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Tamoxifen

More information: STITCH, PubChem (stereo-specific compounds: 1, 2) and possibly Wikipedia

ATC Code: L02BA01

Side effects

Options: Show MedDRA Preferred Terms

Side effect Data for drug Placebo Labels
1 2 3 4 5 6 7 8 9 10 11 12 13 14 15 16 17 18 19
Hot flush very common, 0.8% - 80% 1% - 68% x x x x x x x x x x x x x x x x x x x
Amenorrhoea 16% - 69% x x x x x x x x
Flushing 33% - 46% x x x x x x x x x
Fluid retention 2% - 32% 1% - 30% x x x x x x x x x x x x x x x
Weight decreased 0.5% - 23% 0.2% - 18% x x x x x x x x x
Mood alteration NOS 1.1% - 19.3% x x x x x
Asthenia 1.07% - 18.6% x x x x x x x x
Arthritis 14% - 16.6% x x x x x x
Pharyngitis 13.6% - 14.3% x x x x x x
Arthralgia 11.1% - 15.1% x x x x x x
Vomiting 1.03% - 12.7% x x x x x x x x x x x x x x x x
Vaginal discharge postmarketing, 0.24% - 55% 1% - 35% x x x x x x x x x x x x x x x x x x x
Hypertension 7-11% - 13% x x x x x x
Nausea 1.03% - 26% 24% x x x x x x x x x x x x x x x x x x x
Lymphoedema 9.83% - 11% x x x x x
Oedema peripheral 8-11% - 11.1% x x x x x x x x x x x x x x x x x x
Back pain 9.99% - 10.4% x x x x x x
Urinary tract infection 7.89% - 10.1% x x x x x x
Accidental injury 9.79% - 10.1% x x x x x
Insomnia 9.08% - 9.99% x x x x x x
Leukorrhea 2.78% - 9-13% x x x x x x
Cough increased 8.44% - 9.28% x x x x x
Weight increased 8-9% - 9.22% x x x x x x
Abdominal pain 7-9% - 8.92% x x x x x x
Diarrhoea 6.98% - 8.57% x x x x x x x
Dyspnoea 7.57% - 7.66% x x x x x x x x
Dizziness 7.56% - 7.63% x x x x x x x x x x x x x x x x x x
Osteoporosis 6-7% - 10.5% x x x x x x
Cataract specified 5.89% - 6.88% x x x x x
Hypercholesterolaemia 3.49% - 8.99% x x x x x
Anxiety 5.82% - 6.31% x x x x x x
Infection 6% - 9.22% 5.1% x x x x x x x x x
Dyspepsia 5.46% - 6.66% x x x x x x
Influenza 5.66% - 6.3% x x x x x x
Breast pain 5.46% - 8.12% x x x x x x
Bone pain 5.98% - 6.5% x x x x x x
Sepsis 6% 5.1% x x x x x x x x
Gastrointestinal disorder 5.11% - 6.79% x x x x x
Cataract uncommon, 0.85% - 6.88% x x x x x x x x x x x x x x x
Sinusitis 5.14% - 5.95% x x x x x
Myalgia 5.17% - 5.79% x x x x x x x x x
Vaginal haemorrhage postmarketing, 0.5% - 23% 5.1% - 22% x x x x x x x x x x x x x x x x x x x
Sweating 4.69% - 5.72% x x x x x x
Alopecia 5% - 5.2% 4.4% x x x x x x x x x x x x x x x x x x
Bronchitis 4.95% - 5.4% x x x x x
Arthropathy 4% - 6.69% x x x x x x
Chest pain 4.85% - 6.47% x x x x x x x x x
Menstrual disorder 4% - 6% x x x x x x x x
Paraesthesia 4.69% - 6.95% x x x x x x x x x
Vulvovaginitis 4.85% - 6.27% x x x x x x
Aspartate aminotransferase increased 5% 3% x x x x x x x x
Tumour flare 10% x x x x x x
Oligomenorrhoea 1% - 9% x x x x x x x x
Neoplasm 4.65% - 5.24% x x
Breast neoplasm 4.49% - 5.3% x x x x x x
Cyst 4.46% - 5.24% x x x x x
Vaginal inflammation 4.04% - 5.11% x x x x x
Constipation 4.4% - 8.14% 3.2% x x x x x x x x x x
Anaemia 3.65% - 5.14% x x x x x x x x x x x x
Cough 1% - 4-10% x x x x x x x x x x x x
Fatigue 1% - 18.6% x x x x x x x x x x
Pain 0% - 17.2% x x x x x x x x x x x x
Urinary incontinence 4% x
Vulvovaginal candidiasis 4% x
Cardiovascular disorder 1.23% - 4.11% x x x x x
Nail changes 3% x
Oedema 1% - 4% x x x x x x x x
Fracture 0.711% - 10.2% x x x x x x
Anorexia 1% - 2% x x x x x x x x x
Depression 2% - 13.4% x x x x x x x x
Ovarian cyst 3% x x x x x x x x x x x x x x x
Thrombocytopenia 2% 1% x x x x
Dry mouth 2% x
Creatinine increased 2% 1% x x x x x x x x x
Blood bilirubin increased 2% 1% x x x x x x x x
Thromboembolic event 0.61% - 4.52% x x x x x
Abdominal cramps 1% - 2% x x x x x x x x
Musculoskeletal pain 0% - 3% x x x x x x x
Vaginal dryness 3% x x x x x x x x x
Hypersensitivity postmarketing, 2.5% 2.1% x x x x x x x x x x x x x x x x x x
Hip fracture 0.84% - 0.906% x x x x x
Deep vein thrombosis 0.8% 0.2% x x x x
Platelet count decreased 0.7% - 5.6% 0.3% - 4.7% x x x x x x x x
Hepatitis 1% x x x x x x
Hypercalcaemia 1% x x x x x x x x x x x x x x x x x x x
Pneumonia 1% x
Pruritus vulvae 1% x x x x x x x x x x x x x x x x x
Pulmonary embolism 0.5% 0.2% x x x x
Erectile dysfunction 1% x x x x x x x x x
Phlebitis superficial 0.4% 0% x x x x x x x x x
Endometrial cancer 0.129% - 0.8% x x x x x x x x x x x x x x x x
Angioedema postmarketing x x x x x x x x x x x x x x x x
Erythema multiforme postmarketing x x x x x x x x x x x x x x x x x x
Rash postmarketing, 13% - 12.5% x x x x x x x x x x x x x x x x x x x
Headache postmarketing, 8.05% - 10.2% x x x x x x x x x x x x x x x x x x x
Pancreatitis postmarketing, 1% x x x x x x x x x x x x x x x x x x
Pemphigoid postmarketing, 1% x x x x x x x x x x x x x x x x x x
Stevens-Johnson syndrome postmarketing x x x x x x x x x x x x x x x x
Menstruation irregular postmarketing, 0.8% - 25% 0.2% - 19% x x x x x x x x x x x x
Interstitial pneumonia very rare, postmarketing x x x x x x x x x x x x x x x x
Drug interaction postmarketing x x x x x x x x x x
Adenocarcinoma x x x
Angina pectoris x x x x x
Arrhythmia x
Blister x x
Breast feeding x x
Cholestasis x x x x x x x x x x x
Contusion x
Dysphagia x x x
Dysgeusia x x x
Endometriosis x x x x x x x x x x x
Liver fatty x x x x x x x
Haemorrhage x
Hyperlipidaemia x x
Hyperplasia x x x x x x x x x x x
Hypertriglyceridaemia x
Inflammation x x x
Cramps of lower extremities x x x x x
Leukopenia x x x x x x x
Cutaneous lupus erythematosus x x x x
Macular degeneration x
Menopause x x x x x x
Cramp muscle x
Myocardial infarction x x x x x
Neutropenia x x x x x x x
Night sweats x
Numbness x x
Optic nerve disorder x x x x x
Optic neuritis x x x x x
Peliosis hepatis x x x x x x
Pelvic pain x
Polyp x x x x x x x x x x x
Priapism x
Pruritus x x x x x
Precocious puberty x x x x x x
Retinal disorder x x x x x x x
Swelling x x x x x
Thirst x x x
Thrombosis x x x
Erythema x x x x x x x x x x x x x x
Urticaria x x x
Uterine leiomyoma x x x x x x x x x x x
Vasculitis x
Hepatic failure x x x x
Hepatic function abnormal x
Benign neoplasm x
High density lipoprotein decreased x
Myocardial ischaemia x
Hepatocellular injury x x x x
Hepatic necrosis x x x x
Alanine aminotransferase increased x
Uterine cancer x x x
Uterine polyp x
Porphyria cutanea tarda x x x x
Lightheadedness x x x x x x x x x x x x x x x x x x
Discomfort x x x
Tenderness x x
Visual acuity reduced x x x x x x
Upset stomach x x x
Hepatotoxicity x
Ankle edema x x x
Skin exfoliation x x
Breast cancer male x x x x x x x x
Disease progression x x
Cutaneous vasculitis x x x
Hepatic cyst x x x x x x
Macular oedema x x x x x x
Walking disability x x x
Redness x x x x
Sarcoma uterus x x x x x x x x x x x x x x x
Blindness x x x x x
Paralysis x
Visual disturbance x x x x x x
Throat irritation x
Febrile neutropenia x
Tumour pain x x x x x x x x x x x x x x x x x x x
Myelosuppression x
Accidental ingestion x x
Oestrogenic effect x x
Raised liver function tests x
Endometrial adenocarcinoma x x x x x x x
Sarcoma x x x x x
Ocular toxicity x
Nettle rash x x x
Appetite absent x
Metastatic disease x
Loss of libido x x x x x x x x

Indications

Information about indications was extracted from the indications and usage sections of the labels.

Tamoxifen citrate tablets / Genox, Tablet

Side effects:42
Source:Medsafe

Tamoxifen citrate / TAMOXIFEN

Side effects:46
Source:medicines.org.au

Tamoxifen (as citrate) / Genox

Side effects:48
Source:medicines.org.au

Tamoxifen citrate / NOLVADEX

Side effects:49
Source:medicines.org.au

TAMOXIFEN (TAMOXIFEN CITRATE) / TAMOFEN 20

Side effects:34
Source:Health Canada

TAMOXIFEN (TAMOXIFEN CITRATE) / PMS-TAMOXIFEN

Side effects:41
Source:Health Canada

TAMOXIFEN (TAMOXIFEN CITRATE) / TAMOXIFEN

Side effects:42
Source:Health Canada

TAMOXIFEN (TAMOXIFEN CITRATE) / GEN-TAMOXIFEN TAB 10MG

Side effects:69
Source:Health Canada

TAMOXIFEN (TAMOXIFEN CITRATE) / NOLVADEX-D TAB 20MG

Side effects:70
Source:Health Canada

Tamoxifen

Side effects:99
Source:BC Cancer

tamoxifen citrate / Nolvadex

Side effects:53
Source:FDA

Tamoxifen

Side effects:54
Source:FDA Structured Product Label

tamoxifen citrate / Nolvadex

Side effects:55
Source:FDA

TAMOXIFEN

Side effects:100
Source:FDA Structured Product Label

Tamoxifen

Side effects:102
Source:FDA Structured Product Label

TAMOXIFEN

Side effects:103
Source:FDA Structured Product Label

TAMOXIFEN

Side effects:104
Source:FDA Structured Product Label

TAMOXIFEN

Side effects:104
Source:FDA Structured Product Label

Color scheme:

standard – alternative

    100%
    75%
    50%
    10%
    frequent (1% to 100%)
    infrequent (0.1% to 1%)
    rare (<0.1%)
    postmarketing
    0%
    no frequency information
    not found on label