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Metformin

More information: STITCH, PubChem and possibly Wikipedia

ATC Code: A10BA02

Side effects

Options: Show MedDRA Preferred Terms,   display all 38 labels

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19 20
Diarrhoea very common, 9.6% - 53.2% 2.6% - 11.7% x x x x x x x x x x x x x x x x x x
Gastrointestinal disorder common, 42% - 48.3% x x
Nausea very common, 6.5% - 25.5% 1.5% - 8.3% x x x x x x x x x x x x x x x x x
Vomiting very common, 3.45% - 25.5% 1.5% - 8.3% x x x x x x x x x x x x x x x x
Infection 20.5% - 20.9% x x x x x
Anorexia very common x x x x x x
Gastrointestinal symptom NOS very common x x x x x x
Abdominal bloating very common x x x x x
Hypoglycaemia 13.7% 4.9% x x x x x x x x x x x x
Flatulence very common, 12.1% 5.5% x x x x x x x x x x x x x x x x
Asthenia 9.2% 5.5% x x x x x x x x
Accidental injury 5.58% - 7.31% x x x x
Dyspepsia 4.2% - 12.5% 4.1% x x x x x x x x x x x
Abdominal discomfort 6.4% 4.8% x x x x x x
Headache 4.7% - 5.7% 4.8% x x x x x x x x x x x
Constipation 2.87% - 5.02% x x x x x
Abdominal pain 4.02% - 7.39% x x x x x x x x x x
Rhinitis 4.2% - 5.6% x x x x
Dysgeusia common, 3% x x x x x x
Taste metallic 3% x x x x x x x
Abdominal distension 0.575% - 7.89% x
Dermatitis very rare, common x x x x x
Rash very rare, common x x x x x x x x x x x x x x x
Hepatitis very rare x
Acidosis x x
Anaemia megaloblastic x x x x x x
Angina unstable x
Breast disorder
Chest pain x
Connective tissue disorder x
Contusion x
Dehydration x x x x x
Distention x x x x x
Dizziness x x x x x x x
Drowsiness x
Dyspnoea x x x x x x x x x
Ear pain x
Eye disorder
Fatigue
Flushing x x x x x x x x x
Seasonal allergy x
Cardiac disorder x
Heartburn x x x x x
Blood disorder
Hypertension x
Hypoaesthesia x
Hypotension x
Body temperature decreased x
Immune system disorder x
Influenza x x x x x x x x x
Lethargy
Mediastinal disorder x
Cramp muscle x
Fungal infection x
Nail disorder x x x x x x x x x
Nasal congestion x
Nervous system disorder x
Neutropenia
Pain in extremity x
Palpitations x x x x x x x x x
Pancreatitis x
Paraesthesia
Pruritus x
Sinus headache x
Syncope
Taste disorders x x x x x x x x x
Thrombocytopenia
Tonsillitis x
Toothache x
Tremor x
Erythema x x x
Upper respiratory tract infection x x x x x
Urticaria x
Angiopathy x
Muscle strain x
Chills x x x x x x x x x
Oedema peripheral
Migraine
Liver function test abnormal
Sinus congestion
Viral diarrhoea x
Ketonuria x
Abnormal faeces x x x x x x x x x
Malnutrition
Unspecified disorder of skin and subcutaneous tissue x
Lightheadedness x x x x x x x x x
Ketoacidosis x x
Malaise x x
Myalgia x x x x x x x x x x x
Abdominal pain upper x
Function kidney decreased x
Abdominal distress x
Upset stomach x
Ketonemia x
Chest discomfort x x x x x x x x x
Azotaemia x
Hepatobiliary disease
Vision blurred
Rigors
Bradycardia x
Neuropathy x x x x x
Respiratory distress x
Tooth abscess x
Reaction gastrointestinal x x x x
Azotemia prerenal x x x x x
Emotional distress x
Sweating increased x x x x x x x x x
White blood cell count increased
Infestation NOS x
Ear and labyrinth disorders x
Oedema aggravated
Vitamin B12 absorption decreased x x
Rhinorrhoea
Epigastric discomfort x x
Appetite absent
Loose stools x
Gastrointestinal tract irritation
Somnolence x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

METFORMIN

Side effects:7
Source:FDA Structured Product Label

metformin

Side effects:13
Source:FDA Structured Product Label

METFORMIN

Side effects:13
Source:FDA Structured Product Label

METFORMIN HYDROCHLORIDE / RATIO-METFORMIN

Side effects:14
Source:Health Canada

METFORMIN

Side effects:14
Source:FDA Structured Product Label

METFORMIN HYDROCHLORIDE / RAN-METFORMIN

Side effects:15
Source:Health Canada

METFORMIN HYDROCHLORIDE / PMS-METFORMIN - TAB 500MG

Side effects:15
Source:Health Canada

METFORMIN HYDROCHLORIDE / CO METFORMIN, 500MG

Side effects:22
Source:Health Canada

METFORMIN HYDROCHLORIDE / NOVO-METFORMIN TAB 850MG

Side effects:22
Source:Health Canada

METFORMIN

Side effects:22
Source:FDA Structured Product Label

METFORMIN

Side effects:24
Source:FDA Structured Product Label

METFORMIN

Side effects:26
Source:FDA Structured Product Label

METFORMIN

Side effects:26
Source:FDA Structured Product Label

METFORMIN

Side effects:26
Source:FDA Structured Product Label

METFORMIN

Side effects:26
Source:FDA Structured Product Label

METFORMIN HYDROCHLORIDE / FORTAMET

Side effects:26
Source:FDA

METFORMIN

Side effects:29
Source:FDA Structured Product Label

METFORMIN HYDROCHLORIDE / GLUMETZA

Side effects:40
Source:FDA

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label