
| Dry skin | very common, 8% - 18% |  | x | x | x | x | 
| Dysgeusia | very common, 11% - 16% |  | x | x | x | x | 
| Anxiety | very common, 6% |  |  | x | x | x | 
| Rash | very common, 5% - 19% |  | x | x | x | x | 
| Neutropenia | very common, 10% - 19% |  | x | x | x | x | 
| Dry mouth | very common, 8% - 10% |  | x | x | x | x | 
| Vomiting | very common, 8% - 13% |  | x | x | x | x | 
| Abdominal distension | common |  |  |  |  | x | 
| Abdominal pain | common |  |  |  |  | x | 
| Amnesia | common |  |  |  |  | x | 
| Back pain | common |  |  |  |  | x | 
| Bronchitis | common |  |  |  |  | x | 
| Cellulitis | common |  |  |  |  | x | 
| Neck pain | common |  |  |  |  | x | 
| Cheilitis | common |  |  |  |  | x | 
| Chest pain | common |  |  |  |  | x | 
| Constipation | common |  |  |  |  | x | 
| Dehydration | common |  |  |  |  | x | 
| Dermatitis | common |  |  |  |  | x | 
| Dyspepsia | common |  |  |  |  | x | 
| Eczema | common |  |  |  |  | x | 
| Epistaxis | common |  |  |  |  | x | 
| Flatulence | common |  |  |  |  | x | 
| Gastrooesophageal reflux disease | common |  |  |  |  | x | 
| Glossodynia | common |  |  |  |  | x | 
| Goitre | common |  |  |  |  | x | 
| Haemorrhoids | common |  |  |  |  | x | 
| Herpes simplex | common |  |  |  |  | x | 
| Hyperglycaemia | common |  |  |  |  | x | 
| Hyperhidrosis | common |  |  |  |  | x | 
| Hypertension | common |  |  |  |  | x | 
| Hypertriglyceridaemia | common |  |  |  |  | x | 
| Hypoaesthesia | common |  |  |  |  | x | 
| Hypotension | common |  |  |  |  | x | 
| Hypothyroidism | common |  |  |  |  | x | 
| Influenza | common |  |  |  |  | x | 
| Leukopenia | common |  |  |  |  | x | 
| Nasal congestion | common |  |  |  |  | x | 
| Night sweats | common |  |  |  |  | x | 
| Pain in extremity | common |  |  |  |  | x | 
| Palpitations | common |  |  |  |  | x | 
| Paraesthesia | common |  |  |  |  | x | 
| Prurigo | common |  |  |  |  | x | 
| Psoriasis | common |  |  |  |  | x | 
| Sinusitis | common |  |  |  |  | x | 
| Skin lesion | common |  |  |  |  | x | 
| Muscle spasms | common |  |  |  |  | x | 
| Aphthous stomatitis | common |  |  |  |  | x | 
| Syncope | common |  |  |  |  | x | 
| Tinnitus | common |  |  |  |  | x | 
| Tooth disorder | common |  |  |  |  | x | 
| Erythema | common |  |  |  |  | x | 
| Pollakiuria | common |  |  |  |  | x | 
| Vertigo | common |  |  |  |  | x | 
| Wheezing | common |  |  |  |  | x | 
| Mood swings | common |  |  |  |  | x | 
| Oedema peripheral | common |  |  |  |  | x | 
| Migraine | common |  |  |  |  | x | 
| Muscular weakness | common |  |  |  |  | x | 
| Sinus congestion | common |  |  |  |  | x | 
| Rash macular | common |  |  |  |  | x | 
| Oral pain | common |  |  |  |  | x | 
| Malaise | common |  |  |  |  | x | 
| Dyspnoea exertional | 5% - 8% |  | x | x | x |  | 
| Abdominal discomfort | common |  |  |  |  | x | 
| Abdominal pain upper | common |  |  |  |  | x | 
| Disturbance in attention | common |  |  |  |  | x | 
| Affect lability | common |  |  |  |  | x | 
| Memory impairment | common |  |  |  |  | x | 
| Rash erythematous | common |  |  |  |  | x | 
| Chest discomfort | common |  |  |  |  | x | 
| Retinal exudates | common |  |  |  |  | x | 
| Erectile dysfunction | common |  |  |  |  | x | 
| Dry eye | common |  |  |  |  | x | 
| Vision blurred | common |  |  |  |  | x | 
| Rash maculo-papular | common |  |  |  |  | x | 
| Feeling of body temperature change | common |  |  |  |  | x | 
| Hyperuricaemia | common |  |  |  |  | x | 
| Sleep disorder | common |  |  |  |  | x | 
| Mucosal dryness | common |  |  |  |  | x | 
| Libido disorder | common |  |  |  |  | x | 
| Oral fungal infection | common |  |  |  |  | x | 
| Respiratory tract congestion | common |  |  |  |  | x | 
| Parosmia | common |  |  |  |  | x | 
| Rash papular | common |  |  |  |  | x | 
| Anorectal discomfort | common |  |  |  |  | x | 
| Oropharyngeal pain | common |  |  |  |  | x | 
| Visual impairment | common |  |  |  |  | x | 
| Pain | common, 4% |  |  | x | x | x | 
| Agitation | uncommon, common |  |  |  |  | x | 
| Agranulocytosis | postmarketing, common |  | x |  |  | x | 
| Pancytopenia | postmarketing, common |  | x |  |  | x | 
| Stomatitis | postmarketing, common |  | x |  | x | x | 
| Thrombocytopenia | postmarketing, common |  | x |  |  | x | 
| Mouth ulceration | postmarketing, common |  | x |  | x | x | 
| Aggression | uncommon |  |  |  |  | x | 
| Amenorrhoea | uncommon |  |  |  |  | x | 
| Anger | uncommon |  |  |  |  | x | 
| Appetite disorder | uncommon |  |  |  |  | x | 
| Arrhythmia | uncommon |  |  |  |  | x | 
| Arthritis | uncommon |  |  |  |  | x | 
| Candida infection | uncommon |  |  |  |  | x | 
| Cardiovascular disorder | uncommon |  |  |  |  | x | 
| Pleuritic pain | uncommon |  |  |  |  | x | 
| Cognitive disorder | uncommon |  |  |  |  | x | 
| Colitis | uncommon |  |  |  |  | x | 
| Confusional state | uncommon |  |  |  |  | x | 
| Conjunctival haemorrhage | uncommon |  |  |  |  | x | 
| Conjunctivitis | uncommon |  |  |  |  | x | 
| Deafness | uncommon |  |  |  |  | x | 
| Dysphagia | uncommon |  |  |  |  | x | 
| Sensitivity of teeth | uncommon |  |  |  |  | x | 
| Fungal skin infection | uncommon |  |  |  |  | x | 
| Diabetes mellitus | uncommon |  |  |  |  | x | 
| Dysuria | uncommon |  |  |  |  | x | 
| Flushing | uncommon |  |  |  |  | x | 
| Gastritis | uncommon |  |  |  |  | x | 
| Gastroenteritis | uncommon |  |  |  |  | x | 
| Gingival bleeding | uncommon |  |  |  |  | x | 
| Gingivitis | uncommon |  |  |  |  | x | 
| Glossitis | uncommon |  |  |  |  | x | 
| Gout | uncommon |  |  |  |  | x | 
| Cardiac murmur | uncommon |  |  |  |  | x | 
| Haemorrhagic disorder | uncommon |  |  |  |  | x | 
| Hyperbilirubinaemia | uncommon |  |  |  |  | x | 
| Hypercalcaemia | uncommon |  |  |  |  | x | 
| Hyperaesthesia | uncommon |  |  |  |  | x | 
| Hyperthyroidism | uncommon |  |  |  |  | x | 
| Hypokalaemia | uncommon |  |  |  |  | x | 
| Eye pruritus | uncommon |  |  |  |  | x | 
| Lethargy | uncommon |  |  |  |  | x | 
| Lymphopenia | uncommon |  |  |  |  | x | 
| Menorrhagia | uncommon |  |  |  |  | x | 
| Metrorrhagia | uncommon |  |  |  |  | x | 
| Musculoskeletal pain | uncommon |  |  |  |  | x | 
| Nasopharyngitis | uncommon |  |  |  |  | x | 
| Neuralgia | uncommon |  |  |  |  | x | 
| Nocturia | uncommon |  |  |  |  | x | 
| Pallor | uncommon |  |  |  |  | x | 
| Pancreatitis | uncommon |  |  |  |  | x | 
| Neuropathy peripheral | uncommon |  |  |  |  | x | 
| Pharyngitis | uncommon |  |  |  |  | x | 
| Anal pruritus | uncommon |  |  |  |  | x | 
| Pulmonary embolism | uncommon |  |  |  |  | x | 
| Proctalgia | uncommon |  |  |  |  | x | 
| Respiratory tract infection | uncommon |  |  |  |  | x | 
| Retinal disorder | uncommon |  |  |  |  | x | 
| Rhinitis | uncommon |  |  |  |  | x | 
| Salivary hypersecretion | uncommon |  |  |  |  | x | 
| Skin infection | uncommon |  |  |  |  | x | 
| Skin ulcer | uncommon |  |  |  |  | x | 
| Staphylococcal infection | uncommon |  |  |  |  | x | 
| Tachycardia | uncommon |  |  |  |  | x | 
| Onychomycosis | uncommon |  |  |  |  | x | 
| Loss of consciousness | uncommon |  |  |  |  | x | 
| Urinary tract infection | uncommon |  |  |  |  | x | 
| Apathy | uncommon |  |  |  |  | x | 
| Photophobia | uncommon |  |  |  |  | x | 
| Panic attack | uncommon |  |  |  |  | x | 
| Deep vein thrombosis | uncommon |  |  |  |  | x | 
| Tongue discolouration | uncommon |  |  |  |  | x | 
| Impaired healing | uncommon |  |  |  |  | x | 
| Bone pain | uncommon |  |  |  |  | x | 
| Eye pain | uncommon |  |  |  |  | x | 
| Joint swelling | uncommon |  |  |  |  | x | 
| Lacrimation increased | uncommon |  |  |  |  | x | 
| Ocular hyperaemia | uncommon |  |  |  |  | x | 
| Eyelid oedema | uncommon |  |  |  |  | x | 
| Retinal ischaemia | uncommon |  |  |  |  | x | 
| Photosensitivity reaction | uncommon |  |  |  |  | x | 
| Odynophagia | uncommon |  |  |  |  | x | 
| Abdominal pain lower | uncommon |  |  |  |  | x | 
| Abnormal behaviour | uncommon |  |  |  |  | x | 
| Dry throat | uncommon |  |  |  |  | x | 
| Faeces discoloured | uncommon |  |  |  |  | x | 
| Tongue ulceration | uncommon |  |  |  |  | x | 
| Gingival pain | uncommon |  |  |  |  | x | 
| Rectal haemorrhage | uncommon |  |  |  |  | x | 
| Eye swelling | uncommon |  |  |  |  | x | 
| Peripheral coldness | uncommon |  |  |  |  | x | 
| Suicidal ideation | uncommon |  |  |  |  | x | 
| Homicidal ideation | uncommon |  |  |  |  | x | 
| Musculoskeletal chest pain | uncommon |  |  |  |  | x | 
| Non-cardiac chest pain | uncommon |  |  |  |  | x | 
| Lymphadenopathy | uncommon |  |  |  |  | x | 
| Abnormal sensation in eye | uncommon |  |  |  |  | x | 
| Lip dry | uncommon |  |  |  |  | x | 
| Ear infection | uncommon |  |  |  |  | x | 
| Presyncope | uncommon |  |  |  |  | x | 
| Substance abuse | uncommon |  |  |  |  | x | 
| Mental status changes | uncommon |  |  |  |  | x | 
| Ear discomfort | uncommon |  |  |  |  | x | 
| Mental disability | uncommon |  |  |  |  | x | 
| Increased upper airway secretion | uncommon |  |  |  |  | x | 
| Hearing impaired | uncommon |  |  |  |  | x | 
| Feeling abnormal | uncommon |  |  |  |  | x | 
| Paranoia | uncommon |  |  |  |  | x | 
| Dysphonia | uncommon |  |  |  |  | x | 
| Oropharyngeal blistering | uncommon |  |  |  |  | x | 
| Pneumonia | postmarketing, uncommon |  | x |  |  | x | 
| Urticaria | postmarketing, uncommon |  | x |  | x | x | 
| Angioedema | postmarketing |  | x |  | x | x | 
| Atrial fibrillation | rare |  |  |  |  | x | 
| Bipolar disorder | rare |  |  |  |  | x | 
| Cholecystitis | rare |  |  |  |  | x | 
| Infection | postmarketing |  | x |  |  |  | 
| Dermatitis exfoliative | postmarketing |  | x |  | x |  | 
| Drug eruption | postmarketing |  | x |  | x | x | 
| Eosinophilia | postmarketing |  | x |  | x | x | 
| Epiglottitis | rare |  |  |  |  | x | 
| Gastrointestinal disorder | postmarketing |  | x | x | x | x | 
| Haemolysis | rare |  |  |  |  | x | 
| Nodule | rare |  |  |  |  | x | 
| Otitis media | rare |  |  |  |  | x | 
| Pancreatic insufficiency | rare |  |  |  |  | x | 
| Papilloedema | rare |  |  |  |  | x | 
| Pericardial effusion | rare |  |  |  |  | x | 
| Pericarditis | rare |  |  |  |  | x | 
| Sarcoidosis | rare |  |  |  |  | x | 
| Stevens-Johnson syndrome | postmarketing |  | x |  | x | x | 
| Suicide attempt | rare |  |  |  |  | x | 
| Thyroid neoplasm | rare |  |  |  |  | x | 
| Venous thrombosis | rare |  |  |  |  | x | 
| Encephalopathy | rare |  |  |  |  | x | 
| Orthopnoea | rare |  |  |  |  | x | 
| Acute myocardial infarction | rare |  |  |  |  | x | 
| Unspecified disorder of skin and subcutaneous tissue | postmarketing |  | x | x | x | x | 
| Hallucination, auditory | rare |  |  |  |  | x | 
| Hallucination, visual | rare |  |  |  |  | x | 
| Sepsis | postmarketing, rare |  | x |  |  | x | 
| Toxic skin eruption | postmarketing |  | x |  | x |  | 
| Psychiatric decompensation | rare |  |  |  |  | x | 
| Infestation NOS | postmarketing |  | x |  |  | x | 
| Blood and lymphatic system disorders | postmarketing |  | x | x | x | x | 
| Completed suicide | rare |  |  |  |  | x | 
| Porphyria non-acute | rare |  |  |  |  | x | 
| Cerebral ischaemia | rare |  |  |  |  | x | 
| Respiratory failure | rare |  |  |  |  | x | 
| Exfoliative rash | postmarketing |  | x |  | x |  | 
| Aspermia | rare |  |  |  |  | x | 
| Coronary artery disease | rare |  |  |  |  | x | 
| Pleural fibrosis | rare |  |  |  |  | x | 
| Mental disorder |  |  | x | x | x | x | 
| Breast disorder |  |  |  |  |  | x | 
| Connective tissue disorder |  |  | x | x | x | x | 
| Cyst |  |  |  |  |  | x | 
| Endocrine disorder |  |  |  |  |  | x | 
| Eye disorder |  |  |  |  |  | x | 
| Cardiac disorder |  |  |  |  |  | x | 
| Hypersensitivity |  |  | x |  | x |  | 
| Immune system disorder |  |  |  |  |  | x | 
| Mediastinal disorder |  |  | x | x | x | x | 
| Neoplasm |  |  |  |  |  | x | 
| Nervous system disorder |  |  | x | x | x | x | 
| Polyp |  |  |  |  |  | x | 
| Urinary tract disorder |  |  |  |  |  | x | 
| Angiopathy |  |  |  |  |  | x | 
| Injection site reaction |  |  |  | x | x | x | 
| Malnutrition |  |  | x | x | x | x | 
| Hepatobiliary disease |  |  |  |  |  | x | 
| Ear and labyrinth disorders |  |  |  |  |  | x | 
	 
 
  Indications
	Information about indications was extracted from the indications and usage sections of the labels.
	
 
	  
	  
		| Side effects: | 46 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 39 | 
|---|
		| Source: | Medsafe | 
|---|
		 
	  
	  
		| Side effects: | 50 | 
|---|
		| Source: | medicines.org.au | 
|---|
		 
	  
	  
		| Side effects: | 275 | 
|---|
		| Source: | EMA | 
|---|
		 
	  
  
 
  
	Color scheme:
	  
	  standard – alternative
	  
	
	
|  |  | 100% | 
|  |  | 75% | 
|  |  | 50% | 
|  |  | 10% | 
|  |  | frequent (1% to 100%) | 
|  |  | infrequent (0.1% to 1%) | 
|  |  | rare (<0.1%) | 
|  |  | postmarketing | 
|  |  | 0% | 
|  |  | no frequency information | 
|  |  | not found on label |