Search results :

Diclofenac

More information: STITCH, PubChem and possibly Wikipedia

ATC Codes: D11AX18, M01AB05, M02AA15, S01BC03

Side effects

Options: Hide MedDRA Preferred Terms ,   display all 49 labels

MedDRA Preferred Term Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Dry skin Dry skin postmarketing, 0% - 41.9% 0.301% - 6.86% x x x
Gastrointestinal disorder Gastrointestinal disorder 6% - 9% 6% x x x x x x x x
Gastrointestinal symptom NOS x
Induration Induration 2% - 9% x x
Upper respiratory tract infection Upper respiratory tract infection 8%
Skin exfoliation Skin exfoliation 4% - 24% x x
Application site reaction Application site reaction 1.13% - 84% 0.904% - 2.17% x x x x
Nasopharyngitis Nasopharyngitis 6%
Decreased appetite Anorexia common x x x x x x x x
Decreased appetite postmarketing, common x x x
Appetite absent x
Flatulence Flatulence common, 2% - 3.84% 0% - 2% x x x x x x x x x x x x x x x
Headache Headache postmarketing — 0% - 32.7% 2% - 26.9% x x x x x x x x x x x x x x x x x
Vertigo Vertigo common x x x x x x x x x x x x x
Vomiting Vomiting common, 3% - 9% 1% - 12% x x x x x x x x x x x x x x x
Injection site reaction Injection site reaction common
Injection site pain Injection site pain common
Rash Eruption common x x x
Rash postmarketing — 0% - 46% 1.51% - 2.86% x x x x x x x x x x x x x x x x
Transaminases increased Transaminases increased common x x x x x
Injection site induration Injection site induration common
Dermatitis Rash postmarketing — 0% - 46% 1.51% - 2.86% x x x x x x x x x x x x x x x x
Dermatitis 1% - 2% x x x x
Malnutrition Malnutrition 2% - 8% x
Influenza Influenza 0% - 10% 4.57% x
Infection Infection 2.71% - 11.5% 2.41% - 4.57% x x x x x x
Cough Cough 4%
Cough increased x
Pharyngitis Pharyngitis postmarketing, 2% - 8% 3.92% - 6.86% x x x
Pruritus Pruritus very rare — 1% - 59% 0.602% - 8% x x x x x x x x x x x x x x x x x
Osteoarthritis Osteoarthritis 2.6% - 5% x
Arthropathy 0% - 7.69% 12% - 15.4% x
Application site rash Application site rash 3.5% 0.685% x
Urinary tract infection Urinary tract infection 0.775% - 7% x
Bronchitis Bronchitis 3% x
Diarrhoea Diarrhoea postmarketing — 0% - 6% 2.11% - 3% x x x x x x x x x x x x x x x x x
Nausea Nausea postmarketing — 0% - 27% 0.904% - 37% x x x x x x x x x x x x x x x x x
Pain in extremity Pain in extremity 3% 1%
Abdominal pain upper Abdominal pain upper 3% 1% x
Stomach ache x
Epigastric pain x
Procedural pain Procedural pain 3%
Nervous system disorder Nervous system disorder 2% - 3% x x x x x x x
Ecchymosis Ecchymosis 2.09% 0.301% x x x x x x
Abdominal pain Abdominal pain postmarketing — 0% - 5.93% 3.01% - 5.14% x x x x x x x x x x x x x x x
Abdominal cramps x x
Stomach ache x
Gastrointestinal pain Abdominal pain postmarketing — 0% - 5.93% 3.01% - 5.14% x x x x x x x x x x x x x x x
Arthralgia Arthralgia 0% - 40.4% 37.1% x
Musculoskeletal discomfort Arthralgia 0% - 40.4% 37.1% x
Myalgia postmarketing, 0% - 3% x x x
Back pain Back pain postmarketing, 0% - 15.4% 7.43% x x x
Dermatitis contact Dermatitis contact postmarketing, 0% - 33% 0% - 1.81% x x x
Dyspepsia Dyspepsia postmarketing — 0% - 9.62% 1% - 4% x x x x x x x x x x x x x x x x
Heartburn x x x
Pain Pain postmarketing, 0% - 30% 10.9% x x x
Stinging
Rhinitis Rhinitis 2% x
Abdominal discomfort Abdominal discomfort 2% x
Blood creatinine increased Blood creatinine increased 2% 0%
Creatinine increased postmarketing, 0% - 2% x x x
Skin cancer Skin carcinoma 0% - 6%
Contusion Contusion 0.775% - 3% x
Conjunctivitis Conjunctivitis 0% - 4% x x x
Sinus congestion Sinus congestion 0.775% - 1.54% x
Application site induration Application site induration 0.775% - 1.54% x
Injury Accidental injury postmarketing, 0% - 4% 2.11% x x x
Dizziness Dizziness postmarketing — 0% - 10% 0.5% - 16% x x x x x x x x x x x x x x x x x
Syncope x x x
Lightheadedness x
Paraesthesia Paraesthesia very rare — 0% - 20% 0.904% - 10.3% x x x x x x x x x x x x x x x x
Tingling sensation x
Myalgia Myalgia postmarketing, 0% - 3% x x x
Somnolence Somnolence rare, 1% 1% - 1.83% x x x x x x x x x x
Drowsiness postmarketing, rare x x x x x x x x x x
Application site pruritus Application site pruritus 0.767% 0.114% x
Arthritis Rheumatoid arthritis 0.7% x
Arthritis x
Rheumatoid arthritis Rheumatoid arthritis 0.7% x
Application site erythema Application site erythema 0.657% 0.342% x
Breath odour Breath odour postmarketing, 1.21% 0.301% x x x
Sinusitis Sinusitis 0% - 5% 0.602% - 1% x x x
Application site paraesthesia Application site paraesthesia 0.548% 0.342% x
Dysgeusia Dysgeusia very rare — 0% - 3.81% 4.57% x x x x x x
Bad taste
Hypercholesterolaemia Hypercholesterolaemia 0% - 2% x
Hyperaesthesia Hyperaesthesia 0% - 3%
Hyperglycaemia Hyperglycaemia 0% - 2% x x x
Skin ulcer Skin ulcer 0% - 2%
Migraine Migraine 0% - 2%
Blood creatine phosphokinase increased Creatine phosphokinase increased 0% - 4%
Rash pustular Vesiculobullous rash 0% - 4% x
Rash pustular x
Dermatitis bullous Vesiculobullous rash 0% - 4% x
Dermatitis bullous very rare x x
Bullous eruption very rare x x x x x x x x
Scab Scab 1% x
Acne Acne 0% - 4%
Application site dryness Application site dryness 0.438% 0.342% x x
Application site vesicles Application site vesicles 0.329% 0% x
Application site irritation Application site irritation common, 0.219% 0% x
Flushing Flushing 0.2% x
Application site papules Application site papules 0.11% 0% x
Asthma Asthma postmarketing — 0% - 2% x x x x x x x x x x x x x x x x
Exacerbation of asthma
Cardiovascular disorder Cardiovascular disorder postmarketing x x x
Dyspnoea Dyspnoea postmarketing — 0% - 2% x x x x x x x x x x x x x
Ear pain Ear pain postmarketing x x x
Oedema Oedema postmarketing — 0% - 33% 0% - 32% x x x x x x x x x x x x x x x x x
Eye disorder Eye disorder postmarketing x x x x x x x x x
Gastritis Gastritis rare x x x x x x x x x x x
Gastroenteritis Gastroenteritis postmarketing x x x
Gastrointestinal haemorrhage Gastrointestinal haemorrhage rare x x x x x x x x x x x x
Haematemesis Haematemesis rare x x x x x x x x x x x
Haemorrhage Haemorrhage rare x x x x x x x x x x x x x x
Haemoglobin Haemorrhage rare x x x x x x x x x x x x x x
Hepatitis Hepatitis rare x x x x x x x x x x x x x
Hypersensitivity Hypersensitivity postmarketing — 0% - 3% x x x x x x x x x x x x
Hypotension Hypotension rare x x x x x x x x x x x x x
Jaundice Jaundice rare x x x x x x x x x x x x x
Laryngospasm Laryngospasm postmarketing x x x
Laryngitis Laryngitis postmarketing x x x
Muscle spasms Cramps of lower extremities postmarketing x x x
Cramp muscle x
Lethargy Lethargy postmarketing x x
Liver disorder Liver disorder rare x x x x x x
Hepatocellular injury Liver disorder rare x x x x x x
Foetor hepaticus Liver disorder rare x x x x x x
Melaena Melaena rare x x x x x x x x x x x x x
Proctitis Proctitis rare
Shock Shock rare x x x x x x
Syncope x x x
Mouth ulceration Ulcerative stomatitis postmarketing x x x
Mouth ulceration postmarketing x x x
Swelling Swelling postmarketing x x
Urticaria Urticaria postmarketing — 0.2% x x x x x x x x x x x x x x x x
Dry mouth Dry mouth postmarketing x x x x x x x x
Skin odour abnormal Body odor postmarketing x x x
Cataract Cataract postmarketing x x
Stomatitis Mouth ulceration postmarketing x x x
Stomatitis very rare x x x x x x x x x x x
Musculoskeletal stiffness Neck stiffness postmarketing x x x
Nuchal rigidity Neck stiffness postmarketing x x x
Diarrhoea haemorrhagic Diarrhoea haemorrhagic rare x x x x x x x x
Injection site necrosis Injection site necrosis rare
Drug ineffective Lack of drug effect postmarketing x x
Eye pain Eye pain postmarketing, 0% - 2% x x x
Skin discolouration Skin discolouration postmarketing x x x
Intestinal ulcer Intestinal ulcer rare x
Swollen tongue Swollen tongue postmarketing x
Gastrointestinal ulcer Gastrointestinal ulcer rare x x x x x x
Lip swelling Lip swelling postmarketing x x
Skin burning sensation Skin burning sensation postmarketing x
Rectal haemorrhage Rectal haemorrhage postmarketing x x x x x x
Anaphylactic shock Anaphylactoid reaction rare x x x x x x x x x
Anaphylactic shock x x x x x
Anaphylactoid reaction Anaphylactoid reaction rare x x x x x x x x x
Blood pressure increased Blood pressure increased postmarketing x
Visual impairment Abnormal vision postmarketing x x x
Visual disturbance very rare x x x x x
Visual impairment very rare x x x x
Agranulocytosis Agranulocytosis very rare x x x x x x x x x x x x x
Alopecia Alopecia very rare, 0% - 2% x x x x x x x x x x x x x
Anaemia Anaemia very rare x x x x x x x x x x x
Secondary anemia x
Aplastic anaemia Aplastic anaemia very rare x x x x x x x x x x x x x
Haemolytic anaemia Haemolytic anaemia very rare x x x x x x x x
Angioedema Angioedema very rare x x x x x x x x x x
Anxiety Anxiety very rare, 0% - 2% x x x x x x x x x x x x x
Chest pain Chest pain very rare — 0% - 2% x x x x x x x x x x x
Colitis Colitis very rare x x x x x x x x x x x
Colitis ulcerative Colitis ulcerative very rare x x x x x x x x x
Proctocolitis Colitis ulcerative very rare x x x x x x x x x
Constipation Constipation very rare, 0% - 8% 0.301% - 4% x x x x x x x x x x x x x x x x x
Crohn's disease Crohn's disease very rare x x x x x x x x x
Dermatitis exfoliative Dermatitis exfoliative very rare x x x x x x x x x x x x
Diplopia Diplopia very rare x x x x x x x x x
Eczema Eczema very rare, postmarketing x x x x x x x x x x x x
Toxic epidermal necrolysis Toxic epidermal necrolysis very rare x x x x x x x x x x x x x
Erythema multiforme Erythema multiforme very rare x x x x x x x x x x x x x x
Stevens-Johnson syndrome very rare x x x x x x x x x x x x x
Oesophageal disorder Oesophageal disorder very rare x x x x x x
Glossitis Glossitis very rare x x x x x x x x x x x
Cardiac failure Cardiac failure very rare x x x x x x x x
Haematuria Haematuria very rare, 0% - 2% x x x x x x x x x x x x x
Haemorrhoids Haemorrhoids very rare x
Hemorrhoids aggravated very rare
Hypertension Hypertension very rare — 0% - 3% 1% x x x x x x x x x x x x x x
Irritability Irritability very rare x x x x x x x x x x
Renal failure acute Renal failure acute very rare x x x x x x x x x x
Renal papillary necrosis Renal papillary necrosis very rare x x x x x x x x x x
Leukopenia Leukopenia very rare x x x x x x x x x x
Meningitis aseptic Meningitis aseptic very rare x x x x x x x x x
Myocardial infarction Myocardial infarction very rare x x x x x x x x x x x
Acute coronary syndrome Myocardial infarction very rare x x x x x x x x x x x
Tubulointerstitial nephritis Nephritis interstitial very rare x x x x x x x x x x x
Tubulointerstitial nephritis very rare x x
Nephrotic syndrome Nephrotic syndrome very rare x x x x x x x x x x
Nightmare Nightmare very rare x x x x x x x x x
Palpitations Palpitations very rare, postmarketing x x x x x x x x x x x x x x x x
Pancreatitis Pancreatitis very rare x x x x x x x x x x x x
Pneumonia Pneumonia very rare, 0% - 2% x x x x x x x x x x x x
Proteinuria Proteinuria very rare x x x x x x x x x x x x x
Protein urine present Proteinuria very rare x x x x x x x x x x x x x
Psychotic disorder Psychotic disorder very rare x x x x x x x x x x
Purpura Purpura very rare x x x x x x x x x x x
Purpuric rash
Vascular purpura Purpura very rare x x x x x x x x x x x
Henoch-Schonlein purpura Henoch-Schonlein purpura very rare x x x x x x x x x
Convulsion Convulsion very rare x x x x x x x x x x x x x
Stevens-Johnson syndrome Stevens-Johnson syndrome very rare x x x x x x x x x x x x x
Cerebrovascular accident Cerebrovascular accident very rare x x x x x x
Thrombocytopenia Thrombocytopenia very rare x x x x x x x x x x x x x
Tinnitus Tinnitus very rare x x x x x x x x x x x x x
Tremor Tremor very rare x x x x x x x x x x x x x
Erythema Erythema very rare — 4% x x x x x x x x x x x x
Redness
Vasculitis Vasculitis very rare x x x x x x x x x x x x
Encephalopathy Encephalopathy very rare x x x
Hepatic failure Hepatic failure very rare x x x x x x x
Injection site abscess Injection site abscess very rare
Enterocolitis haemorrhagic Hemorrhagic colitis very rare x x x x x x x x x
Hepatic necrosis Hepatic necrosis very rare x x x x x x
Photosensitivity reaction Photosensitivity reaction very rare, 0% - 3% x x x x x x x x
Photosensitivity x x x x x
Disorientation Disorientation very rare x x x x x x x x x x
Memory impairment Memory impairment very rare x x x x x x x x
Erectile dysfunction Erectile dysfunction very rare x x x
Hepatitis fulminant Hepatitis fulminant very rare, rare x x x x x x x x x x
Vision blurred Vision blurred very rare, postmarketing x x x x x x x x x x x x x x x
Face oedema Face oedema very rare, postmarketing x x x x x x x
Toxic shock syndrome Toxic shock syndrome very rare x
Insomnia Insomnia very rare x x x x x x x x x x x x x x
Deafness Hearing impaired very rare x x x x x x x x x x
Hearing impaired Hearing impaired very rare x x x x x x x x x x
Partial hearing loss x x
Intestinal diaphragm disease Intestinal diaphragm disease very rare x x
Abdominal distension Abdominal distension x
Amblyopia Amblyopia x x
Angina pectoris Angina pectoris x x
Aphasia Aphasia x
Arrhythmia Arrhythmia x x x x x x
Arteriosclerosis Arteriosclerosis x
Asthenia Asthenia postmarketing, 0% - 2% x x x x x x
Fatigue x x x
Mental disorder Mental disorder x x x x x x
Bronchospasm Bronchospasm x x
Neoplasm malignant Carcinoma x
Neck pain Neck pain 0% - 2% x
Tongue coated Tongue coated x x
Coma Coma x x x
Confusional state Confusional state x x x x
Feeling abnormal Confusional state x x x x
Malaise x x x x x x x
Conjunctivitis allergic Conjunctivitis allergic
Corneal disorder Corneal disorder
Corneal oedema Corneal oedema
Corneal opacity Corneal opacity
Ulcerative keratitis Ulcerative keratitis x
Cystitis Cystitis x x x
Bladder pain Cystitis x x x
Cystitis noninfective Cystitis x x x
Dental caries Dental caries x
Depression Depression x
Dysmenorrhoea Dysmenorrhoea x
Dysthymic disorder Dysthymic disorder x
Dysuria Dysuria x x x
Eosinophilia Eosinophilia x x x x
Epistaxis Epistaxis x x
Eructation Eructation x x x
Oesophagitis Oesophagitis x x x
Fatigue Fatigue x x x
Body temperature increased Body temperature increased x x x x
Vitreous floaters Vitreous floaters x
Furuncle Furunculosis x
Gingivitis Gingivitis x
Gout Gout x
Hair disorder Hair disorder x
Hallucination Hallucination x x x
Cardiac disorder Cardiac disorder x x x x x x
Cardiac failure congestive Cardiac failure congestive x x x x x
Hepatorenal syndrome Hepatorenal syndrome x
Hernia Hernia x
Herpes simplex Herpes simplex 0% - 2%
Hyperventilation Hyperventilation x
Hypoaesthesia Hypoaesthesia x
Hypoglycaemia Hypoglycaemia x
Immune system disorder Immune system disorder x x x x x x
Intestinal perforation Intestinal perforation x
Iritis Iritis
Eye pruritus Eye pruritus
Arthropathy Arthropathy 0% - 7.69% 12% - 15.4% x
Keratitis Keratitis
Lacrimal disorder Lacrimal disorder x
Lacrimal structural disorder Lacrimal disorder x
Laryngeal oedema Laryngeal oedema x
Mediastinal disorder Mediastinal disorder x x x x x x
Meningitis Meningitis x x x
Hypertonia Hypertonia x
Nail disorder Nail disorder x
Nervousness Nervousness x x x x
Tension Nervousness x x x x
Neuritis Neuritis x
Neuropathy peripheral Neuritis x
Night blindness Night blindness x
Nocturia Nocturia x
Oliguria Oliguria x x x x
Pancytopenia Pancytopenia x x x
Peptic ulcer Peptic ulcer x x x x x x
Tooth abscess Abscess periodontal x
Phlebitis Phlebitis 0% - 2%
Polyuria Polyuria x x x
Urine output increased Polyuria x x x
Anorectal disorder Rectal disorder x
Renal failure Renal failure x x x
Scotoma Scotoma x
Seborrhoeic dermatitis Seborrhoeic dermatitis
Skin mass Skin nodule 0% - 2% x
Speech disorder Speech disorder x
Aphthous stomatitis Aphthous stomatitis x x
Hyperhidrosis Sweating x
Sweating increased 0.612% x x x
Syncope Syncope x x x
Loss of consciousness Syncope x x x
Tachycardia Tachycardia x x x x
Testicular disorder Testicular disorder x
Thirst Thirst x
Toothache Toothache x
Ulcer Ulcer x x x x x x
Pollakiuria Pollakiuria x
Urethral disorder Urinary tract disorder x x x x x x
Urinary tract disorder Urinary tract disorder x x x x x x
Angiopathy Angiopathy x x x x x x
Vasodilation procedure Vasodilation x x x
Viral infection Viral infection
Weight increased Weight increased x
Weight decreased Weight decreased x
Wheezing Wheezing x
Chills Chills 0% - 2% x
Burning sensation Burning sensation
Oedema peripheral Oedema peripheral x
Hypokinesia Hypokinesia 0% - 2%
Hepatic function abnormal Hepatic function abnormal x
Bleeding time prolonged Bleeding time prolonged x x x
Ventricular extrasystoles Ventricular extrasystoles x
Hyperchlorhydria Hyperchlorhydria x x
Gastric pH decreased Hyperchlorhydria x x
Skin hypertrophy Skin hypertrophy
Renal impairment Kidney function abnormal x x x
Bone pain Bone pain x
Aspartate aminotransferase increased Aspartate aminotransferase increased 0% - 3%
Alanine aminotransferase increased Alanine aminotransferase increased 0% - 4% 0%
Skin irritation Skin irritation
Endophthalmitis Ocular hyperaemia
Ocular hyperaemia Ocular hyperaemia
Corneal deposits Corneal deposits
Eyelid oedema Eyelid oedema
Swelling of eyelid
Skin disorder Unspecified disorder of skin and subcutaneous tissue x x x x x x
Prostatic specific antigen increased Prostatic specific antigen increased x
Malaise Malaise x x x x x x x
Discomfort Malaise x x x x x x x
Ill-defined disorder Malaise x x x x x x x
Thinking abnormal Thinking abnormal x
Mental disability Thinking abnormal x
Cerebration impaired x x
Respiratory depression Respiratory depression x x x
Pulmonary function test decreased Respiratory depression x x x
Disturbance in attention Cerebration impaired x x
Eye irritation Eye irritation
Hepatic enzyme increased Hepatic enzyme increased x x x
Erythema of eyelid Erythema of eyelid
Azotaemia Azotaemia x
Sepsis Sepsis x x x
Punctate keratitis Punctate keratitis x
Hepatobiliary disease Hepatobiliary disease x x x x x x
Fluid retention Fluid retention x
Water retention x
Epidermolysis Epidermolysis x
Atrophy Atrophy x
Corneal perforation Corneal perforation x
Corneal erosion Corneal erosion x
Platelet count decreased Platelet count decreased x
Lacrimation increased Lacrimation
Rash maculo-papular Rash maculo-papular 0% - 2% x
Agitation Hyperkinesia x
Hyperkinesia Hyperkinesia x
Bradycardia Bradycardia x
Lymphadenopathy Lymphadenopathy x x x
Coordination abnormal Coordination abnormal x
Gait disturbance Gait disturbance x
Blood creatinine abnormal Creatinine abnormal NOS x x
Eyelids pruritus Eyelids pruritus
Infestation Infestation NOS
Sleep disorder Sleep disorder x
Eye allergy Eye allergy
Corneal infiltrates Corneal infiltrates x
Dermatitis atopic Allergic skin reaction x x
Muscular weakness Myasthenia x
Corneal thinning Corneal thinning x
Excoriation Abrasion NOS x
Conjunctival hyperaemia Conjunctival hyperaemia
Vaginal haemorrhage Vaginal haemorrhage x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

DICLOFENAC

Side effects:6
Source:FDA Structured Product Label

DICLOFENAC

Side effects:9
Source:FDA Structured Product Label

Diclofenac

Side effects:13
Source:FDA Structured Product Label

Diclofenac

Side effects:16
Source:FDA Structured Product Label

DICLOFENAC

Side effects:61
Source:FDA Structured Product Label

DICLOFENAC

Side effects:72
Source:FDA Structured Product Label

DICLOFENAC POTASSIUM / SANDOZ-DICLOFENAC RAPIDE

Side effects:91
Source:Health Canada

Diclofenac

Side effects:98
Source:FDA Structured Product Label

diclofenac

Side effects:100
Source:FDA Structured Product Label

DICLOFENAC

Side effects:101
Source:FDA Structured Product Label

Diclofenac sodium / DICLOFENAC TABLETS

Side effects:104
Source:medicines.org.au

Diclofenac

Side effects:105
Source:FDA Structured Product Label

VOLTAREN RAPID 25 / Voltaren Rapid 25, Tablet

Side effects:105
Source:Medsafe

diclofenac potassium / VOLTFAST

Side effects:106
Source:medicines.org.au

VOLTAREN D / Voltaren D, Dispersible tablet

Side effects:106
Source:Medsafe

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label