Acitretin
  
Side effects 
	
		
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			Show MedDRA Preferred Terms
		
	
	
| Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 5 | 6 | 
| Hypertriglyceridaemia | 65% |  |  | x | x |  |  |  | 
| Uric acid level increased | 17% |  |  | x |  |  |  |  | 
| Dry eye | 30% |  |  | x |  |  |  |  | 
| Hypercholesterolaemia | 9% |  |  | x |  |  |  |  | 
| White blood cell count decreased | 7% |  |  | x | x |  |  |  | 
| Erectile dysfunction | 1-10% |  |  | x | x |  |  |  | 
| Creatinine increased | 5% |  |  | x | x |  |  |  | 
| Glycosuria | postmarketing, 4% |  |  |  | x | x | x | x | 
| Ketonuria | postmarketing, 3% |  |  |  | x | x | x | x | 
| Proteinuria | postmarketing, 2% |  |  |  | x | x | x | x | 
| Abdominal pain | postmarketing |  |  |  | x | x | x | x | 
| Alopecia | postmarketing, 7-75% |  | x | x | x | x | x | x | 
| Angioedema | postmarketing |  |  |  | x | x | x | x | 
| Anorexia | postmarketing, 1-10% |  |  | x | x | x | x | x | 
| Anus disorder | postmarketing |  |  |  | x | x | x | x | 
| Anxiety | postmarketing |  |  |  |  | x | x | x | 
| Arthralgia | postmarketing |  |  | x | x | x | x | x | 
| Arthritis | postmarketing, 1-10% |  |  | x | x | x | x | x | 
| Back pain | postmarketing, 1-10% |  |  | x | x | x | x | x | 
| Blepharitis | postmarketing |  |  | x | x | x | x | x | 
| Bone disorder | postmarketing |  |  |  |  | x | x | x | 
| Candida infection | postmarketing |  |  |  | x | x | x | x | 
| Chalazion | postmarketing |  |  |  |  | x | x | x | 
| Cheilitis | postmarketing |  | x | x | x | x | x | x | 
| Chest pain | postmarketing |  |  |  | x | x | x | x | 
| Infection | postmarketing |  |  | x | x | x | x | x | 
| Conjunctival haemorrhage | postmarketing |  |  |  |  | x | x | x | 
| Conjunctivitis | postmarketing |  | x |  | x | x | x | x | 
| Constipation | postmarketing |  |  |  | x | x | x | x | 
| Ulcerative keratitis | postmarketing |  | x |  |  | x | x | x | 
| Cough | postmarketing |  |  |  | x | x | x | x | 
| Cyanosis | postmarketing |  |  |  |  | x | x | x | 
| Cyst | postmarketing |  |  |  |  | x | x | x | 
| Deafness | postmarketing |  |  |  | x | x | x | x | 
| Libido decreased | postmarketing |  |  |  |  | x | x | x | 
| Depression | postmarketing |  |  |  | x | x | x | x | 
| Dermatitis | postmarketing |  | x |  | x | x | x | x | 
| Dermatitis exfoliative | postmarketing |  |  |  |  | x | x | x | 
| Scleroderma | postmarketing |  |  |  |  | x | x | x | 
| Diarrhoea | postmarketing |  |  |  | x | x | x | x | 
| Diplopia | postmarketing |  |  |  |  | x | x | x | 
| Dizziness | postmarketing |  |  |  |  | x | x | x | 
| Dysgeusia | postmarketing, 1-10% |  |  | x | x | x | x | x | 
| Dyspepsia | postmarketing |  |  |  | x | x | x | x | 
| Dysuria | postmarketing |  |  |  | x | x | x | x | 
| Ear pain | postmarketing, 1-10% |  |  | x | x | x | x | x | 
| Ectropion | postmarketing |  |  |  |  | x | x | x | 
| Eczema | postmarketing |  |  |  | x | x | x | x | 
| Oedema | postmarketing, 1-10% |  |  | x | x | x | x | x | 
| Epistaxis | postmarketing |  | x | x | x | x | x | x | 
| Oesophagitis | postmarketing |  |  |  |  | x | x | x | 
| Rash | postmarketing |  |  | x | x | x | x | x | 
| Congenital eye disorder | postmarketing |  |  |  | x | x | x | x | 
| Eye disorder | postmarketing |  |  |  | x | x | x | x | 
| Fasting | postmarketing |  |  |  |  | x | x | x | 
| Fatigue | postmarketing, 1-10% |  |  | x | x | x | x | x | 
| Body temperature increased | postmarketing |  |  |  | x | x | x | x | 
| Flushing | postmarketing |  | x |  | x | x | x | x | 
| Furunculosis | postmarketing |  |  |  |  | x | x | x | 
| Gastritis | postmarketing |  |  |  |  | x | x | x | 
| Gastroenteritis | postmarketing |  |  |  |  | x | x | x | 
| Gingival bleeding | postmarketing |  |  |  | x | x | x | x | 
| Gingival hyperplasia | postmarketing |  |  |  |  | x | x | x | 
| Gingivitis | postmarketing |  | x |  | x | x | x | x | 
| Glossitis | postmarketing |  |  |  | x | x | x | x | 
| Headache | postmarketing |  |  |  |  |  | x | x | 
| Haematuria | postmarketing |  |  |  |  | x | x | x | 
| Haemorrhage | postmarketing |  |  | x |  | x | x | x | 
| Haemorrhoids | postmarketing |  |  |  |  | x | x | x | 
| Hepatitis | postmarketing |  | x |  |  | x | x | x | 
| Herpes simplex | postmarketing |  |  |  |  | x | x | x | 
| Hyperaesthesia | postmarketing |  |  | x | x | x | x | x | 
| Hyperostosis | postmarketing, 1-10% |  |  | x |  | x | x | x | 
| Senile ankylosing vertebral hyperostosis | postmarketing |  | x |  | x | x | x | x | 
| Hypersensitivity | postmarketing |  |  |  |  | x | x | x | 
| Hypertrichosis | postmarketing |  |  |  |  | x | x | x | 
| Hypoaesthesia | postmarketing |  |  |  | x | x | x | x | 
| Immune system disorder | postmarketing |  |  |  |  | x | x | x | 
| Intermittent claudication | postmarketing |  |  |  |  | x | x | x | 
| Eye pruritus | postmarketing |  |  |  |  | x | x | x | 
| Jaundice | postmarketing |  | x |  | x | x | x | x | 
| Arthropathy | postmarketing |  |  |  | x | x | x | x | 
| Laryngitis | postmarketing |  |  |  | x | x | x | x | 
| Leukorrhea | postmarketing |  |  |  | x | x | x | x | 
| Breast pain | postmarketing |  |  |  |  | x | x | x | 
| Melaena | postmarketing |  |  |  | x | x | x | x | 
| Hypertonia | postmarketing, 1-10% |  |  | x | x | x | x | x | 
| Myopathy | postmarketing |  |  |  |  | x | x | x | 
| Fungal infection | postmarketing |  |  |  |  | x | x | x | 
| Nail disorder | postmarketing |  |  |  | x | x | x | x | 
| Nausea | postmarketing, 1-10% |  | x | x | x | x | x | x | 
| Nervousness | postmarketing, 1-10% |  |  | x | x | x | x | x | 
| Neuritis | postmarketing |  |  |  |  | x | x | x | 
| Night blindness | postmarketing |  |  |  |  | x | x | x | 
| Otitis externa | postmarketing |  |  |  | x | x | x | x | 
| Otitis media | postmarketing |  |  |  |  | x | x | x | 
| Pain | postmarketing |  |  | x | x | x | x | x | 
| Papilloedema | postmarketing |  |  |  |  | x | x | x | 
| Paraesthesia | postmarketing |  |  |  | x | x | x | x | 
| Paronychia | postmarketing |  | x |  | x | x | x | x | 
| Penis disorder | postmarketing |  |  |  |  | x | x | x | 
| Neuropathy peripheral | postmarketing |  | x |  |  | x | x | x | 
| Pharyngitis | postmarketing |  |  |  | x | x | x | x | 
| Pruritus | postmarketing, 10-50% |  | x | x | x | x | x | x | 
| Benign intracranial hypertension | postmarketing, 1% |  | x | x | x | x | x | x | 
| Psoriasis | postmarketing |  |  |  |  |  | x | x | 
| Purpura | postmarketing |  |  |  | x | x | x | x | 
| Rhinitis | postmarketing |  | x | x | x | x | x | x | 
| Seborrhoeic dermatitis | postmarketing |  |  |  | x | x | x | x | 
| Salivary hypersecretion | postmarketing |  |  |  | x | x | x | x | 
| Sinusitis | postmarketing |  |  |  | x | x | x | x | 
| Skin disorder | postmarketing |  |  |  | x | x | x | x | 
| Skin nodule | postmarketing |  |  |  | x | x | x | x | 
| Skin ulcer | postmarketing |  |  |  | x | x | x | x | 
| Stomatitis | postmarketing |  | x |  | x | x | x | x | 
| Ulcerative stomatitis | postmarketing |  |  |  | x | x | x | x | 
| Cerebrovascular accident | postmarketing |  |  |  |  | x | x | x | 
| Sunburn | postmarketing |  |  |  |  | x | x | x | 
| Sweat gland disorder | postmarketing |  |  |  |  | x | x | x | 
| Tendonitis | postmarketing |  |  |  |  | x | x | x | 
| Thirst | postmarketing |  | x |  | x | x | x | x | 
| Thromboembolism | postmarketing |  |  |  |  | x | x | x | 
| Tinnitus | postmarketing, 1-10% |  |  | x | x | x | x | x | 
| Tongue disorder | postmarketing |  |  |  |  | x | x | x | 
| Urticaria | postmarketing |  |  |  |  | x | x | x | 
| Angiopathy | postmarketing |  |  |  |  | x | x | x | 
| Vulvovaginitis | postmarketing |  | x |  | x | x | x | x | 
| Common wart | postmarketing |  |  |  |  | x | x | x | 
| Weight increased | postmarketing |  |  |  |  | x | x | x | 
| Xerophthalmia | postmarketing |  | x |  | x | x | x | x | 
| Dry mouth | postmarketing |  | x | x | x | x | x | x | 
| Self injurious behaviour | postmarketing |  |  |  |  | x | x | x | 
| Photophobia | postmarketing |  |  | x | x | x | x | x | 
| Pyogenic granuloma | postmarketing |  |  |  | x | x | x | x | 
| Hepatic function abnormal | postmarketing |  |  |  |  | x | x | x | 
| Migraine | postmarketing |  |  |  |  | x | x | x | 
| Alcohol intolerance | postmarketing |  |  |  | x | x | x | x | 
| Skin atrophy | postmarketing |  |  | x | x | x | x | x | 
| Bleeding time prolonged | postmarketing |  |  |  | x | x | x | x | 
| Hair discoloration | postmarketing |  |  |  |  | x | x | x | 
| Impaired healing | postmarketing |  |  |  | x | x | x | x | 
| Skin hypertrophy | postmarketing |  |  |  | x | x | x | x | 
| Intracranial pressure increased | postmarketing |  | x |  |  | x | x | x | 
| Muscular weakness | postmarketing |  |  |  | x | x | x | x | 
| Eye pain | postmarketing |  |  |  | x | x | x | x | 
| Dry skin | postmarketing |  |  | x | x | x | x | x | 
| Skin irritation | postmarketing |  |  |  |  | x | x | x | 
| Acute myocardial infarction | postmarketing |  |  |  |  | x | x | x | 
| Photosensitivity reaction | postmarketing |  | x |  | x | x | x | x | 
| Skin fissures | postmarketing |  | x |  | x | x | x | x | 
| Vaginitis atrophic | postmarketing |  |  |  |  | x | x | x | 
| Malaise | postmarketing |  |  |  | x | x | x | x | 
| Myalgia | postmarketing |  |  | x | x | x | x | x | 
| Increased appetite | postmarketing, 1-10% |  |  | x | x | x | x | x | 
| Rectal tenesmus | postmarketing |  |  |  | x | x | x | x | 
| Rash erythematous | postmarketing |  |  |  | x | x | x | x | 
| Skin odour abnormal | postmarketing |  |  |  | x | x | x | x | 
| Tongue ulceration | postmarketing |  |  |  | x | x | x | x | 
| Peripheral ischaemia | postmarketing |  |  |  |  | x | x | x | 
| Urine abnormality | postmarketing |  |  |  | x | x | x | x | 
| Saliva altered | postmarketing |  |  |  | x | x | x | x | 
| Psoriasis flare-up | postmarketing |  |  |  |  | x | x | x | 
| Hair texture abnormal | postmarketing |  | x |  | x | x | x | x | 
| Bullous eruption | postmarketing |  | x |  | x | x | x | x | 
| Lacrimation abnormal NOS | postmarketing |  |  | x | x | x | x | x | 
| Skin exfoliation | postmarketing |  |  |  | x | x | x | x | 
| Dermatitis psoriasiform | postmarketing |  |  |  |  | x | x | x | 
| Olecranon bursitis | postmarketing |  |  |  | x | x | x | x | 
| Madarosis | postmarketing |  |  |  |  | x | x | x | 
| Ceruminosis | postmarketing |  |  |  | x | x | x | x | 
| Adenocarcinoma pancreas | postmarketing |  |  |  |  | x | x | x | 
| Capillary leak syndrome | postmarketing |  |  |  |  | x | x | x | 
| Vision blurred | postmarketing, 1- 10% |  | x | x | x | x | x | x | 
| Sticky skin | postmarketing |  | x | x | x | x | x | x | 
| Influenza-like symptoms | postmarketing |  |  |  |  | x | x | x | 
| Skin thinness | postmarketing |  | x |  |  | x | x | x | 
| Suicidal ideation | postmarketing |  |  |  |  | x | x | x | 
| Rigors | postmarketing |  |  | x | x | x | x | x | 
| Laboratory test abnormal | postmarketing |  |  |  |  | x | x |  | 
| Skin fragility | postmarketing |  |  |  |  | x | x | x | 
| Monocyte count decreased | postmarketing |  |  |  |  |  |  | x | 
| Gait disturbance | postmarketing |  |  |  | x | x | x | x | 
| Sodium high | postmarketing |  |  |  |  |  |  | x | 
| Hot flush | postmarketing |  |  |  | x | x | x | x | 
| Carcinoma of lung | postmarketing |  |  |  |  | x | x | x | 
| Sweating increased | postmarketing |  |  |  | x | x | x | x | 
| Acne | postmarketing |  |  |  | x | x | x | x | 
| White blood cell count increased | postmarketing |  |  |  |  | x | x | x | 
| Decreased night vision | postmarketing, 1% |  |  | x | x | x | x | x | 
| Hyperkeratosis | postmarketing |  |  |  |  | x | x | x | 
| Insomnia | postmarketing, 1-10% |  |  | x | x | x | x | x | 
| Dysphonia | postmarketing |  |  |  | x | x | x | x | 
| Ageusia | postmarketing |  |  |  | x | x | x | x | 
| Somnolence | postmarketing |  |  |  | x | x | x | x | 
| Congenital anomaly |  |  |  |  | x |  |  |  | 
| Alcoholism |  |  | x |  |  |  |  |  | 
| Balanoposthitis |  |  |  |  | x |  |  |  | 
| Cytopenia |  |  |  | x |  |  |  |  | 
| Diabetes mellitus |  |  | x |  |  |  |  |  | 
| Gastrointestinal disorder |  |  | x |  |  |  |  |  | 
| Hordeolum |  |  |  | x | x |  |  |  | 
| Hyperlipidaemia |  |  |  | x |  |  |  |  | 
| Hypervitaminosis A |  |  | x | x | x | x | x | x | 
| Iritis |  |  |  | x |  |  |  |  | 
| Cramps of lower extremities |  |  |  |  | x |  |  |  | 
| Obesity |  |  | x |  |  |  |  |  | 
| Pancreatitis |  |  |  | x | x |  |  |  | 
| Retinal haemorrhage |  |  |  | x |  |  |  |  | 
| Scotoma |  |  |  | x |  |  |  |  | 
| Erythema |  |  | x | x | x |  |  |  | 
| Urinary tract infection |  |  |  | x |  |  |  |  | 
| Vasculitis |  |  |  |  | x |  |  |  | 
| Vomiting |  |  | x |  |  |  |  |  | 
| Weight decreased |  |  |  | x |  |  |  |  | 
| Oedema peripheral |  |  | x |  |  |  |  |  | 
| Cataract |  |  |  |  | x |  |  |  | 
| High density lipoprotein decreased |  |  |  |  | x |  |  |  | 
| Bone pain |  |  | x |  | x |  |  |  | 
| Alanine aminotransferase increased |  |  |  |  | x |  |  |  | 
| Decreased tolerance |  |  |  | x |  |  |  |  | 
| Scab |  |  |  | x |  |  |  |  | 
| Visual acuity reduced |  |  |  | x |  |  |  |  | 
| Eye irritation |  |  |  | x |  |  |  |  | 
| Diabetic |  |  |  | x |  |  |  |  | 
| Redness |  |  |  | x |  |  |  |  | 
| Photosensitivity |  |  |  | x |  |  |  |  | 
| Visual disturbance |  |  | x |  |  |  |  |  | 
| Lip dry |  |  |  | x | x |  |  |  | 
| Eyebrow loss of |  |  |  | x |  |  |  |  | 
| Febrile neutropenia |  |  |  | x |  |  |  |  | 
| Hepatitis F |  |  |  |  | x |  |  |  | 
| Posterior subcapsular cataract |  |  |  | x |  |  |  |  | 
| Raised liver function tests |  |  |  | x |  |  |  |  | 
	 
 
  Indications
	Information about indications was extracted from the indications and usage sections of the labels.
	
 
	  
	  
		| Side effects: | 40 | 
|---|
		| Source: | Medsafe | 
|---|
		 
	  
	  
		| Side effects: | 67 | 
|---|
		| Source: | BC Cancer | 
|---|
		 
	  
	  
		| Side effects: | 130 | 
|---|
		| Source: | Health Canada | 
|---|
		 
	  
	  
		| Side effects: | 184 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 186 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 187 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
  
 
  
	Color scheme:
	  
	  standard – alternative
	  
	
	
|  |  | 100% | 
|  |  | 75% | 
|  |  | 50% | 
|  |  | 10% | 
|  |  | frequent (1% to 100%) | 
|  |  | infrequent (0.1% to 1%) | 
|  |  | rare (<0.1%) | 
|  |  | postmarketing | 
|  |  | 0% | 
|  |  | no frequency information | 
|  |  | not found on label |