| Side effect | Data for drug | Placebo | Labels | 
|  | 1 | 2 | 3 | 4 | 5 | 6 | 7 | 8 | 9 | 10 | 11 | 12 | 13 | 14 | 15 | 16 | 17 | 18 | 19 | 20 | 
| Injection site reaction | 59% | 24% |  |  |  |  |  |  |  | x |  |  |  |  | x | x |  | x |  | x | x | x | 
| Injection site bruising | postmarketing, 16% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Tingling sensation | common, 1% - 14% | 1% - 3% |  |  | x |  | x | x | x | x |  |  | x | x | x | x |  | x | x | x | x | x | 
| Nausea | common, 11% - 14% | 7% - 11.3% |  | x |  |  |  | x | x | x |  | x |  | x | x | x |  |  | x | x | x | x | 
| Vomiting | common, 11% - 14% | 7% - 11.3% |  | x |  |  | x |  | x | x | x | x |  | x | x | x |  |  | x | x | x | x | 
| Dizziness | common, 1% - 12% | 0.9% - 4% |  | x | x |  | x | x | x | x | x | x |  | x | x | x |  |  | x | x | x | x | 
| Flushing | 1% - 7% | 1% - 2% |  |  | x |  |  |  |  | x | x | x |  | x | x | x |  | x | x | x | x | x | 
| Sensation of pressure | 1% - 7% | 1% - 2% |  |  |  |  |  |  |  | x |  |  |  |  | x | x |  |  |  |  | x | x | 
| Injection site haemorrhage | postmarketing, 6% |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Injection site pain | postmarketing — 6% |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  | 
| Neck pain | 3% - 5% | 0% - 1% |  |  |  |  |  |  |  | x |  |  |  |  | x | x |  | x | x | x | x | x | 
| Diarrhoea | infrequent, frequent |  |  |  |  |  | x | x | x |  |  |  |  | x |  |  | x | x | x | x | x | x | 
| Hypoaesthesia | common |  |  |  |  |  |  |  |  |  | x | x |  |  | x |  |  |  |  |  |  |  | 
| Numbness | frequent, 2% - 5% | 1% - 2% |  |  |  |  | x | x | x | x |  |  | x | x | x | x | x | x | x | x | x | x | 
| Palpitations | very rare — 1% | 1% | x | x | x |  | x | x | x |  | x | x | x | x | x | x | x | x | x | x | x | x | 
| Sinusitis | frequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Tinnitus | frequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Burning sensation | frequent, 0.4% - 7% | 0% - 1% |  | x | x |  | x | x | x | x |  |  | x | x | x | x | x | x | x | x | x | x | 
| Photophobia | infrequent, frequent |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | x | x | x | x | x | x | 
| Sensory disturbance | common |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  | 
| Abdominal discomfort | frequent, 3% | 3% |  |  |  |  | x | x | x |  |  |  |  | x | x | x |  | x | x | x | x | x | 
| Sensation of heat | common |  |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  | 
| Chest discomfort | 5% | 1% |  |  |  |  |  |  |  | x |  |  |  |  |  | x |  | x | x | x | x | x | 
| Stiffness | infrequent, 3% - 5% | 0% - 1% |  |  |  |  |  |  |  | x |  |  |  |  | x | x |  | x | x | x | x | x | 
| Blood pressure increased | frequent |  | x | x |  | x |  |  |  | x |  |  |  |  |  | x | x | x | x | x | x | x | 
| Phonophobia | frequent |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  | x | x | x | x | x | x | 
| Asthenia | common, 0.4% - 5% | 1% |  |  | x |  | x | x | x | x | x | x | x | x | x | x |  | x | x | x | x | x | 
| Dermatitis contact | 4% |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Application site pain | 4% |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Drowsiness | common, 3% | 1% - 2% |  |  | x |  | x | x | x | x | x | x |  | x | x | x |  |  | x | x | x | x | 
| Paraesthesia | infrequent — 1% - 5% | 0% - 2% | x |  |  | x | x | x | x | x |  | x | x | x | x | x |  |  | x | x | x | x | 
| Muscle spasms | 3% | 0% |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Chest tightness | 3% | 1% |  |  |  |  |  |  |  | x |  |  |  |  |  | x |  |  |  |  | x | x | 
| Throat sore | 0.8% - 3% | 1% - 0.9% |  | x |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Chest pain | 1% - 3% | 1% | x |  |  | x |  |  |  |  |  |  |  | x | x |  |  |  | x | x | x | x | 
| Fatigue | common, 0.4% - 9.5% | 1% - 5.1% | x |  | x |  | x | x | x |  | x | x | x | x | x |  |  | x | x | x |  |  | 
| Headache | 1% - 2% | 1% |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x |  | 
| Pain | postmarketing — 1% - 8% | 1% - 4% |  |  |  |  |  |  |  |  |  | x |  |  |  | x |  |  | x | x | x | x | 
| Sweating | rare — 0.6% - 2% | 0.4% - 1% |  |  |  |  | x | x | x | x |  |  |  | x | x | x | x | x | x | x | x | x | 
| Malaise | 2% - 9.5% | 1% - 5.1% | x |  |  |  | x | x | x |  |  |  |  | x | x |  |  |  | x | x |  |  | 
| Myalgia | frequent, 0.1% - 2% | 0.3% - 1% |  |  |  |  | x | x | x | x |  |  |  | x | x | x | x | x | x | x | x | x | 
| Discomfort | 2% - 3.8% | 0% - 2.4% |  | x |  | x | x | x | x | x |  |  | x | x |  | x |  | x | x | x | x | x | 
| Feeling strange | 0% - 2% | 0% - 1% |  |  |  |  |  |  |  | x |  |  |  |  | x | x |  | x | x | x | x | x | 
| Pain in jaw | 1% - 3% | 1% | x | x |  | x |  |  |  | x |  |  |  |  |  | x |  |  | x | x | x | x | 
| Chest pressure | 2% | 1% |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x | 
| Musculoskeletal pain | 0.4% - 2.3% | 0.7% |  |  |  |  | x | x | x |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Viral infection | 0.1% - 1.1% | 0.3% |  |  |  |  | x | x | x |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Feeling cold | 1% | 1% |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Muscle atrophy | 0.4% - 1.4% |  |  |  |  |  | x | x | x |  |  |  |  | x |  |  |  | x | x | x | x | x | 
| Arrhythmia | very rare — infrequent |  | x | x | x | x |  |  |  | x | x | x | x |  |  | x | x | x | x | x | x | x | 
| Sinus arrhythmia | infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Asthma | postmarketing — infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Confusional state | infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Constipation | rare, infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Dysphagia | rare — 1% | 0% |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | x | 
| Dysarthria | rare, infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Dysgeusia | infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Dysmenorrhoea | rare, infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Ear pain | rare, infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Facial pain | rare, infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Body temperature increased | rare, infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Gastrooesophageal reflux disease | rare, infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Hypertension | infrequent, 1% | 0% |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  | x | 
| Hypotension | very rare — 1% | 0% | x | x | x |  |  |  |  |  | x | x | x |  | x | x | x | x | x | x | x | x | 
| Metrorrhagia | infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Cramp muscle | rare — frequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Pallor | rare — 1% | 0% |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | x | 
| Supraventricular extrasystoles | infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Shivering | infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Sleep disturbance | rare, infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Syncope | infrequent — 1% | 0% |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | x | 
| Tachycardia | very rare — 1% | 0% |  |  | x |  |  |  |  |  | x | x | x |  | x | x | x | x | x | x | x | x | 
| Thirst | infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Tremor | very rare — infrequent |  | x | x |  |  | x | x | x |  | x | x |  | x | x | x | x | x | x | x | x | x | 
| Chills | infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Monoplegia | rare, infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Ventricular extrasystoles | infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Heat intolerance | infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Tenderness | infrequent, 3% | 0% |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | x | 
| Euphoric mood | rare, infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Skin tenderness | rare, infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Fluid retention | infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Eruption | infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Extrasystoles | infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Lacrimation | rare, infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Coordination abnormal | infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Electrocardiogram change | infrequent, 0% | 0% |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x |  |  | 
| Vertigo | 1% - 12% | 1% - 4% | x | x |  |  | x | x | x | x |  |  |  | x | x | x |  |  | x | x | x | x | 
| Abdominal distension | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Aggression | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Anaphylactic shock | very rare, postmarketing |  |  |  | x |  |  |  |  |  | x | x | x |  | x |  |  | x | x | x | x | x | 
| Anaemia | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Haemolytic anaemia | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Angina pectoris | very rare, rare |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | x | x | x | x | 
| Prinzmetal angina | postmarketing |  | x | x |  | x |  |  |  | x |  |  |  |  |  | x |  | x | x | x | x | x | 
| Angioedema | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Anxiety | rare, frequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Atherosclerosis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Atrial fibrillation | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Back pain | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Bronchospasm | postmarketing |  |  |  |  |  |  |  |  | x |  |  |  |  |  | x |  | x | x | x | x | x | 
| Bronchitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Cluster headache | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  | 
| Colitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Infection | rare, 0.6% - 1.4% | 0.6% |  |  |  |  |  | x | x |  |  |  | x | x |  |  | x | x | x | x | x | x | 
| Conjunctivitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Contusion | postmarketing, rare |  |  |  |  | x |  |  |  | x |  |  |  |  |  | x | x | x | x | x | x | x | 
| Cough | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Cyanosis | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Cystitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Deafness | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Dehydration | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Depressive disorder | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Drug abuse | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Dyspnoea | postmarketing — 1% | 0% |  |  |  |  |  |  |  |  | x | x |  | x | x | x | x | x | x | x | x | x | 
| Dysuria | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Eczema | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Oedema | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Endometriosis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Eructation | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Rash | postmarketing, infrequent |  |  |  |  |  |  |  |  |  | x |  |  | x | x | x | x | x | x | x | x | x | 
| Eye haemorrhage | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Facial paralysis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Flatulence | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Gastritis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Gastroenteritis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Gastrointestinal haemorrhage | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Globus hystericus | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Hallucination | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Block heart | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Haematemesis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Haematoma | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Haematuria | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Herpes NOS | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Hiccups | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Hunger | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Hyperaesthesia | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Hypersensitivity | very rare — frequent |  | x | x | x |  |  |  |  | x | x | x | x | x | x | x | x | x | x | x | x | x | 
| Hypothyroidism | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Hysteria | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Inflammation | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Influenza | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Intestinal obstruction | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Keratitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Calculus of kidney | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Renal failure acute | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Melaena | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Meniere's disease | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Muscle rigidity | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Myopathy | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Mydriasis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Neuralgia | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Neurosis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Nodule | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Pancreatitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Pancytopenia | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Panic disorder | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Peptic ulcer | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Phlebitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Pituitary tumour | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Pruritus | postmarketing — infrequent |  |  |  |  | x |  |  |  |  | x |  |  |  | x | x | x | x | x | x | x | x | 
| Pulmonary embolism | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Retinal artery occlusion | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Seborrhoeic dermatitis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Convulsion | very rare, rare |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x | x | x |  |  | 
| Shock | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Salivary hypersecretion | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Skin wrinkling | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Cerebrovascular accident | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x |  | x | x | x | x | x | 
| Subarachnoid haemorrhage | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Suicide | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Sunburn | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Swelling | postmarketing — infrequent |  |  |  |  |  |  |  |  | x |  |  |  | x |  | x | x | x | x | x | x | x | 
| Tetany | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Thrombocytopenia | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Thrombophlebitis | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Thrombosis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Toothache | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Erythema | postmarketing, infrequent |  |  |  |  |  |  |  |  | x | x |  |  |  | x | x | x | x | x | x | x | x | 
| Urethritis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Pollakiuria | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  | 
| Urticaria | postmarketing |  |  |  |  |  |  |  |  |  | x |  |  | x | x | x |  | x | x | x | x | x | 
| Vasculitis | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Vasodilation | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  | 
| Vision decreased | very rare, rare |  |  |  | x |  | x | x | x |  | x | x | x | x | x |  | x | x | x | x | x | x | 
| Weight decreased | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Dry mouth | postmarketing |  |  |  |  |  | x | x | x |  |  |  |  | x |  |  |  | x | x | x | x | x | 
| Yawning | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Polydipsia | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Agitation | rare, infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Apathy | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Breast discharge | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Migraine | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Allergic cutaneous angiitis | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Swelling face | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x | 
| Intracranial pressure increased | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Myocardial ischaemia | rare |  | x | x |  | x | x | x | x | x |  |  | x | x |  | x | x | x | x | x | x | x | 
| Eye pain | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Optic ischaemic neuropathy | postmarketing |  |  |  |  |  |  |  |  |  |  |  | x |  |  | x |  | x | x | x | x | x | 
| Intervertebral disc disorder | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Colitis ischaemic | very rare, postmarketing |  |  |  | x |  |  |  |  |  | x | x | x |  | x |  |  | x | x | x | x | x | 
| Abdominal aortic aneurysm | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Diplegia | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Muscle stiffness | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Muscle twitching | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Decreased appetite | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Retching | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Menstrual cycle abnormal | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Speech impairment NOS | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Memory impairment | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Motor dysfunction | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Hypervigilance | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Eye irritation | rare, infrequent |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Pulse abnormal | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Cyanosis peripheral | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | x | 
| Galactorrhoea | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Skin exfoliation | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Personality change | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Salivary gland swelling | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Skin tightness | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Muscle fatigue | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Rectal haemorrhage | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Walking disability | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Induration | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x | 
| Redness | postmarketing |  |  |  |  | x |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x | 
| Anaphylactoid reaction | postmarketing |  |  |  |  | x |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Phobia | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Photosensitivity | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Dysaesthesia | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Skin scaly | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Bradycardia | very rare — 1% | 0% |  |  | x |  |  |  |  |  | x | x | x |  | x | x | x | x | x | x | x | x | 
| Blindness | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Lymphadenopathy | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Hemiplegia transient | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Paralysis | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Feeling hot and cold | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Detachment psychological | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Dystonic reaction | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x |  |  | 
| Visual disturbance | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Thyrotropin high | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Stinging | postmarketing, infrequent |  |  |  | x |  |  |  |  | x |  |  |  |  |  | x |  | x | x | x | x | x | 
| Gastrointestinal pain | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Serotonin syndrome | postmarketing |  | x | x |  | x |  |  |  | x |  |  |  |  |  | x |  | x | x | x | x | x | 
| Radiculopathy | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Intoxication | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Eye oedema | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Dyspeptic signs and symptoms | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Raised liver function tests | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Cardiomyopathy | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Cerebral ischaemia | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Oral pruritus | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Dysphasia | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Respiration abnormal | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Lipohypertrophy | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x | 
| Lipoatrophy | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x | 
| Voice disturbance | rare |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | x | 
| Retinal vein thrombosis | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Temporal arteritis | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  | x | x | x | x | x | 
| Subcutaneous bleeding | postmarketing |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  | x | x | 
| Unspecified visual loss | very rare, postmarketing |  |  |  | x |  | x | x | x |  | x | x | x | x | x |  |  | x | x | x | x | x | 
| Arteriospasm coronary | very rare |  |  |  | x |  | x | x | x |  | x | x | x | x |  |  |  | x | x | x |  |  | 
| Diplopia | very rare |  |  |  | x |  | x | x | x |  | x | x | x | x | x |  |  |  |  |  |  |  | 
| Myocardial infarction | very rare |  | x | x | x | x | x | x | x | x | x | x | x | x | x | x |  | x | x | x |  |  | 
| Nystagmus | very rare |  |  |  | x |  | x | x | x |  | x | x | x | x | x |  |  |  |  |  |  |  | 
| Scotoma | very rare |  |  |  | x |  | x | x | x |  | x | x | x | x | x |  |  |  |  |  |  |  | 
| Photopsia | very rare |  |  |  | x |  | x | x | x |  | x | x | x | x | x |  |  |  |  |  |  |  | 
| Cutaneous hypersensitivity | very rare |  |  |  | x |  |  |  |  |  | x | x | x |  | x |  |  |  |  |  |  |  | 
| Abdominal pain |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Arthralgia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Arthritis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Blister |  |  |  |  |  | x |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Breast cancer |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Breast feeding |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Breast swelling |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Transient ischaemic attack |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Connective tissue disorder |  |  |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  | 
| Cyst |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Epilepsy |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Epistaxis |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Extrapyramidal disorder |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Eye disorder |  |  |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  | 
| Gastrointestinal disorder |  |  |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  | 
| Blood disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Haemorrhage |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | x | x | x | x | x | 
| Hyperglycaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Hypertensive crisis |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Hypoglycaemia |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Immune system disorder |  |  |  |  |  |  |  |  |  |  | x | x | x |  |  |  |  |  |  |  |  |  | 
| Infarction |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Ischaemia |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Eye pruritus |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Mediastinal disorder |  |  |  |  |  |  |  |  |  |  | x | x |  |  |  |  |  |  |  |  |  |  | 
| Movement disorder |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Nervous system disorder |  |  |  |  |  |  |  |  |  |  | x | x | x |  |  |  |  |  |  |  |  |  | 
| Otitis externa |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Pregnancy |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Retinal vascular occlusion |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Angiopathy |  |  |  |  |  |  |  |  |  |  | x | x | x |  |  |  |  |  |  |  |  |  | 
| Venous thrombosis |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Ventricular fibrillation |  |  |  |  |  |  | x | x | x |  |  |  | x | x |  |  |  | x | x | x |  |  | 
| Ventricular tachycardia |  |  |  |  |  |  | x | x | x |  |  |  | x | x |  |  |  | x | x | x |  |  | 
| Disorder sight |  |  |  |  | x |  | x | x | x |  | x | x | x | x | x |  |  |  |  |  |  |  | 
| Weight increased |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Urogenital disorder |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Vasospasm |  |  | x | x |  | x |  |  |  | x |  |  | x |  |  | x |  |  |  |  |  |  | 
| Akinesia |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Lower respiratory tract infection |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Skin breakdown |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Liver function test abnormal |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x |  |  | 
| Skin irritation |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Abortion |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Allergic contact dermatitis |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Lightheadedness |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Bradycardia-tachycardia syndrome |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Choreoathetoid movements |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Head pressure |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Taste bitter |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Cerebellar infarction |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Heart rate irregular |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Burning tongue |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Parkinsonism |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Musculoskeletal deformity |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Atrophy |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Akathisia |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  | 
| Warmth |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hypertensive episode |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Numbness of tongue |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Localized exfoliation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x |  |  | 
| Application site irritation |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Neck tightness |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Mass |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  | x | x | x | x | x | 
| Ear infection |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Application site pruritus |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Lymphocyte count decreased |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  | 
| Redness of face |  |  |  |  |  |  |  |  |  |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Application site warmth |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Application site haematoma |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Application site paraesthesia |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Muscle tightness |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | 
| Gastrointestinal discomfort |  |  |  |  |  |  |  | x | x |  |  |  |  | x |  |  |  |  |  |  |  |  | 
| Injection site stinging |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Application site discolouration |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Application site discomfort |  |  |  |  |  | x |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | 
| Hearing impaired |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Medication overuse headache |  |  | x | x |  | x |  |  |  | x |  |  |  |  |  | x |  |  |  |  |  |  | 
| Rhinitis allergic |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x | 
| Nasal inflammation |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  |  | x | x | x | x | x |