Levetiracetam
Side effects
Options:
Show MedDRA Preferred Terms,
display all 86 labels
Side effect
|
Data for drug
|
Placebo
|
Labels
|
|
1
|
2
|
3
|
4
|
5
|
6
|
7
|
8
|
9
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10
|
11
|
12
|
13
|
14
|
15
|
16
|
17
|
18
|
19
|
20
|
Accidental injury
|
10.3% - 17%
|
10% - 16.5%
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Vomiting
|
2.2% - 15%
|
2% - 13%
|
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Headache
|
1.19% - 19%
|
0.57% - 15%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Nasopharyngitis
|
common, 7% - 15%
|
5% - 12%
|
|
x
|
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Infection
|
13% - 13.2%
|
7.4% - 8%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Somnolence
|
1.67% - 23%
|
0% - 11%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Aggression
|
postmarketing, 10%
|
5%
|
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
Fatigue
|
very common, 10% - 15%
|
5% - 10%
|
|
x
|
|
x
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Asthenia
|
1.3% - 15%
|
0% - 10%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Cough
|
9% - 11%
|
5% - 7%
|
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Nasal congestion
|
9%
|
2%
|
|
|
|
|
|
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Abdominal pain upper
|
9%
|
8%
|
|
|
|
|
|
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Diarrhoea
|
4.2% - 8%
|
5% - 7%
|
|
x
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Gastrointestinal disorder
|
8%
|
7%
|
|
|
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Personality disorder
|
common, 8%
|
7%
|
x
|
|
|
|
x
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
x
|
x
|
Decreased appetite
|
8%
|
2%
|
|
|
|
|
|
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Dizziness
|
1% - 9.2%
|
0% - 5%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Pain
|
6% - 7%
|
3% - 6.6%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Pharyngitis
|
5.7% - 10%
|
0% - 8%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Abnormal behaviour
|
postmarketing, 7%
|
4%
|
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
Pharyngolaryngeal pain
|
7%
|
4%
|
|
|
|
|
|
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Irritability
|
postmarketing — 1.67% - 12%
|
0% - 2%
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Lethargy
|
6%
|
2%
|
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Agitation
|
4% - 6%
|
1%
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Eczema
|
common
|
|
|
|
|
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
Nausea
|
4.2% - 5%
|
3% - 4.6%
|
|
x
|
|
|
x
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
x
|
x
|
Myalgia
|
common
|
|
|
|
|
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
Disturbance in attention
|
common
|
|
|
|
|
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
Memory impairment
|
common
|
|
|
|
|
|
x
|
x
|
x
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
Vision blurred
|
common
|
|
|
|
|
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
Balance disorder
|
common
|
|
|
|
|
|
x
|
x
|
x
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
Influenza
|
3% - 8%
|
1% - 6%
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Albuminuria
|
4%
|
0%
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Back pain
|
4%
|
4.6%
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Depression
|
1.67% - 5%
|
0% - 2.3%
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Ecchymosis
|
1.5% - 4%
|
1% - 1.1%
|
x
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Gastroenteritis
|
1.2% - 4%
|
0% - 2%
|
|
x
|
|
|
|
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Head injury
|
4%
|
0%
|
|
|
|
|
|
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Nervousness
|
1.67% - 10%
|
0% - 2%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Rhinitis
|
2% - 13%
|
0% - 8%
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Abdominal pain
|
3.7%
|
5.1%
|
|
x
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
x
|
x
|
Anorexia
|
2.4% - 13%
|
2% - 8%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Ataxia
|
2.5% - 3%
|
1% - 1.4%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Constipation
|
3%
|
1%
|
|
x
|
|
|
|
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Contusion
|
3%
|
1%
|
|
|
|
|
|
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Vertigo
|
2.5% - 5%
|
1% - 3%
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Mood swings
|
common, 1.6% - 6%
|
0% - 4%
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Coordination abnormal
|
3%
|
2%
|
|
|
|
|
|
x
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Convulsion
|
2.38% - 6%
|
2.85% - 6.8%
|
x
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Dyspepsia
|
2.8%
|
3.4%
|
|
x
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
x
|
x
|
Amblyopia
|
1.2% - 2%
|
0% - 1.4%
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Amnesia
|
1.6% - 2%
|
0.3% - 1%
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Anxiety
|
1.6% - 3.33%
|
1% - 2%
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Arthralgia
|
2%
|
0%
|
|
x
|
|
|
|
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Asthma
|
2%
|
1%
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Neck pain
|
2% - 8%
|
1% - 2%
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Confusional state
|
postmarketing, 2%
|
0%
|
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Conjunctivitis
|
2% - 3%
|
0% - 2%
|
|
|
|
|
|
|
x
|
x
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dehydration
|
2%
|
1%
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Diplopia
|
1.67% - 2.4%
|
0% - 1.7%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Ear pain
|
2%
|
0% - 1%
|
|
|
|
|
|
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hostility
|
2% - 12%
|
0.6% - 6%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Paraesthesia
|
1.9% - 2%
|
1% - 1.7%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Pruritus
|
common, 2%
|
0%
|
|
|
|
|
x
|
|
|
x
|
x
|
|
x
|
|
|
|
|
|
|
|
x
|
x
|
Sinusitis
|
2% - 2.1%
|
0.9% - 1%
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Viral infection
|
2%
|
1%
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Vesiculobullous rash
|
2%
|
0%
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Hyperreflexia
|
2%
|
1%
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Skin discolouration
|
2%
|
0%
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Affect lability
|
2%
|
1%
|
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Urine abnormality
|
2%
|
1%
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Depressed mood
|
1.67% - 2%
|
0%
|
|
|
x
|
x
|
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Joint sprain
|
2%
|
1%
|
|
|
|
|
|
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Face oedema
|
2%
|
1%
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Cough increased
|
2% - 11%
|
1% - 7%
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hypersomnia
|
1.67% - 2%
|
0%
|
|
|
x
|
x
|
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Insomnia
|
1.67% - 5%
|
0% - 3%
|
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Urinary tract infection
|
1.9%
|
3.4%
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Tooth disorder
|
1.5%
|
0.6%
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Tremor
|
1.5%
|
1.7%
|
|
x
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
x
|
x
|
Thinking abnormal
|
1.5%
|
1.4%
|
x
|
x
|
|
|
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
x
|
x
|
Bronchitis
|
1.3%
|
1.4%
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Chest pain
|
1.3%
|
1.1%
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Body temperature increased
|
1.3%
|
1.7%
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Drug level increased
|
1.3%
|
0.9%
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Gingivitis
|
1.2%
|
0.6%
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Otitis media
|
1.2%
|
0.9%
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Weight increased
|
1.2%
|
1.1%
|
|
x
|
|
|
|
|
|
x
|
x
|
|
x
|
|
|
|
|
|
|
|
x
|
x
|
Psychotic disorder
|
postmarketing, 1%
|
0%
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
x
|
Agranulocytosis
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
x
|
|
|
Alopecia
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Anger
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
x
|
Mental disorder
|
postmarketing
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Dyskinesia
|
postmarketing
|
|
|
|
|
|
|
x
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
|
x
|
x
|
|
|
Eosinophilia
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
Toxic epidermal necrolysis
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Erythema multiforme
|
postmarketing
|
|
|
|
|
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Hallucination
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
x
|
Blood disorder
|
postmarketing
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Hepatitis
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Hyponatraemia
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Leukopenia
|
postmarketing
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Nervous system disorder
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Neutropenia
|
postmarketing
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Pancreatitis
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Pancytopenia
|
postmarketing
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Stevens-Johnson syndrome
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Suicide
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
x
|
Suicide attempt
|
postmarketing
|
|
|
|
x
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
x
|
Thrombocytopenia
|
postmarketing, common
|
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Weight decreased
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Choreoathetosis
|
postmarketing
|
|
|
|
|
|
|
x
|
|
|
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Hepatic failure
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Panic attack
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
|
Liver function test abnormal
|
postmarketing
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Muscular weakness
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
|
|
Malnutrition
|
postmarketing
|
|
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
Suicidal ideation
|
postmarketing
|
|
|
|
x
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
x
|
Drug interaction
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Completed suicide
|
postmarketing
|
|
|
|
x
|
x
|
|
|
|
x
|
|
x
|
x
|
|
|
|
|
|
|
|
x
|
|
Raised liver function tests
|
postmarketing
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Suicidal behaviour
|
postmarketing
|
|
|
|
x
|
x
|
|
|
|
x
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Common cold
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Connective tissue disorder
|
|
|
|
|
x
|
x
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
Depersonalisation
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Drowsiness
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Drug abuse
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Dysmenorrhoea
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Epistaxis
|
|
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Rash
|
0% - 2.8%
|
1.14% - 4%
|
x
|
x
|
|
|
x
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
x
|
x
|
Eye disorder
|
|
|
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
x
|
Hypersensitivity
|
|
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Immune system disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Liver disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Mediastinal disorder
|
|
|
|
|
|
|
|
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Metabolic disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Fungal infection
|
|
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
|
Neurosis
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Pregnancy
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Skin disorder
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Status epilepticus
|
|
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Toothache
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Upper respiratory tract infection
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Urinary incontinence
|
|
|
|
x
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
x
|
x
|
Apathy
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Lower respiratory tract infection
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Mouth ulceration
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Paranoid reaction
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Unspecified disorder of skin and subcutaneous tissue
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Community acquired infection
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Function kidney decreased
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Teratogenicity
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Psychiatric symptom
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Antisocial behaviour
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Withdrawal seizures
|
|
|
|
|
|
|
|
x
|
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
|
Euphoric mood
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Throat sore
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Hepatobiliary disease
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Psychotic depression
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Hyperkinesia
|
|
|
|
x
|
|
|
x
|
|
|
x
|
x
|
x
|
x
|
|
|
|
|
|
|
|
x
|
x
|
Progesterone levels
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Dependence
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Gait disturbance
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
White blood cell count decreased
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
x
|
Infestation NOS
|
|
|
|
|
x
|
x
|
x
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Blood and lymphatic system disorders
|
|
|
|
|
|
|
|
|
|
|
|
x
|
x
|
|
|
|
|
|
|
|
|
|
Ear and labyrinth disorders
|
|
|
|
|
x
|
x
|
|
x
|
x
|
|
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
x
|
|
Procedural complication
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Respiratory failure
|
|
|
|
|
|
|
x
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Rhinorrhoea
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
|
Indications
Information about indications was extracted from the indications and usage sections of the labels.
Side effects: | 30 |
Source: | Health Canada |
---|
Side effects: | 45 |
Source: | FDA Structured Product Label |
---|
Side effects: | 46 |
Source: | FDA Structured Product Label |
---|
Side effects: | 48 |
Source: | FDA Structured Product Label |
---|
Side effects: | 51 |
Source: | FDA Structured Product Label |
---|
Side effects: | 58 |
Source: | FDA Structured Product Label |
---|
Side effects: | 77 |
Source: | FDA Structured Product Label |
---|
Side effects: | 77 |
Source: | FDA |
---|
Side effects: | 78 |
Source: | FDA Structured Product Label |
---|
Side effects: | 78 |
Source: | EMA |
---|
Side effects: | 79 |
Source: | EMA |
---|
Side effects: | 81 |
Source: | FDA Structured Product Label |
---|
Side effects: | 83 |
Source: | FDA Structured Product Label |
---|
Side effects: | 83 |
Source: | FDA Structured Product Label |
---|
Side effects: | 83 |
Source: | FDA Structured Product Label |
---|
Side effects: | 84 |
Source: | FDA Structured Product Label |
---|
Side effects: | 85 |
Source: | FDA Structured Product Label |
---|
Side effects: | 87 |
Source: | FDA Structured Product Label |
---|
Side effects: | 92 |
Source: | FDA Structured Product Label |
---|
Side effects: | 103 |
Source: | medicines.org.au |
---|
Color scheme:
standard – alternative
|
|
100%
|
|
|
75%
|
|
|
50%
|
|
|
10%
|
|
|
frequent (1% to 100%)
|
|
|
infrequent (0.1% to 1%)
|
|
|
rare (<0.1%)
|
|
|
postmarketing
|
|
|
0%
|
|
|
no frequency information
|
|
|
not found on label
|