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Temsirolimus

More information: STITCH, PubChem (stereo-specific compounds: 1, 2) and possibly Wikipedia

ATC Code: L01XE09

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3
Hypersensitivity 9% x x x
Pneumonia 8% x x x
Hypertension 7% x x x
Upper respiratory tract infection 7% x x x
Diabetes mellitus 5% x x
Pleural effusion 4% x x
Alveolitis 3% x x
Gastrointestinal haemorrhage 1% x x
Intestinal perforation 1% x x x
Pericardial effusion 1% x x
Convulsion 1% x
Postoperative wound infection 1% x x
Thrombophlebitis 1% x x x
Impaired healing 1% x x x
Sepsis 1% x x
Rectal haemorrhage 1% x
Infection rare x x x
Extravasation postmarketing x
Pain postmarketing x x x
Reflex sympathetic dystrophy postmarketing x
Rhabdomyolysis postmarketing x x
Stevens-Johnson syndrome postmarketing x x
Swelling postmarketing x
Erythema postmarketing x
Warmth postmarketing x
Complex regional pain syndrome postmarketing x
Infestation NOS rare x
Abdominal distension x
Abdominal pain x x x
Abscess x x
Alveolitis allergic x
Anaphylactic shock x
Anaemia x x x
Angioedema x x x
Anorexia x x
Anxiety x
Arthralgia x x x
Asthenia x x x
Back pain x x x
Bacterial infection x
Mental disorder x
Bronchitis x x
Candida infection x
Cellulitis x x
Chest pain x x x
Conjunctivitis x x x
Connective tissue disorder x x x
Constipation x x x
Cough x x x
Cystitis x x
Dysphagia x
Dehydration x
Depression x x x
Dermatitis x
Dermatitis exfoliative x
Diarrhoea x x x
Dizziness x
Dysgeusia x x x
Dyspnoea x x x
Dysuria x
Ecchymosis x
Eczema x
Oedema x x x
Epistaxis x x x
Rash x x x
Eye disorder x x x
Eye haemorrhage x
Fatigue x
Body temperature increased x x x
Folliculitis x
Gastritis x
Gastrointestinal disorder x x x
Gingival bleeding x
Gingivitis x
Glossitis x
Headache x x x
Cardiac disorder x
Haematuria x
Herpes simplex x x
Herpes zoster x x
Ophthalmic herpes zoster x
Herpes virus infection x
Hypercholesterolaemia x
Hyperglycaemia x x x
Hyperlipidaemia x x x
Hypertriglyceridaemia x x x
Hypocalcaemia x
Hypokalaemia x
Immune system disorder x
Influenza x
Lacrimal disorder x x x
Laryngitis x
Leukopenia x x
Lung disorder x
Lymphopenia x x
Mediastinal disorder x x x
Fungal infection x
Nail disorder x x x
Nausea x x x
Nervous system disorder x x x
Neutropenia x x x
Mouth haemorrhage x
Petechiae x
Pharyngitis x x x
Prurigo x x
Pruritus x x x
Pulmonary embolism x x x
Pulmonary fibrosis x
Renal failure x x x
Rhinitis x x x
Septic shock x
Sinusitis x
Skin infection x
Stomatitis x x
Aphthous stomatitis x x
Thrombocytopenia x x x
Pollakiuria x
Urinary tract infection x x x
Urinary tract disorder x
Angiopathy x
Venous thrombosis x
Viral infection x
Vomiting x x x
Weight decreased x x
Wound infection x x
Chills x x x
Rash pustular x x
Oedema peripheral x x
Hypophosphataemia x x x
Cataract x
Mouth ulceration x
Deep vein thrombosis x x x
Creatinine increased x x
Generalised oedema x
Oedema genital x
Scrotal oedema x
Haemorrhage intracranial x
Phosphatase alkaline increased x x
Vesiculobullous rash x
Aspartate aminotransferase increased x x x
Alanine aminotransferase increased x
Dry skin x x x
Haemoglobin decreased x x
Malnutrition x
Unspecified disorder of skin and subcutaneous tissue x x
Interstitial pneumonia x
Interstitial lung disease x x x
Fatal outcomes x x
Rash macular x
Oral pain x
Myalgia x x x
Decreased appetite x
Blood creatinine increased x
Duodenal perforation x
Glucose tolerance impaired x x x
Mucosal inflammation x x x
Oral herpes x
Anal candidiasis x
Platelet count decreased x x
Rash maculo-papular x x
Pruritus generalised x
Rash generalised x
Face oedema x x
Acne x x x
Bilirubin total increased x x
Febrile neutropenia x
White blood cell count decreased x x
Blood and lymphatic system disorders x
Lymphocyte count decreased x x
Glucose increased x x
Potassium low x x
Insomnia x x x
Phosphorus low x x
Wound complication x
Rash papular x
Eosinophilic pneumonia x
Pneumocystis jirovecii pneumonia x
Exfoliative rash x
Venous thromboembolism x x x
Ageusia x x
Somnolence x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

TEMSIROLIMUS

Side effects:94
Source:FDA Structured Product Label

TEMSIROLIMUS / TORISEL

Side effects:96
Source:FDA

temsirolimus / temsirolimus

Side effects:151
Source:EMA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label