Cevimeline hydrochloride

Side effects and indications

Whenever possible, frequency information about the side effects was extracted from the labels. Aggregated frequency information for the drug and, if available, placebo is shown. To the right, you can click on shaded boxes to be taken to mentions of the side effect on the label. (In some cases, the side effect cannot be highlighted due to conversion problems.) Information about indications was extracted from the indications and usage sections of the labels.

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Side effect Data for drug Placebo Labels
1 2 3 4 5
Sweating def 18.7% 2.4% x x x x x
Sweating increased 18.7% 2.4% x x x x
Headache def 14.4% 20.1% x x x x x
Nausea def 13.8% 7.9% x x x x x
Sinusitis def 12.3% 10.9% x x x x x
Infection def 6.1% - 11.4% 3% - 9.1% x x x x x
Respiratory tract infection def 11.4% 9.1% x x
Upper respiratory tract infection def 11.4% 9.1% x x
Rhinitis def 11.2% 5.4% x x x x x
Diarrhoea def 10.3% 10.3% x x x x x
Dyspepsia def 7.8% 8.5% x x x x x
Abdominal pain def 7.6% 6.7% x x x x
Pain def 2.8% - 7.6% 1.8% - 6.7% x x x x x
Cough def 6.1% 3% x x x x x
Urinary tract infection def 6.1% 3% x x x x
Pharyngitis def 5.2% 5.4% x x x x x
Vomiting def 4.6% 2.4% x x x x x
Back pain def 4.5% 4.2% x x x x x
Conjunctivitis def 4.3% 3.6% x x x x x
Rash def 4.3% 6% x x x x x
Bronchitis def 4.1% 1.2% x x x x x
Dizziness def 4.1% 7.3% x x x x x
Arthralgia def 3.7% 1.8% x x x x x
Fatigue def 3.3% 1.2% x x x x x
Surgical intervention 3.3% 3% x x x x
Bone pain def 2.8% 1.8% x x x x x
Flushing def 0.3% - 2.4% 0% - 0.6% x x x x x
Hot flush def 2.4% 0% x x x x x
Insomnia def 2.4% 1.2% x x x x x
Salivation def 2.2% 0.6% x x x x x
Salivary hypersecretion def 2.2% 0.6% x x x x
Anxiety def 1.3% 1.2% x x x x x
Rigors 1.3% 1.2% x x x x x
Pollakiuria def 0.9% 1.8% x x x x
Asthenia def 0.5% 0% x x x x x
Aggression def postmarketing x x x x x
Amnesia def postmarketing x x x x x
Aphasia def postmarketing x x x x x
Apnoea def postmarketing x x x x x
Atelectasis def postmarketing x x x x x
Bundle branch block def postmarketing x x x x x
Cholecystitis def postmarketing x x x x
Convulsion def postmarketing x x x x x
Delirium def postmarketing x x x x x
Delusion def postmarketing x x x x x
Failure to thrive def postmarketing x x x x x
Gingival hyperplasia def postmarketing x x x x x
Glycosuria def postmarketing x x x x x
Gout def postmarketing x x x x x
Cardiomegaly def postmarketing x x x x x
Hyperaesthesia def postmarketing x x x x x
Hyperkalaemia def postmarketing x x x x x
Hyperplasia def postmarketing x x x x x
Hypotension def postmarketing x x x x x
Orthostatic hypotension def postmarketing x x x x x
Illusion def postmarketing x x x x x
Intestinal obstruction def postmarketing x x x x x
Lymphocytosis def postmarketing x x x x x
Neurosis def postmarketing x x x x x
Obstruction def postmarketing x x x x x
Oliguria def postmarketing x x x x x
Personality disorder def postmarketing x x x x x
Polyuria def 0.1% 0.6% x x x x x
Yawning def postmarketing x x x x x
Bronchoconstriction def postmarketing x x x x
Urinary retention def postmarketing x x x x x
Apathy def postmarketing x x x x x
Electrolyte abnormality postmarketing x x x x x
Lactic dehydrogenase activity increased postmarketing x x x x x
Paranoid reaction postmarketing x x x x x
Phosphatase alkaline increased postmarketing x x x x x
Abnormal platelets postmarketing x x x x x
Hyperhemoglobinemia postmarketing x x x x x
Erectile dysfunction def postmarketing x x x x x
Hyperproteinaemia def postmarketing x x x x x
Change of bowel habit postmarketing x x x x x
Enlargement abdomen def postmarketing x x x x x
Dementia def postmarketing x x x x x
Paralysis def postmarketing x x x x x
Blood pressure fluctuation postmarketing x x x x x
Sexual dysfunction postmarketing x x x x x
Gait disturbance def postmarketing x x x x x
Aggressive reaction postmarketing x x x x x
Abscess def x x x x x
Agranulocytosis def x x x x x
Albuminuria def x x x x x
Alopecia def x x x x x
Amenorrhoea def x x x x x
Anaemia def x x x x x
Hypochromic anaemia def x x x x x
Angina pectoris def x x x x x
Anorexia def x x x
Appendicitis def x x x x x
Arrhythmia def x x x x x
Arthritis def x x x x x
Rheumatoid arthritis def x x x x x
Asthma def x x x x x
Bacterial infection def x x x x
Blepharitis def x x x x x
Bone disorder def x x x x x
Bronchospasm def x x x x x
Bursitis def x x x x x
Candidiasis def x x x x x
Carcinoma def x x x x x
Basal cell carcinoma def x x x x
Squamous cell carcinoma def x x x x x
Cardiovascular disorder def x x x x x
Carpal tunnel syndrome def x x x x
Cellulitis def x x x x
Chest pain def x x x x x
Choking def x x x x x
Cholelithiasis def x x x x x
Colitis def x x x x x
Colitis ulcerative def x x x x x
Coma def x x x x x
Confusional state def x x x x x
Constipation def x x x
Corneal opacity def x x x x x
Ulcerative keratitis def x x x x x
Cystitis def x x x x x
Cyst def x x x x x
Deafness def x x x x x
Dysphagia def x x x x x
Dehydration def x x x x x
Dental caries def x x x x x
Depersonalisation def x x x x x
Dermatitis def x x x x x
Dermatitis contact def x x x x x
Scleroderma def x x x x x
Diabetes mellitus def x x x x x
Diplopia def x x x x x
Diverticulitis def x x x x x
Duodenitis def x x x x x
Dysgeusia def x x x x x
Dyskinesia def x x x x x
Dysmenorrhoea def x x x x x
Dyspnoea def x x x x x
Dysuria def x x x x x
Ear pain def x x x
Eczema def x x x x x
Oedema def x x x x x
Effusion def x x x x x
Embolism def x x x x x
Endocrine disorder def x x x x x
Enterocolitis def x x x x x
Eosinophilia def x x x x x
Epididymitis def x x x x x
Epistaxis def x x x x x
Eructation def x x x x x
Oesophageal disorder def x x x x x
Oesophageal stenosis def x x x x x
Oesophagitis def x x x x x
Congenital eye disorder def x x x x
Eye haemorrhage def x x x x x
Eye infection def x x x
Fasciitis def x x x x x
Body temperature increased def x x x
Fibrosis def x x x x x
Flatulence def x x x x x
Furunculosis def x x x x x
Gastritis def x x x x x
Gastroenteritis def x x x x x
Gastrooesophageal reflux disease def x x x x
Gastrointestinal haemorrhage def x x x x x
Gingivitis def x x x x x
Glaucoma def x x x x x
Glossitis def x x x x x
Tongue geographic def x x x x x
Goitre def x x x x x
Hallucination def x x x x x
Cardiac disorder def x x x x x
Cardiac murmur def x x x x x
Blood disorder def x x x x x
Haematoma def x x x x x
Haematuria def x x x x x
Haemoptysis def x x x x x
Haemorrhage def x x x x x
Haemorrhoids def x x x x x
Hepatitis def x x x x x
Herpes NOS def x x x x x
Herpes simplex def x x x x x
Herpes zoster def x x x x x
Hiccups def x x x x
Hypercalcaemia def x x x x x
Hypercholesterolaemia def x x x x x
Hyperglycaemia def x x x x x
Hyperlipidaemia def x x x x x
Hypersensitivity def x x x x x
Hypertension def x x x x x
Hypertriglyceridaemia def x x x x x
Hypertrophy def x x x x x
Salivary gland enlargement x x x x
Hypoaesthesia def x x x x x
Hyphaema def x x x x x
Hypoglycaemia def x x x x x
Hypokalaemia def x x x x x
Hyponatraemia def x x x x x
Hypothyroidism def x x x x x
Incontinence def x x x x x
Infarction def x x x x x
Influenza def x x x
Irritable bowel syndrome def x x x x x
Irritability def x x x x x
Ischaemia def x x x x x
Arthropathy def x x x x x
Keratitis def x x x x x
Keratoconjunctivitis def x x x x x
Calculus of kidney def x x x x x
Laryngitis def x x x x x
Cramps of lower extremities x x x x x
Leg pain x x x x x
Leukocytosis def x x x x x
Leukopenia def x x x x x
Leukorrhea def x x x x x
Lichen unspecified def x x x x x
Lichen planus def x x x x x
Chronic obstructive pulmonary disease def x x x x x
Breast pain def x x x x x
Melaena def x x x x x
Menorrhagia def x x x x x
Menstrual disorder def x x x x x
Metrorrhagia def x x x x x
Motion sickness def x x x x x
Multiple sclerosis def x x x x x
Cramp muscle def x x x x x
Hypertonia def x x x
Musculoskeletal disorder def x x x x
Fungal infection def x x x x
Mydriasis def x x x x x
Myocardial infarction def x x x x x
Myopia def x x x x x
Nail disorder def x x x x x
Necrosis def x x x x x
Neoplasm def x x x x x
Nephrosis def x x x x x
Nervous system disorder def x x x x x
Neuralgia def x x x x x
Nightmare def x x x x x
Nocturia def x x x x x
Mouth haemorrhage def x x x x x
Osteomyelitis def x x x x x
Osteoporosis def x x x x x
Otitis def x x x x
Otitis media def x x x x
Ovarian cyst def x x x x x
Ovarian disorder def x x x x x
Pallor def x x x x x
Palpitations def x x x x x
Paraesthesia def x x x x x
Paronychia def x x x x x
Peptic ulcer def x x x x x
Pericarditis def x x x x x
Phlebitis def x x x x x
Pleural disorder def x x x x x
Pleural effusion def x x x x x
Pleurisy def x x x x x
Pneumonia def x x x x
Postoperative hemorrhage def x
Prostatic disorder def x x x x x
Pruritus def x x x x x
Pruritus genital x x x x x
Pulmonary embolism def x x x x x
Pulmonary fibrosis def x x x x
Purpura def x x x x x
Pyelonephritis def x x x x x
Pyuria def x x x x x
Rectal disorder def x x x x x
Respiratory disorder def x x x x x
Retinal disorder def x x x x x
Rosacea def x x x x x
Scleritis def x x x x x
Seborrhoeic dermatitis def x x x x x
Sialoadenitis def x x x x
Skin disorder def x x x x
Skin ulcer def x x x x
Speech disorder def x x x x x
Gastric ulcer def x x x x x
Stomatitis def x x x x x
Ulcerative stomatitis x x x x x
Cerebrovascular accident def x x x x x
Syncope def x x x x x
Synovitis def x x x x x
Tachycardia def x x x x x
Supraventricular tachycardia def x x x x
Tendonitis def x x x x x
Tenosynovitis def x x x x x
Thirst def x x x x x
Thrombocytopenia def x x x x x
Thrombophlebitis def x x x x x
Costochondritis def x x x x x
Onychomycosis def x x x x x
Tinnitus def x x x x x
Tongue disorder x x x x x
Tooth disorder def x x x x x
Toothache def x x x x x
Tremor def x x x
Ulcer def x x x x x
Urethral disorder def x x x x x
Urinary incontinence def x x x x x
Micturition disorder def x x x x x
Urticaria def x x x x x
Uterine haemorrhage def x x x x x
Vaginal inflammation def x x x x x
Angiopathy def x x x x x
Vasculitis def x x x x x
Vertigo def x x x
Hepatitis viral def x x x x x
Viral infection def x x x x x
Visual impairment def x x x
Vitreous detachment def x x x x x
Common wart def x x x x x
Weight increased def x x x x x
Weight decreased def x x x x x
Xerophthalmia def x x x x x
Operative haemorrhage def x x x
Urogenital disorder x x x x x
Agitation def x x x x x
Mood swings x x x x x
Photopsia x x x x x
Oedema peripheral def x x x
Cataract def x x x x x
Hepatic function abnormal x x x x x
Plantar fasciitis def x x x x x
Migraine def x x x x x
Periorbital oedema def x x x x x
Amylase increased x x x x x
Blood urea increased x x x x x
Tongue discolouration x x x x x
Endometrial disorder def x x x x x
Skin hypertrophy x x x x x
Kidney function abnormal x x x x x
Manic psychosis x x x x
Muscular weakness def x x x x x
Retrosternal pain x x x x x
Eye pain def x x x
Hyporeflexia x x x x
Aspartate aminotransferase increased def x x x x x
Alanine aminotransferase increased def x x x x x
Skin discolouration def x x x x x
Dry skin def x x x x x
Deep thrombophlebitis x x x x x
Photosensitivity reaction def x x x x x
Eruption lichenoid def x x x x x
Necrosis ischaemic def x x x x x
Nail discolouration def x x x x x
Vaginitis atrophic def x x x x x
Sickness x x x x x
Malaise def x x x x x
Myalgia def x x x
Precordial pain x x x x x
Increased appetite x x x x x
Rectal tenesmus def x x x x x
Strangury x x x x x
Thinking abnormal x x x x x
Discomfort def x x x x x
Ache def x
Rash erythematous x x x x
Muscle contractions involuntary x x x x x
Salivary gland pain x x x
Tongue ulceration x x x x x
Peripheral ischaemia def x x x x x
Lymphadenopathy cervical def x x x x x
Urine abnormality x x x x x
Hypertension worsened x x x x x
Bullous eruption x x x x x
Skin cold clammy x x x x x
Depression aggravated x x x x x
Arthritis aggravated x x x x x
Allergy aggravated x x x x x
Crying abnormal x x x x x
Retinal deposits x x x x x
Hepatic enzyme increased x x x x x
Oedema mouth x x x x x
Skin exfoliation x x x x x
Pulmonary congestion x x x x x
Sepsis def x x x x x
Nasal ulcer x x x x x
Rectal haemorrhage def x x x x x
Eruption x x x x x
Mucosal inflammation def x x x x x
Mania def x x x x x
Extrasystoles def x x x x x
Genital candidiasis x x x x x
Photosensitivity def x x x x x
Sticky skin x x x x x
Dysaesthesia def x x x x x
Lupus erythematosus def x x x x x
Avascular necrosis femoral head x x x x x
Hyperkinesia def x x x x x
Neuropathy def x x x x x
Lymphadenopathy def x x x x x
Electrocardiogram T wave inversion def x x x x x
Coordination abnormal x x x x x
Electrocardiogram abnormal x x x x x
Detachment psychological x x x x x
Face oedema def x x x x x
Bladder discomfort x x x x x
Urine flow decreased x x x x
Breast pain female x x x x x
Renal pain x x x x x
Obstructive airways disorder def x x x x x
Breast disorder female x x x x x
Onychia x x x x x
Acne def x x x x x
Hyperuricaemia def x x x x x
Phlebitis superficial x x x x x
Thrombocytosis def x x x x x
Thrombocytopenic purpura def x x x x x
Hyperkeratosis def x x x x x
Ileus def x x x x x
Hearing impaired def x x x x x
Breast neoplasm def x x x x x
Parosmia def x x x x x
Dysphonia def x x x x x
Weakness def x x x x x
Somnolence def x x x x x
Vaginal haemorrhage def x x x x x
Indication Labels
Dry mouth def x x x x x

Information

More information: STITCH, PubChem and possibly Wikipedia or Medpedia

ATC Code: N07AX03

Legend

Color scheme: standard – alternative

100%    
75%    
50%    
10%    
frequent (1% to 100%)    
infrequent (0.1% to 1%)    
rare (<0.1%)    
postmarketing    
0%    
no frequency information    
not found on label    

Labels

Labels were obtained from different sources and potentially contain different sets of side effects. If you click on the label name, a HTML version of the label will be shown with proteins, chemicals and side efffects highlighted using Reflect.

  1. CEVIMELINE HYDROCHLORIDE / EVOXAC : 383 side effects (Drugs@FDA)
  2. CEVIMELINE HYDROCHLORIDE / EVOXAC : 398 side effects (Drugs@FDA)
  3. CEVIMELINE HYDROCHLORIDE / EVOXAC : 405 side effects (Drugs@FDA)
  4. cevimeline : 412 side effects (FDA XML label)
  5. CEVIMELINE : 413 side effects (FDA XML label)