Famciclovir
Side effects
Options: Show MedDRA Preferred Terms
| Side effect | Data for drug | Placebo | Labels | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | |||
| Upper respiratory tract infection | 31.8% | 31.7% | x | x | |||||||||
| Infection | 24.7% | 25.4% | x | x | |||||||||
| Sinusitis | 19.5% | 15.9% | x | x | |||||||||
| Pharyngitis | 11% | 14.3% | x | x | |||||||||
| Headache | postmarketing — 5.3% - 39.3% | 3.9% - 42.9% | x | x | x | x | x | x | x | x | x | x | x |
| Back pain | 0.602% - 12.3% | 14.3% | x | x | |||||||||
| Nausea | postmarketing — 1.5% - 12.5% | 3.2% - 11.6% | x | x | x | x | x | x | x | x | x | x | x |
| Neutropenia | 3.2% | 1.5% | x | x | x | ||||||||
| Enzyme abnormality | 2.2% | 3.2% | x | x | x | ||||||||
| Dyspepsia | 1.3% - 5.2% | 1.2% - 11.1% | x | x | x | x | x | ||||||
| Diarrhoea | 1.3% - 9% | 0% - 9.5% | x | x | x | x | x | x | x | x | x | ||
| Dysmenorrhoea | 0% - 7.6% | 0% - 6.3% | x | x | x | x | |||||||
| Vomiting | very rare — 0.602% - 4.8% | 0% - 3.4% | x | x | x | x | x | x | x | x | x | x | x |
| Fatigue | 0.6% - 4.8% | 0% - 3.4% | x | x | x | x | x | x | x | x | x | ||
| Insomnia | 1.2% - 1.84% | x | |||||||||||
| Abdominal pain upper | 0.613% - 2.41% | x | |||||||||||
| Abdominal pain | 0% - 7.9% | 0% - 7.9% | x | x | x | x | x | x | x | x | x | ||
| Dizziness | very rare — 0% - 2.41% | 0% - 3.1% | x | x | x | x | x | x | x | x | x | x | x |
| Nasopharyngitis | 0% - 2.64% | 0.787% | x | x | x | ||||||||
| Creatine phosphokinase increased | 0.7% - 2% | x | x | ||||||||||
| Hyperbilirubinaemia | 1.3% | 1.6% | x | x | x | ||||||||
| Leukopenia | 1.3% | 0% - 0.9% | x | x | x | x | x | x | |||||
| Pharyngolaryngeal pain | 0.602% - 1.84% | x | |||||||||||
| Pruritus | very rare — 0% - 3.7% | 0% - 2.7% | x | x | x | x | x | x | x | x | x | x | x |
| Somnolence | very rare — 0.6% - 1.2% | 1.1% - 2.7% | x | x | x | x | x | x | x | x | x | x | x |
| Body temperature increased | 1.1% | 0% | x | x | x | ||||||||
| Flatulence | 0.2% - 4.8% | 0% - 1.6% | x | x | x | x | x | x | |||||
| Constipation | 1% | 0% | x | x | x | ||||||||
| Sweating increased | 1% | 0% | x | x | x | ||||||||
| Upset stomach | 0.602% - 1.23% | x | |||||||||||
| Anxiety | 0% - 1.23% | x | |||||||||||
| Palpitations | 0% - 1.23% | x | x | ||||||||||
| Fungal infection | 0% - 1.2% | x | |||||||||||
| Migraine | 0.2% - 3.1% | 0% - 0.7% | x | x | x | ||||||||
| Gamma-glutamyltransferase increased | 0.6% | 1.4% | x | x | x | ||||||||
| Rigors | 0.6% | 1.4% | x | x | x | ||||||||
| Angioedema | postmarketing, uncommon | x | x | x | x | ||||||||
| Anorexia | 0.5% | 1.4% | x | x | x | ||||||||
| Herpes zoster | 0.5% | 1.4% | x | x | x | ||||||||
| Dry mouth | 0% - 1.23% | 1.2% | x | x | x | x | |||||||
| Periorbital oedema | postmarketing, uncommon | x | x | x | x | ||||||||
| Eyelid oedema | postmarketing, uncommon | x | x | x | x | ||||||||
| Pharyngeal oedema | postmarketing, uncommon | x | x | x | x | ||||||||
| Face oedema | postmarketing, uncommon | x | x | x | x | ||||||||
| Hepatic enzyme increased | 0.2% | 1.4% | x | x | x | ||||||||
| Anaemia | 0.1% | 0% | x | x | x | ||||||||
| Mental disorder | postmarketing | x | x | x | x | x | x | x | x | ||||
| Confusional state | postmarketing — uncommon | x | x | x | x | x | x | x | x | x | x | x | |
| Delirium | postmarketing | x | x | x | x | x | x | ||||||
| Toxic epidermal necrolysis | postmarketing | x | x | x | x | x | x | x | x | x | x | x | |
| Erythema multiforme | postmarketing | x | x | x | x | x | x | x | x | x | x | x | |
| Gastrointestinal disorder | postmarketing | x | x | x | x | x | |||||||
| Hallucination | very rare — rare | x | x | x | x | x | x | x | x | x | x | x | |
| Jaundice cholestatic | very rare — rare | x | x | x | x | x | x | x | x | ||||
| Musculoskeletal disorder | postmarketing | x | x | x | |||||||||
| Nervous system disorder | postmarketing | x | x | x | x | x | x | x | x | ||||
| Stevens-Johnson syndrome | postmarketing | x | x | x | x | x | x | x | x | x | x | x | |
| Thrombocytopenia | very rare — rare | x | x | x | x | x | x | x | x | x | x | x | |
| Urticaria | very rare — uncommon | x | x | x | x | x | x | x | x | x | x | x | |
| Liver function test abnormal | very rare — common | x | x | x | x | x | x | x | x | x | |||
| Unspecified disorder of skin and subcutaneous tissue | postmarketing | x | x | x | x | x | x | x | x | ||||
| Disorientation | postmarketing | x | x | x | x | x | x | ||||||
| Hepatobiliary disease | postmarketing | x | x | x | x | x | x | x | x | ||||
| Blood and lymphatic system disorders | postmarketing | x | x | x | x | x | x | x | x | ||||
| Arthralgia | very rare, postmarketing | x | x | x | |||||||||
| Rash | very rare — 0% - 3.3% | 0% - 1.6% | x | x | x | x | x | x | x | x | x | ||
| Myalgia | very rare, postmarketing | x | x | x | |||||||||
| Cardiac disorder | x | ||||||||||||
| Jaundice | x | x | x | ||||||||||
| Renal failure acute | x | x | x | ||||||||||
| Paraesthesia | 0% - 2.6% | 0% | x | x | x | ||||||||
| Tinnitus | 0% | 1.4% | x | x | x | ||||||||
| Lipase increased | x | x | x | ||||||||||
| Leukocytoclastic vasculitis | x | ||||||||||||
Indications
Information about indications was extracted from the indications and usage sections of the labels.
| Indication | Labels | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Genital herpes | x | x | x | x | x | x | x | x | x | ||||
| Herpes labialis | x | x | x | x | x | x | x | x | |||||
| Herpes simplex | x | x | x | ||||||||||
| Herpes zoster | x | x | x | x | x | x | x | ||||||
| Immunocompromised | x | x | x | x | x | ||||||||
| Infection | x | x | x | ||||||||||
| Mucocutaneous herpes simplex | x | x | |||||||||||
| Ophthalmic herpes zoster | x | x | x | ||||||||||
| Pain | x | x | |||||||||||
| Post herpetic neuralgia | x | x | x | ||||||||||
| Pruritus | x | x | |||||||||||
| Rash | x | x | x | x | x | ||||||||
| Scab | x | x | x | ||||||||||
| Tenderness | x | x | |||||||||||
Color scheme:
standard – alternative
| 100% | ||
| 75% | ||
| 50% | ||
| 10% | ||
| frequent (1% to 100%) | ||
| infrequent (0.1% to 1%) | ||
| rare (<0.1%) | ||
| postmarketing | ||
| 0% | ||
| no frequency information | ||
| not found on label |
