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Regorafenib

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: None found

Side effects

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Side effect Data for drug Placebo Labels
1 2
Anaemia 79% 66% x x
Aspartate aminotransferase increased 65% 46% x
Hypocalcaemia 59% 18% x x
Hypophosphataemia 57% 11% x
Lymphopenia 54% 34% x
Malnutrition 47% 28% x x
Decreased appetite 47% 28% x x
Proteinuria 33% - 60% 30% - 34% x x
Hyperbilirubinaemia 45% 17% x x
Alanine aminotransferase increased 45% 30% x
Thrombocytopenia 41% 17% x x
Mediastinal disorder 30% - 39% 6% - 9% x x
Dysphonia 30% - 39% 6% - 9% x x
Urinary tract disorder 33% 30% x x
Infection 31% - 32% 5% - 17% x x
Infestation NOS 31% - 32% 5% - 17% x x
Lipase increased 14% - 46% 5% - 19% x
Hyponatraemia 30% 22% x x
Hypokalaemia 26% 8% x x
Amylase increased 26% 17% x
International normalised ratio increased 24% 17% x
Weight decreased 14% - 32% 8% - 10% x x
Connective tissue disorder 14% 3% x x
Musculoskeletal stiffness 14% 3% x x
Headache 10% - 16% 7% - 9% x x
Nervous system disorder 10% - 16% 7% - 9% x x
Neutropenia 3% 0% x
Abdominal pain x
Alopecia x x
Asthenia x x
Squamous cell carcinoma x
Cyst x
Diarrhoea x x
Endocrine disorder x
Toxic epidermal necrolysis x
Erythema multiforme x
Rash x x
Fatigue x x
Body temperature increased x x
Fistula x
Gastroenteritis x
Gastrooesophageal reflux disease x
Gastrointestinal disorder x x
Cardiac disorder x
Haemorrhage x x
Hypertension x x
Hypertensive crisis x
Hypothyroidism x x
Infarction x
Keratoacanthoma x
Leukopenia x
Myocardial infarction x
Nail disorder x
Nausea x
Neoplasm x
Pain x x
Polyp x
Stevens-Johnson syndrome x
Stomatitis x
Taste disorders x
Tremor x
Angiopathy x x
Vomiting x
Dry mouth x
Gastrointestinal perforation x x
Hypomagnesaemia x
Myocardial ischaemia x x
Dry skin x
Liver injury x
Unspecified disorder of skin and subcutaneous tissue x x
Hepatotoxicity x
Hepatobiliary disease x x
Mucosal inflammation x x
Gastrointestinal fistula x
Hyperuricaemia x
Blood and lymphatic system disorders x x
Lipase abnormal x
Exfoliative rash x
Posterior reversible encephalopathy syndrome x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

REGORAFENIB

Side effects:52
Source:FDA Structured Product Label

regorafenib / regorafenib

Side effects:65
Source:EMA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label