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5-aza-2'-deoxycytidine

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: L01BC08

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6
Thrombocytopenia 24% - 89.2% x x x x x x
Neutropenia 37% - 90.4% x x x x x x
Anaemia 22% - 81.9% x x x x x x
Fatigue 46.5% x x x x x
Nausea 16% - 42.2% x x x x x x
Body temperature increased 28.4% - 53% x x x x x x
Cough 27.3% - 39.8% x x x x x
Constipation 13.6% - 34.9% x x x x x
Dyspnoea 29.3% x x x x x
Diarrhoea 16% - 33.7% x x x x x x
Oedema peripheral 16% - 27.3% x x x x x
Headache 13.6% - 27.7% x x x x x x
Febrile neutropenia 6.17% - 28.9% x x x x x x
Leukopenia 6.06% - 27.7% x x x x x x
Hypoalbuminaemia 17.3% - 24.1% x x x x x
Pneumonia 13.6% - 21.7% x x x x x x
Hyperglycaemia 6.06% - 32.5% x x x x x
Rigors 17.3% - 21.7% x x x x x
Pain in extremity 9.88% - 19.3% x x x x x
Dizziness 12.3% - 21.2% x x x x x
Hyponatraemia 16% - 19.3% x x x x x
Pallor 12.3% - 22.9% x x x x x
Arthralgia 9.88% - 20.5% x x x x x
Back pain 6.17% - 18.2% x x x x x
Vomiting 8.64% - 25.3% x x x x x x
Chills 16.2% x x x x
Petechiae 12.1% - 38.6% x x x x x
Anorexia 9.88% - 23.2% x x x x x
Asthenia 15.2% x x x x x
Ecchymosis 9.09% - 21.7% x x x x x
Decreased appetite 8.08% - 15.7% x x x x x
Abdominal pain 6.17% - 14.5% x x x x x
Insomnia 13.6% - 27.7% x x x x x
Cardiac murmur 11.1% - 15.7% x x x x x
Epistaxis 13.1% x x x x x
Hypokalaemia 12.1% - 21.7% x x x x x
Pharyngitis 7.41% - 15.7% x x x x x x
Rash 8.64% - 19.3% x x x x x
Stomatitis 6.17% - 12% x x x x x x
Dyspepsia 1.23% - 12% x x x x x
Upper respiratory tract infection 10.1% x x x x x x
Anxiety 9.09% - 10.8% x x x x x
Blood alkaline phosphatase increased 8.64% - 10.8% x x x x x
Lymphadenopathy 7.41% - 12% x x x x x
Hyperbilirubinaemia 4.94% - 14.5% x x x x x
Aspartate aminotransferase increased 8.64% - 9.64% x x x x x
Respiratory sounds decreased 8.64% - 9.64% x x x x x
Oral mucosal petechiae 4.94% - 13.3% x x x x x
Cellulitis 7.41% - 12% x x x x x x
Contusion 9.09% x x x x
Depression 9.09% x x x x
Pruritus 2.47% - 10.8% x x x x x
Weight decreased 9.09% x x x x
Mucosal inflammation 9.09% x x x x x
Hyperkalaemia 3.7% - 13.3% x x x x x
Confusional state 3.7% - 12% x x x x x
Tachycardia 8.08% x x x x x
Dry skin 8.08% x x x x
Staphylococcal bacteraemia 8.08% x x x x
Pharyngolaryngeal pain 8.08% x x x x
Lethargy 3.7% - 12% x x x x x
Hypomagnesaemia 5.05% - 24.1% x x x x x
Gingival bleeding 6.17% - 8.43% x x x x x
Blood lactate dehydrogenase increased 6.17% - 8.43% x x x x x
Hypoxia 4.94% - 9.64% x x x x x
Muscle spasms 7.07% x x x x
Urinary tract infection 1.23% - 7.23% x x x x x x
Oedema 5.05% - 18.1% x x x x x
Pain 5.05% - 13.3% x x x x x
Erythema 5.05% - 14.5% x x x x x
Haemorrhoids 3.7% - 8.43% x x x x x
Chest pain 6.06% x x x x x
Ear pain 6.06% x x x x
Hypertension 6.06% x x x x
Toothache 6.06% x x x x
Bone pain 6.06% x x x x
Blood bilirubin increased 6.06% x x x x x
Ascites 2.47% - 9.64% x x x x x
Hypoaesthesia 1.23% - 10.8% x x x x x
Oral candidiasis 2.47% - 6.06% x x x x x x
Dehydration 4.94% - 8.08% x x x x x
Hypotension 4.94% - 11.1% x x x x x
Chest discomfort 3.7% - 7.23% x x x x x
Transfusion reaction 3.7% - 7.23% x x x x x
Loose stools 3.7% - 7.23% x x x x x
Candida infection 1.23% - 9.64% x x x x x
Blood urea increased 1.23% - 9.64% x x x x x
Tenderness 0% - 10.8% x x x x x
Dysphagia 2.47% - 6.02% x x x x x
Cardiac failure congestive 5.05% x x x x x
Musculoskeletal pain 5.05% x x x x
Night sweats 5.05% x x x x
Pancytopenia 5.05% x x x x x
Pleural effusion 5.05% x x x x
Skin lesion 3.7% - 10.8% x x x x x
Muscular weakness 5.05% x x x x
Sinus congestion 5.05% x x x x
Oral pain 5.05% x x x x
Breath sounds abnormal 5.05% x x x x
Tooth abscess 5.05% x x x x
Dysuria 3.7% - 6.02% x x x x x
Intermittent fever 3.7% - 6.02% x x x x x
Tongue ulceration 2.47% - 7.23% x x x x x
Alopecia 1.23% - 8.43% x x x x x
Gastrooesophageal reflux disease 0% - 5.05% x x x x x
Sinusitis 2.47% - 6.06% x x x x x x
Myalgia 1.23% - 9.09% x x x x x
Abdominal pain upper 1.23% - 6.06% x x x x x
Thrombocytosis 1.23% - 5.05% x x x x x
Haematoma 3.7% - 4.82% x x x x x
Lip ulceration 3.7% - 4.82% x x x x x
Protein total decreased 3.7% - 4.82% x x x x x
Chest wall pain 1.23% - 7.23% x x x x x
Catheter related infection 0% - 8.43% x x x x x
Postnasal drip 2.47% - 4.82% x x x x x
Rales 1.23% - 14.5% x x x x x
Urticaria 1.23% - 6.02% x x x x x
Oral soft tissue disorder NOS 1.23% - 6.02% x x x x x
Blood chloride decreased 1.23% - 6.02% x x x x x
Blood bicarbonate increased 1.23% - 6.02% x x x x x
Staphylococcal infection 0% - 7.23% x x x x x
Blood albumin decreased 0% - 7.23% x x x x x
Abdominal distension 1.23% - 4.82% x x x x x
Pollakiuria 1.23% - 4.82% x x x x x
Malaise 1.23% - 4.82% x x x x x
Blood bicarbonate decreased 1.23% - 4.82% x x x x x
Blood bilirubin decreased 1.23% - 4.82% x x x x x
Catheter site erythema 1.23% - 4.82% x x x x x
Abrasion NOS 1.23% - 4.82% x x x x x
Pulmonary oedema 0% - 6.02% x x x x x
Swelling face 0% - 6.02% x x x x x
Vision blurred 0% - 6.02% x x x x x
Musculoskeletal discomfort 0% - 6.02% x x x x x
Bacteraemia 0% - 4.82% x x x x x
Glossodynia 0% - 4.82% x x x x x
Injection site swelling 0% - 4.82% x x x x x
Catheter site pain 0% - 4.82% x x x x x
Haemorrhage 2% x x x x x
Acute febrile neutrophilic dermatosis postmarketing x x x x x
Anaphylactic shock x x x x x x
Atrial fibrillation x x x x x
Mental disorder x x x x x
Bronchitis x
Neoplasm malignant x
Cholecystitis x x x x x
Infection x x x x x x
Connective tissue disorder x x x x x
Drug hypersensitivity x
Eye disorder x x x x x
Gastrointestinal disorder x x x x x x
Cardiac disorder x x x x x
Blood disorder x
Haemoptysis x x x x x
Hypersensitivity x x x x x x
Immune system disorder x
Mediastinal disorder x x x x x x
Mycobacterium avium complex infection x x x x x
Fungal infection x x x x x
Myocardial infarction x x x x x
Nasopharyngitis x
Nervous system disorder x x x x x x
Pulmonary embolism x x x x x
Renal failure x x x x x
Respiratory tract infection x x x x x
Septic shock x
Splenomegaly x x x x x
Supraventricular tachycardia x x x x x
Upper gastrointestinal haemorrhage x x x x x
Urinary tract disorder x x x x x
Angiopathy x x x x x
Pulmonary mass x x x x x
Haemorrhage intracranial x x x x x
Liver function test abnormal x x x x x
Respiratory arrest x x x x x
Malnutrition x x x x x
Unspecified disorder of skin and subcutaneous tissue x x x x x x
Fatal outcomes x
Lung infiltration x x x x x
Gingival pain x x x x x
Urethral haemorrhage x x x x x
Sepsis x x x x x x
Hepatobiliary disease x x x x x
Anaphylactoid reaction x
Oral herpes x
Cardio-respiratory arrest x x x x x
Infestation NOS x x x x x x
Blood and lymphatic system disorders x x x x x
Ear and labyrinth disorders x x x x
Myelosuppression x x x x x
Peridiverticular abscess x x x x x
Mental status changes x x x x x
Lung infection x x x x x
Post procedural pain x x x x x
Cardiomyopathy x x x x x
Post procedural haemorrhage x x x x x
Catheter site haemorrhage x x x x x
Central line infection x x x x x
Bronchopulmonary aspergillosis x x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

decitabine / decitabine

Side effects:41
Source:EMA

DECITABINE / DACOGEN

Side effects:163
Source:FDA

Decitabine

Side effects:188
Source:FDA Structured Product Label

DECITABINE

Side effects:188
Source:FDA Structured Product Label

DECITABINE

Side effects:188
Source:FDA Structured Product Label

DECITABINE

Side effects:188
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label