Search results :

Phenytoin

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: N03AB02

Side effects

Options: Hide MedDRA Preferred Terms ,   display all 25 labels

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Nystagmus Nystagmus 8.2% - 59.1% x x x x x x x x x x x x x x x x x x x x
Somnolence Somnolence 6.7% - 27.3% x x x x x x x x x x x x
Drowsiness x
Tremor Tremor 3.3% - 13.1% x x x x x x x x x x x x x x x x x x x x
Trembling x
Tinnitus Tinnitus 8.9% - 9.1% x
Ataxia Ataxia 8.2% - 18.2% x x x x x x x x x x x x x x x x x x x x
Hypotension Hypotension 0.3% - 9.1% x x x x x x x x x
Ecchymosis Ecchymosis 4.9% - 7.3% x
Stupor Stupor 4.5% - 7.7% x
Depressed level of consciousness Stupor 4.5% - 7.7% x
CNS depression NOS infrequent x x
Amblyopia Amblyopia 2.2% - 9.1% x x
Infection Infection frequent x
Constipation Constipation frequent x x x x x x x x x x x x x x x x x x x x
Dizziness Dizziness 3.3% - 31.1% x x x x x x x x x x x x x x x x x x x x
Syncope infrequent x
Dermatitis Rash frequent x x x x x x x x x x x x x x x x x x x x
Dermatitis x x x x x x x x x x x x x x x x
Rash Rash frequent x x x x x x x x x x x x x x x x x x x x
Body temperature increased Body temperature increased frequent x x x x x x x x x x x x x x x x x x x x
Hypertension Hypertension frequent x
Hypoaesthesia Hypoaesthesia frequent, 2.2% - 9.1% x
Hypokalaemia Hypokalaemia frequent x
Nervousness Nervousness frequent x x x x x x x x x x x x x x x x x x x x
Tension Nervousness frequent x x x x x x x x x x x x x x x x x x x x
Pneumonia Pneumonia frequent x
Speech disorder Speech disorder frequent x
Chills Chills frequent x
Injection site reaction Injection site reaction frequent x
Injury Accidental injury 3.4% - 6.6% x
Intracranial pressure increased Intracranial pressure increased frequent x
Injection site pain Injection site pain frequent x
Hyperreflexia Hyperreflexia frequent x
Thinking abnormal Thinking abnormal frequent x
Mental disability Thinking abnormal frequent x
Face oedema Face oedema frequent x
Muscular weakness Myasthenia frequent x
Headache Headache 2.2% - 8.9% x x x x x x x x x x x x x x x x x x x x
Coordination abnormal Coordination abnormal 4.4% - 7.8% x
Nausea Nausea 0% - 13.6% x x x x x x x x x x x x x x x x x x x
Dry mouth Dry mouth 4.4% - 4.5% x
Hyporeflexia Hyporeflexia 2.8% - 4.9% x
Paraesthesia Paraesthesia 0% - 4.4% x x x x x x x x x x x x
Tingling sensation x
Asthenia Asthenia 0% - 3.9% x x
Fatigue x
Dysgeusia Dysgeusia frequent, 0% - 3.3% x x x x x x
Taste metallic x x x x x x
Taste altered x x x x x x
Pruritus Pruritus 0% - 48.9% x
Vomiting Vomiting 0% - 9.1% x x x x x x x x x x x x x x x x x x x x
Dysarthria Dysarthria frequent, 0% - 2.2% x
Slurred speech x x x x x x x x x x x x x x x x x x x
Osteoarthritis Dysarthria frequent, 0% - 2.2% x
Pelvic pain Pelvic pain 0% - 4.4% x
Tongue disorder Tongue disorder 0% - 4.4% x
Tongue oedema infrequent x
Brain oedema Brain oedema infrequent, 2.2% - 4.5% x
Diplopia Diplopia 0% - 3.3% x
Agitation Agitation 0% - 3.3% x
Hyperkinesia infrequent x
Excitement x
Back pain Back pain 0% - 2.2% x
Tachycardia Tachycardia 0% - 2.2% x
Vertigo Vertigo 0% - 2.2% x x x x x x x
Acidosis Acidosis infrequent x
Albuminuria Albuminuria infrequent x
Alkalosis Alkalosis infrequent x
Amnesia Amnesia infrequent x
Anaemia Anaemia infrequent x
Hypochromic anaemia Hypochromic anaemia infrequent x
Decreased appetite Anorexia infrequent x x
Appetite absent x
Aphasia Aphasia infrequent x
Apnoea Apnoea infrequent x
Arthralgia Arthralgia infrequent x x x x x x x x x
Musculoskeletal discomfort Arthralgia infrequent x x x x x x x x x
Myalgia infrequent x
Asthma Asthma infrequent x
Atelectasis Atelectasis infrequent x
Pneumothorax Atelectasis infrequent x
Pneumothorax infrequent x
Atrial flutter Atrial flutter infrequent x
Bronchitis Bronchitis infrequent x
Bundle branch block Bundle branch block infrequent x
Cachexia Cachexia infrequent x
Vulvovaginal candidiasis Vaginal moniliasis infrequent x
Vulvovaginal mycotic infection Vaginal moniliasis infrequent x
Cerebral infarction Cerebral infarction infrequent x
Coma Coma infrequent x
Confusional state Confusional state infrequent x x x x x x x x x x x x x x x x x x x x
Feeling abnormal Confusional state infrequent x x x x x x x x x x x x x x x x x x x x
Malaise infrequent x
Conjunctivitis Conjunctivitis infrequent x
Cryptococcosis Cryptococcosis infrequent x
Cyanosis Cyanosis infrequent x
Deafness Deafness infrequent, 0% - 2.2% x
Dysphagia Dysphagia infrequent x x
Dehydration Dehydration infrequent x
Delirium Delirium infrequent x
Depersonalisation Depersonalisation infrequent x
Dermatitis contact Dermatitis contact infrequent x
Diabetes insipidus Diabetes insipidus infrequent x
Diarrhoea Diarrhoea infrequent x
Dyspepsia Dyspepsia infrequent x
Dyspnoea Dyspnoea infrequent x
Dysuria Dysuria infrequent x
Ear pain Ear pain infrequent x
Encephalitis Encephalitis infrequent x
Epistaxis Epistaxis infrequent x
Extrapyramidal disorder Extrapyramidal disorder infrequent, 0% - 4.4% x
Flatulence Flatulence infrequent x
Gastritis Gastritis infrequent x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage infrequent x
Cardiac arrest Cardiac arrest infrequent x
Cardiomegaly Cardiomegaly infrequent x
Cardiac failure congestive Cardiac failure congestive infrequent x
Subdural haematoma Subdural haematoma infrequent x
Hemiplegia Hemiplegia infrequent x
Haemoptysis Haemoptysis infrequent x
Hostility Hostility infrequent x
Hyperaesthesia Hyperaesthesia infrequent x
Hyperglycaemia Hyperglycaemia infrequent x
Hyperkalaemia Hyperkalaemia infrequent x
Hyperventilation Hyperventilation infrequent x
Orthostatic hypotension Orthostatic hypotension infrequent x
Influenza Influenza infrequent x
Ketosis Ketosis infrequent x
Muscle spasms Cramps of lower extremities infrequent x
Leukocytosis Leukocytosis infrequent x
Leukopenia Leukopenia infrequent x x x x x x x x x x x x x x x x x x x
Meningitis Meningitis infrequent x
Hypotonia Hypotonia infrequent x
Muscle relaxant therapy Hypotonia infrequent x
Myopathy Myopathy infrequent x
Mydriasis Mydriasis infrequent x
Myoclonus Myoclonus infrequent x
Neurosis Neurosis infrequent x
Oliguria Oliguria infrequent x
Palpitations Palpitations infrequent x
Personality disorder Personality disorder infrequent x
Petechiae Petechiae infrequent x
Pharyngitis Pharyngitis infrequent x
Pneumonia aspiration Pneumonia aspiration infrequent x
Polyuria Polyuria infrequent x
Urine output increased Polyuria infrequent x
Psychotic disorder Psychotic disorder infrequent x
Pulmonary embolism Pulmonary embolism infrequent x
Hyperacusis Hyperacusis infrequent x
Extensor plantar response Extensor plantar response infrequent x
Renal failure Renal failure infrequent x
Rhinitis Rhinitis infrequent x
Scotoma Scotoma infrequent x
Convulsion Convulsion infrequent
Shock Shock infrequent x x x x x x x x x
Syncope infrequent x
Salivary hypersecretion Salivary hypersecretion infrequent x
Sinusitis Sinusitis infrequent x
Skin mass Skin nodule infrequent x
Hyperhidrosis Sweating infrequent x
Syncope Syncope infrequent x
Loss of consciousness Syncope infrequent x
Thrombocytopenia Thrombocytopenia infrequent x x x x x x x x x x x x x x x x x x x x
Thrombophlebitis Thrombophlebitis infrequent x
Urinary incontinence Urinary incontinence infrequent x
Urticaria Urticaria infrequent x
Vaginal inflammation Vaginal inflammation infrequent x
Vaginal infection Vaginal inflammation infrequent x
Urinary retention Urinary retention infrequent x
Encephalopathy Encephalopathy infrequent x
Sinus bradycardia Sinus bradycardia infrequent x
Mood swings Mood swings infrequent x
Affect lability Mood swings infrequent x
Photophobia Photophobia infrequent x
Rash pustular Rash pustular infrequent x
Hypophosphataemia Hypophosphataemia infrequent x x x x x
Hypokinesia Hypokinesia infrequent x
Migraine Migraine infrequent x
Generalised oedema Generalised oedema infrequent x
Fluid retention Generalised oedema infrequent x
Oedema genital Oedema genital infrequent x
Injection site swelling Injection site swelling infrequent x
Tongue oedema Tongue oedema infrequent x
Ventricular extrasystoles Ventricular extrasystoles infrequent x
Injection site haemorrhage Injection site haemorrhage infrequent x
Injection site inflammation Injection site inflammation infrequent x
Liver function test abnormal Liver function test abnormal infrequent x
Eye pain Eye pain infrequent x
Urethral pain Urethral pain infrequent x
Paraesthesia oral Circumoral paresthesia infrequent x
Skin discolouration Skin discolouration infrequent x
Photosensitivity reaction Photosensitivity reaction infrequent x
Malaise Malaise infrequent x
Discomfort Malaise infrequent x
Discomfort x
Ill-defined disorder Malaise infrequent x
Myalgia Myalgia infrequent x
Muscle twitching Muscle twitching infrequent x
Proctalgia Rectal tenesmus infrequent x
Rectal tenesmus Rectal tenesmus infrequent x
Anorectal discomfort Rectal tenesmus infrequent x
Sputum increased Sputum increased infrequent x
Increased bronchial secretion Sputum increased infrequent x
Sepsis Sepsis infrequent x
Akathisia Akathisia infrequent x
Rash maculo-papular Rash maculo-papular infrequent x
Hyperkinesia Hyperkinesia infrequent x
Lymphadenopathy Lymphadenopathy infrequent x x x x x x x x x x x x x x x x x x x x
Paralysis Paralysis infrequent x
Cough Cough increased infrequent x
Insomnia Insomnia infrequent x x x x x x x x x x x x x x x x x x x x
Ileus Ileus infrequent x
Parosmia Parosmia infrequent x
Ageusia Ageusia infrequent x x
Cerebral haemorrhage Cerebral haemorrhage infrequent x
Bradycardia Bradycardia 0.2% x
Anaphylactic shock Anaphylactic shock postmarketing x x x x x x x x x x
Anaphylactoid reaction postmarketing x x x x
Dyskinesia Dyskinesia postmarketing x x x x x x x x x x x x x x x x x x x
Anaphylactoid reaction Anaphylactoid reaction postmarketing x x x x
Agranulocytosis Agranulocytosis x x x x x x x x x x x x x x x x x x x
Anaemia megaloblastic Anaemia megaloblastic x x x x x x x x x x x x x x x x x x x
Breast disorder Breast disorder x
Chorea Chorea x x x x x x x x x x x x x x x x x x x
Connective tissue disorder Connective tissue disorder x
Drug eruption Drug eruption x
Dupuytren's contracture Dupuytren's contracture x
Eosinophilia Eosinophilia x x x x x x x x
Toxic epidermal necrolysis Toxic epidermal necrolysis x x x x x x x x x x x x x x x x
Extravasation Extravasation x x x x x x x x
Fatigue Fatigue x
Fibrosis Fibrosis x
Multiple fractures Fracture x x x x x
Fracture Fracture x x x x x
Gastrointestinal disorder Gastrointestinal disorder x
Gingival hyperplasia Gingival hyperplasia x x x x x x x x x x x x x x x x x x
Gingivitis Gingivitis x
Gynaecomastia Gynaecomastia x
Haemorrhage Haemorrhage x
Haemoglobin Haemorrhage x
Hepatitis toxic Hepatitis toxic x x x x x x x x x x x x x x x x x x x
Hirsutism Hirsutism x x x
Hodgkin's disease Hodgkin's disease x x x x x x x x x x x x x x x x x x
Hodgkin's disease lymphocyte depletion type stage unspecified Hodgkin's disease x x x x x x x x x x x x x x x x x x
Hodgkin's disease lymphocyte predominance type stage unspecified Hodgkin's disease x x x x x x x x x x x x x x x x x x
Hyperplasia Hyperplasia x x x x x x x x x x x x x x x x x
Hypersensitivity Hypersensitivity x x x x x x x x x x
Hypertrichosis Hypertrichosis x x x x x x x x x x x x x x x x x x
Hypocalcaemia Hypocalcaemia x x x x
Immune system disorder Immune system disorder x
Inflammation Inflammation x x x x x x x x
Irritability Irritability x
Systemic lupus erythematosus Systemic lupus erythematosus x x x x x x x x x x x x x x x x x x
Lupus erythematosus x x x x x x x x x x
Lymphoma Lymphoma x x x x x x x x x x x x x x x x x x
Non-Hodgkin's lymphoma Lymphoma x x x x x x x x x x x x x x x x x x
Measles Measles x x x x x x x x x x x x x x
Necrosis Necrosis x x x x x x x x
Tubulointerstitial nephritis Nephritis interstitial x
Nervous system disorder Nervous system disorder x
Osteomalacia Osteomalacia x x x x x
Osteoporosis Osteoporosis x x x x
Pancytopenia Pancytopenia x x x x x x x x x x x x x x x x x x
Peyronie's disease Peyronie's disease x x x x x x x x x x x x x x x x x x
Polyarteritis nodosa Polyarteritis nodosa x x x x x x x x x x x x x x x x
Erythema multiforme Stevens-Johnson syndrome x x x x x x x x x x x x x x x x x
Stevens-Johnson syndrome Stevens-Johnson syndrome x x x x x x x x x x x x x x x x x
Dysphemia Stuttering x
Ventricular fibrillation Ventricular fibrillation x x x x x x x
Weight decreased Weight decreased x
Hepatic function abnormal Hepatic function abnormal x x x x x x x x
Hepatocellular injury Hepatocellular injury x x x x x x x x x x x x x x x x x x x
Liver injury Hepatocellular injury x x x x x x x x x x x x x x x x x x x
Liver injury x x
Purpura Purpuric rash x x x x x x x x x x x x x x x x x
Polyneuropathy Polyneuropathy x x x x x x x x x x x x x x x x x x x
Traumatic liver injury Liver injury x x
Acute hepatic failure Acute hepatic failure x x x x x
Hypopnoea Shallow breathing x
Pseudolymphoma Pseudolymphoma x x x x x x x x x x x x x x x x x x
Abdominal pain upper Epigastric pain x
Asterixis Asterixis x x x x x x x x x x x x x x x x x x x
Tenderness Tenderness x x x x x x x x
Rash morbilliform Rash morbilliform x x x x x x x x x x x x x x x
Hepatotoxicity Hepatotoxicity x
Chest pain Chest discomfort x
Chest discomfort Chest discomfort x
Lung infiltration Lung infiltration x
Hepatobiliary disease Hepatobiliary disease x
Tonic convulsion Tonic convulsion x
Cognitive disorder Cognitive impairment x
Epigastric discomfort Gastric irritation x x
Drug reaction with eosinophilia and systemic symptoms Hypersensitive syndrome x x x x x x x x
Purple glove syndrome Purple glove syndrome x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

PHENYTOIN

Side effects:39
Source:FDA Structured Product Label

Phenytoin

Side effects:46
Source:FDA Structured Product Label

PHENYTOIN / TARO-PHENYTOIN

Side effects:47
Source:Health Canada

PHENYTOIN

Side effects:47
Source:FDA Structured Product Label

Phenytoin

Side effects:48
Source:FDA Structured Product Label

PHENYTOIN

Side effects:48
Source:FDA Structured Product Label

Phenytoin

Side effects:48
Source:FDA Structured Product Label

Phenytoin

Side effects:49
Source:FDA Structured Product Label

PHENYTOIN

Side effects:49
Source:FDA Structured Product Label

PHENYTOIN

Side effects:49
Source:FDA Structured Product Label

PHENYTOIN

Side effects:50
Source:FDA Structured Product Label

PHENYTOIN

Side effects:54
Source:FDA Structured Product Label

PHENYTOIN

Side effects:54
Source:FDA Structured Product Label

PHENYTOIN

Side effects:56
Source:FDA Structured Product Label

Phenytoin

Side effects:56
Source:FDA Structured Product Label

PHENYTOIN

Side effects:181
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label