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Ifosfamide

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: L01AA06

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5
Alopecia 1-83% - 83% x x x x x
Nausea 58% x x x x x
Vomiting 58% - 56-81% x x x x x
Haematuria 46% - 6-92% x x x x x
Frank hematuria 12% x x
CNS toxicity 12% x x x
Thrombocytopenia 10% x x x x x
Nephrotoxicity 6% x x
Renal impairment 6% x x x
Cystitis haemorrhagic 1-10% x x
Hepatic function abnormal 3% x x
Phlebitis 2% x x x
Body temperature increased postmarketing, 1% - 8% x x x x x
Fever of unknown origin 1% x x x
Thrombophlebitis 1% x x
Anorexia 1% x x x x
Coagulopathy 1% x x
Dermatitis 1% x x x x x
Diarrhoea 1% x x x x
Encephalitis 1% x x
Fatigue 1% x x x
Hypersensitivity postmarketing, 1% x x x x x
Neuropathy peripheral 1% x x
Renal failure 1% x
Salivation 1% x x
Stomatitis 1% x x x x
Polyneuropathy postmarketing, 1% x x x x x
Malaise 1% x x x
Convulsions generalised 1% x x
Constipation postmarketing, 1% x x x x
Hypertension postmarketing, 1% x x x x
Hypotension postmarketing, 1% x x x x
Cardiotoxicity postmarketing, 1% x x x x
Abdominal pain postmarketing x
Agranulocytosis postmarketing x
Alveolitis allergic postmarketing x
Amenorrhoea postmarketing x x
Amnesia postmarketing x
Anaphylactic shock postmarketing x
Haemolytic anaemia postmarketing x
Anaemia neonatal postmarketing x
Angina pectoris postmarketing x
Angioedema postmarketing x
Arrhythmia postmarketing x x
Arthralgia postmarketing x
Atrial fibrillation postmarketing x
Atrial flutter postmarketing x
Azoospermia postmarketing x x
Mental disorder postmarketing x
Breast disorder postmarketing x
Bronchospasm postmarketing x
Neoplasm malignant postmarketing x
Renal cell carcinoma postmarketing x
Congestive cardiomyopathy postmarketing x
Catatonia postmarketing x
Chest pain postmarketing x
Cholestasis postmarketing x
Colitis postmarketing x
Infection postmarketing, 8% x x x x x
Conjunctivitis postmarketing x
Connective tissue disorder postmarketing x
Cough postmarketing x
Cyst postmarketing x
Deafness postmarketing x
Delirium postmarketing x
Delusion postmarketing x
Disseminated intravascular coagulation postmarketing x
Dysarthria postmarketing x
Dyspnoea postmarketing x
Echolalia postmarketing x
Oedema postmarketing x
Endocrine disorder postmarketing x
Enterocolitis postmarketing x
Enuresis postmarketing x
Toxic epidermal necrolysis postmarketing x
Rash postmarketing x
Extrapyramidal disorder postmarketing x
Eye disorder postmarketing x
Fanconi syndrome postmarketing x x x x x
Faecal incontinence postmarketing x
Microsomia postmarketing x
Flushing postmarketing x
Gastrointestinal disorder postmarketing x
Gastrointestinal haemorrhage postmarketing x
Cardiac arrest postmarketing x
Cardiac disorder postmarketing x
Cardiac failure postmarketing x x x
Haemolytic uraemic syndrome postmarketing x
Venoocclusive liver disease postmarketing x
Herpes zoster postmarketing x
Hyperglycaemia postmarketing x
Hyperhidrosis postmarketing x
Pulmonary hypertension postmarketing x
Hypocalcaemia postmarketing x
Hypokalaemia postmarketing x
Immune system disorder postmarketing x
Inappropriate antidiuretic hormone secretion postmarketing x x
Infertility postmarketing x
Inflammation postmarketing x x
Renal failure chronic postmarketing x x x
Bundle branch block left postmarketing x
Left ventricular failure postmarketing x
Acute lymphocytic leukaemia postmarketing x
Acute myeloid leukaemia postmarketing x
Acute promyelocytic leukaemia postmarketing x
Progressive multifocal leukoencephalopathy postmarketing x
Lymphoma postmarketing x
Non-Hodgkin's lymphoma postmarketing x
Mediastinal disorder postmarketing x
Premature menopause postmarketing x
Methaemoglobinaemia postmarketing x
Movement disorder postmarketing x
Multi-organ failure postmarketing x
Mutism postmarketing x x
Fungal infection postmarketing x
Myelodysplastic syndrome postmarketing x
Myocardial infarction postmarketing x
Myocarditis postmarketing x
Nail disorder postmarketing x
Neoplasm postmarketing x
Nervous system disorder postmarketing x
Neuralgia postmarketing x
Oligospermia postmarketing x
Osteomalacia postmarketing x
Ovarian disorder postmarketing x
Pain postmarketing x
Pain in extremity postmarketing x
Palpitations postmarketing x
Pancreatitis postmarketing, 1% x x x
Pancytopenia postmarketing x
Paraesthesia postmarketing x
Pericardial effusion postmarketing x
Pericarditis postmarketing x
Petechiae postmarketing x
Pleural effusion postmarketing x
Pneumonia postmarketing x
Polyp postmarketing x
Polyuria postmarketing x
Supraventricular extrasystoles postmarketing x
Pruritus postmarketing x
Pulmonary oedema postmarketing, 1% x x x
Pulmonary embolism postmarketing x
Pulmonary fibrosis postmarketing x
Acute respiratory distress syndrome postmarketing x
Rhabdomyolysis postmarketing x
Rickets postmarketing x
Convulsion postmarketing x x x x x
Cardiogenic shock postmarketing x
Septic shock postmarketing x
Salivary hypersecretion postmarketing x
Status epilepticus postmarketing x
Stevens-Johnson syndrome postmarketing x
Swelling postmarketing x
Tinnitus postmarketing x
Tubulointerstitial nephritis postmarketing x
Tumour lysis syndrome postmarketing x
Erythema postmarketing x
Urinary tract disorder postmarketing x
Urticaria postmarketing x
Angiopathy postmarketing x
Vasculitis postmarketing x
Ventricular fibrillation postmarketing x
Ventricular tachycardia postmarketing x
Vertigo postmarketing x
Hepatitis viral postmarketing x
Chills postmarketing x
Polydipsia postmarketing x
Hepatic failure postmarketing x
Bundle branch block right postmarketing x
Acute leukaemia postmarketing x
Hypophosphataemia postmarketing x
Panic attack postmarketing x
Deep vein thrombosis postmarketing x
Swelling face postmarketing x
Ventricular extrasystoles postmarketing x
Growth retardation postmarketing x
Skin necrosis postmarketing x
Portal vein thrombosis postmarketing x
Nephrogenic diabetes insipidus postmarketing x x
Malnutrition postmarketing x
Skin hyperpigmentation postmarketing x x
Unspecified disorder of skin and subcutaneous tissue postmarketing x
Interstitial pneumonia postmarketing, 1% x x x
Interstitial lung disease postmarketing x
Fatal outcomes postmarketing x
Metabolic acidosis postmarketing, 31% x x x x x
Rash macular postmarketing x
Myalgia postmarketing x
Muscle twitching postmarketing x
Asterixis postmarketing x
Perseveration postmarketing x
Tenderness postmarketing x
Eye irritation postmarketing x
Mucosal ulceration postmarketing x
Aminoaciduria postmarketing x
Hypoxia postmarketing x
Sepsis postmarketing x
Caecitis postmarketing x
Hepatobiliary disease postmarketing x
Leukoencephalopathy postmarketing x
Hepatitis fulminant postmarketing x
Mucosal inflammation postmarketing x
Mania postmarketing x
Myocardial depression postmarketing x
Capillary leak syndrome postmarketing x
Vision blurred postmarketing x x x
Dysaesthesia postmarketing x
Bradycardia postmarketing x
Electrocardiogram QRS complex abnormal postmarketing x
Electrocardiogram T wave inversion postmarketing x
Bradyphrenia postmarketing x
Gait disturbance postmarketing x
Ejection fraction decreased postmarketing x
Ovarian failure postmarketing x
Infestation NOS postmarketing x
Blood and lymphatic system disorders postmarketing x
Ear and labyrinth disorders postmarketing x
Blood oestrogen decreased postmarketing x
Blood gonadotrophin increased postmarketing x
Myelosuppression postmarketing x x x
Electrocardiogram ST segment abnormal postmarketing x
Feeling of residual urine postmarketing x
Myocardial haemorrhage postmarketing x
Cardiomyopathy postmarketing x
Cytolytic hepatitis postmarketing x
Haematotoxicity postmarketing x
Urine phosphate increased postmarketing x x x
Febrile bone marrow aplasia postmarketing x
Respiratory failure postmarketing x
Ileus postmarketing x
Sarcoma postmarketing x
Hearing impaired postmarketing x
Ovulation disorder postmarketing x
Paranoia postmarketing x
Radiation recall reaction (dermatologic) postmarketing x
Infusion site reactions postmarketing x
Posterior reversible encephalopathy syndrome postmarketing x
Logorrhoea postmarketing x
Visual impairment postmarketing x
Acidosis x x x
Renal tubular acidosis x x x x
Anaemia x x x x
Asthenia x x
Coma x x x x
Confusional state x x x x
Dizziness x x x x
Dysuria x x x x
Extravasation x
Hallucination x x x x
Haematemesis x x
Haemorrhage x x
Incontinence x
Nephropathy x
Renal failure acute x x
Renal neoplasm x
Leukopenia x x x x
Necrosis x
Obstruction x
Pelvic neoplasm x
Proteinuria x x x x
Pollakiuria x x x x
Urinary incontinence x
Ventricular arrhythmia x x
Stupor x
Agitation x
Brain cancer metastatic x
Disorientation x x x x
Hallucination, auditory x
Neurotoxicity x
Hepatotoxicity x
Microscopic hematuria x x x
Lung fibrosis interstitial x
Arrhythmia supraventricular x
Electrocardiogram ST segment x x
Nephropathy toxic x x
Drug interaction x
Serum creatinine increased x x
Psychosis depressive x x x x
Febrile neutropenia x x
Cerebral arteriosclerosis x
Pulmonary toxicity x
Rash papular x
Renal rickets x x x x
Renal tubular necrosis x x
Somnolence x x x x
Bladder irritation x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

IFOSFAMIDE

Side effects:51
Source:FDA Structured Product Label

IFOSFAMIDE

Side effects:51
Source:FDA Structured Product Label

IFOSFAMIDE / IFOSFAMIDE FOR INJECTION, USP

Side effects:63
Source:Health Canada

ifosfamide

Side effects:65
Source:BC Cancer

IFOSFAMIDE

Side effects:232
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label