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Sunitinib

More information: STITCH, PubChem (stereo-specific compound: 1) and possibly Wikipedia

ATC Code: L01XE04

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5
Blister 18% x x x x
Lipase increased 16% x x x x x
Dizziness 15% x x x x x
Neuropathy peripheral 10% x x x
Hyperuricaemia 10% x x
Hypertension 8% x
Hypophosphataemia 5% - 10% x x x
Periorbital oedema 7% x x x x
Lacrimation increased 6% x x x x
Asthenia 5% x x x x x
Diarrhoea 5% x x x x x
Hyponatraemia 5% x x x
Amylase increased 5% x x x x x
Nausea 4% x x x x x
Abdominal pain 2% - 3% x x x x
Anorexia 3% x x x x x
Anaemia 2% x x x x
Dyspnoea 2% x x x x
Glucose decreased 2% x x x
Back pain 1% - 2% x x x x
Glucose increased 1% - 2% x x x
Hypothyroidism postmarketing, 2% - 4-7% x x x x x
Rash 1% x x x x x
Fatigue 1% - 10% x x x x x
Hypokalaemia 1% x x x
Thrombocytopenia postmarketing, 1% x x x x
Vomiting 1% - 2% x x x x x
Bone pain 1% x x
Mucosal inflammation 1% - 2% x x x x x
Potassium increased 1% x x x
Adrenal insufficiency 1% x x
Convulsion 1% x
Bradycardia 1% x
Abscess postmarketing x x x
Angioedema postmarketing x x x x
Bronchitis postmarketing x x x
Neoplasm malignant postmarketing x x
Candida infection postmarketing x x
Cellulitis postmarketing x x x
Cerebral infarction postmarketing x x x x
Transient ischaemic attack postmarketing x x x x
Cholecystitis postmarketing x x x x
Infection postmarketing x x x x x
Connective tissue disorder postmarketing x x x x
Endocrine disorder postmarketing x x x
Erythema multiforme postmarketing x x x
Oesophagitis postmarketing x x x x
Fistula postmarketing x x x x
Gastrointestinal disorder postmarketing x x x x
Cardiac disorder postmarketing x x x
Cardiac failure postmarketing x x x
Haemorrhage postmarketing, 2% x x x x x
Hypersensitivity postmarketing x x x x
Hyperthyroidism postmarketing x x x
Immune system disorder postmarketing x x x x
Renal failure acute postmarketing x x x x
Myopathy postmarketing x x x x
Nasopharyngitis postmarketing x x x x
Neoplasm postmarketing x x x
Nephrotic syndrome postmarketing x x x
Nervous system disorder postmarketing x x x
Neutropenia postmarketing, 2% x x x x
Osteomyelitis postmarketing x x x
Pneumonia postmarketing x x x
Proteinuria postmarketing x x
Pulmonary embolism postmarketing x x x
Respiratory tract infection postmarketing x x x
Rhabdomyolysis postmarketing x x x x
Septic shock postmarketing x x x
Skin infection postmarketing x x x x
Cerebrovascular accident postmarketing x x x x x
Thyroiditis postmarketing x x x x
Tumour lysis syndrome postmarketing x x x
Urinary tract infection postmarketing x x x
Urinary tract disorder postmarketing x x x x
Angiopathy postmarketing x x x x
Pyoderma gangrenosum postmarketing x x x x
Malnutrition postmarketing x x x
Unspecified disorder of skin and subcutaneous tissue postmarketing x x x x
Fatal outcomes postmarketing x x x
Necrotising fasciitis postmarketing x x x
Sepsis postmarketing x x x x
Hepatobiliary disease postmarketing x x x x
Acalculous cholecystitis postmarketing x x x
Tumour necrosis postmarketing x x x x
Oral herpes postmarketing x x x
Dysfunction thyroid postmarketing x x x
Infestation NOS postmarketing x x x x
Blood and lymphatic system disorders postmarketing x x x x
Thromboembolic event postmarketing x x x
Cardiomyopathy postmarketing x x x
Renal impairment postmarketing x x x x
Ageusia postmarketing x x x
Thrombotic microangiopathy postmarketing x x x x
Myocardial disorder postmarketing x x x
Abdominal distension x
Alopecia x x x x x
Arrhythmia x
Arthralgia x x x x
Bacterial infection x
Mental disorder x
Burkitt's lymphoma x
Oral candidiasis x
Cheilitis x
Chest pain x x
Constipation x x x x x
Cough x x x x
Sudden death x
Dysphagia x
Dehydration x x x
Depression x x x x
Dermatitis x
Disseminated intravascular coagulation x
Diverticulitis x
Dysgeusia x x x x
Dyspepsia x x x x x
Eczema x
Oedema x x x x
Toxic epidermal necrolysis x
Epistaxis x x x x x
Eructation x
Reflux esophagitis x
Eye disorder x
Body temperature increased x x x x x
Flank pain x x
Flatulence x x x x
Flushing x
Gastrooesophageal reflux disease x x
Gingival bleeding x
Gingivitis x x
Glossodynia x x x x x
Glossitis x x
Headache x x x x
Cardiac failure congestive x x
Haematemesis x x
Haematochezia x x
Blood disorder x
Haematoma x x
Peritoneal haemorrhage x
Haemoptysis x x x x
Haemorrhoids x x
Hepatitis x
Hypercalcaemia x
Hyperaesthesia x
Hyperglycaemia x x x
Hyperkalaemia x x x
Hypernatraemia x x x
Hypoaesthesia x
Hypocalcaemia x
Hypoglycaemia x
Infarction x
Intestinal perforation x
Left ventricular failure x
Leukopenia x x x
Liver abscess x
Lymphopenia x x x
Mediastinal disorder x
Melaena x x
Metrorrhagia x x
Multi-organ failure x
Musculoskeletal pain x
Fungal infection x
Nail disorder x
Nasal congestion x
Metastasis x
Pain x x x x
Pain in extremity x x x x x
Pancreatitis x x x
Pancytopenia x
Paraesthesia x
Pericardial effusion x
Pleural effusion x
Pneumothorax x
Prurigo x
Pruritus x x
Proctalgia x
Renal failure x
Shock x
Congenital skin disorder x x
Skin disorder x
Skin lesion x
Muscle spasms x
Stevens-Johnson syndrome x
Stomatitis x x x x x
Aphthous stomatitis x x
Thrombosis x
Thyrotoxicosis x
Torsade de pointes x
Erythema x x x
Upper respiratory tract infection x
Viral infection x
Weight decreased x x x x
Dry mouth x x x x
Chills x x x x
Hepatic failure x x
Oedema peripheral x x x
Hepatic function abnormal x
Lower respiratory tract infection x
Mouth ulceration x x x
Rectal abscess x
Deep vein thrombosis x x
Gingival abscess x
Creatinine increased x
Gastrointestinal perforation x
Hair discoloration x
Impaired healing x
Pulmonary haemorrhage x x
Myocardial ischaemia x
Muscular weakness x
Phosphatase alkaline increased x x
Electrocardiogram QT prolonged x
Aspartate aminotransferase increased x x x
Alanine aminotransferase increased x x
Skin discolouration x x x x x
Dry skin x x x x x
Hypogeusia x x
Blindness cortical x
Haemoglobin decreased x x
Eyelid oedema x
Apoptosis x
Skin hyperpigmentation x
Leukoderma x
Anal fistula x
Rash macular x
Oral pain x x x x
Myalgia x x x x
Dyspnoea exertional x
Nasal dryness x
Decreased appetite x x x
Abdominal discomfort x
Abdominal pain upper x x
Rash erythematous x
Rash follicular x
Tongue ulceration x x
Hepatotoxicity x
Blood uric acid increased x
Blood creatinine increased x
Skin exfoliation x
Pancreatic abscess x
Oesophageal candidiasis x
Gingival pain x x
Hypoalbuminaemia x
Mg reduced x x x
Subcutaneous abscess x
Wound haemorrhage x
Left ventricular dysfunction x x
Abdominal abscess x
Dermatitis psoriasiform x
Perineal abscess x
Perirectal abscess x
Rectal haemorrhage x
Anal abscess x
Blood bilirubin increased x
Splinter haemorrhages x
Platelet count decreased x x
Oral discomfort x x x
Rash maculo-papular x
Hair colour changes x x x x
Blood pressure increased x
Rash generalised x
Tooth abscess x
Influenza like illness x x
Urine color abnormal x
Chromaturia x
Face oedema x
Laryngeal pain x
Pigmentation disorder x
Ca++ increased x
Yellow skin x x
Abscess limb x
Thyrotropin high x
Sodium high x
Hot flush x
Primary hypothyroidism x x x
Acne x
Taste altered x x x
Bilirubin total increased x
Ejection fraction decreased x x
Febrile neutropenia x
White blood cell count decreased x
Blood thyroid stimulating hormone increased x
Lymphocyte count decreased x
Mucosal dryness x x
Limb discomfort x
Myelosuppression x x
Albumin low x
Potassium low x x x
Sodium decreased x x x
Calcium low x x x
Hyperkeratosis x
Raised liver function tests x x
Alertness decreased x
Insomnia x x x x
Phosphorus low x
Acute coronary syndrome x
Abdominal sepsis x
Respiratory failure x
Rash papular x
Exfoliative rash x
Oropharyngeal pain x x
Osteonecrosis of jaw x
Destructive thyroiditis x
Posterior reversible encephalopathy syndrome x x
Unspecified visual loss x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

sunitinib

Side effects:74
Source:BC Cancer

SUNITINIB

Side effects:119
Source:FDA Structured Product Label

sunitinib / sunitinib

Side effects:217
Source:EMA

Color scheme:

standardalternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label