Stavudine
  
Side effects 
	
		
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| Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 
| Headache | 49% - 54% |  |  | x | x | x | x | x | x | x | x | x | 
| Neuropathy | 39% - 52% |  | x | x | x | x | x | x | x | x | x | x | 
| Diarrhoea | common, 44% - 50% |  |  | x | x | x | x | x | x | x | x | x | 
| Nausea | common, 39% - 44% |  |  | x | x | x | x | x | x | x | x | x | 
| Vomiting | uncommon, 39% - 44% |  |  | x | x | x | x | x | x | x | x | x | 
| Neurological symptom | common, 39% - 52% |  |  | x | x | x | x | x | x | x | x | x | 
| Rash | common, 35% - 40% |  |  | x | x | x | x | x | x | x | x | x | 
| Dyspepsia | common |  |  |  |  |  |  |  |  | x | x | x | 
| Fatigue | common |  |  |  |  |  |  |  |  | x |  | x | 
| Neuritis | common |  |  |  |  |  |  |  |  | x |  | x | 
| Paraesthesia | common |  |  |  |  |  |  |  |  | x |  | x | 
| Pruritus | common |  |  |  |  |  |  |  |  | x | x | x | 
| Asymptomatic hyperlactatemia | common |  |  |  |  |  |  |  |  |  |  | x | 
| Anxiety | uncommon |  |  |  |  |  |  |  |  |  |  | x | 
| Arthralgia | uncommon |  |  |  |  |  |  |  |  |  | x | x | 
| Gynaecomastia | uncommon |  |  |  |  |  |  |  |  |  |  | x | 
| Jaundice | uncommon |  |  |  |  |  |  |  |  |  |  | x | 
| Nervous system disorder | uncommon |  |  |  |  |  |  |  |  |  |  | x | 
| Urticaria | uncommon |  |  |  |  |  |  |  |  |  |  | x | 
| Mood swings | uncommon |  |  |  |  |  |  |  |  |  |  | x | 
| Malnutrition | uncommon |  |  |  |  |  |  |  |  |  |  | x | 
| Hepatobiliary disease | uncommon |  |  |  |  |  |  |  |  |  |  | x | 
| Abdominal pain | postmarketing, common |  | x | x | x | x | x | x | x | x | x | x | 
| Lactic acidosis | postmarketing, uncommon |  |  |  |  |  | x | x | x |  |  | x | 
| Anaemia | postmarketing, rare |  | x | x | x | x | x | x | x | x | x | x | 
| Anorexia | postmarketing, uncommon |  | x | x | x | x | x | x | x | x | x | x | 
| Asthenia | very rare — uncommon |  | x | x | x | x | x | x | x | x | x | x | 
| Diabetes mellitus | very rare, postmarketing |  | x | x | x | x | x | x | x |  | x | x | 
| Body temperature increased | postmarketing |  | x | x | x | x | x | x | x | x | x |  | 
| Blood disorder | postmarketing |  | x |  | x | x | x | x | x | x | x |  | 
| Hepatitis | postmarketing, uncommon |  | x | x | x | x | x | x | x | x | x | x | 
| Hyperglycaemia | postmarketing, rare |  | x | x | x | x | x | x | x |  | x | x | 
| Hypersensitivity | postmarketing |  | x | x | x | x | x | x | x | x | x |  | 
| Leukopenia | postmarketing |  | x | x | x | x | x | x | x | x | x |  | 
| Lipodystrophy | postmarketing, common |  |  |  |  |  | x | x | x | x |  | x | 
| Metabolic disorder | postmarketing |  | x | x | x | x | x | x | x |  | x |  | 
| Neutropenia | very rare, postmarketing |  |  |  |  |  | x | x | x | x |  | x | 
| Pancreatitis | postmarketing, uncommon |  |  |  |  |  | x | x | x |  |  | x | 
| Neuropathy peripheral | postmarketing, common |  | x | x | x | x | x | x | x | x | x | x | 
| Thrombocytopenia | very rare, postmarketing |  | x | x | x | x | x | x | x | x | x | x | 
| Chills | postmarketing |  | x | x | x | x | x | x | x | x | x |  | 
| Hepatic failure | very rare, postmarketing |  | x | x | x | x | x | x | x | x | x | x | 
| Myalgia | postmarketing, uncommon |  | x | x | x | x | x | x | x | x | x | x | 
| Hepatotoxicity | postmarketing |  | x | x | x | x | x | x | x | x | x |  | 
| Insomnia | postmarketing |  | x | x | x | x | x | x | x | x | x | x | 
| Symptomatic hyperlactatemia | very rare, postmarketing |  | x | x | x | x | x | x | x | x | x | x | 
| Lipoatrophy | postmarketing, common |  |  |  |  |  | x | x | x |  |  | x | 
| Hepatic steatosis | postmarketing, rare |  | x | x | x | x | x | x | x | x | x | x | 
| Mental disorder | very rare |  |  |  |  |  |  |  |  |  |  | x | 
| Connective tissue disorder | very rare |  |  |  |  |  |  |  |  |  |  | x | 
| Endocrine disorder | very rare |  |  |  |  |  |  |  |  |  |  | x | 
| Gastrointestinal disorder | very rare |  |  |  |  |  |  |  |  |  | x | x | 
| Unspecified disorder of skin and subcutaneous tissue | very rare |  |  |  |  |  |  |  |  |  |  | x | 
| Lactic acidosis syndrome | very rare |  |  |  |  |  |  |  |  | x |  | x | 
| Autoimmune disorder |  |  |  |  |  |  |  |  |  |  |  | x | 
| Back pain |  |  |  |  |  |  |  |  |  |  | x |  | 
| Bronchitis |  |  |  |  |  |  |  |  |  |  | x |  | 
| Conjunctivitis |  |  |  |  |  |  |  |  |  |  | x |  | 
| Constipation |  |  |  |  |  |  |  |  |  |  | x |  | 
| Depression |  |  |  |  |  |  |  |  |  | x | x |  | 
| Dizziness |  |  |  |  |  |  |  |  |  | x | x | x | 
| Dysgeusia |  |  |  |  |  |  |  |  |  |  | x |  | 
| Dysuria |  |  |  |  |  |  |  |  |  |  | x |  | 
| Eructation |  |  |  |  |  |  |  |  |  |  | x |  | 
| Flatulence |  |  |  |  |  |  |  |  |  |  | x |  | 
| Basedow's disease |  |  |  |  |  |  |  |  |  |  |  | x | 
| Guillain-Barre syndrome |  |  |  |  |  |  |  |  |  |  |  | x | 
| Haematuria |  |  |  |  |  |  |  |  |  |  | x |  | 
| Hepatitis B |  |  |  |  |  |  |  |  |  | x |  |  | 
| Hepatomegaly |  |  |  |  |  |  | x | x | x |  |  | x | 
| Hyperbilirubinaemia |  |  |  |  |  |  |  |  |  |  | x |  | 
| Hypercholesterolaemia |  |  |  |  |  |  |  |  |  |  |  | x | 
| Hypertriglyceridaemia |  |  |  |  |  |  |  |  |  |  |  | x | 
| Hypertrophy of breast |  |  |  |  |  |  |  |  |  |  |  | x | 
| Inflammation |  |  |  |  |  |  |  |  |  |  |  | x | 
| Influenza |  |  |  |  |  |  |  |  |  |  | x |  | 
| Insulin resistance |  |  |  |  |  |  |  |  |  |  |  | x | 
| Calculus of kidney |  |  |  |  |  |  |  |  |  |  | x |  | 
| Liver disorder |  |  |  |  |  |  |  |  |  | x |  |  | 
| Lung disorder |  |  |  |  |  |  |  |  |  |  | x |  | 
| Fungal infection |  |  |  |  |  |  |  |  |  |  | x |  | 
| Numbness |  |  | x | x | x | x |  |  |  | x | x |  | 
| Opportunistic infection |  |  |  |  |  |  |  |  |  |  |  | x | 
| Osteonecrosis |  |  |  |  |  |  |  |  |  |  |  | x | 
| Pain |  |  | x | x | x | x |  |  |  | x | x |  | 
| Pharyngitis |  |  |  |  |  |  |  |  |  |  | x |  | 
| Rhinitis |  |  |  |  |  |  |  |  |  |  | x |  | 
| Sinusitis |  |  |  |  |  |  |  |  |  |  | x |  | 
| Sweating |  |  |  |  |  |  |  |  |  |  | x |  | 
| Urinary tract infection |  |  |  |  |  |  |  |  |  |  | x |  | 
| Weight decreased |  |  |  |  |  |  |  |  |  |  | x |  | 
| Dry mouth |  |  |  |  |  |  |  |  |  |  | x |  | 
| Hepatic function abnormal |  |  |  |  |  |  |  |  |  |  | x |  | 
| Mouth ulceration |  |  |  |  |  |  |  |  |  |  | x |  | 
| Peripheral sensory neuropathy |  |  | x | x | x | x |  |  |  | x | x |  | 
| Accidental injury |  |  |  |  |  |  |  |  |  |  | x |  | 
| Dry skin |  |  |  |  |  |  |  |  |  |  | x |  | 
| Polyneuropathy |  |  |  |  |  |  |  |  |  |  |  | x | 
| Haemoglobin decreased |  |  |  |  |  |  |  |  |  |  |  | x | 
| Thinking abnormal |  |  |  |  |  |  |  |  |  | x |  | x | 
| Abnormal dreams |  |  |  |  |  |  |  |  |  | x |  | x | 
| Buffalo hump |  |  |  |  |  |  |  |  |  |  |  | x | 
| Cough increased |  |  |  |  |  |  |  |  |  |  | x |  | 
| Stillbirth |  |  |  |  |  |  |  |  |  |  |  | x | 
| Acne |  |  |  |  |  |  |  |  |  |  | x |  | 
| Hyperlactacidaemia |  |  |  |  |  |  |  |  |  |  |  | x | 
| Blood and lymphatic system disorders |  |  |  |  |  |  |  |  |  |  |  | x | 
| Fat redistribution |  |  | x | x | x | x |  |  |  | x | x |  | 
| Mitochondrial toxicity |  |  |  |  |  |  |  |  |  |  |  | x | 
| Respiratory failure |  |  |  |  |  |  |  |  |  |  |  | x | 
| Tingling sensation |  |  | x | x | x | x |  |  |  | x | x |  | 
| Somnolence |  |  |  |  |  |  |  |  |  | x |  | x | 
	 
 
  Indications
	Information about indications was extracted from the indications and usage sections of the labels.
	
 
	  
	  
		| Side effects: | 27 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 32 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 33 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 33 | 
|---|
		| Source: | FDA | 
|---|
		 
	  
	  
		| Side effects: | 34 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 34 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 34 | 
|---|
		| Source: | FDA Structured Product Label | 
|---|
		 
	  
	  
		| Side effects: | 45 | 
|---|
		| Source: | FDA | 
|---|
		 
	  
	  
		| Side effects: | 66 | 
|---|
		| Source: | Health Canada | 
|---|
		 
	  
	  
		| Side effects: | 70 | 
|---|
		| Source: | EMA | 
|---|
		 
	  
  
 
  
	Color scheme:
	  
	  standard – alternative
	  
	
	
|  |  | 100% | 
|  |  | 75% | 
|  |  | 50% | 
|  |  | 10% | 
|  |  | frequent (1% to 100%) | 
|  |  | infrequent (0.1% to 1%) | 
|  |  | rare (<0.1%) | 
|  |  | postmarketing | 
|  |  | 0% | 
|  |  | no frequency information | 
|  |  | not found on label |